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Edward M. Schwarz, Ph.D.

Contact Information

Phone Numbers

Appointment: (585) 276-3000

Research Labs

Biography

Dr. Edward Schwarz is the Burton Professor of Orthopaedics and Director of the Center for Musculoskeletal Research at the University of Rochester Medical Center, in Rochester, NY. His laboratory focuses on inflammatory bone loss, such as that seen in rheumatoid arthritis, infections, tumor metastasis and wear debris-induced osteolysis around loose prosthetic implants.

Dr. Schwarz is also a leader in orthopaedic biologic therapy and stem cell research, for which his lab has developed a novel passive immunization for MRSA and revitalizing allograft approaches for bone and tendon regeneration.

Dr. Schwarz's lab is also interested in developing translational in vivo imaging outcome measures include near infrared imaging of lymphatic flow to detect arthritic flare, and cone beam CT to assess bone healing in patients with orthopaedic implants. More recently, Dr. Schwarz's lab has combined these biologic therapy technologies and outcome measures with biocompatible carriers and stem cells to generate novel tissue engineering constructs for bone, cartilage, ligament and tendon.

Research

Dr. Edward Schwarz is the Burton Professor of Orthopaedics and Director of the Center for Musculoskeletal Research at the University of Rochester Medical Center, in Rochester, NY. His laboratory focuses on inflammatory bone loss, such as that seen in rheumatoid arthritis, infections, tumor metastasis and wear debris-induced osteolysis around loose prosthetic implants.
Dr. Schwarz is also a leader in orthopaedic biologic therapy and stem cell research, for which his lab has developed a novel passive immunization for MRSA and revitalizing allograft approaches for bone and tendon regeneration.

Dr. Schwarz's lab is also interested in developing translational in vivo imaging outcome measures include near infrared imaging of lymphatic flow to detect arthritic flare, and cone beam CT to assess bone healing in patients with orthopaedic implants. More recently, Dr. Schwarz's lab has combined these biologic therapy technologies and outcome measures with biocompatible carriers and stem cells to generate novel tissue engineering constructs for bone, cartilage, ligament and tendon.

Credentials

Faculty Appointments

Education

1988
BS | Worcester Polytech Inst
Biology

1990
MA | Einstein College Medicine
Immunology, All Other

1993
PhD | Einstein College Medicine
Immunology, All Other

Awards

2007
J.R. Neff Award, Musculoskeletal Research Foundation

2005
Orthopaedic Research Society's Kappa Delta Young Investigator Award

2003
Orthopaedic Research Society's Harris Award

1999
University of Rochester Nominee for the Elison Award.

1999
University of Rochester Nominee for the Sinshimmer Award.

1999
New Investigator Research Award, The Association of Bone & Joint Surgeons .

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Publications

Journal Articles

9/2/2017
Ishikawa M, de Mesy Bentley KL, McEntire BJ, Bal BS, Schwarz EM, Xie C. "Surface topography of silicon nitride affects antimicrobial and osseointegrative properties of tibial implants in a murine model." Journal of biomedical materials research. Part A.. 2017 Sep 2; Epub 2017 Sep 02.

9/2017
Zhang L, Wang T, Chang M, Kaiser C, Kim JD, Wu T, Cao X, Zhang X, Schwarz EM. "Teriparatide Treatment Improves Bone Defect Healing Via Anabolic Effects on New Bone Formation and Non-Anabolic Effects on Inhibition of Mast Cells in a Murine Cranial Window Model." Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.. 2017 Sep 0; 32(9):1870-1883. Epub 2017 Jul 19.

6/2017
Bouta EM, Kuzin I, de Mesy Bentley K, Wood RW, Rahimi H, Ji RC, Ritchlin CT, Bottaro A, Xing L, Schwarz EM. "Brief Report: Treatment of Tumor Necrosis Factor-Transgenic Mice With Anti-Tumor Necrosis Factor Restores Lymphatic Contractions, Repairs Lymphatic Vessels, and May Increase Monocyte/Macrophage Egress." Arthritis & rheumatology.. 2017 Jun 0; 69(6):1187-1193. Epub 2017 Apr 04.

Books & Chapters

2003
Chapter Title: Signal Transduction in Rheumatic Diseases
Book Title: Kelley's Textbook of Rheumatology
Author List: Schwarz, E.M.
Published By: W.B. Saunders Company2003

2003
Chapter Title: Biologic Agents as Antiresorptive Therapy
Book Title: Molecular Biology in Orthopaedics
Author List: Schwarz, E.M.
Edited By: Rosier, R.N. & Evans, C.H.
Published By: American Academy of Orthopaedic Surgeons: 2412003

2001
Book Title: Implant Wear in Total Joint Replacement
Author List: Wright. T.M. Goodman, S.B., Schwarz, E.M.
Published By: American Academy of Orthopaedic Surgeons2001

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