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Jeffrey R. Andolina, M.D., M.S.

Contact Information

Phone Numbers

Appointment: (585) 275-2981

Administrative: (585) 275-2981

Office: (585) 275-2981

Fax: (585) 273-1039

URMFGA member of the University of Rochester Medical Faculty Group

groupAn Accountable Health Partner

assignmentAccepting New Patients

Faculty Appointments

Patient Care Settings

Cancer, Pediatrics

Biography

Dr. Andolina is most interested in the treatment and comprehensive care for children with leukemia and lymphoma, including acute lymphoblastic leukemia (ALL), acute myeloid leukemia (AML), and chronic myeloid leukemia (CML), as well as the care for children with other cancers and blood diseases.

Dr. Andolina is the Director of Pediatric Bone Marrow Transplantation and has experience in treating both Leukemias, as well as non-malignant conditions including aplastic anemia and Immunodeficiencies. He has a particular interest in bone marrow transplant for patients with sickle cell anemia. In addition, Dr. Andolina has an interest in the adolescent and young adult population; he also cares for young adults undergoing bone marrow transplantation.

The University of Rochester is a member of multiple cooperative groups for pediatric cancer and pediatric bone marrow transplantation, including the Children's Oncology Group (COG), the Pediatric Blood and Marrow Tissue Consortium (PBMTC), and the Primary Immune Deficiency Treatment Consortium (PIDTC). Dr. Andolina is an investigator with each of these national groups and is the primary investigator for the PBMTC and PIDTC. He is on both the CML disease committee and also the cellular therapy committee of the COG. Together, we have over 75 clinical trials open and strive to have all front-line treatment studies open for our pediatric and young adult patients.

Please contact Dr. Andolina directly with any patient related or clinical related questions or concerns.

jeffrey_andolina@urmc.rochester.edu

Professional Background

Associate Professor of Pediatrics
Pediatric Hematology/Oncology/Stem Cell Transplantation
Director, Pediatric Bone Marrow Transplantation

Research

Dr. Andolina is interested in improving the outcome for children with cancer through offering enrollment on multi-institutional clinical trials through the Children's Oncology Group (COG) and Pediatric Blood and Marrow Tissue Consortium (PBMTC).

Dr. Andolina has a particular interest in Pediatric Bone Marrow Transplantation; Leukemia; Lymphoma; Neuroblastoma; Hematology, Oncology; Pediatric Hematology Oncology; Pediatric Oncology; Pediatric Cancer.

Dr. Andolina's research interests including improving bone marrow transplantation for children and young adults. He and colleagues have developed a clinical trial using haploidentical donors for bone marrow transplant, for those patients without fully matched sibling or matched unrelated donors. Haploidentical donors are "half matches," and almost all patients will have an available haploidentical donor, as all biological parents and half of full siblings will fall into this category.

Other research interests include evaluating reduced-intensity conditioning regimens for pediatric patients with malignant and non-malignant diseases, especially sickle cell anemia.

Dr. Andolina also performs laboratory research including the study of the gene expression profile of acute lymphoblastic leukemia cells, specifically evaluating gene expression changes which may confer survival advantages post-allogeneic hematopoietic stem cell transplantation.

Please contact Dr. Andolina directly with any patient related or clinical related questions or concerns.

jeffrey_andolina@urmc.rochester.edu

Credentials

Specialties

  • Pediatrics
  • Pediatric Hematology-Oncology - American Board of Pediatrics

Education

2004
MD | University of Virginia School of Medicine

Post-doctoral Training & Residency

07/01/2007 - 06/30/2010
Fellowship in Pediatric Hematology/Oncology at Children's Memorial Hospital, Northwestern University

06/21/2005 - 06/30/2007
Residency in Pediatrics at Children's Memorial Hospital, Northwestern University

06/21/2004 - 06/20/2005
Internship in Pediatrics at Children's Memorial Hospital, Northwestern University

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Awards

2020 - 2020
Faculty Teaching Award for Pediatrics, presented by medical student class of 2021
Sponsor: University of Rochester

2017 - 2018
Faculty Teaching Award for Pediatrics, presented by medical student class of 2019
Sponsor: Pediatric and Medicine-Pediatric Residents Class of 2018
Location: University of Rochester Medical Center

2017 - 2017
Early Career Distinguished Service Award
Sponsor: The Rochester Academy of Medicine
Location: Rochester, New York

2016 - 2016
Young Investigator Award, travel stipend
Sponsor: Pediatric Blood and Marrow Tissue Consortium (PBMTC)

2015 - 2016
Faculty Teaching Award
Sponsor: Pediatric and Medicine-Pediatric Residents Class of 2016
Location: University of Rochester Medical Center

2015 - 2016
Ruth A. Lawrence Academic Faculty Service Award
Location: University of Rochester Medical Center

2015 - 2015
ICare Bronze Star Award
Sponsor: University of Rochester Medical Center
Location: Rochester, New York

2014 - 2015
Faculty Teaching Award for Pediatrics presented by UR Medicine Medical Student Class of 2016
Sponsor: University of Rochester Medical Center
Location: Rochester, New York

2013 - 2014
Alpha Omega Alpha (AOA)
Sponsor: University of Rochester Medical Center
Location: Inducted into AOA by Medical Student Class of 2013

2013 - 2014
Faculty Teaching Award for Pediatrics
Sponsor: Medical Student Class of 2013
Location: University of Rochester Medical Center

2012 - Present
Children's Oncology Group Primary Investigator (PI)
Sponsor: University of Rochester Medical Center
Location: Rochester, New York

2007
A. Todd Davis Physician Award
Location: Children's Memorial Hospital

2007
Resident Teaching Award
Location: Children's Memorial Hospital, Chicago, IL

2005
Resident Teaching Award
Location: Children's Memorial Hospital, Chicago, IL

2004
Gold Humanism in Medicine Honor Society
Location: University of Virginia School of Medicine

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Clinical Trials

A phase II pilot trial to estimate survival after a non-total body irradiation (TBI) based conditioning regimen in patients diagnosed with B-acute lymphoblastic leukemia (ALL) who are pre-allogeneic hematopoietic cell transplantation (HCT) next-generation-sequence (NGS) minimal residual disease (MRD) negative

Lead Researcher: Jeffrey R Andolina

This study will evaluate the use of non- TBI (total body irradiation) conditioning for B-ALL patients with low risk of relapse as defined by the lack of residual disease (NGS-MRD before receiving a hematopoietic cell transplant (HCT). Patients diagnosed with B-ALL who are candidates for a transplant will be screened on a test of bone marrow done before the transplant.

View Study Details

Haploidentical Donor Hematopoietic Stem Cell Transplantation

Lead Researcher: Jeffrey R Andolina

This study will be a single-center treatment protocol with five possible preparative regimens, designed to validate the process of related donor haploidentical stem cell transplantation at the Wilmot Cancer Institute Blood and Marrow Transplant Unit. Enrolled patients will receive chemotherapy +/- radiation as a pre-transplant conditioning regimen. Patients will then receive haploidentical stem cells, either bone marrow or mobilized peripheral blood, followed by GvHD prophylaxis that will include cyclophosphamide. Multiple data points will be collected prior to, during, and following transplantation to ensure safety of the process and to evaluate the stated objectives.

View Study Details

Publications

Journal Articles

5/2020
Andolina JR, Walia R, Oliva J, Baran A, Liesveld J, Becker MW, Busacco A, Coppage M. "Non-donor specific anti-human leukocyte antigen (HLA) antibodies are not associated with poor outcome in hematopoietic stem cell transplant recipients." Hum Immunol. 2020; S0198-8859(20): 30318-9.

2020
Andolina JR. "StALKing Histiocytosis: ALK-positive histiocytosis identified through peripheral blood smear (in press)" . Acta Haematol. 2020; .

2020
Chan AY, Leiding JW, Liu X, Logan BR, Burroughs LM, Allenspach EJ, Skoda-Smith S, Uzel G, Notarangelo LD, Slatter M, Gennery AR, Smith AR, Pai SY, Jordan MB, Marsh RA, Cowan MJ, Dvorak CC, Craddock JA, Prockop SE, Chandrakasan S, Kapoor N, Buckley RH, Parikh S, Chellapandian D, Oshrine BR, Bednarski JJ, Cooper MA, Shenoy S, Davila Saldana BJ, Forbes LR, Martinez C, Haddad E, Shyr DC, Chen K, Sullivan KE, Heimall J, Wright N, Bhatia M, Cuvelier GDE, Goldman FD, Meyts I, Miller HK, Seidel MG, Vander Lugt MT, Bacchetta R, Weinacht KG, Andolina JR, Caywood E, Chong H, de la Morena MT, Aquino VM, Shereck E, Walter JE, Dorsey MJ, Seroogy CM, Griffith LM, Kohn DB, Puck JM, Pulsipher MA, Torgerson TR. "Hematopoietic Cell Transplantation in Patients With Primary Immune Regulatory Disorders (PIRD): A Primary Immune Deficiency Treatment Consortium (PIDTC) Survey." Frontiers in immunology.. 2020 11:239. Epub 2020 Feb 21.

Books & Chapters

2019
Chapter Title: Solid Tumors and Leukemias
Book Title: Avery's Neonatology Board Review
Author List: Andolina, JR
Published By: Elsevier 2019

2019
Chapter Title: White Blood Cells
Book Title: Avery's Neonatology Board Review
Author List: Andolina, JR
Published By: Elsevier 2019

2019
Chapter Title: Transfusion Therapy in Neonates
Book Title: Avery's Neonatology Board Review
Author List: Andolina, JR
Published By: Elsevier 2019

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