Biography
Dr. Sonal Munsiff is board-certified in Infectious Diseases. She manages many acute and chronic infections mostly in the outpatient clinic setting, with particular interest in bone and joint infections, orthopedic hardware, and cardiac device related infections, infections with drug resistant organism, HIV, and mycobacterial infections. She is working with a multidisciplinary staff to manage Outpatient IV antibiotics patients for the institution.
Professional Background
Dr. Sonal Munsiff is board-certified in Infectious Diseases. She manages many acute and chronic infections mostly in the outpatient clinic setting, with particular interest in bone and joint infections, orthopedic hardware, and device related infections, infections with drug resistant organism, HIV and AIDS, and mycobacterial infections. She is working with a multidisciplinary staff to manage Outpatient IV antibiotic patients for the institution. She will be teaching "Epidemiology of Infectious Disease" Course in the Epidemiology Division of the School of Medicine and Dentistry in Fall 2017.
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Previously she has worked in the field of TB control for 15 years with the NYC Bureau of Tuberculosis Control, and with CDC. She served as the Director of Epidemiology for the Program for several years, and then was Director and Assistant Commissioner of the program for 7 years. She has conducted research on various aspects of TB, particularly drug-resistant TB, complications and treatment of TB in HIV-infected persons, transmission and molecular epidemiology of TB, outbreak investigations, and program evaluation. She was co-investigator for the CDC TB clinical rails Unit on studying Moxifloxacin for TB treatment. She has authored over 60 medical publications, including the NYC "TB manual".
Research
Dr. Munsiff's current research interests include optimal diagnosis and management of osteomyelitis, usefulness of the Interferon gamma release assays for diagnosis of latent TB infection, and diagnosis and management of non tuberculous mycobacterial diseases.
Previously she has worked in the field of TB control for 15 years and has conducted research on various aspects of TB, particularly drug-resistant TB, complications and treatment of TB in HIV-infected persons, transmission and molecular epidemiology of TB, outbreak investigations, and program evaluation. She was co-investigator for the CDC TB clinical rails Unit on studying Moxifloxacin for TB treatment. She has authored over 60 medical publications, including the NYC "TB manual".
Clinical Trials
A5418 A Randomized, Placebo-Controlled, Double-Blinded Trial of the Safety and Efficacy of Tecovirimat for the Treatment of Human Monkeypox Virus Disease
Lead Researcher: Sonal Munsiff
This study will determine if the drug, tecovirimat, helps treat people you are infected with monkeypox virus.
You must be 18 years of age or older to participate. You must have a positive laboratory test for monkeypox virus within 14 days of enrolling in the study and at least one skin lesion. Participants with severe disease, significant skin conditions, participants with severe immune suppression will receive open-label tecovirimat. Participants who are pregnant or breastfeeding will receive open-label tecovirimat after discussion of the potential risks and benefits. Participants less than 18 years of age will receive open-label tecovirimat. Participants receiving a potent inducing concomitant medication will receive open-label tecovirimat.
Once enrolled, study drug administration will be for 14 days.
Participants will self-monitor skin and/or mucosal lesions daily through 29 days or resolution (whichever comes first), complete a daily diary of symptoms and complete a daily numerical rating scale for pain assessment.
Participants will be seen weekly through day 29 for assessment of HMPXV disease, safety assessments, HMPXV sampling similar to that described for entry, and swabbing of new HMPXV lesions.
Participants will be seen at day 57 to assess for possible recrudescence of infection (i.e., new lesions occurring after initial resolution of disease.
View Study Details
Publications
Journal Articles
3/16/2022
Munsiff S, Louie T. "Prosthetic Joint Infections and Rifampin." Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.. 2022 Mar 16; Epub 2022 Mar 16.
1/25/2022
Sridhar S, Joaquin A, Bonaparte MI, Bueso A, Chabanon AL, Chen A, Chicz RM, Diemert D, Essink BJ, Fu B, Grunenberg NA, Janosczyk H, Keefer MC, Rivera M DM, Meng Y, Michael NL, Munsiff SS, Ogbuagu O, Raabe VN, Severance R, Rivas E, Romanyak N, Rouphael NG, Schuerman L, Sher LD, Walsh SR, White J, von Barbier D, de Bruyn G, Canter R, Grillet MH, Keshtkar-Jahromi M, Koutsoukos M, Lopez D, Masotti R, Mendoza S, Moreau C, Ceregido MA, Ramirez S, Said A, Tavares-Da-Silva F, Shi J, Tong T, Treanor J, Diazgranados CA, Savarino S. "Safety and immunogenicity of an AS03-adjuvanted SARS-CoV-2 recombinant protein vaccine (CoV2 preS dTM) in healthy adults: interim findings from a phase 2, randomised, dose-finding, multicentre study." The Lancet. Infectious diseases.. 2022 Jan 25; Epub 2022 Jan 25.
2022
Croix MC, Munsiff SS. "cavitary lung disease progression over a three year period - A case report." IDCases.. 2022 27:e01379. Epub 2022 Jan 05.
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