I specialize in the treatment of hand, wrist, elbow, and shoulder problems. I treat all aspects of hand/wrist, shoulder/elbow, degenerative conditions such as arthritis, reconstruction, as well as peripheral nerve pathologies. My clinical interests includes joint arthroplasty, arthroscopic treatment of hand and upper extremity problems including the rotator cuff of the shoulder, minimally invasive endoscopic procedures as well as microsurgery.

I have served as an Officer in the Cypriot National Guard and in Special Forces Training with the Green Berets. I have also been a martial arts instructor and won awards at national competitions.

Certified Specialties

Orthopaedic Surgery - American Board of Orthopaedic Surgery

Surgery of the Hand - American Board of Orthopaedic Surgery

Faculty Appointments

Associate Professor - Department of Orthopaedics (SMD)

Credentials

Residency & Fellowship

Fellowship, Hand Surgery, MedStar Union Memorial Hospital at Baltimore. 2016 - 2017

Residency, Orthopaedic Surgery, Thomas Jefferson University Hospital. 2012 - 2016

Internship, Orthopaedic Surgery, Thomas Jefferson University Hospital. 2011 - 2012

Education

MD | Jefferson Medical College. 2011

Awards

Eastern Orthopaedic Association Founders' Award- Top Paper. 2015

The William W. Bodine, Jr. Prize. 2011

The Robert J. Mandle Memorial Graduation Award. 2011

The MD/PhD Thesis Price for Innovations in Translational Research. 2011

International Society for Technology in Arthroplasty HAP Paul Award. 2009

Eastern Orthopaedic Association Founders' Award. 2009

Sigma Xi Research Day Poster Competition. 2009

MTF (Musculoskeletal Transplant Foundation) Grant recipient. 2008 - 2009

J.R Neff Award. 2007

Rutgers Research Fellow Award. 2004

Samuel Welkowitz Award. 2004

Research

I continue to utilize my background in basic science and clinical research to advance the field of orthopedics. I have authored numerous publications and book chapters on topics related to hand surgery, prosthetics, infection and bone grafts, and I frequently present at the national and international levels. I am the recipient of several prestigious awards and honors, as well as research grants. I hold U.S. Patents on implant modification technologies, as well as novel 3D-printed devices that I designed to address hand conditions.

Remaining heavily involved in research, my newest endeavors include utilization of Artificial Intelligence and Machine Learning in the interpretation of medical imaging, automated ultrasound evaluation of scar formation on tendons and I am also investigating the mechanisms of infection establishment on biological tissues.

Publications

Journal Articles

Diagnosis of Ulnar Neuropathy at the Elbow Using Ultrasound-A Comparison to Electrophysiologic Studies.

Carroll TJ, Chirokikh A, Thon J, Jones CMC, Logigian E, Ketonis C

The Journal of hand surgery.. 2023 October 23 Epub 10/23/2023.

A Multicenter Prospective Randomized Comparison of Conduits Versus Decellularized Nerve Allograft for Digital Nerve Repairs.

Isaacs J, Nydick JA, Means KR, Merrell GA, Ilyas A, Levin LS,

The Journal of hand surgery.. 2023 September 48 (9):904-913. Epub 08/02/2023.

Association of Patient-Reported Outcomes Measurement Information System Measures with Injection and Surgical Treatment Response in Patients with De Quervain Tenosynovitis.

Smolyak G, Qiu B, Cora Jones CM, Ketonis C

The Journal of hand surgery.. 2023 August 14 Epub 08/14/2023.

Ultrasound Assessment of the Ulnar Nerve Around the Elbow and Diagnosis of Cubital Tunnel Syndrome, Clinical Outcomes.

Catanzaro M, Santangelo G, Speach D, Ketonis C

Hand : official journal of the American Association for Hand Surgery.. 2023 August 3 :15589447231187081. Epub 08/03/2023.

Epitenon-derived cells comprise a distinct progenitor population that contributes to both tendon fibrosis and regeneration following acute injury.

Nichols AEC, Wagner NW, Ketonis C, Loiselle AE

bioRxiv : the preprint server for biology.. 2023 February 1 Epub 02/01/2023.

NF-?B activation persists into the remodeling phase of tendon healing and promotes myofibroblast survival.

Best KT, Nichols AEC, Knapp E, Hammert WC, Ketonis C, Jonason JH, Awad HA, Loiselle AE

Science signaling.. 2020 November 1713 (658)Epub 11/17/2020.

Artificial Intelligence and Orthopaedics: An Introduction for Clinicians.

Myers TG, Ramkumar PN, Ricciardi BF, Urish KL, Kipper J, Ketonis C

The Journal of bone and joint surgery. American volume.. 2020 May 6102 (9):830-840. Epub 1900 01 01.

Artificial Intelligence and Orthopaedics: An Introduction for Clinicians.

Ketonis C, Kipper J, Urish KL, Ricciardi BF, Ramkumar PN, Myers TG

The Journal of bone and joint surgery. American volume.. 2020 February 6 Epub 02/06/2020.

Erratum to 'General Assembly, Prevention, Antiseptic Irrigation Solution: Proceedings of International Consensus on Orthopedic Infections' [The Journal of Arthroplasty 34 (2019) S131-S138].

Blom A, Cho J, Fleischman A, Goswami K, Ketonis C, Kunutsor SK, Makar G, Meeker DG, Morgan-Jones R, Ortega-Peña S, Parvizi J, Smeltzer M, Stambough JB, Urish K, Ziliotto G

The Journal of arthroplasty.. 2019 June 34 (6):1299. Epub 03/28/2019.

Hip and Knee Section, Prevention, Prosthesis Factors: Proceedings of International Consensus on Orthopedic Infections.

Aboltins CA, Antoci V, Bhattacharyya S, Cross M, Ducheyne P, Freiberg AA, Hailer N, Kay P, Ketonis C, Klement MR, Köse N, Lee M, Mitchell P, Nandi S, Palacio Villegas JC, Perry K, Prieto H, Shahi A, Trebše R, Turner D, Wu CT, Yazdi H

The Journal of arthroplasty.. 2018 October 19 Epub 10/19/2018.

General Assembly, Prevention, Antiseptic Irrigation Solution: Proceedings of International Consensus on Orthopedic Infections.

Blom A, Cho J, Fleischman A, Goswami K, Ketonis C, Kunustor S, Makar G, Meeker DG, Morgan-Jones R, Ortega-Peña S, Parvizi J, Smeltzer M, Stambough JB, Urish K, Tonelo Zilotto GP

The Journal of arthroplasty.. 2018 October 19 Epub 10/19/2018.

Neurolysis with Amniotic Membrane Nerve Wrapping for Treatment of Secondary Wartenberg Syndrome: A Preliminary Report.

Gaspar MP, Kane PM, Vosbikian MM, Ketonis C, Rekant MS

The journal of hand surgery Asian-Pacific volume.. 2017 June 22 (2):222-228. Epub 1900 01 01.

Timing of Debridement and Infection Rates in Open Fractures of the Hand: A Systematic Review.

Ketonis C, Dwyer J, Ilyas AM

Hand : official journal of the American Association for Hand Surgery.. 2017 March 12 (2):119-126. Epub 07/08/2016.

Reduction Loss After Distal Radius Fracture Fixation With Locked Volar Plates.

Vosbikian MM, Ketonis C, Huang R, Costanzo JA, Ilyas AM

Journal of surgical orthopaedic advances.. 2017 26 (3):160-165. Epub 1900 01 01.

Wide Awake Trigger Finger Release Surgery: Prospective Comparison of Lidocaine, Marcaine, and Exparel.

Ketonis C, Kim N, Liss F, Zmistowski B, Matzon J, Leinberry C, Wang M, Jones C, Abboudi J, Kirkpatrick W, Ilyas AM

Hand : official journal of the American Association for Hand Surgery.. 2016 June 11 (2):177-83. Epub 03/08/2016.

Optimal Positioning for Volar Plate Fixation of a Distal Radius Fracture: Determining the Distal Dorsal Cortical Distance.

Vosbikian MM, Ketonis C, Huang R, Ilyas AM

The Orthopedic clinics of North America.. 2016 January 47 (1):235-44. Epub 1900 01 01.

Pain management strategies in hand surgery.

Ketonis C, Ilyas AM, Liss F

The Orthopedic clinics of North America.. 2015 July 46 (3):399-408, xi. Epub 03/31/2015.

Staphylococcal persistence due to biofilm formation in synovial fluid containing prophylactic cefazolin.

Dastgheyb SS, Hammoud S, Ketonis C, Liu AY, Fitzgerald K, Parvizi J, Purtill J, Ciccotti M, Shapiro IM, Otto M, Hickok NJ

Antimicrobial agents and chemotherapy.. 2015 April 59 (4):2122-8. Epub 01/26/2015.

Prosthesis selection.

Diaz-Ledezma C, Parvizi J, Zhou Y, Antoci V, Ducheyne P, Freiberg A, Garcia Rangel G, Han SB, Hickok N, Higuera C, Ketonis C, Korkusuz F, Kruczynski J, Macule F, Markuszewski J, Marín-Peña O, Nathwani D, Noble P, Ong K, Ono N, Parvizi MS, Post Z, Rivero-Boschert S, Schaer T, Shapiro I

The Journal of arthroplasty.. 2014 February 29 (2 Suppl):71-6. Epub 12/17/2013.

Prosthesis selection.

Diaz-Ledezma C, Parvizi J, Zhou Y, Antoci V, Ducheyne P, Freiberg A, Rangel GG, Han SB, Hickok N, Higuera C, Ketonis C, Korkusuz F, Kruczynski J, Macule F, Markuszewski J, Marín-Peña O, Nathwani D, Noble P, Ong K, Ono N, Parvizi MS, Post Z, Rivero-Boschert S, Schaer T, Shapiro I

Journal of orthopaedic research : official publication of the Orthopaedic Research Society.. 2014 January 32 Suppl 1 :S90-7. Epub 1900 01 01.

Evolving strategies to prevent implant-associated infections.

Ketonis C, Parvizi J, Jones LC

The Journal of the American Academy of Orthopaedic Surgeons.. 2012 July 20 (7):478-80. Epub 1900 01 01.

Antibacterial activity of bone allografts: comparison of a new vancomycin-tethered allograft with allograft loaded with adsorbed vancomycin.

Ketonis C, Barr S, Shapiro IM, Parvizi J, Adams CS, Hickok NJ

Bone.. 2011 March 148 (3):631-8. Epub 10/28/2010.

Vancomycin bonded to bone grafts prevents bacterial colonization.

Ketonis C, Barr S, Adams CS, Shapiro IM, Parvizi J, Hickok NJ

Antimicrobial agents and chemotherapy.. 2011 February 55 (2):487-94. Epub 11/22/2010.

Bacterial colonization of bone allografts: establishment and effects of antibiotics.

Ketonis C, Barr S, Adams CS, Hickok NJ, Parvizi J

Clinical orthopaedics and related research.. 2010 August 468 (8):2113-21. Epub 1900 01 01.

Antibiotic modification of native grafts: improving upon nature's scaffolds.

Ketonis C, Adams CS, Barr S, Aiyer A, Shapiro IM, Parvizi J, Hickok NJ

Tissue engineering. Part A.. 2010 June 16 (6):2041-9. Epub 1900 01 01.

Topographic features retained after antibiotic modification of Ti alloy surfaces: retention of topography with attachment of antibiotics.

Ketonis C, Parvizi J, Adams CS, Shapiro IM, Hickok NJ

Clinical orthopaedics and related research.. 2009 July 467 (7):1678-87. Epub 04/14/2009.

Periprosthetic infection: where do we stand with regard to Gram stain?

Ghanem E, Ketonis C, Restrepo C, Joshi A, Barrack R, Parvizi J

Acta orthopaedica.. 2009 February 80 (1):37-40. Epub 1900 01 01.

Books

The Knee: Reconstruction, Replacement, and Revision (2012)

Chapter: The Human Meniscus

Authors: Javad Parvizi

Publisher: Data Trace Publishing Company 2012

Comprehensive Biomaterials (1st ed.) (2011)

Chapter: Tethered Antibiotics

Authors: Paul Ducheyne, Kevin Healy, Dietmar W. Hutmacher, David W. Grainger, C. James Kirkpatrick

Publisher: Elsevier Press 2011

Volume # 3: Science against microbial pathogens: communicating current research and technological advances (2011)

Chapter: Antimicrobial implants and bone allografts: new uses for old antibiotics

Authors: A. Mendez-Vilas

Publisher: Formatex Research Center 2011

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