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Majed A. Refaai, M.D.

Contact Information

Phone Numbers

Office: (585) 276-3927

Fax: (585) 273-3003

URMFGA member of the University of Rochester Medical Faculty Group

groupAn Accountable Health Partner

assignmentAccepting New Patients

Faculty Appointments

Patient Care Setting

Pathology

Biography

Dr. Refaai's clinical service is in Transfusion Medicine with subspecialty involvement in laboratory coagulation/thrombosis testing.

Research

Dr. Refaai's recent studies have included: The in-vitro effect of ABO anti-bodies on platelet function; The correlation between cancer and tissue factor (TF) plasma concentrations and its role in developing DVT; The relationship between the circulating TF and the cancer tissue concentrations of TF in different types of mouse models; Beriplex phase IIIb drug study for bleeding patients with Warfarin overdose; Beriplex phase IIIb drug study for surgical patients who require a quick reversal of Warfarin; The effect of ABO non-identical blood products transfusion on platelet function (in-vivo); Platelet transfusion in patients with positive heparin-induced thrombocytopenia; Comparison of tissue factor pathway inhibitor (TFPI) concentration and activity in mononuclear cells from normal individuals versus patients with Paroxysmal Nocturnal Hemoglobinuria; Comparison of TFPI concentrations in normal mouse plasma and endothelial cells versus a diabetic mouse model; Analysis of fatty acid ethyl ester (FAEE) concentrations in binge drinking, chronic alcoholics, and postmortem biopsies.

Credentials

Specialties

  • Clinical Pathology/Laboratory Medicine - American Board of Pathology

Education

1993
MD | Aleppo University

Post-doctoral Training & Residency

07/01/2006 - 06/30/2007
Fellowship in Tranfusion Medicine at University of Texas Southwestern

06/30/2003 - 06/30/2006
Residency in Pathology at Barnes-Jewish Hospitals

04/01/1997 - 05/31/2003
Research at Massachusetts General Hospital

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Patents

Patent Title: Systemic and Topical Application of Platelet Microparticles to Treat Bleeding in Trauma Patients
Patent #: 3265116
Issue Date: Jun 02, 2021
Country: Europe
Invented By: Majed A Refaai

Patent Title: Systemic and Topical Application of Platelet Microparticles to Treat Bleeding in Trauma Patients
Patent #: FR3265116
Issue Date: Jun 02, 2021
Country: France
Invented By: Majed A Refaai

Patent Title: Systemic and Topical Application of Platelet Microparticles to Treat Bleeding in Trauma Patients
Patent #: DE3265116
Issue Date: Jun 02, 2021
Country: Germany
Invented By: Majed A Refaai

Patent Title: Systemic and Topical Application of Platelet Microparticles to Treat Bleeding in Trauma Patients
Patent #: GB3265116
Issue Date: Jun 02, 2021
Country: United Kingdom
Invented By: Majed A Refaai

Patent Title: Systemic and Topical Application of Platelet Microparticles to Treat Bleeding in Trauma Patients
Patent #: ZL 201680012653.9
Issue Date: Mar 19, 2021
Country: China, People's Republic of
Invented By: Majed A Refaai

Patent Title: Systemic and Topical Application of Platelet Microparticles to Treat Bleeding in Trauma Patients
Patent #: 10,722,608
Issue Date: Jul 28, 2020
Country: United States
Invented By: Majed A Refaai

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Publications

Journal Articles

12/27/2021
McRae HL, Milito C, Klapheke CA, Refaai MA. "Evaluation of solvent/detergent-treated plasma safety and efficacy in orthotopic liver transplant and thrombotic thrombocytopenic purpura patients: A single center experience." Transfusion.. 2021 Dec 27; Epub 2021 Dec 27.

12/7/2021
McRae HL, Millar MW, Slavin SA, Blumberg N, Rahman A, Refaai MA. "Essential Role of Rho-Associated Kinase in ABO Immune Complex-Mediated Endothelial Barrier Disruption." Biomedicines.. 2021 Dec 7; 9(12)Epub 2021 Dec 07.

10/2021
Refaai MA, Jacobson AK, Rosenfeld JC, Orr RR. "Performance of the microINR Point-of-Care System Used by Self-Testing Patients: A Multicenter Clinical Trial." . 2021 Oct 0; 5(4):e577-e584. Epub 2021 Dec 30.

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