Jiyong Zhao, Ph.D.

Jiyong Zhao, Ph.D.

Contact Information

University of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 633
Rochester, NY 14642

Office: (585) 273-1453
Lab: (585) 273-2414
Administrative: (585) 273-1440
Fax: (585) 273-1450

Journal Articles

Showing all 26 journal articles available.

2016 Apr
Chen L, Oleksyn D, Pulvino M, Sanz I, Ryan D, Ryan C, Lin CS, Poligone B, Pentland AP, Ritchlin C, Zhao J. "A critical role for the protein kinase PKK in the maintenance of recirculating mature B cells and the development of B1 cells." Immunology letters. 2016 Apr; 172:67-78. Epub 2016 Feb 26.
2015 Jun 20
Pulvino M, Chen L, Oleksyn D, Li J, Compitello G, Rossi R, Spence S, Balakrishnan V, Jordan C, Poligone B, Casulo C, Burack R, Shapiro JL, Bernstein S, Friedberg JW, Deshaies RJ, Land H, Zhao J. "Inhibition of COP9-signalosome (CSN) deneddylating activity and tumor growth of diffuse large B-cell lymphomas by doxycycline." Oncotarget. 2015 Jun 20; :14796-14813. Epub 2015 Jun 20.
2015 Mar
Poligone B, Gilmore ES, Alexander C, Oleksyn D, Gillespie K, Zhao J, Ibrahim S, Pentland AP, Brown M, Chen L. "PKK suppresses tumor growth and is decreased in squamous cell carcinoma of the skin." The Journal of investigative dermatology. 2015 Mar; 135(3):869-76. Epub 2014 Oct 06.
2014 Oct
Kim SW, Schifano M, Oleksyn D, Jordan CT, Ryan D, Insel R, Zhao J, Chen L. "Protein kinase C-associated kinase regulates NF-?B activation through inducing IKK activation." International journal of oncology. 2014 Oct; 45(4):1707-14. Epub 2014 Aug 04.
2013 Apr
Oleksyn D, Pulvino M, Zhao J, Misra R, Vosoughi A, Jenks S, Tipton C, Lund F, Schwartz G, Goldman B, Mohan C, Mehta K, Mehta M, Leitgets M, Sanz I, Chen L. "Protein kinase C? is required for lupus development in Sle mice." Arthritis and rheumatism. 2013 Apr; 65(4):1022-31.
2012 Aug 23
Pulvino M, Liang Y, Oleksyn D, Deran M, Van Pelt E, Shapiro J, Sanz I, Chen L, Zhao J. "Inhibition of proliferation and survival of diffuse large B-cell lymphoma cells by a small-molecule inhibitor of the ubiquitin-conjugating enzyme Ubc13-Uev1A." Blood. 2012 Aug 23; 120(8):1668-77. Epub 2012 Jul 12.
2008 Feb 1
Kim SW, Oleksyn DW, Rossi RM, Jordan CT, Sanz I, Chen L, Zhao J. "Protein kinase C-associated kinase is required for NF-kappaB signaling and survival in diffuse large B-cell lymphoma cells." Blood. 2008 Feb 1; 111(3):1644-53. Epub 2007 Nov 19.
2008 Jan
DeRan M, Pulvino M, Greene E, Su C, Zhao J. "Transcriptional activation of histone genes requires NPAT-dependent recruitment of TRRAP-Tip60 complex to histone promoters during the G1/S phase transition." Molecular and cellular biology. 2008 Jan; 28(1):435-47. Epub 2007 Oct 29.
2006 Aug
Le XF, Bedrosian I, Mao W, Murray M, Lu Z, Keyomarsi K, Lee MH, Zhao J, Bast RC. "Anti-HER2 antibody trastuzumab inhibits CDK2-mediated NPAT and histone H4 expression via the PI3K pathway." Cell cycle. 2006 Aug; 5(15):1654-61. Epub 2006 Aug 01.
2004 Jun
Zhao J. "Coordination of DNA synthesis and histone gene expression during normal cell cycle progression and after DNA damage." Cell cycle. 2004 Jun; 3(6):695-7. Epub 2004 Jun 21.
2004 Mar 10
Su C, Gao G, Schneider S, Helt C, Weiss C, O'Reilly MA, Bohmann D, Zhao J. "DNA damage induces downregulation of histone gene expression through the G1 checkpoint pathway." The EMBO journal. 2004 Mar 10; 23(5):1133-43. Epub 2004 Feb 19.
2004 Jan
Barbie DA, Kudlow BA, Frock R, Zhao J, Johnson BR, Dyson N, Harlow E, Kennedy BK. "Nuclear reorganization of mammalian DNA synthesis prior to cell cycle exit." Molecular and cellular biology. 2004 Jan; 24(2):595-607.
2003 Apr
Gao G, Bracken AP, Burkard K, Pasini D, Classon M, Attwooll C, Sagara M, Imai T, Helin K, Zhao J. "NPAT expression is regulated by E2F and is essential for cell cycle progression." Molecular and cellular biology. 2003 Apr; 23(8):2821-33.
2000 Sep 15
Zhao J, Kennedy BK, Lawrence BD, Barbie DA, Matera AG, Fletcher JA, Harlow E. "NPAT links cyclin E-Cdk2 to the regulation of replication-dependent histone gene transcription." Genes & development. 2000 Sep 15; 14(18):2283-97.
Siwicki, J.; Hedberg, Y.; Nowak, R.; Loden, M.; Zhao, J.; Landberg, G.; Roos, G. "Spontaneously immortalized IL-2 dependent T cell lines demonstrate p16 overexpression, normal pRb/p53 and upregulation of cyclins E or D2." Exp. Gernotol. 2000; 35: 375-388. Link
1998 Feb 15
Zhao J, Dynlacht B, Imai T, Hori T, Harlow E. "Expression of NPAT, a novel substrate of cyclin E-CDK2, promotes S-phase entry." Genes & development. 1998 Feb 15; 12(4):456-61.
1995 Mar
Wang Y, Zhao J, Clapper J, Martin LD, Du C, DeVore ER, Harkins K, Dobbs DL, Benbow RM. "Mimosine differentially inhibits DNA replication and cell cycle progression in somatic cells compared to embryonic cells of Xenopus laevis." Experimental cell research. 1995 Mar; 217(1):84-91.
1994 Jul
Zhao J, Benbow RM. "Inhibition of DNA replication in cell-free extracts of Xenopus laevis eggs by extracts of Xenopus laevis oocytes." Developmental biology. 1994 Jul; 164(1):52-62.
1993 Oct 12
Zhao J, Benbow RM. "An inhibitor of DNA topoisomerase I from Xenopus laevis ovaries." Biochemistry. 1993 Oct 12; 32(40):10622-8.
1992 Oct
Benbow RM, Zhao J, Larson DD. "On the nature of origins of DNA replication in eukaryotes." BioEssays : news and reviews in molecular, cellular and developmental biology. 1992 Oct; 14(10):661-70.
1990 Jun
Zhao JY, Ford CF, Glatz CE, Rougvie MA, Gendel SM. "Polyelectrolyte precipitation of beta-galactosidase fusions containing poly-aspartic acid tails." Journal of biotechnology. 1990 Jun; 14(3-4):273-83.
Benbow, R. M.; Poll, E. H. A.; Zhao, J.; Marini, N. J.; Stowers, D. J. "DNA unwinding and strand synthesis during replication in Xenopus laevis embryos." Papis, T.S. (ed) Gene Regulation and AIDS: Transcriptional Activation, Retroviruses, and Pathogenesis. Portfolio Publishing Company, Houston. 1990; : 69-86. Link
Zhang, S.; Zhao, J.; Chen, Y.; Wang, Z. "Degradation of phenanthrene by Pseudomonas sp. P12." Acta Environmental Science Sinica. 1989; 9: 80-85. Link
Wu, Y.; Zhang, S.; Ma, G.; Song, D.; Zhao, J. "Biosynthesis of indigo involving transferring naphthalene-degrading plasmid DNA from Pseudomonas to E. coli. 16,". Acta Genetics Sinica. 1989; 16: 318-324. Link
1988 Mar
Zhu XM, Zhao JY, Luo QX, Wang ZT. "[Analysis of degradative plasmids by pyrolysis gas liquid chromatography]." Wei sheng wu xue bao = Acta microbiologica Sinica. 1988 Mar; 28(1):62-7.
Zhao, J.; Wang, Z.; Jian, H. "Isolation of a naphthalene-degrading plasmid and its in situ transfer among bacteria in a waste water treatment plant." Acta Environmental Science Sinica. 1988; 8: 84-92. Link


Zhao, J. "Identification of protein-protein interactions by screening cDNA expression libraries.". Protein-Protein Interactions, A Molecular Cloning Manual, 2ed edition. New York: Cold Spring Harbor Laboratory Press, 2004.
Benbow, R. M., Poll, E. H. A., Zhao, J., Marini, N. J. and Stowers, D. J. "DNA unwinding and strand synthesis during replication in Xenopus laevis embryos. in Papis, T.S.". Gene Regulation & AIDS: Transcriptional Activation, Retroviruses, & Pathogensis. Houston.: Portfolio Publishing Company, 1990. 69-86