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Isaac Schmale, M.D.

Contact Information

Phone Numbers

Appointment: (585) 758-5700

URMFGA member of the University of Rochester Medical Faculty Group

groupAn Accountable Health Partner

assignmentAccepting New Patients

Faculty Appointments

Patient Care Setting



Dr. Isaac Schmale earned his medical degree from the Keck School of Medicine of USC in Los Angeles, CA. He completed his residency in Otolaryngology – Head and Neck Surgery at the University of Rochester School of Medicine and Dentistry. Dr. Schmale continued his education and completed a fellowship in Advanced Rhinology, Neurorhinology and Endoscopic Skull Base Surgery at the Texas Sinus Institute in the Department of Otorhinolaryngology-Head and Neck Surgery at McGovern Medical School, The University of Texas Health Science Center at Houston.

Area of focus include:
- Medical and surgical treatment of chronic rhinosinusitis
- Revision sinus surgery
- In-Office treatment for nasal breathing and sinus conditions
- Nasal polyps
- Endoscopic sinus surgery
- Endoscopic skull base surgery
- Endoscopic pituitary surgery
- Treatment of Benign and malignant nasal tumors
- Treatment of Skull-base tumors
- Deviated nasal septum
- Cerebrospinal fluid leak repair
- Anosmia (smell loss)
- Endoscopic lacrimal surgery
- Endoscopic orbital surgery
- Aspirin-exacerbated respiratory disease (AERD)



  • Otolaryngology - American Board of Otolaryngology


MD | University of Southern California School of Pharmacy

Post-doctoral Training & Residency

07/16/2019 - 07/15/2020
Fellowship at Memorial Hermann Hospital-Texas Medical Center

07/01/2014 - 06/30/2019
Residency in Otolaryngology at University of Rochester Medical Center


Journal Articles

Nimmagadda SV, Schmale IL, Man LX. "Crenotherapy as a Complementary and Integrative Treatment for Chronic Rhinosinusitis: A Systematic Review and Discussion of Current Evidence Limitations." American journal of rhinology & allergy.. 2022 Feb 23; :19458924221081235. Epub 2022 Feb 23.

Saini AT, Jiang ZY, Starr NC, Talmadge J, Schmale I, Radabaugh P, Yao WC, Luong AU, Citardi MJ. "Are nonsteroidal anti-inflammatory drugs effective enough for postoperative pain control after functional endoscopic sinus surgery and septoplasty? A randomized, controlled study." International forum of allergy & rhinology.. 2021 Dec 22; Epub 2021 Dec 22.

Tyler MA, Lam K, Marino MJ, Yao WC, Schmale I, Citardi MJ, Luong AU. "Revisiting the controversy: The role of fungi in chronic rhinosinusitis." International forum of allergy & rhinology.. 2021 Nov; 11(11):1577-1587. Epub 2021 Jun 02.