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Ruchira Singh, Ph.D.


Showing all 17 journal articles & 0 books available

Journal Articles

Gamm DM, Clark E, Capowski EE, Singh R. "The Role of FGF9 In The Production of Neural Retina And RPE In A Pluripotent Stem Cell Model of Early Human Retinal Development." American journal of ophthalmology.. 2019 May 10; Epub 2019 May 10.

Anand-Apte B, Chao JR, Singh R, Stöhr H. "Sorsby fundus dystrophy: Insights from the past and looking to the future." Journal of neuroscience research.. 2019 Jan 0; 97(1):88-97. Epub 2018 Aug 21.

Dalvi S, Galloway CA, Winschel L, Hashim A, Soto C, Tang C, MacDonald LA, Singh R. "Environmental stress impairs photoreceptor outer segment (POS) phagocytosis and degradation and induces autofluorescent material accumulation in hiPSC-RPE cells." Cell death discovery.. 2019 5:96. Epub 2019 May 16.

Dalvi S, Galloway CA, Singh R. "Pluripotent Stem Cells to Model Degenerative Retinal Diseases: The RPE Perspective." Advances in experimental medicine and biology.. 2019 1186:1-31.

Galloway CA, Dalvi S, Shadforth AMA, Suzuki S, Wilson M, Kuai D, Hashim A, MacDonald LA, Gamm DM, Harkin DG, Singh R. "Characterization of Human iPSC-RPE on a Prosthetic Bruch's Membrane Manufactured From Silk Fibroin." Investigative ophthalmology & visual science.. 2018 Jun 1; 59(7):2792-2800.

Galloway CA, Dalvi S, Hung SSC, MacDonald LA, Latchney LR, Wong RCB, Guymer RH, Mackey DA, Williams DS, Chung MM, Gamm DM, Pébay A, Hewitt AW, Singh R. "Drusen in patient-derived hiPSC-RPE models of macular dystrophies." Proceedings of the National Academy of Sciences of the United States of America.. 2017 Sep 26; 114(39):E8214-E8223. Epub 2017 Sep 06.

Singh R, Kuai D, Guziewicz KE, Meyer J, Wilson M, Lu J, Smith M, Clark E, Verhoeven A, Aguirre GD, Gamm DM. "Pharmacological Modulation of Photoreceptor Outer Segment Degradation in a Human iPS Cell Model of Inherited Macular Degeneration." Molecular therapy : the journal of the American Society of Gene Therapy.. 2015 Nov 0; 23(11):1700-1711. Epub 2015 Aug 24.

Phillips MJ, Perez ET, Martin JM, Reshel ST, Wallace KA, Capowski EE, Singh R, Wright LS, Clark EM, Barney PM, Stewart R, Dickerson SJ, Miller MJ, Percin EF, Thomson JA, Gamm DM. "Modeling human retinal development with patient-specific induced pluripotent stem cells reveals multiple roles for visual system homeobox 2." Stem cells.. 2014 Jun 0; 32(6):1480-92.

Singh R, Phillips MJ, Kuai D, Meyer J, Martin JM, Smith MA, Perez ET, Shen W, Wallace KA, Capowski EE, Wright LS, Gamm DM. "Functional analysis of serially expanded human iPS cell-derived RPE cultures." Investigative ophthalmology & visual science.. 2013 Oct 17; 54(10):6767-78. Epub 2013 Oct 17.

McDowell TS, Wang ZY, Singh R, Bjorling D. "CB1 cannabinoid receptor agonist prevents NGF-induced sensitization of TRPV1 in sensory neurons." Neuroscience letters.. 2013 Sep 13; 551:34-8. Epub 2013 Jul 12.

Gamm DM, Phillips MJ, Singh R. "Modeling retinal degenerative diseases with human iPS-derived cells: current status and future implications." Expert review of ophthalmology.. 2013 Jun 1; 8(3):213-216.

Singh R, Shen W, Kuai D, Martin JM, Guo X, Smith MA, Perez ET, Phillips MJ, Simonett JM, Wallace KA, Verhoeven AD, Capowski EE, Zhang X, Yin Y, Halbach PJ, Fishman GA, Wright LS, Pattnaik BR, Gamm DM. "iPS cell modeling of Best disease: insights into the pathophysiology of an inherited macular degeneration." Human molecular genetics.. 2013 Feb 1; 22(3):593-607. Epub 2012 Nov 08.

Yamauchi D, Nakaya K, Raveendran NN, Harbidge DG, Singh R, Wangemann P, Marcus DC. "Expression of epithelial calcium transport system in rat cochlea and vestibular labyrinth." BMC physiology. 2010 Jan 29; 10:1. Epub 2010 Jan 29.

Wangemann P, Kim HM, Billings S, Nakaya K, Li X, Singh R, Sharlin DS, Forrest D, Marcus DC, Fong P. "Developmental delays consistent with cochlear hypothyroidism contribute to failure to develop hearing in mice lacking Slc26a4/pendrin expression." American journal of physiology. Renal physiology.. 2009 Nov 0; 297(5):F1435-47. Epub 2009 Aug 19.

Singh R, Wangemann P. "Free radical stress-mediated loss of Kcnj10 protein expression in stria vascularis contributes to deafness in Pendred syndrome mouse model." American journal of physiology. Renal physiology.. 2008 Jan 0; 294(1):F139-48. Epub 2007 Oct 24.

Jabba SV, Oelke A, Singh R, Maganti RJ, Fleming S, Wall SM, Everett LA, Green ED, Wangemann P. "Macrophage invasion contributes to degeneration of stria vascularis in Pendred syndrome mouse model." BMC medicine.. 2006 Dec 22; 4:37. Epub 2006 Dec 22.

Singh R, Maganti RJ, Jabba SV, Wang M, Deng G, Heath JD, Kurn N, Wangemann P. "Microarray-based comparison of three amplification methods for nanogram amounts of total RNA." American journal of physiology. Cell physiology.. 2005 May 0; 288(5):C1179-89. Epub 2004 Dec 21.