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Edward M. Schwarz, Ph.D.

Contact Information

Phone Numbers

Appointment: (585) 276-3000

Biography

Dr. Edward Schwarz is the Burton Professor of Orthopaedics and Director of the Center for Musculoskeletal Research at the University of Rochester Medical Center, in Rochester, NY. His laboratory focuses on inflammatory bone loss, such as that seen in rheumatoid arthritis, infections, tumor metastasis and wear debris-induced osteolysis around loose prosthetic implants. Dr. Schwarz is also a leader in orthopaedic biologic therapy and stem cell research, for which his lab has developed a novel passive immunization for MRSA and revitalizing allograft approaches for bone and tendon regeneration. Dr. Schwarz's lab is also interested in developing translational in vivo imaging outcome measures include near infrared imaging of lymphatic flow to detect arthritic flare, and cone beam CT to assess bone healing in patients with orthopaedic implants. More recently, Dr. Schwarz's lab has combined these biologic therapy technologies and outcome measures with biocompatible carriers and stem cells to generate novel tissue engineering constructs for bone, cartilage, ligament and tendon.

Research

Dr. Edward Schwarz is the Burton Professor of Orthopaedics and Director of the Center for Musculoskeletal Research at the University of Rochester Medical Center, in Rochester, NY. His laboratory focuses on inflammatory bone loss, such as that seen in rheumatoid arthritis, infections, tumor metastasis and wear debris-induced osteolysis around loose prosthetic implants. Dr. Schwarz is also a leader in orthopaedic biologic therapy and stem cell research, for which his lab has developed a novel passive immunization for MRSA and revitalizing allograft approaches for bone and tendon regeneration. Dr. Schwarz's lab is also interested in developing translational in vivo imaging outcome measures include near infrared imaging of lymphatic flow to detect arthritic flare, and cone beam CT to assess bone healing in patients with orthopaedic implants. More recently, Dr. Schwarz's lab has combined these biologic therapy technologies and outcome measures with biocompatible carriers and stem cells to generate novel tissue engineering constructs for bone, cartilage, ligament and tendon.

Credentials

Faculty Appointments

Education

1988
BS | Worcester Polytech Inst
Biology

1993
PhD | Einstein College Medicine
Immunology, All Other

1990
MA | Einstein College Medicine
Immunology, All Other

Awards

2007
J.R. Neff Award, Musculoskeletal Research Foundation

2005
Orthopaedic Research Society's Kappa Delta Young Investigator Award

2003
Orthopaedic Research Society's Harris Award

1999
University of Rochester Nominee for the Elison Award.

1999
University of Rochester Nominee for the Sinshimmer Award.

1999
New Investigator Research Award, The Association of Bone & Joint Surgeons .

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Publications

Journal Articles

4/19/2017
Schwarz EM. "Confirmation of Sexual Dimorphisms in Metal Hypersensitivity and Joint Pain Following Total Joint Arthroplasty: Commentary on an article by Marco S. Caicedo, PhD, et al.: "Females with Unexplained Joint Pain Following Total Joint Arthroplasty Exhibit a Higher Rate and Severity of Hypersensitivity to Implant Metals Compared with Males. Implications of Sex-Based Bioreactivity Differences"." The Journal of bone and joint surgery. American volume.. 2017 Apr 19; 99(8):e41.

3/20/2017
Farnsworth CW, Schott EM, Jensen SE, Zukoski J, Benvie AM, Refaai MA, Kates SL, Schwarz EM, Zuscik MJ, Gill SR, Mooney RA. "Adaptive upregulation of Clumping Factor A (ClfA) by S. aureus in the obese, type 2 diabetic host mediates increased virulence." Infection and immunity.. 2017 Mar 20; Epub 2017 Mar 20.

2/8/2017
Chen X, Wang Z, Duan N, Zhu G, Schwarz EM, Xie C. "Osteoblast-osteoclast interactions." Connective tissue research.. 2017 Feb 8; :1-9. Epub 2017 Feb 08.

Books & Chapters

2003
Chapter Title: Signal Transduction in Rheumatic Diseases
Book Title: Kelley's Textbook of Rheumatology
Author List: Schwarz, E.M.
Published By: W.B. Saunders Company2003

2003
Chapter Title: Biologic Agents as Antiresorptive Therapy
Book Title: Molecular Biology in Orthopaedics
Author List: Schwarz, E.M.
Edited By: Rosier, R.N. & Evans, C.H.
Published By: American Academy of Orthopaedic Surgeons: 2412003

2001
Book Title: Implant Wear in Total Joint Replacement
Author List: Wright. T.M. Goodman, S.B., Schwarz, E.M.
Published By: American Academy of Orthopaedic Surgeons2001

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