Jason H. Mendler, M.D., Ph.D.

Jason H. Mendler, M.D., Ph.D.

Contact Information

Box 704

Administrative: (585) 275-4099
Fax: (585) 273-1051

Professional Bio

Jason Harold Mendler, MD, PhD, Assistant Professor of Oncology, received his bachelor's degree, Summa Cum Laude, from Washington University in St. Louis, Missouri. He then went on to earn his PhD in Genetics and his medical degree at the University of Rochester School of Medicine and Dentistry in Rochester, New York. Prior to joining Wilmot Cancer Center, Dr. Mendler completed his residency at and served as chief resident of the University of Rochester Medical Center, Department of Medicine. Most recently, he completed a clinical fellowship in oncology at Ohio State University Medical Center in Columbus, Ohio and he served one year on the faculty as a clinical instructor.

The recipient of numerous awards and honors, Dr. Mendler has also authored several oncology-related publications. His areas of clinical interest include acute leukemia, CML, MDS, bone marrow transplant and myclopoliferative diseases. Dr. Mendler is certified by the American Board of Internal Medicine.

Awards & Honors (National)

ASH news daily author | ASH 2010
Arnold P. Gold Foundation 2004 Humanism in Medicine Essay contest-2nd prize | Rochester, NY 2004

Awards & Honors (Local)

James 14th Annual Scientific Meeting award for one of top 3 Translational Research Poster | The Ohio State University Comprehensive Cancer Center 2012
James V. Warren Award for accomplishments as the most outstanding research fellow in the Department of Internal Medicine | The Ohio State University | Columbus, Ohio 2011
Distinction in research, Internal Medicine Residency Program | University of Rochester | Rochester, NY 2008
Raphael Dolin Resident Research Award for dedication to patient care, critical scholarship, and teaching | University of Rochester | Rochester, NY 2008
Rochester city-wide Internal Medicine resident poster day 1st place, scientific division | Rochester, NY 2007
Class of 1990 Resident Teaching Award | voted on by the 4th year medical students at the University of R | Rochester, NY 2007
: University of Rochester School of Medicine Class of 1976 Prize (In | University of Rochester | Rochester, NY 2005
Alpha Omega Alpha | University Of Rochester School of Medicine | Rochester, NY 2004
Phi Beta Kappa | Washington University in St. Louis | St. Louis, MO 1997
Summa Cum Laude | Washington University in St. Louis | St. Louis, MO 1997

Recent Journal Articles

Showing the 5 most recent journal articles. 19 available »

2015 Oct
Khalife J, Radomska HS, Santhanam R, Huang X, Neviani P, Saultz J, Wang H, Wu YZ, Alachkar H, Anghelina M, Dorrance A, Curfman J, Bloomfield CD, Medeiros BC, Perrotti D, Lee LJ, Lee RJ, Caligiuri MA, Pichiorri F, Croce CM, Garzon R, Guzman ML, Mendler JH, Marcucci G. "Pharmacological targeting of miR-155 via the NEDD8-activating enzyme inhibitor MLN4924 (Pevonedistat) in FLT3-ITD acute myeloid leukemia." Leukemia. 2015 Oct; 29(10):1981-92. Epub 2015 May 14.
2015 Mar
Niederwieser C, Kohlschmidt J, Volinia S, Whitman SP, Metzeler KH, Eisfeld AK, Maharry K, Yan P, Frankhouser D, Becker H, Schwind S, Carroll AJ, Nicolet D, Mendler JH, Curfman JP, Wu YZ, Baer MR, Powell BL, Kolitz JE, Moore JO, Carter TH, Bundschuh R, Larson RA, Stone RM, Mrózek K, Marcucci G, Bloomfield CD. "Prognostic and biologic significance of DNMT3B expression in older patients with cytogenetically normal primary acute myeloid leukemia." Leukemia. 2015 Mar; 29(3):567-75. Epub 2014 Sep 10.
Sivagnanalingam U, Balys M, Eberhardt A, Wang N, Myers JR, Ashton JM, Becker MW, Calvi LM, Mendler JH. "Residual Disease in a Novel Xenograft Model of RUNX1-Mutated, Cytogenetically Normal Acute Myeloid Leukemia." PloS one. 2015 10(7):e0132375. Epub 2015 Jul 15.
2014 Aug
Becker H, Maharry K, Mrózek K, Volinia S, Eisfeld AK, Radmacher MD, Kohlschmidt J, Metzeler KH, Schwind S, Whitman SP, Mendler JH, Wu YZ, Nicolet D, Paschka P, Powell BL, Carter TH, Wetzler M, Kolitz JE, Carroll AJ, Baer MR, Caligiuri MA, Stone RM, Marcucci G, Bloomfield CD. "Prognostic gene mutations and distinct gene- and microRNA-expression signatures in acute myeloid leukemia with a sole trisomy 8." Leukemia. 2014 Aug; 28(8):1754-8. Epub 2014 Mar 21.
2014 Jun
Whitman SP, Kohlschmidt J, Maharry K, Volinia S, Mrózek K, Nicolet D, Schwind S, Becker H, Metzeler KH, Mendler JH, Eisfeld AK, Carroll AJ, Powell BL, Carter TH, Baer MR, Kolitz JE, Park IK, Stone RM, Caligiuri MA, Marcucci G, Bloomfield CD. "GAS6 expression identifies high-risk adult AML patients: potential implications for therapy." Leukemia. 2014 Jun; 28(6):1252-8. Epub 2013 Dec 11.

Current Appointments

Assistant Professor - Department of Medicine, Hematology/Oncology (SMD) - Primary
Assistant Professor - Cancer Center


Medical Oncology - American Board of Internal Medicine
Internal Medicine - American Board of Internal Medicine


MD | Medicine | University or Rochester School of Medince and Dentistry2005
PhD | Genetics | University of Rochester School of Medicine and Dentistry2004
BA | Biology | Washington University in St. Louis1997

Post-Doctoral Training & Residency

Fellowship in Medical Oncology at Ohio State University Medical Center07/01/2009 - 07/14/2011
Residency in Internal Medicine at University of Rochester Medical Center06/24/2006 - 06/23/2008
Internship in Internal Medicine at University of Rochester Medical Center06/24/2005 - 06/23/2006