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Mahlon D. Johnson, M.D., Ph.D.

Contact Information

Phone Numbers

Office: (585) 275-3202

Fax: (585) 273-1027

URMFGA member of the University of Rochester Medical Faculty Group

groupAn Accountable Health Partner

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Research Labs

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Locations

University of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 626
Rochester, NY 14642

Faculty Appointments

Patient Care Setting

Pathology

Biography

Dr. Johnson has particular interest and expertise in neurosurgical pathology and neurodegenerative disorders. He has published extensively in peer-reviewed journals and numerous book chapters . He receives referrals for consultation from across the U.S.

Professional Background

Dr. Johnson did a residency in Anatomic Pathology, Fellowship in Neuropathology and Fellowship in Cell Biology at Vanderbilt Medical School. He was on the faculty at Vanderbilt for fifteen years becoming an Associate Professor with tenure, Director of Neuropathology and Director of the Neuropathology Training Program. He has been on the University of Rochester School of Medicine as a Professor of Neuropathology with tenure, Professor of Neurosurgery and Director of Neuropathology for over a decade. His diagnostic activities include neurosurgical and autopsy neuropathology, a consultation practice and as a consultant to the Monroe County Medical Examiner's Office. He also lectures at other medical schools. He has over 150 publications and is first author on over half.

Research

My lab studies leptomeningeal diseases especially meningeal neoplasia. Our emphasis in the past has been on identifying the role of growth factor/growth factor receptor expression and downstream signaling in the pathogenesis of meningiomas. This has included, for the first time, identifying expression and possible roles for the transforming growth factor beta superfamily, MEK-1- MAPK and PI3K-Akt pathways. We have also evaluated cerebrospinal effects on the leptomeningeal and meningioma cell proliferation. Additional studies have evaluated the expression and roles of mesothelin in the leptomeninges, metastases to the leptomeninges and in meningiomas.

Credentials

Education

1981
MD | University of Tennessee College of Medicine

1984
PhD | University of Tennessee College of Medicine

Post-doctoral Training & Residency

07/01/1989 - 06/30/1993
Research in Cell Biology at Vanderbilt University School of Medicine

07/01/1987 - 06/30/1989
Fellowship in Neuropathology at Vanderbilt University Medical Center

07/01/1985 - 06/30/1987
Residency in Pathology at Vanderbilt University Medical Center

09/01/1984 - 06/30/1985
Internship in Pathology at Vanderbilt University Medical Center

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Awards

2001
Pathology Residents Teaching Award, Anatomic Pathology

1984
Sigma Xi Excellence in Research Award

1982 - 1984
NIH National Research Service Award

1980
Alpha Omega Alpha Medical Honor Society

1976
NIH National Research Service Award

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Publications

Journal Articles

7/1/2021
Douglas CE, Haynie ML, Weinberg GA, Johnson MD, Bharadwaj R, Williams ZR. "Granulomatous Amoebic Encephalitis Mimicking Neuromyelitis Optica Spectrum Disorder." Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society.. 2021 Jul 1; Epub 2021 Jul 01.

1/20/2021
Khan IR, Gu Y, George BP, Malone L, Conway KS, Francois F, Donlon J, Quazi N, Reddi A, Ho CY, Herr DL, Johnson MD, Parikh GY. "Brain Histopathology of Adult Decedents after Extracorporeal Membrane Oxygenation." Neurology.. 2021 Jan 20; Epub 2021 Jan 20.

1/20/2021
Johnson MD. "Evaluation of fluid channels in the human dura and superior sagittal sinus in older patients." Neuroscience letters.. 2021 Jan 20; :135649. Epub 2021 Jan 20.

Books & Chapters

2017
Chapter Title: Meningeal Mass Lesions.
Book Title: Neuropthologic and Neuroradiologic Correlations: A Differential Diagnostic Text and Atlas.
Author List: Johnson MD, Hussain Ali.
Edited By: In Murat Goden, M Kumar
Published By: Cambridge Univ. Press 2017 in London, UK

2017
Chapter Title: Leptoeningeal and Dural lesions
Book Title: Neuropthologic and Neuroradiologic Correlations: A Differential Diagnostic Text and Atlas.
Author List: Hussain Ali., Johnson MD
Edited By: In Murat Godken, Manoti Kumar
Published By: Cambridge Univ. Press 2017 in London, UK

2009
Chapter Title: Muscle and nerve biopsy
Book Title: Modern Surgical Pathology
Author List: Atkinson J.A., Johnson M.D., Bouldin, T.W. and Whetsell W.O
Edited By: Noel Weider, Richard Cote, Saul Suster, and L Weiss
Published By: W.B. Saunders 2009 in New York

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