Skip to main content
Explore URMC

Constantinos Ketonis, M.D., Ph.D.

Contact Information

Phone Numbers

Appointment: (585) 275-5321

Administrative: (585) 275-6970

Fax: (585) 273-3297

URMFGA member of the University of Rochester Medical Faculty Group

groupAn Accountable Health Partner

assignmentAccepting New Patients

Faculty Appointments

Patient Care Setting

Orthopaedics & Physical Performance


I specialize in the treatment of hand, wrist, elbow, and shoulder problems. I treat all aspects of hand/wrist, shoulder/elbow, degenerative conditions such as arthritis, reconstruction, as well as peripheral nerve pathologies. My clinical interests includes joint arthroplasty, arthroscopic treatment of hand and upper extremity problems including the rotator cuff of the shoulder, minimally invasive endoscopic procedures as well as microsurgery.

I have served as an Officer in the Cypriot National Guard and in Special Forces Training with the Green Berets. I have also been a martial arts instructor and won awards at national competitions.


I continue to utilize my background in basic science and clinical research to advance the field of orthopedics. I have authored numerous publications and book chapters on topics related to hand surgery, prosthetics, infection and bone grafts, and I frequently present at the national and international levels. I am the recipient of several prestigious awards and honors, as well as research grants. I hold U.S. Patents on implant modification technologies, as well as novel 3D-printed devices that I designed to address hand conditions.

Remaining heavily involved in research, my newest endeavors include utilization of Artificial Intelligence and Machine Learning in the interpretation of medical imaging, automated ultrasound evaluation of scar formation on tendons and I am also investigating the mechanisms of infection establishment on biological tissues.




    MD | Jefferson Medical College

    Post-doctoral Training & Residency

    08/01/2016 - 07/31/2017
    Fellowship in Hand Surgery at MedStar Union Memorial Hospital at Baltimore

    06/01/2012 - 06/30/2016
    Residency in Orthopaedic Surgery at Thomas Jefferson University Hospital

    06/01/2011 - 06/30/2012
    Internship in Orthopaedic Surgery at Thomas Jefferson University Hospital

    VIEW ALL expand_more


    Eastern Orthopaedic Association Founders' Award- Top Paper

    The William W. Bodine, Jr. Prize

    The Robert J. Mandle Memorial Graduation Award

    The MD/PhD Thesis Price for Innovations in Translational Research

    International Society for Technology in Arthroplasty HAP Paul Award

    Eastern Orthopaedic Association Founders' Award

    Sigma Xi Research Day Poster Competition

    2008 - 2009
    MTF (Musculoskeletal Transplant Foundation) Grant recipient

    J.R Neff Award

    Rutgers Research Fellow Award

    Samuel Welkowitz Award

    VIEW ALL expand_more


    Journal Articles

    Nichols AEC, Wagner NW, Ketonis C, Loiselle AE. "Epitenon-derived cells comprise a distinct progenitor population that contributes to both tendon fibrosis and regeneration following acute injury." bioRxiv : the preprint server for biology.. 2023 Feb 1; Epub 2023 Feb 01.

    Best KT, Nichols AEC, Knapp E, Hammert WC, Ketonis C, Jonason JH, Awad HA, Loiselle AE. "NF-?B activation persists into the remodeling phase of tendon healing and promotes myofibroblast survival." Science signaling.. 2020 Nov 17; 13(658)Epub 2020 Nov 17.

    Myers TG, Ramkumar PN, Ricciardi BF, Urish KL, Kipper J, Ketonis C. "Artificial Intelligence and Orthopaedics: An Introduction for Clinicians." The Journal of bone and joint surgery. American volume.. 2020 May 6; 102(9):830-840.

    Books & Chapters

    Chapter Title: The Human Meniscus
    Book Title: The Knee: Reconstruction, Replacement, and Revision
    Author List: Javad Parvizi
    Published By: Data Trace Publishing Company 2012

    Chapter Title: Tethered Antibiotics
    Book Title: Comprehensive Biomaterials (1st ed.)
    Author List: Paul Ducheyne, Kevin Healy, Dietmar W. Hutmacher, David W. Grainger, C. James Kirkpatrick
    Published By: Elsevier Press 2011

    Chapter Title: Antimicrobial implants and bone allografts: new uses for old antibiotics
    Book Title: Volume # 3: Science against microbial pathogens: communicating current research and technological advances
    Author List: A. Mendez-Vilas
    Published By: Formatex Research Center 2011




    Constantinos Ketonis, M.D., Ph.D.