Joseph C. Holt, Ph.D.

Joseph C. Holt, Ph.D.

Contact Information

University of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 629
Rochester, NY 14642

Office: (585) 273-3064
Lab: (585) 276-2703

Journal Articles

Showing all 17 journal articles available.

2016 Jul
Dickerson IM, Bussey-Gaborski R, Holt JC, Jordan PM, Luebke AE. "Maturation of suprathreshold auditory nerve activity involves cochlear CGRP-receptor complex formation." Physiological reports. 2016 Jul; 4(14)
2015 Jun 1
Jordan PM, Fettis M, Holt JC. "Efferent innervation of turtle semicircular canal cristae: comparisons with bird and mouse." The Journal of comparative neurology. 2015 Jun 1; 523(8):1258-80. Epub 2015 Mar 25.
2015 Feb 25
Holt JC, Kewin K, Jordan PM, Cameron P, Klapczynski M, McIntosh JM, Crooks PA, Dwoskin LP, Lysakowski A. "Pharmacologically distinct nicotinic acetylcholine receptors drive efferent-mediated excitation in calyx-bearing vestibular afferents." The Journal of neuroscience : the official journal of the Society for Neuroscience. 2015 Feb 25; 35(8):3625-43.
2014 Jul 30
Luebke AE, Holt JC, Jordan PM, Wong YS, Caldwell JS, Cullen KE. "Loss of ?-calcitonin gene-related peptide (?CGRP) reduces the efficacy of the Vestibulo-ocular Reflex (VOR)." The Journal of neuroscience : the official journal of the Society for Neuroscience. 2014 Jul 30; 34(31):10453-8.
Jordan PM, Parks XX, Contini D, Holt JC. "A review of synaptic mechanisms of vestibular efferent signaling in turtles: extrapolation to efferent actions in mammals." Journal of vestibular research : equilibrium & orientation. 2013 23(3):161-75.
2007 Sep
Holt JC, Chatlani S, Lysakowski A, Goldberg JM. "Quantal and nonquantal transmission in calyx-bearing fibers of the turtle posterior crista." Journal of neurophysiology. 2007 Sep; 98(3):1083-101. Epub 2007 Jun 27.
2006 Dec 20
Holt JC, Lysakowski A, Goldberg JM. "Mechanisms of efferent-mediated responses in the turtle posterior crista." The Journal of neuroscience : the official journal of the Society for Neuroscience. 2006 Dec 20; 26(51):13180-93.
2006 Jan
Holt JC, Xue JT, Brichta AM, Goldberg JM. "Transmission between type II hair cells and bouton afferents in the turtle posterior crista." Journal of neurophysiology. 2006 Jan; 95(1):428-52. Epub 2005 Sep 21.
2003 Sep
Holt JC, Lioudyno M, Guth PS. "A pharmacologically distinct nicotinic ACh receptor is found in a subset of frog semicircular canal hair cells." Journal of neurophysiology. 2003 Sep; 90(3):1526-36.
2002 Aug
Lioudyno MI, Verbitsky M, Glowatzki E, Holt JC, Boulter J, Zadina JE, Elgoyhen AB, Guth PS. "The alpha9/alpha10-containing nicotinic ACh receptor is directly modulated by opioid peptides, endomorphin-1, and dynorphin B, proposed efferent cotransmitters in the inner ear." Molecular and cellular neurosciences. 2002 Aug; 20(4):695-711.
2001 Feb
Holt JC, Lioudyno M, Athas G, Garcia MM, Perin P, Guth PS. "The effect of proteolytic enzymes on the alpha9-nicotinic receptor-mediated response in isolated frog vestibular hair cells." Hearing research. 2001 Feb; 152(1-2):25-42.
2000 Nov
Lioudyno MI, Verbitsky M, Holt JC, Elgoyhen AB, Guth PS. "Morphine inhibits an alpha9-acetylcholine nicotinic receptor-mediated response by a mechanism which does not involve opioid receptors." Hearing research. 2000 Nov; 149(1-2):167-77.
2000 Aug
Holt JC, Pantoja AM, Athas GB, Guth PS. "A role for chloride in the hyperpolarizing effect of acetylcholine in isolated frog vestibular hair cells." Hearing research. 2000 Aug; 146(1-2):17-27.
1998 Nov
Guth PS, Holt JC, Perin P, Athas G, Garcia M, Puri A, Zucca G, Botta L, Valli P. "The metabotropic glutamate receptors of the vestibular organs." Hearing research. 1998 Nov; 125(1-2):154-62.
1998 Sep
Norris CH, Miller AJ, Perin P, Holt JC, Guth PS. "Mechanisms and effects of transepithelial polarization in the isolated semicircular canal." Hearing research. 1998 Sep; 123(1-2):31-40.
1997 Oct
Pantoja AM, Holt JC, Guth PS. "A role for chloride in the suppressive effect of acetylcholine on afferent vestibular activity." Hearing research. 1997 Oct; 112(1-2):21-32.
1996 Feb
Michel RE, Holt JC, Domer FR. "Ketorolac causes the release of methionine-enkephalin in rats." Research communications in molecular pathology and pharmacology. 1996 Feb; 91(2):249-52.


Holt JC: Lysakowski A: Goldberg JM. "Vestibular Efferents". Handbook of Auditory Research: Auditory and Vestibular Efferents. Ryugo DK, Fay RR, Popper AN. : Springer, 2011.