Her clinical interests are focused on various types of food allergy, including immediate-type allergies, eosinophilic gastrointestinal disease, food protein-induced enterocolitis, allergic proctocolitis, atopic dermatitis, and anaphylaxis, although she also sees patients with other allergic disorders such as asthma, allergic rhinitis, urticaria and angioedema. She is the Director for the Food Allergy Center, which is a multidisciplinary program that provides comprehensive care to families including specialists in gastroenterology, dermatology, pathology and dieticians. Her research program is focused on identifying protective mechanisms against food allergy, including breast milk factors.
Dr. Järvinen-Seppo is an Allergist and Immunologist at the Strong Memorial Hospital. She received her M.D. and Ph.D. degrees at the University of Helsinki, Finland. She initially joined the Jaffe Institute for Food Allergy at the Icahn School of Medicine at Mount Sinai, New York City for a post-doctoral research fellowship and subsequently as an Instructor. She completed a residency in Pediatrics and a fellowship in Allergy and Immunology at the Mount Sinai Hospital. She stayed as an Assistant Professor at the Jaffe Institute for Food Allergy at Mount Sinai School of Medicine followed by a faculty position at the Albany Medical College before joining University of Rochester Medical Center in 2014.
My research interests focus on food allergies disorders, caused by milk, egg and peanut. In particular, my research program is focusing on mechanisms of food allergy and development of neonatal oral tolerance to foods. My laboratory is trying to understand the role of breastfeeding and immunomodulatory factors in breast milk on the development of mucosal immune system and immune responses to foods in the offspring.
Other research interests include etiology and treatment of food-induced anaphylaxis, animal models of food allergy, oral immunotherapy.
NIH NIAID Physician Scientist Award
AAAAI Jaffe Food Allergy Research Award
Sponsor: American Academy of Allergy, Asthma, and Immunology
Third-Year Fellow-in-Training Research Award
Sponsor: American Academy of Allergy, Asthma, and Immunology (AAAAI)
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Järvinen KM, Suárez-Fariñas M, Savilahti E, Sampson HA, Berin MC. "Immune factors in breast milk related to infant milk allergy are independent of maternal atopy." The Journal of allergy and clinical immunology.. 2015 May 0; 135(5):1390-3.e1-6. Epub 2014 Dec 19.
Adams J, Voutilainen H, Ullner PM, Järvinen KM. "The safety of maternal elimination diets in breastfeeding mothers with food-allergic infants." Breastfeeding medicine : the official journal of the Academy of Breastfeeding Medicine.. 2014 Dec 0; 9(10):555-6.
Tordesillas L, Goswami R, Benedé S, Grishina G, Dunkin D, Järvinen KM, Maleki SJ, Sampson HA, Berin MC. "Skin exposure promotes a Th2-dependent sensitization to peanut allergens." The Journal of clinical investigation.. 2014 Nov 0; 124(11):4965-75. Epub 2014 Oct 08.
Books & Chapters
Chapter Title: Breast- always best?
Book Title: Allergy, immunity and tolerance in early childhood: The first two thousand days of the Atopic March
Author List: Järvinen KM, Bergmann R.
Edited By: Wahn U, Sampson HA (eds).
Published By: Elsevier2014
Chapter Title: Food-Induced Anaphylaxis
Book Title: Anaphylaxis and Hypersensitivity Reactions from Molecular Markers to Rapid Desensitizations.
Author List: Järvinen KM, Nowak-Wegrzyn A.
Edited By: Castells MC (ed).
Published By: Springer2011 in New York
Chapter Title: IgA in human milk and development of cow's milk allergy in the breast-fed infant
Book Title: Integrating population outcomes, biological mechanisms and research methods in the study of human milk and lactation
Author List: Järvinen K-M, Laine S, Järvenpää A-L, Suomalainen H.
Edited By: Davis MK, Isaacs CE, Hanson LA, Wright AL (eds).
Published By: Kluwer Academic/Plenum Publishers2002 in New York
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