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Majed A. Refaai, M.D.

Contact Information

Phone Numbers

Office: (585) 276-3927

Fax: (585) 273-3003

URMFGA member of the University of Rochester Medical Faculty Group

groupAn Accountable Health Partner

assignmentAccepting New Patients

Faculty Appointments

Patient Care Setting



Dr. Refaai's clinical service is in Transfusion Medicine with subspecialty involvement in laboratory coagulation/thrombosis testing.


Dr. Refaai's recent studies have included: The in-vitro effect of ABO anti-bodies on platelet function; The correlation between cancer and tissue factor (TF) plasma concentrations and its role in developing DVT; The relationship between the circulating TF and the cancer tissue concentrations of TF in different types of mouse models; Beriplex phase IIIb drug study for bleeding patients with Warfarin overdose; Beriplex phase IIIb drug study for surgical patients who require a quick reversal of Warfarin; The effect of ABO non-identical blood products transfusion on platelet function (in-vivo); Platelet transfusion in patients with positive heparin-induced thrombocytopenia; Comparison of tissue factor pathway inhibitor (TFPI) concentration and activity in mononuclear cells from normal individuals versus patients with Paroxysmal Nocturnal Hemoglobinuria; Comparison of TFPI concentrations in normal mouse plasma and endothelial cells versus a diabetic mouse model; Analysis of fatty acid ethyl ester (FAEE) concentrations in binge drinking, chronic alcoholics, and postmortem biopsies.



  • Clinical Pathology/Laboratory Medicine - American Board of Pathology


MD | Aleppo University

Post-doctoral Training & Residency

07/01/2006 - 06/30/2007
Fellowship in Tranfusion Medicine at University of Texas Southwestern

06/30/2003 - 06/30/2006
Residency in Pathology at Barnes-Jewish Hospitals

04/01/1997 - 05/31/2003
Research in at Massachusetts General Hospital

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Patent Title: Systemic and Topical Application of Platelet Microparticles to Treat Bleeding in Trauma Patients
Patent #: 10,722,608
Issue Date: Jul 28, 2020
Country: United States
Invented By: Majed A Refaai


Journal Articles

McRae HL, Yang AH, Kruzer K, Scott GA, Refaai MA. "A Rare Case of Catastrophic Antiphospholipid Syndrome Triggered by Estrogen-Containing Oral Contraceptives in a Patient with Double Heterozygous Factor V Leiden and Prothrombin G20210A Mutations." American journal of hematology.. 2021 Feb 23; Epub 2021 Feb 23.

Milling TJ, Refaai MA, Sengupta N. "Anticoagulant Reversal in Gastrointestinal Bleeding: Review of Treatment Guidelines." Digestive diseases and sciences.. 2021 Jan 6; Epub 2021 Jan 06.

Turgeman A, McRae HL, Cahill C, Blumberg N, Refaai MA. "Impact of RBC Transfusion on Peripheral Capillary Oxygen Saturation and Partial Pressure of Arterial Oxygen." American journal of clinical pathology.. 2020 Dec 21; Epub 2020 Dec 21.