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Andrew P. Wojtovich, Ph.D.

Publications

Showing all 31 journal articles & 0 books available

Journal Articles

9/20/2019
Trewin AJ, Bahr LL, Almast A, Berry BJ, Wei AY, Foster TH, Wojtovich AP. "Mitochondrial Reactive Oxygen Species Generated at the Complex-II Matrix or Intermembrane Space Microdomain Have Distinct Effects on Redox Signaling and Stress Sensitivity in ." Antioxidants & redox signaling.. 2019 Sep 20; 31(9):594-607. Epub 2019 Apr 22.

9/20/2019
Wojtovich AP, Berry BJ, Galkin A. "Redox Signaling Through Compartmentalization of Reactive Oxygen Species: Implications for Health and Disease." Antioxidants & redox signaling.. 2019 Sep 20; 31(9):591-593. Epub 2019 Jun 19.

8/8/2019
Philip NS, Escobedo F, Bahr LL, Berry BJ, Wojtovich AP. "Element-Mediated CRISPR Integration of Transgenes in ." G3 : genes - genomes - genetics.. 2019 Aug 8; 9(8):2629-2635. Epub 2019 Aug 08.

8/6/2019
Onukwufor JO, Berry BJ, Wojtovich AP. "Physiologic Implications of Reactive Oxygen Species Production by Mitochondrial Complex I Reverse Electron Transport." Antioxidants.. 2019 Aug 6; 8(8)Epub 2019 Aug 06.

11/20/2018
Trewin AJ, Berry BJ, Wei AY, Bahr LL, Foster TH, Wojtovich AP. "Light-induced oxidant production by fluorescent proteins." Free radical biology & medicine.. 2018 Nov 20; 128:157-164. Epub 2018 Feb 06.

10/19/2018
Berry BJ, Trewin AJ, Amitrano AM, Kim M, Wojtovich AP. "Use the Protonmotive Force: Mitochondrial Uncoupling and Reactive Oxygen Species." Journal of molecular biology.. 2018 Oct 19; 430(21):3873-3891. Epub 2018 Apr 04.

2/20/2018
Barnett ME, Baran TM, Foster TH, Wojtovich AP. "Quantification of light-induced miniSOG superoxide production using the selective marker, 2-hydroxyethidium." Free radical biology & medicine.. 2018 Feb 20; 116:134-140. Epub 2018 Jan 31.

1/6/2018
Trewin AJ, Berry BJ, Wojtovich AP. "Exercise and Mitochondrial Dynamics: Keeping in Shape with ROS and AMPK." Antioxidants.. 2018 Jan 6; 7(1)Epub 2018 Jan 06.

9/2016
Stoveken HM, Bahr LL, Anders MW, Wojtovich AP, Smrcka AV, Tall GG. "Dihydromunduletone Is a Small-Molecule Selective Adhesion G Protein-Coupled Receptor Antagonist." Molecular pharmacology.. 2016 Sep 0; 90(3):214-24. Epub 2016 Jun 23.

7/21/2016
Wojtovich AP, Wei AY, Sherman TA, Foster TH, Nehrke K. "Chromophore-Assisted Light Inactivation of Mitochondrial Electron Transport Chain Complex II in Caenorhabditis elegans." Scientific reports.. 2016 Jul 21; 6:29695. Epub 2016 Jul 21.

5/2016
Wojtovich AP, Smith CO, Urciuoli WR, Wang YT, Xia XM, Brookes PS, Nehrke K. "Cardiac Slo2.1 Is Required for Volatile Anesthetic Stimulation of K+ Transport and Anesthetic Preconditioning." Anesthesiology.. 2016 May 0; 124(5):1065-76.

6/2014
Raphemot R, Swale DR, Dadi PK, Jacobson DA, Cooper P, Wojtovich AP, Banerjee S, Nichols CG, Denton JS. "Direct activation of ?-cell KATP channels with a novel xanthine derivative." Molecular pharmacology.. 2014 Jun 0; 85(6):858-65. Epub 2014 Mar 19.

2014
Wojtovich AP, Foster TH. "Optogenetic control of ROS production." Redox biology.. 2014 2:368-76. Epub 2014 Feb 03.

6/1/2013
Wojtovich AP, Urciuoli WR, Chatterjee S, Fisher AB, Nehrke K, Brookes PS. "Kir6.2 is not the mitochondrial KATP channel but is required for cardioprotection by ischemic preconditioning." American journal of physiology. Heart and circulatory physiology.. 2013 Jun 1; 304(11):H1439-45. Epub 2013 Apr 12.

5/2013
Wojtovich AP, Smith CO, Haynes CM, Nehrke KW, Brookes PS. "Physiological consequences of complex II inhibition for aging, disease, and the mKATP channel." Biochimica et biophysica acta.. 2013 May 0; 1827(5):598-611. Epub 2013 Jan 02.

2013
Wojtovich AP, Nadtochiy SM, Urciuoli WR, Smith CO, Grunnet M, Nehrke K, Brookes PS. "A non-cardiomyocyte autonomous mechanism of cardioprotection involving the SLO1 BK channel." PeerJ.. 2013 1:e48. Epub 2013 Mar 05.

3/30/2012
Guo S, Olm-Shipman A, Walters A, Urciuoli WR, Devito S, Nadtochiy SM, Wojtovich AP, Brookes PS. "A cell-based phenotypic assay to identify cardioprotective agents." Circulation research.. 2012 Mar 30; 110(7):948-57. Epub 2012 Mar 06.

2/17/2012
Wojtovich AP, Distefano P, Sherman T, Brookes PS, Nehrke K. "Mitochondrial ATP-sensitive potassium channel activity and hypoxic preconditioning are independent of an inwardly rectifying potassium channel subunit in Caenorhabditis elegans." FEBS letters.. 2012 Feb 17; 586(4):428-34. Epub 2012 Jan 21.

1/2012
Wojtovich AP, Nadtochiy SM, Brookes PS, Nehrke K. "Ischemic preconditioning: the role of mitochondria and aging." Experimental gerontology.. 2012 Jan 0; 47(1):1-7. Epub 2011 Nov 10.

7/2011
Queliconi BB, Wojtovich AP, Nadtochiy SM, Kowaltowski AJ, Brookes PS. "Redox regulation of the mitochondrial K(ATP) channel in cardioprotection." Biochimica et biophysica acta.. 2011 Jul 0; 1813(7):1309-15. Epub 2010 Nov 20.

2011
Wojtovich AP, Sherman TA, Nadtochiy SM, Urciuoli WR, Brookes PS, Nehrke K. "SLO-2 is cytoprotective and contributes to mitochondrial potassium transport." PloS one.. 2011 6(12):e28287. Epub 2011 Dec 01.

11/15/2010
Gunter TE, Gerstner B, Lester T, Wojtovich AP, Malecki J, Swarts SG, Brookes PS, Gavin CE, Gunter KK. "An analysis of the effects of Mn2+ on oxidative phosphorylation in liver, brain, and heart mitochondria using state 3 oxidation rate assays." Toxicology and applied pharmacology.. 2010 Nov 15; 249(1):65-75. Epub 2010 Aug 26.

4/16/2010
Wojtovich AP, Williams DM, Karcz MK, Lopes CM, Gray DA, Nehrke KW, Brookes PS. "A novel mitochondrial K(ATP) channel assay." Circulation research.. 2010 Apr 16; 106(7):1190-6. Epub 2010 Feb 25.

3/2010
Gohil VM, Sheth SA, Nilsson R, Wojtovich AP, Lee JH, Perocchi F, Chen W, Clish CB, Ayata C, Brookes PS, Mootha VK. "Nutrient-sensitized screening for drugs that shift energy metabolism from mitochondrial respiration to glycolysis." Nature biotechnology.. 2010 Mar 0; 28(3):249-55. Epub 2010 Feb 14.

2/15/2010
Roser KS, Brookes PS, Wojtovich AP, Olson LP, Shojaie J, Parton RL, Anders MW. "Mitochondrial biotransformation of omega-(phenoxy)alkanoic acids, 3-(phenoxy)acrylic acids, and omega-(1-methyl-1H-imidazol-2-ylthio)alkanoic acids: a prodrug strategy for targeting cytoprotective antioxidants to mitochondria." Bioorganic & medicinal chemistry.. 2010 Feb 15; 18(4):1441-8. Epub 2010 Jan 15.

2010
Wojtovich AP, Nehrke KW, Brookes PS. "The mitochondrial complex II and ATP-sensitive potassium channel interaction: quantitation of the channel in heart mitochondria." Acta biochimica Polonica. 2010 57(4):431-4. Epub 2010 Nov 19.

11/6/2009
Miller CL, Oikawa M, Cai Y, Wojtovich AP, Nagel DJ, Xu X, Xu H, Florio V, Rybalkin SD, Beavo JA, Chen YF, Li JD, Blaxall BC, Abe JI, Yan C. "Role of Ca2+/calmodulin-stimulated cyclic nucleotide phosphodiesterase 1 in mediating cardiomyocyte hypertrophy." Circulation research.. 2009 Nov 6; 105(10):956-64. Epub 2009 Sep 24.

3/2009
Wojtovich AP, Brookes PS. "The complex II inhibitor atpenin A5 protects against cardiac ischemia-reperfusion injury via activation of mitochondrial KATP channels." Basic research in cardiology.. 2009 Mar 0; 104(2):121-9. Epub 2009 Feb 26.

11/21/2008
Wojtovich AP, Burwell LS, Sherman TA, Nehrke KW, Brookes PS. "The C. elegans mitochondrial K+(ATP) channel: a potential target for preconditioning." Biochemical and biophysical research communications.. 2008 Nov 21; 376(3):625-8. Epub 2008 Sep 20.

2008
Wojtovich AP, Brookes PS. "The endogenous mitochondrial complex II inhibitor malonate regulates mitochondrial ATP-sensitive potassium channels: implications for ischemic preconditioning." Biochimica et biophysica acta.. 2008 1777(7-8):882-9. Epub 2008 Apr 08.

3/2005
di Bernardo D, Thompson MJ, Gardner TS, Chobot SE, Eastwood EL, Wojtovich AP, Elliott SJ, Schaus SE, Collins JJ. "Chemogenomic profiling on a genome-wide scale using reverse-engineered gene networks." Nature biotechnology.. 2005 Mar 0; 23(3):377-83.