Mahlon D. Johnson, M.D., Ph.D.

Pathology

Contact Information

Phone Numbers

Office: (585) 276-3087

Fax: (585) 273-1027

A member of the University of Rochester Medical Faculty Group

An Accountable Health Partner

Accepting New Patients

Locations

University of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 626
Rochester, NY

Biography

Dr. Johnson has particular interest and expertise in neurosurgical pathology and neurodegenerative disorders. He has published extensively in peer-reviewed journals and receives referrals for consultation from across the U.S.

Professional Background

Dr. Johnson did a residency in Anatomic Pathology, Fellowship in Neuropathology and Fellowship in Cell Biology at Vanderbilt Medical School. He was on the faculty at Vanderbilt for twenty-five years becoming an Associate Professor with tenure, Director of Neuropathology and Director of the Neuropathology Training Program. He has been on the University of Rochester School of Medicine as a Professor of Neuropathology with tenure, Professor of Neurosurgery and Director of Neuropathology for over a decade. His diagnostic activities include neurosurgical and autopsy neuropathology, a consultation practice and as a consultant to the Monroe County Medical Examiner's.Office. He also lectures at other medical schools.

Research

My lab studies leptomeningeal diseases especially meningeal neoplasia. Our emphasis in the past has been on identifying the role of growth factor/growth factor receptor expression and downstream signaling in the pathogenesis of meningiomas. This has included, for the first time, identifying expression and possible roles for the transforming growth factor beta superfamily, MEK-1- MAPK and PI3K-Akt pathways. We have also evaluated cerebrospinal effects on the leptomeningeal and meningioma cell proliferation. Additional studies have evaluated the expression and roles of mesothelin in the leptomeninges, metastases to the leptomeninges and in meningiomas.

Credentials

Faculty Appointments

Professor - Department of Neurosurgery (SMD)
Director, Neuropathology - Department of Pathology and Laboratory Medicine (SMD)
Professor - Department of Pathology and Laboratory Medicine (SMD) - Primary

Specialties

Anatomic Pathology - American Board of Pathology
Neuropathology - American Board of Pathology

Education

1977
BA | Univ of Tennessee
Arts & Sciences

1981
MD | Univ Tennessee Coll Medicine
Medicine

1984
PhD | Univ Tennessee Coll Medicine
Pharmacology

Post-doctoral Training & Residency

09/01/1984 - 06/30/1987
Residency in Pathology-Anatomic and Clinical at Vanderbilt University Medical Center

07/01/1987 - 06/30/1989
Fellowship in Pathology-Anatomic and Clinical: Neuropathology at Vanderbilt University Medical Center

07/01/1989 - 06/30/1993
Research in at Vanderbilt University School of Medicine

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Awards

2001
Pathology Residents Teaching Award, Anatomic Pathology

1984
Sigma Xi Excellence in Research Award

1982 - 1984
NIH National Research Service Award

1980
Alpha Omega Alpha Medical Honor Society

1976
NIH National Research Service Award

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Publications

Journal Articles

8/2017
Johnson MD. "Transforming Growth Factor Beta Family in the Pathogenesis of Meningiomas." World neurosurgery.. 2017 Aug 0; 104:113-119. Epub 2017 Mar 23.

2017
Johnson MD, O'Connell M, Walter K. "STAT3 activation and risk of recurrence in meningiomas." Oncol Lett. 2017; 13: 2432-2436.

2017
Johnson MD, O'Connell M, Walter K, Silberstein H. "mTOR activation is increased in pilocytic astrocytomas from older adults compared with children." Surgical neurology international. 2017 8:85. Epub 2017 May 26.

Books & Chapters

2017
Chapter Title: Meningeal Mass Lesions.
Book Title: Neuropthologic and Neuroradiologic Correlations: A Differential Diagnostic Text and Atlas.
Author List: Johnson MD, Hussain Ali.
Edited By: In Murat Goden, M Kumar
Published By: Cambridge Univ. Press2017 in London, UK

2017
Chapter Title: Leptoeningeal and Dural lesions
Book Title: Neuropthologic and Neuroradiologic Correlations: A Differential Diagnostic Text and Atlas.
Author List: Hussain Ali., Johnson MD
Edited By: In Murat Godken, Manoti Kumar
Published By: Cambridge Univ. Press2017 in London, UK

2009
Chapter Title: Muscle and nerve biopsy
Book Title: Modern Surgical Pathology
Author List: Atkinson J.A., Johnson M.D., Bouldin, T.W. and Whetsell W.O
Edited By: Noel Weider, Richard Cote, Saul Suster, and L Weiss
Published By: W.B.Saunders2009 in New York

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