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Angela Branche, M.D.

Contact Information

Phone Numbers

Appointment: (585) 273-0526

Office: (585) 273-4104

Fax: (585) 442-9328

URMFGA member of the University of Rochester Medical Faculty Group

groupAn Accountable Health Partner

assignmentAccepting New Patients

Faculty Appointments

Patient Care Setting

Infectious Diseases

Biography

Professional Background

Dr. Branche is an assistant professor at the University of Rochester, School of Medicine. She received her Bachelor of Arts degree in Biology at the University of Pennsylvania and Doctorate in Medicine at American University of the Caribbean. She completed residency in Internal Medicine at NYU Lutheran in Brooklyn, NY and infectious disease fellowship at the University of Rochester. She currently has a clinical inpatient practice comprised of both general infectious diseases and HIV medicine patients. Dr. Branche is also a New York State designated HIV/AIDS provider and has a practice comprised of adult patients ages 18 and older at the URMC HIV Clinic.

Research

During her years at the University of Rochester her focus in research involved the use of viral molecular and immunological diagnostic assays to explore the pathogenesis and host response to acute viral respiratory illnesses in adults. She is currently the clinical director of the NIH Center for Excellent in Influenza Research and Surveillance (CEIRS) New York Influenza Center of Excellence (NYICE) and Co-Principle Investigator for the UR Vaccine Treatment and Evaluation Unit (UR VTEU). Her current research activities explore clinical disease, pathogenesis, development of therapeutics and vaccine biology related to infection with viral and bacterial respiratory pathogens. Studies include assessment of asymptomatic carriage of Streptococcus pneumoniae and the impact of pneumococcal vaccination, surveillance of epidemic influenza infections and immunologic mechanisms of protection following natural infection versus vaccination, the development of pandemic influenza vaccines, population-based studies of RSV infection and the development of vaccine and anti-viral agents for RSV. Current efforts also include the study of the pathogenesis and immune response to pandemic SARS Coronavirus 2 infections and clinical interventional trials for the development of COVID19 therapeutic agents and vaccines. She is a member of the Infectious Disease Society of America and the NIH Human Cohorts Steering Committee and NIH IDCRC Emerging Infectious Expert Working Group. Dr. Branche has published several peer-reviewed articles, reviews and book chapters related to respiratory viral pathogens in adults.

Credentials

Specialties

  • Infectious Disease - American Board of Internal Medicine
  • Internal Medicine - American Board of Internal Medicine

Education

2007
MD | American University of the Caribbean

Post-doctoral Training & Residency

07/01/2012 - 06/30/2014
Fellowship in Infectious Disease at University of Rochester Medical Center

07/01/2009 - 06/30/2011
Residency in Internal Medicine at Lutheran Medical Center

07/01/2008 - 06/30/2009
Internship in Internal Medicine at Lutheran Medical Center

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Clinical Trials

A descriptive study of the pathogenesis of acute influenza and evaluation of the pathogenesis and immune response to SARS-CoV-2 during2020 COVID-19 pandemic in adults, children, and the elderly

Lead Researcher: Angela Branche

This study will obtain timed samples of blood and nasal secretions from adults, children, and the elderly with influenza-like illness. It will look to characterize the pathogenesis (mechanisms of infection/illness) and the responses that occur within the immune system - for both COVID-19 and influenza.

View Study Details

Publications

Journal Articles

10/8/2020
Beigel JH, Tomashek KM, Dodd LE, Mehta AK, Zingman BS, Kalil AC, Hohmann E, Chu HY, Luetkemeyer A, Kline S, Lopez de Castilla D, Finberg RW, Dierberg K, Tapson V, Hsieh L, Patterson TF, Paredes R, Sweeney DA, Short WR, Touloumi G, Lye DC, Ohmagari N, Oh MD, Ruiz-Palacios GM, Benfield T, Fätkenheuer G, Kortepeter MG, Atmar RL, Creech CB, Lundgren J, Babiker AG, Pett S, Neaton JD, Burgess TH, Bonnett T, Green M, Makowski M, Osinusi A, Nayak S, Lane HC. "Remdesivir for the Treatment of Covid-19 - Final Report." The New England journal of medicine.. 2020 Oct 8; Epub 2020 Oct 08.

9/25/2020
Nguyen-Contant P, Embong AK, Kanagaiah P, Chaves FA, Yang H, Branche AR, Topham DJ, Sangster MY. "S Protein-Reactive IgG and Memory B Cell Production after Human SARS-CoV-2 Infection Includes Broad Reactivity to the S2 Subunit." mBio.. 2020 Sep 25; 11(5)Epub 2020 Sep 25.

2020
Richards KA, Moritzky S, Shannon I, Fitzgerald T, Yang H, Branche A, Topham DJ, Treanor JJ, Nayak J, Sant AJ. "Recombinant HA-based vaccine outperforms split and subunit vaccines in elicitation of influenza-specific CD4 T cells and CD4 T cell-dependent antibody responses in humans." NPJ vaccines.. 2020 5:77. Epub 2020 Aug 26.

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