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Majed A. Refaai, M.D.

Pathology

Contact Information

Phone Numbers

Office: (585) 276-3927

Fax: (585) 273-3003

URMFGA member of the University of Rochester Medical Faculty Group

groupAn Accountable Health Partner

assignmentAccepting New Patients

Biography

Dr. Refaai's clinical service is in Transfusion Medicine with subspecialty involvement in laboratory coagulation/thrombosis testing.

Research

Dr. Refaai's recent studies have included: The in-vitro effect of ABO anti-bodies on platelet function; The correlation between cancer and tissue factor (TF) plasma concentrations and its role in developing DVT; The relationship between the circulating TF and the cancer tissue concentrations of TF in different types of mouse models; Beriplex phase IIIb drug study for bleeding patients with Warfarin overdose; Beriplex phase IIIb drug study for surgical patients who require a quick reversal of Warfarin; The effect of ABO non-identical blood products transfusion on platelet function (in-vivo); Platelet transfusion in patients with positive heparin-induced thrombocytopenia; Comparison of tissue factor pathway inhibitor (TFPI) concentration and activity in mononuclear cells from normal individuals versus patients with Paroxysmal Nocturnal Hemoglobinuria; Comparison of TFPI concentrations in normal mouse plasma and endothelial cells versus a diabetic mouse model; Analysis of fatty acid ethyl ester (FAEE) concentrations in binge drinking, chronic alcoholics, and postmortem biopsies.

Credentials

Faculty Appointments

Specialties

  • Clinical Pathology/Laboratory Medicine - American Board of Pathology

Education

1993
MD | Syria - Aleppo Univ School of Medicine, Aleppo
Medicine

Post-doctoral Training & Residency

04/01/1997 - 05/31/2003
Research in at Massachusetts General Hospital

06/30/2003 - 06/30/2006
Residency in Pathology-Anatomic and Clinical at Barnes-Jewish Hospitals

07/01/2006 - 06/30/2007
Fellowship in Transfusion Medicine at University of Texas Southwestern

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Publications

Journal Articles

7/10/2017
Cahill CM, Blumberg N, Schmidt AE, Knight PA, Melvin AL, Massey HT, Delehanty JM, Zebrak SB, Refaai MA. "Implementation of a Standardized Transfusion Protocol for Cardiac Patients Treated With Venoarterial Extracorporeal Membrane Oxygenation Is Associated With Decreased Blood Component Utilization and May Improve Clinical Outcome." Anesthesia and analgesia.. 2017 Jul 10; Epub 2017 Jul 10.

6/2017
Farnsworth CW, Schott EM, Jensen SE, Zukoski J, Benvie AM, Refaai MA, Kates SL, Schwarz EM, Zuscik MJ, Gill SR, Mooney RA. "Adaptive Upregulation of Clumping Factor A (ClfA) by Staphylococcus aureus in the Obese, Type 2 Diabetic Host Mediates Increased Virulence." Infection and immunity.. 2017 Jun 0; 85(6)Epub 2017 May 23.

5/4/2017
Blumberg N, Cholette JM, Schmidt AE, Phipps RP, Spinelli SL, Heal JM, Pietropaoli AP, Refaai MA, Sime PJ. "Management of Platelet Disorders and Platelet Transfusions in ICU Patients." Transfusion medicine reviews.. 2017 May 4; Epub 2017 May 04.

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