Craig A. Mullen, M.D., Ph.D.

Contact Information

Phone Numbers

Office: (585) 275-2981

Fax: (585) 273-1039

A member of the University of Rochester Medical Faculty Group

An Accountable Health Partner

Accepting New Patients

Locations

601 Elmwood Ave, Floor 6
Golisano Childrens' Hosital
Rochester, NY 14642-0001

Pediatric Oncology: (585) 275-2981

Faculty Appointments

Professor - Department of Pediatrics , Hematology and Oncology (SMD)
Professor - Cancer Center - Joint
Professor - Department of Microbiology and Immunology (SMD) - Joint

Patient Care Settings

Cancer, Pediatrics

Biography

Acute Lymphoblastic Leukemia
Bone Marrow Transplantation
Childhood Cancer
Infections in Immunocompromised Hosts
Biological Therapies of Cancer
Use of Computer Technology To Improve Drug Compliance

Professional Background

Dr. Mullen serves as the Chief of the Pediatric Hematology / Oncology Division. He is also the Director the Fellowship Program. He has joint appointments as Professor in both the Department of Microbiology and Immunology and Professor in the Department of Oncology.

Research

Dr. Mullen current research work examines the bone marrow microenvironment of acute lymphoblastic leukemia. The current goal of the work is to identify the molecular mechanisms by which nonmalignant cells in the marrow microenvironment that provide antiapoptotic support for leukemia cells. Ultimately this may identify new "drug-able" targets that may improve leukemia therapy.

Credentials

Specialties

Pediatrics
Pediatric Hematology-Oncology - American Board of Pediatrics

Education

1984
PhD | University of Chicago, Pritzker School of Medicine

1986
MD | University of Chicago, Pritzker School of Medicine

Post-doctoral Training & Residency

07/01/1989 - 06/30/1992
Fellowship in Pediatric Hematology/Oncology at National Institute of Health

07/01/1987 - 06/30/1989
Residency in Pediatrics at Children's Medical Center of Dallas

07/01/1986 - 06/30/1987
Internship in Pediatrics at Children's Medical Center of Dallas

7/1/92 - 6/30/94
Research in Immunohematology at National Institute of Health

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Awards

2002
Award for Second International Symposium on Minor Histocompatibility Antigens
Sponsor: International Congress of Histocompatibility and Immunogenetics

1999
Dean's Excellence Award
Sponsor: Graduate School of Biomedical Sciences
Location: University of Texas-Houston Health Science Center

1992
American Association of Cancer Research
Sponsor: Upjohn Travel Award

1986
Alpha Omega Alpha

1986
Dr. Harold Lamport Biomedical Research Award (for the best PhD dissertation in biomedical research)
Location: University of Chicago

1978
Phi Beta Kappa

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Clinical Trials

A Randomized, Open-label, Active Controlled, Safety And Descriptive Efficacy Study In Pediatric Subjects Requiring Anticoagulation For The Treatment Of A Venous Thromboembolic Event

Lead Researcher: Craig A Mullen

To assess the safety and descriptive efficacy of apixaban in pediatric subjects requiring anticoagulation for the treatment of a VTE.

View Study Details

Publications

Journal Articles

6/2019
Usmani S, Sivagnanalingam U, Tkachenko O, Nunez L, Shand JC, Mullen CA. "Support of acute lymphoblastic leukemia cells by nonmalignant bone marrow stromal cells." Oncology letters.. 2019 Jun 0; 17(6):5039-5049. Epub 2019 Mar 22.

8/2018
Andolina JR, Reinish AL, Akhtar R, Noronha S, Shand JC, Girvin A, Korones DN, Bruckner LB, Mullen CA, Curran KJ, Boulad F. "Successful reduced-intensity conditioning hematopoietic stem cell transplantation for paroxysmal nocturnal hemoglobinuria with aplastic anemia in two children." Pediatric blood & cancer.. 2018 Aug 0; 65(8):e27218. Epub 2018 May 03.

2016
Pahl, K.; Mullen, C.A. "Acute chest syndrome in sickle cell disease: Effect of genotype and asthma" . Experimental Biology and Medicine. 2016; 241(7): 745-748.

Books & Chapters

2005
Chapter Title: Supportive Care in Pediatric Oncology: Part I
Book Title: Pediatric Oncology
Author List: Rodriguez N, Madden RM, Mullen CA
Edited By: Chan KW, Raney RB
Published By: Springer 2005 in New York, NY

2005
Chapter Title: Supportive Care in Pediatric Oncology: Part II
Book Title: Pediatric Oncology
Author List: Madden RM, Koontz-Webb S, Zhukovsky DS, Mullen CA
Edited By: Chan KW, Raney RB
Published By: Springer 2005 in New York, NY

1998
Chapter Title: Cytosine deaminase as a suicide gene in cancer gene therapy
Book Title: Gene Therapy of Cancer
Author List: Mullen CA
Edited By: Lattime N, Gerson G
Published By: Academic Press 1998 in San Diego, CA

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