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Angela Glading, Ph.D.

Publications

Showing all 24 journal articles & 0 books available

Journal Articles

12/21/2020
De Luca E, Perrelli A, Swamy H, Nitti M, Passalacqua M, Furfaro AL, Salzano AM, Scaloni A, Glading AJ, Retta SF. "Protein kinase C? (PKC?) regulates the nucleocytoplasmic shuttling of KRIT1." Journal of cell science.. 2020 Dec 21; Epub 2020 Dec 21.

4/2020
Khire TS, Salminen AT, Swamy H, Lucas KS, McCloskey MC, Ajalik RE, Chung HH, Gaborski TR, Waugh RE, Glading AJ, McGrath JL. "Microvascular Mimetics for the Study of Leukocyte-Endothelial Interactions." Cellular and molecular bioengineering.. 2020 Apr; 13(2):125-139. Epub 2020 Jan 31.

1/2020
DiStefano PV, Glading AJ. "VEGF signalling enhances lesion burden in KRIT1 deficient mice." Journal of cellular and molecular medicine.. 2020 Jan; 24(1):632-639. Epub 2019 Nov 20.

2020
Nobiletti N, Glading AJ. "Isolation of Cerebral Endothelial Cells from CCM1/KRIT1 Null Mouse Brain." Methods in molecular biology.. 2020 2152:259-265.

2020
Glading AJ. "Measurement of Endothelial Barrier Function in Mouse Models of Cerebral Cavernous Malformations Using Intravital Microscopy." Methods in molecular biology.. 2020 2152:387-400.

8/15/2017
Goitre L, DiStefano PV, Moglia A, Nobiletti N, Baldini E, Trabalzini L, Keubel J, Trapani E, Shuvaev VV, Muzykantov VR, Sarelius IH, Retta SF, Glading AJ. "Up-regulation of NADPH oxidase-mediated redox signaling contributes to the loss of barrier function in KRIT1 deficient endothelium." Scientific reports.. 2017 Aug 15; 7(1):8296. Epub 2017 Aug 15.

12/2016
Retta SF, Glading AJ. "Oxidative stress and inflammation in cerebral cavernous malformation disease pathogenesis: Two sides of the same coin." The international journal of biochemistry & cell biology.. 2016 Dec; 81(Pt B):254-270. Epub 2016 Sep 14.

2016
DiStefano PV, Smrcka AV, Glading AJ. "Phospholipase C? Modulates Rap1 Activity and the Endothelial Barrier." PloS one.. 2016 11(9):e0162338. Epub 2016 Sep 09.

2015
Sarelius IH, Glading AJ. "Control of vascular permeability by adhesion molecules." Tissue barriers. 2015 3(1-2):e985954. Epub 2015 Apr 03.

11/21/2014
Distefano PV, Kuebel JM, Sarelius IH, Glading AJ. "KRIT1 protein depletion modifies endothelial cell behavior via increased vascular endothelial growth factor (VEGF) signaling." The Journal of biological chemistry.. 2014 Nov 21; 289(47):33054-65. Epub 2014 Oct 15.

11/2012
Corr M, Lerman I, Keubel JM, Ronacher L, Misra R, Lund F, Sarelius IH, Glading AJ. "Decreased Krev interaction-trapped 1 expression leads to increased vascular permeability and modifies inflammatory responses in vivo." Arteriosclerosis, thrombosis, and vascular biology.. 2012 Nov; 32(11):2702-10. Epub 2012 Aug 23.

2010
Glading AJ, Ginsberg MH. "Rap1 and its effector KRIT1/CCM1 regulate beta-catenin signaling." Disease models & mechanisms.. 2010 3(1-2):73-83. Epub 2009 Dec 09.

10/22/2007
Glading A, Han J, Stockton RA, Ginsberg MH. "KRIT-1/CCM1 is a Rap1 effector that regulates endothelial cell cell junctions." The Journal of cell biology.. 2007 Oct 22; 179(2):247-54.

2/15/2007
Glading A, Koziol JA, Krueger J, Ginsberg MH. "PEA-15 inhibits tumor cell invasion by binding to extracellular signal-regulated kinase 1/2." Cancer research.. 2007 Feb 15; 67(4):1536-44.

8/2005
Krueger J, Chou FL, Glading A, Schaefer E, Ginsberg MH. "Phosphorylation of phosphoprotein enriched in astrocytes (PEA-15) regulates extracellular signal-regulated kinase-dependent transcription and cell proliferation." Molecular biology of the cell.. 2005 Aug; 16(8):3552-61. Epub 2005 May 25.

3/2005
Satish L, Blair HC, Glading A, Wells A. "Interferon-inducible protein 9 (CXCL11)-induced cell motility in keratinocytes requires calcium flux-dependent activation of mu-calpain." Molecular and cellular biology.. 2005 Mar; 25(5):1922-41.

3/2004
Glading A, Bodnar RJ, Reynolds IJ, Shiraha H, Satish L, Potter DA, Blair HC, Wells A. "Epidermal growth factor activates m-calpain (calpain II), at least in part, by extracellular signal-regulated kinase-mediated phosphorylation." Molecular and cellular biology.. 2004 Mar; 24(6):2499-512.

12/26/2003
Chou FL, Hill JM, Hsieh JC, Pouyssegur J, Brunet A, Glading A, Uberall F, Ramos JW, Werner MH, Ginsberg MH. "PEA-15 binding to ERK1/2 MAPKs is required for its modulation of integrin activation." The Journal of biological chemistry.. 2003 Dec 26; 278(52):52587-97. Epub 2003 Sep 23.

4/2002
Shiraha H, Glading A, Chou J, Jia Z, Wells A. "Activation of m-calpain (calpain II) by epidermal growth factor is limited by protein kinase A phosphorylation of m-calpain." Molecular and cellular biology.. 2002 Apr; 22(8):2716-27.

1/2002
Glading A, Lauffenburger DA, Wells A. "Cutting to the chase: calpain proteases in cell motility." Trends in cell biology. 2002 Jan; 12(1):46-54.

6/29/2001
Glading A, Uberall F, Keyse SM, Lauffenburger DA, Wells A. "Membrane proximal ERK signaling is required for M-calpain activation downstream of epidermal growth factor receptor signaling." The Journal of biological chemistry.. 2001 Jun 29; 276(26):23341-8. Epub 2001 Apr 23.

1/28/2000
Glading A, Chang P, Lauffenburger DA, Wells A. "Epidermal growth factor receptor activation of calpain is required for fibroblast motility and occurs via an ERK/MAP kinase signaling pathway." The Journal of biological chemistry.. 2000 Jan 28; 275(4):2390-8.

7/12/1999
Shiraha H, Glading A, Gupta K, Wells A. "IP-10 inhibits epidermal growth factor-induced motility by decreasing epidermal growth factor receptor-mediated calpain activity." The Journal of cell biology.. 1999 Jul 12; 146(1):243-54.

12/1/1998
Wells A, Gupta K, Chang P, Swindle S, Glading A, Shiraha H. "Epidermal growth factor receptor-mediated motility in fibroblasts." Microscopy research and technique.. 1998 Dec 1; 43(5):395-411.