David C. Linehan, M.D.

Dr. Linehan graduated from the University of Massachusetts Medical School then completed his internship and residency at Deaconess-Harvard Surgical Service. He was chief resident in Surgery at Beth Israel Deaconess Medical Center. He completed a research fellowship at Brigham and Women's Hospital and was then the Kristin Ann Carr Fellow in Surgical Oncology at Memorial Sloan-Kettering Cancer Center.
A cancer surgeon, Dr. Linehan specializes in treating cancers of the liver, pancreas, and gastric and biliary tract. At Washington University, he was recognized for bringing novel and innovative therapies to patients with hard-to-treat cancers. He also brought a compassionate, patient-centered approach to a high-volume surgical oncology practice. Dr. Linehan also treats benign surgical conditions of the liver, pancreas, gallbladder and bile ducts.
Dr. Linehan is an internationally renowned researcher, with more than 85 publications. His primary area of research is finding new ways to attack the biology of pancreatic tumors, such as through drug and genetic therapies.

Credentials

Specialties

Surgery - American Board of Surgery

Education

1986
BA | Dartmouth College
Religion

1990
MD | University of Massachusetts Medical School
Medicine

Post-doctoral Training & Residency

07/01/1997 - 06/30/1999
Fellowship in Surgical Oncology at Memorial Sloan-Kettering Cancer Center

09/01/1996 - 06/30/1997
Fellowship in Surgery at Beth Israel Deaconess Medical Center

08/01/1993 - 06/01/1995
Fellowship in at Brigham and Women's Hospital

09/01/1991 - 06/30/1996
Residency in Surgery at Beth Israel Deaconess Medical Center

09/01/1990 - 06/30/1991
Internship in Surgery at Beth Israel Deaconess Medical Center

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Awards

2012
Inaugural Gerry O'Sullivan Memorial Lecturer Award
Sponsor: University College
Location: Cork, Ireland

2006
CTRF Superhero Cancer Researcher Award
Location: Chicago, IL

2004
Evarts A. Graham Teaching Award
Sponsor: Washington University School of Medicine
Location: St. Louis, MO

1999
Young Investigator Award
Sponsor: American Society of Clinical Oncology

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Publications

Journal Articles

11/21/2019
Rashid NU, Peng XL, Jin C, Moffitt RA, Volmar KE, Belt BA, Panni RZ, Nywening TM, Herrera SG, Moore KJ, Hennessey SG, Morrison AB, Kawalerski R, Nayyar A, Chang AE, Schmidt B, Kim HJ, Linehan DC, Yeh JJ. "Purity Independent Subtyping of Tumors (PurIST), A Clinically Robust, Single-sample Classifier for Tumor Subtyping in Pancreatic Cancer." Clinical cancer research : an official journal of the American Association for Cancer Research.. 2019 Nov 21; Epub 2019 Nov 21.

11/12/2019
Ye J, Mills BN, Zhao T, Han BJ, Murphy JD, Patel AP, Johnston CJ, Lord EM, Belt BA, Linehan DC, Gerber SA. "Assessing the Magnitude of Immunogenic Cell Death Following Chemotherapy and Irradiation Reveals a New Strategy to Treat Pancreatic Cancer." Cancer immunology research.. 2019 Nov 12; Epub 2019 Nov 12.

7/12/2019
Noel M, O'Reilly EM, Wolpin BM, Ryan DP, Bullock AJ, Britten CD, Linehan DC, Belt BA, Gamelin EC, Ganguly B, Yin D, Joh T, Jacobs IA, Taylor CT, Lowery MA. "Phase 1b study of a small molecule antagonist of human chemokine (C-C motif) receptor 2 (PF-04136309) in combination with nab-paclitaxel/gemcitabine in first-line treatment of metastatic pancreatic ductal adenocarcinoma." Investigational new drugs.. 2019 Jul 12; Epub 2019 Jul 12.

Books & Chapters

2007
Book Title: Surgery of the Liver, Biliary Tract and Pancreas
Author List: Linehan DC and Jarnagin WR
Edited By: Blumgart LH, Editor-in-Chief
Published By: Elsevier 2007 in Philadelphia

2002
Chapter Title: Thermal Ablation of Liver Tumors by Radiofrequency, Microwave, and Laser Therapy
Book Title: Malignant Liver Tumors: Current and Emerging Therapies
Author List: Strasberg SM and Linehan DC
Published By: Bartlett and Barnes 2002 in Chicago

2001
Chapter Title: Active Immunotherapy
Book Title: Surgical Research
Author List: Linehan DC; Amos K; Eberlein TJ
Edited By: Souba WW and Wilmore, DW
Published By: Academic Press 2001 in San Diego, CA

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