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David C. Linehan, M.D.

Cancer, Surgery

Publications

Showing all 108 journal articles & 4 books available

Journal Articles

5/17/2017
Tomiyama K, Hernandez-Alejandro R, Linehan DC. "Staging for Intrahepatic Cholangiocarcinoma: Are We Getting Close to Understanding the True Tumor Biology?" JAMA surgery.. 2017 May 17; 152(5):e170108. Epub 2017 May 17.

5/2017
Ohman KA, Liu J, Linehan DC, Tan MC, Tan BR, Fields RC, Strasberg SM, Hawkins WG. "Interferon-based chemoradiation followed by gemcitabine for resected pancreatic adenocarcinoma: long-term follow-up." HPB : the official journal of the International Hepato Pancreato Biliary Association.. 2017 May 0; 19(5):449-457. Epub 2017 Feb 03.

3/15/2017
Hernandez-Alejandro R, Levstik MA, Linehan DC. "Hepatectomy for Early Hepatocellular Carcinoma: Not If, but When and How?" JAMA surgery.. 2017 Mar 15; 152(3):e165042. Epub 2017 Mar 15.

12/27/2016
Connolly KA, Belt BA, Figueroa NM, Murthy A, Patel A, Kim M, Lord EM, Linehan DC, Gerber SA. "Increasing the efficacy of radiotherapy by modulating the CCR2/CCR5 chemokine axes." Oncotarget. 2016 Dec 27; 7(52):86522-86535.

8/2016
Jin LX, Sanford DE, Squires MH, Moses LE, Yan Y, Poultsides GA, Votanopoulos KI, Weber SM, Bloomston M, Pawlik TM, Hawkins WG, Linehan DC, Schmidt C, Worhunsky DJ, Acher AW, Cardona K, Cho CS, Kooby DA, Levine EA, Winslow E, Saunders N, Spolverato G, Colditz GA, Maithel SK, Fields RC. "Interaction of Postoperative Morbidity and Receipt of Adjuvant Therapy on Long-Term Survival After Resection for Gastric Adenocarcinoma: Results From the U.S. Gastric Cancer Collaborative." Annals of surgical oncology.. 2016 Aug 0; 23(8):2398-408. Epub 2016 Mar 22.

5/1/2016
Schoeniger LO, Linehan DC. "Wound Infections After Pancreaticoduodenectomy." JAMA surgery.. 2016 May 1; 151(5):440.

5/2016
Nywening TM, Wang-Gillam A, Sanford DE, Belt BA, Panni RZ, Cusworth BM, Toriola AT, Nieman RK, Worley LA, Yano M, Fowler KJ, Lockhart AC, Suresh R, Tan BR, Lim KH, Fields RC, Strasberg SM, Hawkins WG, DeNardo DG, Goedegebuure SP, Linehan DC. "Targeting tumour-associated macrophages with CCR2 inhibition in combination with FOLFIRINOX in patients with borderline resectable and locally advanced pancreatic cancer: a single-centre, open-label, dose-finding, non-randomised, phase 1b trial." The Lancet. Oncology.. 2016 May 0; 17(5):651-62. Epub 2016 Apr 04.

3/2016
Owen JW, Fowler KJ, Doyle MB, Saad NE, Linehan DC, Chapman WC. "Colorectal liver metastases: disappearing lesions in the era of Eovist hepatobiliary magnetic resonance imaging." HPB : the official journal of the International Hepato Pancreato Biliary Association.. 2016 Mar 0; 18(3):296-303. Epub 2016 Mar 14.

2/2016
Badiyan SN, Olsen JR, Lee AY, Yano M, Menias CO, Khwaja S, Wang-Gillam A, Strasberg SM, Hawkins WG, Linehan DC, Myerson RJ, Parikh PJ. "Induction Chemotherapy Followed by Concurrent Full-dose Gemcitabine and Intensity-modulated Radiation Therapy for Borderline Resectable and Locally Advanced Pancreatic Adenocarcinoma." American journal of clinical oncology.. 2016 Feb 0; 39(1):1-7.

12/2015
Jin LX, Moses LE, Squires MH, Poultsides GA, Votanopoulos K, Weber SM, Bloomston M, Pawlik TM, Hawkins WG, Linehan DC, Strasberg SM, Schmidt C, Worhunsky DJ, Acher AW, Cardona K, Cho CS, Kooby DA, Levine E, Winslow ER, Saunders ND, Spolverato G, Maithel SK, Fields RC. "Factors Associated With Recurrence and Survival in Lymph Node-negative Gastric Adenocarcinoma: A 7-Institution Study of the US Gastric Cancer Collaborative." Annals of surgery.. 2015 Dec 0; 262(6):999-1005.

7/7/2015
Sausen M, Phallen J, Adleff V, Jones S, Leary RJ, Barrett MT, Anagnostou V, Parpart-Li S, Murphy D, Kay Li Q, Hruban CA, Scharpf R, White JR, O'Dwyer PJ, Allen PJ, Eshleman JR, Thompson CB, Klimstra DS, Linehan DC, Maitra A, Hruban RH, Diaz LA, Von Hoff DD, Johansen JS, Drebin JA, Velculescu VE. "Clinical implications of genomic alterations in the tumour and circulation of pancreatic cancer patients." Nature communications. 2015 Jul 7; 6:7686. Epub 2015 Jul 07.

7/2015
Cho M, Wang-Gillam A, Myerson R, Gao F, Strasberg S, Picus J, Sorscher S, Fournier C, Nagaraj G, Parikh P, Suresh R, Linehan D, Tan BR. "A phase II study of adjuvant gemcitabine plus docetaxel followed by concurrent chemoradation in resected pancreaticobiliary carcinoma." HPB : the official journal of the International Hepato Pancreato Biliary Association.. 2015 Jul 0; 17(7):587-93. Epub 2015 Mar 20.

6/2015
Linehan D, Galka E. "Lingering Questions on Choledochal Cysts." JAMA surgery.. 2015 Jun 0; 150(6):584.

5/2015
Chang ST, Nguyen DC, Raptis C, Menias CO, Zhou G, Wang-Gillam A, Linehan DC, Hawkins WG, Strasberg SM, Fields RC. "Natural history of preoperative subcentimeter pulmonary nodules in patients with resectable pancreatic adenocarcinoma: a retrospective cohort study." Annals of surgery.. 2015 May 0; 261(5):970-5.

1/2015
Fowler KJ, Saad NE, Linehan D. "Imaging approach to hepatocellular carcinoma, cholangiocarcinoma, and metastatic colorectal cancer." Surgical oncology clinics of North America.. 2015 Jan 0; 24(1):19-40. Epub 2014 Oct 11.

2015
Pepin E, Olsen L, Badiyan S, Murad F, Mullady D, Wang-Gillam A, Linehan D, Parikh P, Olsen J. "Comparison of implanted fiducial markers and self-expandable metallic stents for pancreatic image guided radiation therapy localization." Practical radiation oncology.. 2015 5(3):e193-9. Epub 2014 Oct 03.

2015
Zhong H, Sanchez C, Spitrzer D, Plambeck-Suess S, Gibbs J, Hawkins WG, Denardo D, Gao F, Pufahl RA, Lockhart AC, Xu M, Linehan D, Weber J, Wang-Gillam A. "Correction: Synergistic Effects of Concurrent Blockade of PI3K and MEK Pathways in Pancreatic Cancer Preclinical Models." PloS one. 2015 10(4):e0127365. Epub 2015 Apr 27.

12/2014
Sanford DE, Sanford AM, Fields RC, Hawkins WG, Strasberg SM, Linehan DC. "Severe nutritional risk predicts decreased long-term survival in geriatric patients undergoing pancreaticoduodenectomy for benign disease." Journal of the American College of Surgeons.. 2014 Dec 0; 219(6):1149-56. Epub 2014 Jun 30.

11/2014
Sanford DE, Olsen MA, Bommarito KM, Shah M, Fields RC, Hawkins WG, Jaques DP, Linehan DC. "Association of discharge home with home health care and 30-day readmission after pancreatectomy." Journal of the American College of Surgeons.. 2014 Nov 0; 219(5):875-86.e1. Epub 2014 Jul 18.

10/2014
Nalbantoglu I, Tan BR, Linehan DC, Gao F, Brunt EM. "Histological features and severity of oxaliplatin-induced liver injury and clinical associations." Journal of digestive diseases.. 2014 Oct 0; 15(10):553-60.

9/15/2014
Zhu Y, Knolhoff BL, Meyer MA, Nywening TM, West BL, Luo J, Wang-Gillam A, Goedegebuure SP, Linehan DC, DeNardo DG. "CSF1/CSF1R blockade reprograms tumor-infiltrating macrophages and improves response to T-cell checkpoint immunotherapy in pancreatic cancer models." Cancer research.. 2014 Sep 15; 74(18):5057-69. Epub 2014 Jul 31.

9/2014
Sanford DE, Woolsey CA, Hall BL, Linehan DC, Hawkins WG, Fields RC, Strasberg SM. "Variations in definition and method of retrieval of complications influence outcomes statistics after pancreatoduodenectomy: comparison of NSQIP with non-NSQIP methods." Journal of the American College of Surgeons.. 2014 Sep 0; 219(3):407-15. Epub 2014 Apr 18.

8/2014
Benson AB, D'Angelica MI, Abrams TA, Are C, Bloomston PM, Chang DT, Clary BM, Covey AM, Ensminger WD, Iyer R, Kelley RK, Linehan D, Malafa MP, Meranze SG, Park JO, Pawlik T, Posey JA, Scaife C, Schefter T, Sigurdson ER, Tian GG, Vauthey JN, Venook AP, Yen Y, Zhu AX, Hoffmann KG, McMillian NR, Sundar H. "Hepatobiliary cancers, version 2.2014." Journal of the National Comprehensive Cancer Network : JNCCN.. 2014 Aug 0; 12(8):1152-82.

5/2014
Jin LX, Fields RC, Hawkins WG, Linehan DC, Strasberg SM. "A new operative approach for type I choledochal cysts." Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract.. 2014 May 0; 18(5):1049-53. Epub 2013 Nov 13.

5/2014
Panni RZ, Sanford DE, Belt BA, Mitchem JB, Worley LA, Goetz BD, Mukherjee P, Wang-Gillam A, Link DC, Denardo DG, Goedegebuure SP, Linehan DC. "Tumor-induced STAT3 activation in monocytic myeloid-derived suppressor cells enhances stemness and mesenchymal properties in human pancreatic cancer." Cancer immunology, immunotherapy : CII.. 2014 May 0; 63(5):513-28. Epub 2014 Mar 21.

2/2014
Strasberg SM, Gao F, Sanford D, Linehan DC, Hawkins WG, Fields R, Carpenter DH, Brunt EM, Phillips C. "Jaundice: an important, poorly recognized risk factor for diminished survival in patients with adenocarcinoma of the head of the pancreas." HPB : the official journal of the International Hepato Pancreato Biliary Association.. 2014 Feb 0; 16(2):150-6. Epub 2013 Apr 22.

2/2014
Hashim YM, Trinkaus KM, Linehan DC, Strasberg SS, Fields RC, Cao D, Hawkins WG. "Regional lymphadenectomy is indicated in the surgical treatment of pancreatic neuroendocrine tumors (PNETs)." Annals of surgery.. 2014 Feb 0; 259(2):197-203.

11/2013
Idrees K, Edler JR, Linehan DC, Strasberg SM, Jacques D, Hamilton NA, Fields RC, Lambert D, Kymes S, Hawkins WG. "Cost benefit analysis of mesh reinforcement of stapled left pancreatectomy." HPB : the official journal of the International Hepato Pancreato Biliary Association.. 2013 Nov 0; 15(11):893-8. Epub 2013 Feb 20.

10/21/2013
Capietto AH, Kim S, Sanford DE, Linehan DC, Hikida M, Kumosaki T, Novack DV, Faccio R. "Down-regulation of PLC?2-?-catenin pathway promotes activation and expansion of myeloid-derived suppressor cells in cancer." The Journal of experimental medicine.. 2013 Oct 21; 210(11):2257-71. Epub 2013 Oct 14.

10/2013
Panni RZ, Linehan DC, DeNardo DG. "Targeting tumor-infiltrating macrophages to combat cancer." Immunotherapy.. 2013 Oct 0; 5(10):1075-87.

7/1/2013
Sanford DE, Belt BA, Panni RZ, Mayer A, Deshpande AD, Carpenter D, Mitchem JB, Plambeck-Suess SM, Worley LA, Goetz BD, Wang-Gillam A, Eberlein TJ, Denardo DG, Goedegebuure SP, Linehan DC. "Inflammatory monocyte mobilization decreases patient survival in pancreatic cancer: a role for targeting the CCL2/CCR2 axis." Clinical cancer research : an official journal of the American Association for Cancer Research.. 2013 Jul 1; 19(13):3404-15. Epub 2013 May 07.

4/2013
Fowler KJ, Linehan DC, Menias CO. "Colorectal liver metastases: state of the art imaging." Annals of surgical oncology.. 2013 Apr 0; 20(4):1185-93. Epub 2012 Nov 01.

2/1/2013
Mitchem JB, Brennan DJ, Knolhoff BL, Belt BA, Zhu Y, Sanford DE, Belaygorod L, Carpenter D, Collins L, Piwnica-Worms D, Hewitt S, Udupi GM, Gallagher WM, Wegner C, West BL, Wang-Gillam A, Goedegebuure P, Linehan DC, DeNardo DG. "Targeting tumor-infiltrating macrophages decreases tumor-initiating cells, relieves immunosuppression, and improves chemotherapeutic responses." Cancer research.. 2013 Feb 1; 73(3):1128-41. Epub 2012 Dec 05.

2013
Zhong H, Sanchez C, Spitzer D, Spitrzer D, Plambeck-Suess S, Gibbs J, Hawkins WG, Denardo D, Gao F, Pufahl RA, Lockhart AC, Xu M, Linehan D, Weber J, Wang-Gillam A. "Synergistic effects of concurrent blockade of PI3K and MEK pathways in pancreatic cancer preclinical models." PloS one. 2013 8(10):e77243. Epub 2013 Oct 09.

9/2012
Porembka MR, Mitchem JB, Belt BA, Hsieh CS, Lee HM, Herndon J, Gillanders WE, Linehan DC, Goedegebuure P. "Pancreatic adenocarcinoma induces bone marrow mobilization of myeloid-derived suppressor cells which promote primary tumor growth." Cancer immunology, immunotherapy : CII.. 2012 Sep 0; 61(9):1373-85. Epub 2012 Jan 04.

1/2012
Mitchem JB, Hamilton N, Gao F, Hawkins WG, Linehan DC, Strasberg SM. "Long-term results of resection of adenocarcinoma of the body and tail of the pancreas using radical antegrade modular pancreatosplenectomy procedure." Journal of the American College of Surgeons.. 2012 Jan 0; 214(1):46-52.

2012
Linehan, DC. "The right way to do a Whipple procedure: comment on 'Stenting and the rate of pancreatic fistula following pancreaticoduodenectomy'". Archives of Surgery. 2012; 147(1): 41.

9/2011
Porembka MR, Hawkins WG, Linehan DC, Gao F, Ma C, Brunt EM, Strasberg SM. "Radiologic and intraoperative detection of need for mesenteric vein resection in patients with adenocarcinoma of the head of the pancreas." HPB : the official journal of the International Hepato Pancreato Biliary Association.. 2011 Sep 0; 13(9):633-42.

8/2011
Khan AS, Hawkins WG, Linehan DC, Strasberg SM. "A technique of gastrojejunostomy to reduce delayed gastric emptying after pancreatoduodenectomy." Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract.. 2011 Aug 0; 15(8):1468-71. Epub 2011 Feb 24.

7/2011
Goedegebuure P, Mitchem JB, Porembka MR, Tan MC, Belt BA, Wang-Gillam A, Gillanders WE, Hawkins WG, Linehan DC. "Myeloid-derived suppressor cells: general characteristics and relevance to clinical management of pancreatic cancer." Current cancer drug targets.. 2011 Jul 0; 11(6):734-51.

2/11/2011
Subramaniam D, Ramalingam S, Linehan DC, Dieckgraefe BK, Postier RG, Houchen CW, Jensen RA, Anant S. "RNA binding protein CUGBP2/CELF2 mediates curcumin-induced mitotic catastrophe of pancreatic cancer cells." PloS one. 2011 Feb 11; 6(2):e16958. Epub 2011 Feb 11.

2/2011
Pai RK, Beck AH, Mitchem J, Linehan DC, Chang DT, Norton JA, Pai RK. "Pattern of lymph node involvement and prognosis in pancreatic adenocarcinoma: direct lymph node invasion has similar survival to node-negative disease." The American journal of surgical pathology.. 2011 Feb 0; 35(2):228-34.

2011
Linehan, DC; Jaques D. "Choosing 'The Best'". Archives of Surgery. 2011; 146(5): 604-5.

10/1/2010
Gnerlich JL, Mitchem JB, Weir JS, Sankpal NV, Kashiwagi H, Belt BA, Porembka MR, Herndon JM, Eberlein TJ, Goedegebuure P, Linehan DC. "Induction of Th17 cells in the tumor microenvironment improves survival in a murine model of pancreatic cancer." The Journal of immunology : official journal of the American Association of Immunologists.. 2010 Oct 1; 185(7):4063-71. Epub 2010 Aug 30.

8/2010
Wu YV, Linehan DC. "Bile duct injuries in the era of laparoscopic cholecystectomies." The Surgical clinics of North America.. 2010 Aug 0; 90(4):787-802.

3/2010
Fox AC, Robertson CM, Belt B, Clark AT, Chang KC, Leathersich AM, Dominguez JA, Perrone EE, Dunne WM, Hotchkiss RS, Buchman TG, Linehan DC, Coopersmith CM. "Cancer causes increased mortality and is associated with altered apoptosis in murine sepsis." Critical care medicine.. 2010 Mar 0; 38(3):886-93.

1/20/2010
Dandona M, Gao F, Linehan DC, Wang-Gillam A. "Re: ABO blood group and the risk of pancreatic cancer." Journal of the National Cancer Institute.. 2010 Jan 20; 102(2):135-7; author reply 137. Epub 2009 Dec 17.

2010
Logan S and Linehan DC. "Benign and Malignant Bilary Tract Disease". Journal of the ACS. 2010; .

11/1/2009
Johnston FM, Tan MC, Tan BR, Porembka MR, Brunt EM, Linehan DC, Simon PO, Plambeck-Suess S, Eberlein TJ, Hellstrom KE, Hellstrom I, Hawkins WG, Goedegebuure P. "Circulating mesothelin protein and cellular antimesothelin immunity in patients with pancreatic cancer." Clinical cancer research : an official journal of the American Association for Cancer Research.. 2009 Nov 1; 15(21):6511-8. Epub 2009 Oct 20.

8/2009
Strasberg SM, Linehan DC, Hawkins WG. "The accordion severity grading system of surgical complications." Annals of surgery.. 2009 Aug 0; 250(2):177-86.

7/2009
Callery MP, Chang KJ, Fishman EK, Talamonti MS, William Traverso L, Linehan DC. "Pretreatment assessment of resectable and borderline resectable pancreatic cancer: expert consensus statement." Annals of surgical oncology.. 2009 Jul 0; 16(7):1727-33. Epub 2009 Apr 24.

7/2009
Gnerlich JL, Ritter JH, Linehan DC, Hawkins WG, Strasberg SM. "Saline-linked surface radiofrequency ablation: a safe and effective method of surface ablation of hepatic metastatic colorectal cancer." Annals of surgery.. 2009 Jul 0; 250(1):96-102.

3/15/2009
Rupp CC, Linehan DC. "Extended lymphadenectomy in the surgery of pancreatic adenocarcinoma and its relation to quality improvement issues." Journal of surgical oncology.. 2009 Mar 15; 99(4):207-14.

2/1/2009
Tan MC, Goedegebuure PS, Belt BA, Flaherty B, Sankpal N, Gillanders WE, Eberlein TJ, Hsieh CS, Linehan DC. "Disruption of CCR5-dependent homing of regulatory T cells inhibits tumor growth in a murine model of pancreatic cancer." The Journal of immunology : official journal of the American Association of Immunologists.. 2009 Feb 1; 182(3):1746-55.

2/2009
Johnston FM, Cavataio A, Strasberg SM, Hamilton NA, Simon PO, Trinkaus K, Doyle MB, Mathews BD, Porembka MR, Linehan DC, Hawkins WG. "The effect of mesh reinforcement of a stapled transection line on the rate of pancreatic occlusion failure after distal pancreatectomy: review of a single institution's experience." HPB : the official journal of the International Hepato Pancreato Biliary Association.. 2009 Feb 0; 11(1):25-31.

1/2009
Moo-Young TA, Larson JW, Belt BA, Tan MC, Hawkins WG, Eberlein TJ, Goedegebuure PS, Linehan DC. "Tumor-derived TGF-beta mediates conversion of CD4+Foxp3+ regulatory T cells in a murine model of pancreas cancer." Journal of immunotherapy.. 2009 Jan 0; 32(1):12-21.

2009
Cescon, et al. "Invited Editorial Commentary on " A simple algorithm based on preoperative variables can indicated the extent of hepatecomty for hepatocellular carcinoma in cirrhoitc patients". Arch Surg. 2009; 144(1).

2009
Winslow ER; Fialkowski EA; Linehan DC; Hawkins WG; Picus DD; Strasberg SM. "'Sideways': results of repair of biliary injuries using a policy of side-to-side hepatico-jejunostomy". Annals of Surgery. 2009; 249(3): 426-34.

12/2008
Sexton JA, Pierce RA, Halpin VJ, Eagon JC, Hawkins WG, Linehan DC, Brunt LM, Frisella MM, Matthews BD. "Laparoscopic gastric resection for gastrointestinal stromal tumors." Surgical endoscopy.. 2008 Dec 0; 22(12):2583-7. Epub 2008 Mar 06.

8/2008
Linehan DC, Tan MC, Strasberg SM, Drebin JA, Hawkins WG, Picus J, Myerson RJ, Malyapa RS, Hull M, Trinkaus K, Tan BR. "Adjuvant interferon-based chemoradiation followed by gemcitabine for resected pancreatic adenocarcinoma: a single-institution phase II study." Annals of surgery.. 2008 Aug 0; 248(2):145-51.

5/2008
Tan MC, Castaldo ET, Gao F, Chari RS, Linehan DC, Wright JK, Hawkins WG, Siegel BA, Delbeke D, Pinson CW, Strasberg SM. "A prognostic system applicable to patients with resectable liver metastasis from colorectal carcinoma staged by positron emission tomography with [18F]fluoro-2-deoxy-D-glucose: role of primary tumor variables." Journal of the American College of Surgeons.. 2008 May 0; 206(5):857-68; discussion 868-9. Epub 2008 Mar 17.

2/2008
Strasberg SM, Linehan DC, Hawkins WG. "Isolation of right main and right sectional portal pedicles for liver resection without hepatotomy or inflow occlusion." Journal of the American College of Surgeons.. 2008 Feb 0; 206(2):390-6. Epub 2007 Sep 20.

2008
Fialkowski EA; Winslow ER; Scott MG; Hawkins WG; Linehan DC; Strasberg SM. "Establishing 'normal' values for liver function tests after reconstruction of biliary injuries". American College of Surgeons. 2008; 207(5): 707-9.

2008
Finkelstein SE, Fernandez FG, Dehdashti F, Siegel BA, Hawkins WG, Linehan DC, Strasberg SM. "Unique site- and time-specific patterns of recurrence following resection of colorectal carcinoma hepatic metastases in patients staged by FDG-PET." Journal of hepato-biliary-pancreatic surgery.. 2008 15(5):483-7. Epub 2008 Oct 04.

9/2007
Tan MC, Linehan DC, Hawkins WG, Siegel BA, Strasberg SM. "Chemotherapy-induced normalization of FDG uptake by colorectal liver metastases does not usually indicate complete pathologic response." Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract.. 2007 Sep 0; 11(9):1112-9. Epub 2007 Jul 11.

4/2007
Pierce RA, Spitler JA, Hawkins WG, Strasberg SM, Linehan DC, Halpin VJ, Eagon JC, Brunt LM, Frisella MM, Matthews BD. "Outcomes analysis of laparoscopic resection of pancreatic neoplasms." Surgical endoscopy.. 2007 Apr 0; 21(4):579-86. Epub 2006 Dec 16.

4/2007
Strasberg SM, Linehan DC, Clavien PA, Barkun JS. "Proposal for definition and severity grading of pancreatic anastomosis failure and pancreatic occlusion failure." Surgery.. 2007 Apr 0; 141(4):420-6. Epub 2007 Mar 09.

2/2007
Strasberg SM, Linehan DC, Hawkins WG. "Radical antegrade modular pancreatosplenectomy procedure for adenocarcinoma of the body and tail of the pancreas: ability to obtain negative tangential margins." Journal of the American College of Surgeons.. 2007 Feb 0; 204(2):244-9. Epub 2007 Jan 04.

1/2007
Thaker RI, Matthews BD, Linehan DC, Strasberg SM, Eagon JC, Hawkins WG. "Absorbable mesh reinforcement of a stapled pancreatic transection line reduces the leak rate with distal pancreatectomy." Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract.. 2007 Jan 0; 11(1):59-65.

9/2006
Lin Y, Goedegebuure PS, Tan MC, Gross J, Malone JP, Feng S, Larson J, Phommaly C, Trinkaus K, Townsend RR, Linehan DC. "Proteins associated with disease and clinical course in pancreas cancer: a proteomic analysis of plasma in surgical patients." Journal of proteome research.. 2006 Sep 0; 5(9):2169-76.

9/2006
Viehl CT, Moore TT, Liyanage UK, Frey DM, Ehlers JP, Eberlein TJ, Goedegebuure PS, Linehan DC. "Depletion of CD4+CD25+ regulatory T cells promotes a tumor-specific immune response in pancreas cancer-bearing mice." Annals of surgical oncology.. 2006 Sep 0; 13(9):1252-8. Epub 2006 Sep 03.

2006
Liyanage UK, Goedegebuure PS, Moore TT, Viehl CT, Moo-Young TA, Larson JW, Frey DM, Ehlers JP, Eberlein TJ, Linehan DC. "Increased prevalence of regulatory T cells (Treg) is induced by pancreas adenocarcinoma." Journal of immunotherapy.. 2006 29(4):416-24.

7/2005
Viehl CT, Becker-Hapak M, Lewis JS, Tanaka Y, Liyanage UK, Linehan DC, Eberlein TJ, Goedegebuure PS. "A tat fusion protein-based tumor vaccine for breast cancer." Annals of surgical oncology.. 2005 Jul 0; 12(7):517-25. Epub 2005 May 10.

6/2005
Fernandez FG, Ritter J, Goodwin JW, Linehan DC, Hawkins WG, Strasberg SM. "Effect of steatohepatitis associated with irinotecan or oxaliplatin pretreatment on resectability of hepatic colorectal metastases." Journal of the American College of Surgeons.. 2005 Jun 0; 200(6):845-53.

6/2005
Lin LL, Picus J, Drebin JA, Linehan DC, Solis J, Strasberg SM, Tan B, Thorstad WL, Myerson R. "A phase II study of alternating cycles of split course radiation therapy and gemcitabine chemotherapy for inoperable pancreatic or biliary tract carcinoma." American journal of clinical oncology.. 2005 Jun 0; 28(3):234-41.

3/2005
Hawkins WG, Busam KJ, Ben-Porat L, Panageas KS, Coit DG, Gyorki DE, Linehan DC, Brady MS. "Desmoplastic melanoma: a pathologically and clinically distinct form of cutaneous melanoma." Annals of surgical oncology.. 2005 Mar 0; 12(3):207-13. Epub 2005 Mar 03.

2005
Linehan DC, Goedegebuure PS. "CD25+ CD4+ regulatory T-cells in cancer." Immunologic research.. 2005 32(1-3):155-68.

9/2004
Fernandez FG, Drebin JA, Linehan DC, Dehdashti F, Siegel BA, Strasberg SM. "Five-year survival after resection of hepatic metastases from colorectal cancer in patients screened by positron emission tomography with F-18 fluorodeoxyglucose (FDG-PET)." Annals of surgery.. 2004 Sep 0; 240(3):438-47; discussion 447-50.

4/2004
Topp SA, McClurken M, Lipson D, Upadhya GA, Ritter JH, Linehan D, Strasberg SM. "Saline-linked surface radiofrequency ablation: factors affecting steam popping and depth of injury in the pig liver." Annals of surgery.. 2004 Apr 0; 239(4):518-27.

8/2003
Strasberg SM, Linehan D. "Radiofrequency ablation of liver tumors." Current problems in surgery.. 2003 Aug 0; 40(8):459-98.

5/2003
Strasberg SM, Drebin JA, Linehan D. "Radical antegrade modular pancreatosplenectomy." Surgery.. 2003 May 0; 133(5):521-7.

2/1/2003
Tanaka Y, Dowdy SF, Linehan DC, Eberlein TJ, Goedegebuure PS. "Induction of antigen-specific CTL by recombinant HIV trans-activating fusion protein-pulsed human monocyte-derived dendritic cells." The Journal of immunology : official journal of the American Association of Immunologists.. 2003 Feb 1; 170(3):1291-8.

11/1/2002
Joo HG, Fleming TP, Tanaka Y, Dunn TJ, Linehan DC, Goedegebuure PS, Eberlein TJ. "Human dendritic cells induce tumor-specific apoptosis by soluble factors." International journal of cancer.. 2002 Nov 1; 102(1):20-8.

9/1/2002
Liyanage UK, Moore TT, Joo HG, Tanaka Y, Herrmann V, Doherty G, Drebin JA, Strasberg SM, Eberlein TJ, Goedegebuure PS, Linehan DC. "Prevalence of regulatory T cells is increased in peripheral blood and tumor microenvironment of patients with pancreas or breast adenocarcinoma." The Journal of immunology : official journal of the American Association of Immunologists.. 2002 Sep 1; 169(5):2756-61.

6/2002
Strasberg SM, Drebin JA, Mokadam NA, Green DW, Jones KL, Ehlers JP, Linehan D. "Prospective trial of a blood supply-based technique of pancreaticojejunostomy: effect on anastomotic failure in the Whipple procedure." Journal of the American College of Surgeons.. 2002 Jun 0; 194(6):746-58; discussion 759-60.

1/2002
Vollmer CM, Drebin JA, Middleton WD, Teefey SA, Linehan DC, Soper NJ, Eagon CJ, Strasberg SM. "Utility of staging laparoscopy in subsets of peripancreatic and biliary malignancies." Annals of surgery.. 2002 Jan 0; 235(1):1-7.

2002
Strasberg SM, Drebin JA, Linehan D. "Use of a bipolar vessel-sealing device for parenchymal transection during liver surgery." Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract.. 2002 6(4):569-74.

7/2000
Olson JA, Morris EA, Van Zee KJ, Linehan DC, Borgen PI. "Magnetic resonance imaging facilitates breast conservation for occult breast cancer." Annals of surgical oncology.. 2000 Jul 0; 7(6):411-5.

4/2000
Linehan DC, Lewis JJ, Leung D, Brennan MF. "Influence of biologic factors and anatomic site in completely resected liposarcoma." Journal of clinical oncology : official journal of the American Society of Clinical Oncology.. 2000 Apr 0; 18(8):1637-43.

3/2000
Downey RJ, Rusch V, Hsu FI, Leon L, Venkatraman E, Linehan D, Bains M, van Zee K, Korst R, Ginsberg R. "Chest wall resection for locally recurrent breast cancer: is it worthwhile?" The Journal of thoracic and cardiovascular surgery.. 2000 Mar 0; 119(3):420-8.

3/2000
Linehan DC, Eberlein TJ. "Mechanisms of radiocolloid localization in sentinel node biopsy." Annals of surgical oncology.. 2000 Mar 0; 7(2):77.

2000
Strasberg SM, Dehdashti F, Siegal BA, Drebin JA and Linehan DC. "Survival of patients evaluated by FEG-PET before hepatic resection for metastatic colorectal carcinoma: a prospective database study". Annals of Surgery. 2000; 233(3): 293-299.

4/1999
Linehan DC, Hill AD, Tran KN, Yeung H, Yeh SD, Borgen PI, Cody HS. "Sentinel lymph node biopsy in breast cancer: unfiltered radioisotope is superior to filtered." Journal of the American College of Surgeons.. 1999 Apr 0; 188(4):377-81.

1999
Linehan DC, Bowne WB, Lewis JJ. "Immunotherapeutic approaches to sarcoma." Seminars in surgical oncology.. 1999 17(1):72-7.

1999
Linehan DC, Hill AD, Akhurst T, Yeung H, Yeh SD, Tran KN, Borgen PI, Cody HS. "Intradermal radiocolloid and intraparenchymal blue dye injection optimize sentinel node identification in breast cancer patients." Annals of surgical oncology.. 1999 6(5):450-4.

4/1998
Cady B, Jenkins RL, Steele GD, Lewis WD, Stone MD, McDermott WV, Jessup JM, Bothe A, Lalor P, Lovett EJ, Lavin P, Linehan DC. "Surgical margin in hepatic resection for colorectal metastasis: a critical and improvable determinant of outcome." Annals of surgery.. 1998 Apr 0; 227(4):566-71.

5/1997
Peiper M, Goedegebuure PS, Linehan DC, Ganguly E, Douville CC, Eberlein TJ. "The HER2/neu-derived peptide p654-662 is a tumor-associated antigen in human pancreatic cancer recognized by cytotoxic T lymphocytes." European journal of immunology.. 1997 May 0; 27(5):1115-23.

2/1/1997
Goedegebuure PS, Douville CC, Doherty JM, Linehan DC, Lee KY, Ganguly EK, Eberlein TJ. "Simultaneous production of T helper-1-like cytokines and cytolytic activity by tumor-specific T cells in ovarian and breast cancer." Cellular immunology.. 1997 Feb 1; 175(2):150-6.

3/1996
Linehan DC, Goedegebuure PS, Eberlein TJ. "Vaccine therapy for cancer." Annals of surgical oncology.. 1996 Mar 0; 3(2):219-28.

11/1/1995
Linehan DC, Goedegebuure PS, Peoples GE, Rogers SO, Eberlein TJ. "Tumor-specific and HLA-A2-restricted cytolysis by tumor-associated lymphocytes in human metastatic breast cancer." The Journal of immunology : official journal of the American Association of Immunologists.. 1995 Nov 1; 155(9):4486-91.

9/1995
Peoples GE, Smith RC, Linehan DC, Yoshino I, Goedegebuure PS, Eberlein TJ. "Shared T cell epitopes in epithelial tumors." Cellular immunology.. 1995 Sep 0; 164(2):279-86.

4/1995
Lee KY, Goedegebuure PS, Linehan DC, Eberlein TJ. "Immunoregulatory effects of CD4+ T helper subsets in human melanoma." Surgery.. 1995 Apr 0; 117(4):365-72.

2/1995
Linehan DC, Peoples GE, Hess DT, Summerhayes IC, Parikh AS, Goedegebuure PS, Eberlein TJ. "In vitro stimulation of ovarian tumour-associated lymphocytes with a peptide derived from HER2/neu induces cytotoxicity against autologous tumour." Surgical oncology.. 1995 Feb 0; 4(1):41-9.

1/17/1995
Peoples GE, Goedegebuure PS, Smith R, Linehan DC, Yoshino I, Eberlein TJ. "Breast and ovarian cancer-specific cytotoxic T lymphocytes recognize the same HER2/neu-derived peptide." Proceedings of the National Academy of Sciences of the United States of America.. 1995 Jan 17; 92(2):432-6.

1995
Linehan DC; Goedegebuure PS; Peoples GE; Eberlein TJ. "T-cells isolated from breast cancer patients recognize a HER2/neu derived tumor-associated antigen shared by several epithelial-based tumors". Surgical Forum. 1995; 46: 496-498.

1995
Peiper M; Linehan DC; Ganguly E; Douville C; Goedegebuure PS; Eberlein TJ. "Lysis of pancreatic cancer cells by tumor-specific T-cells is associated with tumor cell expression of HER2/neu". 1995; 46: 140-142.

1994
Peoples GE; Smith RC; Linehan DC; Goedegebuure PS; Eberlein TJ. "Ovarian and breast cancer express shared antigenic peptides recognized by tumor-specific cytotoxic T-lymphocytes". Surgical Forum. 1994; 45: 565-567.

1994
Linehan DC; Peoples GE; Parikh AS; Goedegebuure PS; Eberlein TJ. "Ovarian and breast tumor-associated lymphocytes stimulated with an antigenic peptide derived from HER2/neu show enhanced cytotoxicity against autologous tumor". Surgical Forum. 1994; 45: 568-570.

Books & Chapters

2007
Book Title: Surgery of the Liver, Biliary Tract and Pancreas
Author List: Linehan DC and Jarnagin WR
Edited By: Blumgart LH, Editor-in-Chief
Published By: Elsevier2007 in Philadelphia

2002
Chapter Title: Thermal Ablation of Liver Tumors by Radiofrequency, Microwave, and Laser Therapy
Book Title: Malignant Liver Tumors: Current and Emerging Therapies
Author List: Strasberg SM and Linehan DC
Published By: Bartlett and Barnes2002 in Chicago

2001
Chapter Title: Active Immunotherapy
Book Title: Surgical Research
Author List: Linehan DC; Amos K; Eberlein TJ
Edited By: Souba WW and Wilmore, DW
Published By: Academic Press2001 in San Diego, CA

2001
Chapter Title: Soft Tissue Sarcoma
Book Title: Surgical Treatment: Evidence-Based and Problem Oriented
Author List: Linehan DC and Brennan MF
Edited By: Holzheimer RG and Mannick JA
Published By: W Zuckschwerdt Verlag2001 in Munch