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Mahlon D. Johnson, M.D., Ph.D.


Contact Information

Phone Numbers

Office: (585) 276-3087

Fax: (585) 273-1027

URMFGA member of the University of Rochester Medical Faculty Group

groupAn Accountable Health Partner

assignmentAccepting New Patients

Faculty Appointments


Dr. Johnson has particular interest and expertise in neurosurgical pathology and neurodegenerative disorders. He has published extensively in peer-reviewed journals and receives referrals for consultation from across the U.S.

Professional Background

Dr. Johnson did a residency in Anatomic Pathology, Fellowship in Neuropathology and Fellowship in Cell Biology at Vanderbilt Medical School. He was on the faculty at Vanderbilt for twenty-five years becoming an Associate Professor with tenure, Director of Neuropathology and Director of the Neuropathology Training Program. He has been on the University of Rochester School of Medicine as a Professor of Neuropathology with tenure, Professor of Neurosurgery and Director of Neuropathology for over a decade. His diagnostic activities include neurosurgical and autopsy neuropathology, a consultation practice and as a consultant to the Monroe County Medical Examiner's.Office. He also lectures at other medical schools.


My lab studies leptomeningeal diseases especially meningeal neoplasia. Our emphasis in the past has been on identifying the role of growth factor/growth factor receptor expression and downstream signaling in the pathogenesis of meningiomas. This has included, for the first time, identifying expression and possible roles for the transforming growth factor beta superfamily, MEK-1- MAPK and PI3K-Akt pathways. We have also evaluated cerebrospinal effects on the leptomeningeal and meningioma cell proliferation. Additional studies have evaluated the expression and roles of mesothelin in the leptomeninges, metastases to the leptomeninges and in meningiomas.



  • Anatomic Pathology - American Board of Pathology
  • Neuropathology - American Board of Pathology


MD | University of Tennessee Health Science Center College of Medicine

PhD | University of Tennessee Health Science Center College of Medicine

Post-doctoral Training & Residency

07/01/1989 - 06/30/1993
Research in at Vanderbilt University School of Medicine

07/01/1987 - 06/30/1989
Fellowship in Neuropathology at Vanderbilt University Medical Center

09/01/1984 - 06/30/1987
Residency in Pathology at Vanderbilt University Medical Center

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Pathology Residents Teaching Award, Anatomic Pathology

Sigma Xi Excellence in Research Award

1982 - 1984
NIH National Research Service Award

Alpha Omega Alpha Medical Honor Society

NIH National Research Service Award

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Journal Articles

Nunno A, Johnson MD, Wu G, Li YM. "Metastatic prostate cancer mimicking a subdural hematoma: A case report and literature review." Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia.. 2018 Jul 4; Epub 2018 Jul 04.

Zimering JH, Stone JJ, Paulzak A, Markman JD, Johnson MD, Vates GE. "Ectopic brain tissue in the trigeminal nerve presenting as rapid-onset trigeminal neuralgia: case report." Journal of neurosurgery.. 2017 Dec 1; :1-4. Epub 2017 Dec 01.

Liu X, Mangla R, Tian W, Qiu X, Li D, Walter KA, Ekholm S, Johnson MD. "The preliminary radiogenomics association between MR perfusion imaging parameters and genomic biomarkers, and their predictive performance of overall survival in patients with glioblastoma." Journal of neuro-oncology.. 2017 Dec 0; 135(3):553-560. Epub 2017 Sep 09.

Books & Chapters

Chapter Title: Meningeal Mass Lesions.
Book Title: Neuropthologic and Neuroradiologic Correlations: A Differential Diagnostic Text and Atlas.
Author List: Johnson MD, Hussain Ali.
Edited By: In Murat Goden, M Kumar
Published By: Cambridge Univ. Press2017 in London, UK

Chapter Title: Leptoeningeal and Dural lesions
Book Title: Neuropthologic and Neuroradiologic Correlations: A Differential Diagnostic Text and Atlas.
Author List: Hussain Ali., Johnson MD
Edited By: In Murat Godken, Manoti Kumar
Published By: Cambridge Univ. Press2017 in London, UK

Chapter Title: Muscle and nerve biopsy
Book Title: Modern Surgical Pathology
Author List: Atkinson J.A., Johnson M.D., Bouldin, T.W. and Whetsell W.O
Edited By: Noel Weider, Richard Cote, Saul Suster, and L Weiss
Published By: W.B.Saunders2009 in New York