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Constantinos Ketonis, M.D., Ph.D.

Contact Information

Phone Numbers

Appointment: (585) 275-5321

Administrative: (585) 275-6970

Fax: (585) 273-3297

URMFGA member of the University of Rochester Medical Faculty Group

groupAn Accountable Health Partner

assignmentAccepting New Patients

Faculty Appointments

Patient Care Setting

Orthopaedics & Physical Performance


Dr. Ketonis specializes in the treatment of hand, wrist, elbow, and shoulder problems. He treats all aspects of hand/wrist, shoulder/elbow, degenerative conditions such as arthritis, reconstruction, as well as peripheral nerve pathologies. His clinical interests include joint arthroplasty, arthroscopic treatment of hand and upper extremity problems including the rotator cuff of the shoulder, minimally invasive endoscopic procedures as well as microsurgery.

Dr. Ketonis earned his M.D. from Sidney Kimmel Medical College at Thomas Jefferson University, where he was also awarded a Ph.D. in tissue engineering and regenerative medicine for his work on antimicrobial modification of orthopaedic implants. He completed his orthopaedic surgery training at The Rothman Institute in Philadelphia and went on to complete a fellowship in upper extremity/ hand surgery and microsurgery at the prestigious Curtis National Hand Center in Baltimore.

In addition, he has served as an Officer in the Cypriot National Guard and in Special Forces Training with the Green Berets. He has also been a martial arts instructor and won awards at national competitions.


Dr Ketonis continues to utilize his background in basic science and clinical research to advance the field of orthopedics. He has authored numerous publications and book chapters on topics related to hand surgery, prosthetics, infection and bone grafts, and he frequently presents at the national and international levels. Dr. Ketonis is the recipient of several prestigious awards and honors, as well as research grants. He also holds U.S. Patents on implant modification technologies, as well as novel 3D-printed devices that he designed to address hand conditions.

Remaining heavily involved in research, his newest endeavors include utilization of Artificial Intelligence and Machine Learning in the interpretation of medical imaging, automated ultrasound evaluation of scar formation on tendons and also is investigating the mechanisms of infection establishment on biological tissues.



  • Orthopaedic Surgery


MD, PhD | Jefferson Medical College

Post-doctoral Training & Residency

08/01/2016 - 07/31/2017
Fellowship in Hand Surgery at MedStar Union Memorial Hospital - Curtis National Hand Center

06/01/2012 - 06/30/2016
Residency in Orthopaedic Surgery at Thomas Jefferson University Hospital

06/01/2011 - 06/30/2012
Internship in Orthopaedic Surgery at Thomas Jefferson University Hospital

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Eastern Orthopaedic Association Founders' Award- Top Paper

The William W. Bodine, Jr. Prize

The Robert J. Mandle Memorial Graduation Award

The MD/PhD Thesis Price for Innovations in Translational Research

International Society for Technology in Arthroplasty HAP Paul Award

Eastern Orthopaedic Association Founders' Award

Sigma Xi Research Day Poster Competition

2008 - 2009
MTF (Musculoskeletal Transplant Foundation) Grant recipient

J.R Neff Award

Rutgers Research Fellow Award

Samuel Welkowitz Award

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Journal Articles

Best KT, Nichols AEC, Knapp E, Hammert WC, Ketonis C, Jonason JH, Awad HA, Loiselle AE. "NF-?B activation persists into the remodeling phase of tendon healing and promotes myofibroblast survival." Science signaling.. 2020 Nov 17; 13(658)Epub 2020 Nov 17.

Myers TG, Ramkumar PN, Ricciardi BF, Urish KL, Kipper J, Ketonis C. "Artificial Intelligence and Orthopaedics: An Introduction for Clinicians." The Journal of bone and joint surgery. American volume.. 2020 May 6; 102(9):830-840.

Ketonis C, Kipper J, Urish KL, Ricciardi BF, Ramkumar PN, Myers TG. "Artificial Intelligence and Orthopaedics: An Introduction for Clinicians." The Journal of bone and joint surgery. American volume.. 2020 Feb 6; Epub 2020 Feb 06.

Books & Chapters

Chapter Title: The Human Meniscus
Book Title: The Knee: Reconstruction, Replacement, and Revision
Author List: Javad Parvizi
Published By: Data Trace Publishing Company 2012

Chapter Title: Tethered Antibiotics
Book Title: Comprehensive Biomaterials (1st ed.)
Author List: Paul Ducheyne, Kevin Healy, Dietmar W. Hutmacher, David W. Grainger, C. James Kirkpatrick
Published By: Elsevier Press 2011

Chapter Title: Antimicrobial implants and bone allografts: new uses for old antibiotics
Book Title: Volume # 3: Science against microbial pathogens: communicating current research and technological advances
Author List: A. Mendez-Vilas
Published By: Formatex Research Center 2011




Constantinos Ketonis, M.D., Ph.D.