Dr. Bohjanen joined the faculty at URMC in May of 2022 as the Chief of the Infectious Diseases Division in the Department of Medicine. He is a Professor in the Department of Medicine with joint appointments in the Department of Microbiology and Immunology and the Department of Public Health Sciences. Dr. Bohjanen graduated from the University of Michigan with an MD, PhD degree in 1993. He then completed an internal medicine residency in 1997 and an infectious diseases fellowship in 2000, both at Duke University. Dr. Bohjanen was a faculty member at the University of Minnesota from 2000 until he joined URMC. At the University of Minnesota, Dr. Bohjanen served in leadership positions that included Director of the Center for Infectious Diseases and Microbiology Translational Research, Program Director of the Infectious Diseases Fellowship Program, and Director of the Division of Infectious Diseases and International Research. Dr. Bohjanen is a physician-scientist with a clinical interest in HIV infection and the global AIDS epidemic, and his laboratory research is directed at understanding the regulation of gene expression in human diseases, including HIV infection and cancer. Over the past 19 years, he has developed a multidisciplinary collaborative international research program in Uganda that has involved clinical research focused on improving outcomes for patients with AIDS, as well as studies of disease pathogenesis in his laboratory using samples collected from patients in Uganda.

Faculty Appointments

Professor - Department of Medicine, Infectious Diseases (SMD)

Chief - Department of Medicine, Infectious Diseases (SMD)

Credentials

Residency & Fellowship

Fellowship, Infectious Disease, Duke University. 1997 - 2000

Residency, Internal Medicine, Duke University. 1994 - 1997

Internship, Internal Medicine, Duke University. 1993 - 1994

Education

MD | University of Michigan Medical School. 1993

Publications

Journal Articles

High Burden of Cryptococcal Meningitis Among Antiretroviral Therapy-Experienced Human Immunodeficiency Virus-Infected Patients in Northern Uganda in the Era of "Test and Treat": Implications for Cryptococcal Screening Programs.

Okwir M, Link A, Rhein J, Obbo JS, Okello J, Nabongo B, Alal J, Meya D, Bohjanen PR

Open forum infectious diseases.. 2022 February 9 (2):ofac004. Epub 01/10/2022.

Delays in Cryptococcal Meningitis Diagnosis and Care: A Mixed Methods Study in Rural Uganda.

Link A, Okwir M, Nabongo B, Meya D, Iribarren S, Bohjanen P, Kasprzyk D

Annals of global health.. 2022 88 (1):22. Epub 03/18/2022.

Neuromyelitis Optica Spectrum Disorders in Africa: A Systematic Review.

Musubire AK, Derdelinckx J, Reynders T, Meya DB, Bohjanen PR, Cras P, Willekens B

Neurology® neuroimmunology & neuroinflammation.. 2021 November 8 (6)Epub 10/18/2021.

Transcriptomic biomarker pathways associated with death in HIV-infected patients with cryptococcal meningitis.

Vlasova-St Louis I, Musubire AK, Meya DB, Nabeta HW, Mohei H, Boulware DR, Bohjanen PR

BMC medical genomics.. 2021 April 1614 (1):108. Epub 04/16/2021.

The hepatitis C viral nonstructural protein 5A stabilizes growth-regulatory human transcripts.

Guo L, Sharma SD, Debes JD, Beisang D, Rattenbacher B, Louis IV, Wiesner DL, Cameron CE, Bohjanen PR

Nucleic acids research.. 2020 February 2048 (3):1599. Epub 1900 01 01.

B Cell Compartmentalization in Blood and Cerebrospinal Fluid of HIV-Infected Ugandans with Cryptococcal Meningitis.

Okurut S, Meya DB, Bwanga F, Olobo J, Eller MA, Cham-Jallow F, Bohjanen PR, Pratap H, Palmer BE, Hullsiek KH, Manabe YC, Boulware DR, Janoff EN

Infection and immunity.. 2020 February 2088 (3)Epub 02/20/2020.

Epidemiology of non-traumatic spinal cord injury in Uganda: a single center, prospective study with MRI evaluation.

Musubire AK, Meya DB, Katabira ET, Meyer ACL, Bohjanen PR, Boulware DR, Minja F

BMC neurology.. 2019 January 1519 (1):10. Epub 01/15/2019.

Transcriptomic Predictors of Paradoxical Cryptococcosis-Associated Immune Reconstitution Inflammatory Syndrome.

Vlasova-St Louis I, Chang CC, Shahid S, French MA, Bohjanen PR

Open forum infectious diseases.. 2018 July 5 (7):ofy157. Epub 07/02/2018.

The hepatitis C viral nonstructural protein 5A stabilizes growth-regulatory human transcripts.

Guo L, Sharma SD, Debes JD, Beisang D, Rattenbacher B, Vlasova-St Louis I, Wiesner DL, Cameron CE, Bohjanen PR

Nucleic acids research.. 2018 March 1646 (5):2537-2547. Epub 1900 01 01.

Viral manipulation of host mRNA decay.

Guo L, Vlasova-St Louis I, Bohjanen PR

Future virology.. 2018 March 13 (3):211-223. Epub 02/23/2018.

Reovirus infection induces stabilization and up-regulation of cellular transcripts that encode regulators of TGF-? signaling.

Guo L, Smith JA, Abelson M, Vlasova-St Louis I, Schiff LA, Bohjanen PR

PloS one.. 2018 13 (9):e0204622. Epub 09/27/2018.

Post-transcriptional regulation of cytokine expression and signaling.

Guo L, Louis IV, Bohjanen PR

Current trends in immunology.. 2018 19 :33-40. Epub 1900 01 01.

Blood neutrophil counts in HIV-infected patients with cryptococcal meningitis: Association with mortality.

Musubire AK, Meya DB, Rhein J, Meintjes G, Bohjanen PR, Nuwagira E, Muzoora C, Boulware DR, Hullsiek KH,

PloS one.. 2018 13 (12):e0209337. Epub 12/31/2018.

Neurocognitive function in HIV-infected persons with asymptomatic cryptococcal antigenemia: a comparison of three prospective cohorts.

Montgomery MP, Nakasujja N, Morawski BM, Rajasingham R, Rhein J, Nalintya E, Williams DA, Huppler Hullsiek K, Kiragga A, Rolfes MA, Donahue Carlson R, Bahr NC, Birkenkamp KE, Manabe YC, Bohjanen PR, Kaplan JE, Kambugu A, Meya DB, Boulware DR,

BMC neurology.. 2017 June 1217 (1):110. Epub 06/12/2017.

Monocyte Phenotype and IFN-?-Inducible Cytokine Responses Are Associated with Cryptococcal Immune Reconstitution Inflammatory Syndrome.

Meya DB, Okurut S, Zziwa G, Cose S, Bohjanen PR, Mayanja-Kizza H, Joloba M, Boulware DR, Yukari Manabe C, Wahl S, Janoff EN

Journal of fungi.. 2017 June 23 (2)Epub 06/02/2017.

Different Lymphocyte Populations Direct Dichotomous Eosinophil or Neutrophil Responses to Pulmonary Cryptococcus Infection.

Wiesner DL, Smith KD, Kashem SW, Bohjanen PR, Nielsen K

The Journal of immunology : official journal of the American Association of Immunologists.. 2017 February 15198 (4):1627-1637. Epub 01/09/2017.

Post-transcriptional regulation of cytokine and growth factor signaling in cancer.

Vlasova-St Louis I, Bohjanen PR

Cytokine & growth factor reviews.. 2017 February 33 :83-93. Epub 12/02/2016.

Evolving Failures in the Delivery of Human Immunodeficiency Virus Care: Lessons From a Ugandan Meningitis Cohort 2006-2016.

Flynn AG, Meya DB, Hullsiek KH, Rhein J, Williams DA, Musubire A, Morawski BM, Taseera K, Sadiq A, Ndyatunga L, Roediger M, Rajasingham R, Bohjanen PR, Muzoora C, Boulware DR

Open forum infectious diseases.. 2017 4 (2):ofx077. Epub 04/19/2017.

A Systematic Review of Non-Traumatic Spinal Cord Injuries in Sub-Saharan Africa and a Proposed Diagnostic Algorithm for Resource-Limited Settings.

Musubire AK, Meya DB, Bohjanen PR, Katabira ET, Barasukana P, Boulware DR, Meyer AC

Frontiers in neurology. 2017 8 :618. Epub 12/08/2017.

Mechanisms of Accelerated Liver Fibrosis Progression during HIV Infection.

Debes JD, Bohjanen PR, Boonstra A

Journal of clinical and translational hepatology.. 2016 December 284 (4):328-335. Epub 11/21/2016.

Fatty Liver in Hispanics with HIV.

Debes JD, Marianelli LG, Frassone N, Ballari E, Castrillon ME, Zhang L, Bohjanen PR, Boulware DR

AIDS research and human retroviruses.. 2016 June 32 (6):515-6. Epub 04/08/2016.

Seroprevalence of histoplasmosis in Kampala, Uganda.

Bahr NC, Sarosi GA, Meya DB, Bohjanen PR, Richer SM, Swartzentruber S, Halupnick R, Jarrett D, Wheat LJ, Boulware DR

Medical mycology.. 2016 March 54 (3):295-300. Epub 11/02/2015.

Erratum for Rattenbacher et al., Analysis of CUGBP1 Targets Identifies GU-Repeat Sequences That Mediate Rapid mRNA Decay.

Rattenbacher B, Beisang D, Wiesner DL, Jeschke JC, von Hohenberg M, Vlasova-St Louis IA, Bohjanen PR

Molecular and cellular biology.. 2016 February 1536 (4):660. Epub 02/01/2016.

Feedback Regulation of Kinase Signaling Pathways by AREs and GREs.

Vlasova-St Louis I, Bohjanen PR

Cells.. 2016 January 255 (1)Epub 01/25/2016.

Regulatory T Cell Induction and Retention in the Lungs Drives Suppression of Detrimental Type 2 Th Cells During Pulmonary Cryptococcal Infection.

Wiesner DL, Smith KD, Kotov DI, Nielsen JN, Bohjanen PR, Nielsen K

The Journal of immunology : official journal of the American Association of Immunologists.. 2016 January 1196 (1):365-74. Epub 11/20/2015.

Increased Hepatitis E Virus Seroprevalence Correlates with Lower CD4+ Cell Counts in HIV-Infected Persons in Argentina.

Debes JD, Martínez Wassaf M, Pisano MB, Isa MB, Lotto M, Marianelli LG, Frassone N, Ballari E, Bohjanen PR, Hansen BE, Ré V

PloS one.. 2016 11 (7):e0160082. Epub 07/28/2016.

Cerebrospinal Fluid Culture Positivity and Clinical Outcomes After Amphotericin-Based Induction Therapy for Cryptococcal Meningitis.

Rolfes MA, Rhein J, Schutz C, Taseera K, Nabeta HW, Huppler Hullsiek K, Akampuira A, Rajasingham R, Musubire A, Williams DA, Thienemann F, Bohjanen PR, Muzoora C, Meintjes G, Meya DB, Boulware DR

Open forum infectious diseases.. 2015 December 2 (4):ofv157. Epub 12/28/2015.

Altered CELF1 binding to target transcripts in malignant T cells.

Bohjanen PR, Moua ML, Guo L, Taye A, Vlasova-St Louis IA

RNA.. 2015 October 21 (10):1757-69. Epub 08/06/2015.

Gastrointestinal cryptococcoma - Immune reconstitution inflammatory syndrome or cryptococcal relapse in a patient with AIDS?

Musubire AK, Meya DB, Lukande R, Kambugu A, Bohjanen PR, Boulware DR

Medical mycology case reports.. 2015 June 8 :40-3. Epub 03/26/2015.

Cellular immune activation in cerebrospinal fluid from ugandans with cryptococcal meningitis and immune reconstitution inflammatory syndrome.

Meya DB, Okurut S, Zziwa G, Rolfes MA, Kelsey M, Cose S, Joloba M, Naluyima P, Palmer BE, Kambugu A, Mayanja-Kizza H, Bohjanen PR, Eller MA, Wahl SM, Boulware DR, Manabe YC, Janoff EN

The Journal of infectious diseases.. 2015 May 15211 (10):1597-606. Epub 12/09/2014.

Chitin recognition via chitotriosidase promotes pathologic type-2 helper T cell responses to cryptococcal infection.

Wiesner DL, Specht CA, Lee CK, Smith KD, Mukaremera L, Lee ST, Lee CG, Elias JA, Nielsen JN, Boulware DR, Bohjanen PR, Jenkins MK, Levitz SM, Nielsen K

PLoS pathogens.. 2015 March 11 (3):e1004701. Epub 03/12/2015.

Human papillomavirus vaccine acceptance among young men in Bangalore, India.

Belani HK, Sekar P, Guhaniyogi R, Abraham A, Bohjanen PR, Bohjanen K

International journal of dermatology.. 2014 November 53 (11):e486-91. Epub 06/25/2014.

Alternative polyadenylation regulates CELF1/CUGBP1 target transcripts following T cell activation.

Beisang D, Reilly C, Bohjanen PR

Gene.. 2014 October 15550 (1):93-100. Epub 08/11/2014.

Timing of antiretroviral therapy after diagnosis of cryptococcal meningitis.

Boulware DR, Meya DB, Muzoora C, Rolfes MA, Huppler Hullsiek K, Musubire A, Taseera K, Nabeta HW, Schutz C, Williams DA, Rajasingham R, Rhein J, Thienemann F, Lo MW, Nielsen K, Bergemann TL, Kambugu A, Manabe YC, Janoff EN, Bohjanen PR, Meintjes G,

The New England journal of medicine.. 2014 June 26370 (26):2487-98. Epub 1900 01 01.

Post-transcriptional regulation of cytokine signaling by AU-rich and GU-rich elements.

Vlasova-St Louis I, Bohjanen PR

Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research.. 2014 April 34 (4):233-41. Epub 1900 01 01.

AIDS-related mycoses: the way forward.

Brown GD, Meintjes G, Kolls JK, Gray C, Horsnell W, , Achan B, Alber G, Aloisi M, Armstrong-James D, Beale M, Bicanic T, Black J, Bohjanen P, Botes A, Boulware DR, Brown G, Bunjun R, Carr W, Casadevall A, Chang C, Chivero E, Corcoran C, Cross A, Dawood H, Day J, De Bernardis F, De Jager V, De Repentigny L, Denning D, Eschke M, Finkelman M, Govender N, Gow N, Graham L, Gryschek R, Hammond-Aryee K, Harrison T, Heard N, Hill M, Hoving JC, Janoff E, Jarvis J, Kayuni S, King K, Kolls J, Kullberg BJ, Lalloo DG, Letang E, Levitz S, Limper A, Longley N, Machiridza TR, Mahabeer Y, Martinsons N, Meiring S, Meya D, Miller R, Molloy S, Morris L, Mukaremera L, Musubire AK, Muzoora C, Nair A, Nakiwala Kimbowa J, Netea M, Nielsen K, O'hern J, Okurut S, Parker A, Patterson T, Pennap G, Perfect J, Prinsloo C, Rhein J, Rolfes MA, Samuel C, Schutz C, Scriven J, Sebolai OM, Sojane K, Sriruttan C, Stead D, Steyn A, Thawer NK, Thienemann F, Von Hohenberg M, Vreulink JM, Wessels J, Wood K, Yang YL

Trends in microbiology.. 2014 March 22 (3):107-9. Epub 1900 01 01.

CELFish ways to modulate mRNA decay.

Vlasova-St Louis I, Dickson AM, Bohjanen PR, Wilusz CJ

Biochimica et biophysica acta.. 2013 1829 (6-7):695-707. Epub 01/15/2013.

Challenges in diagnosis and management of Cryptococcal immune reconstitution inflammatory syndrome (IRIS) in resource limited settings.

Musubire AK, Meya BD, Mayanja-Kizza H, Lukande R, Wiesner LD, Bohjanen P, R Boulware RD

African health sciences.. 2012 June 12 (2):226-30. Epub 1900 01 01.

Regulation of CUG-binding protein 1 (CUGBP1) binding to target transcripts upon T cell activation.

Beisang D, Rattenbacher B, Vlasova-St Louis IA, Bohjanen PR

The Journal of biological chemistry.. 2012 January 6287 (2):950-60. Epub 11/23/2011.

Evaluating posttranscriptional regulation of cytokine genes.

Rattenbacher B, Bohjanen PR

Methods in molecular biology.. 2012 820 :71-89. Epub 1900 01 01.

Perspectives on the ARE as it turns 25 years old.

Beisang D, Bohjanen PR

Wiley interdisciplinary reviews. RNA.. 2012 3 (5):719-31. Epub 06/25/2012.

Cryptococcal genotype influences immunologic response and human clinical outcome after meningitis.

Wiesner DL, Moskalenko O, Corcoran JM, McDonald T, Rolfes MA, Meya DB, Kajumbula H, Kambugu A, Bohjanen PR, Knight JF, Boulware DR, Nielsen K

mBio.. 2012 3 (5)Epub 09/25/2012.

Long term 5-year survival of persons with cryptococcal meningitis or asymptomatic subclinical antigenemia in Uganda.

Butler EK, Boulware DR, Bohjanen PR, Meya DB

PloS one.. 2012 7 (12):e51291. Epub 12/10/2012.

Coordinate regulation of mRNA decay networks by GU-rich elements and CELF1.

Vlasova-St Louis I, Bohjanen PR

Current opinion in genetics & development.. 2011 August 21 (4):444-51. Epub 04/13/2011.

Higher levels of CRP, D-dimer, IL-6, and hyaluronic acid before initiation of antiretroviral therapy (ART) are associated with increased risk of AIDS or death.

Boulware DR, Hullsiek KH, Puronen CE, Rupert A, Baker JV, French MA, Bohjanen PR, Novak RM, Neaton JD, Sereti I,

The Journal of infectious diseases.. 2011 June 1203 (11):1637-46. Epub 1900 01 01.

Global assessment of GU-rich regulatory content and function in the human transcriptome.

Halees AS, Hitti E, Al-Saif M, Mahmoud L, Vlasova-St Louis IA, Beisang DJ, Bohjanen PR, Khabar K

RNA biology.. 2011 8 (4):681-91. Epub 07/01/2011.

Clinical features and serum biomarkers in HIV immune reconstitution inflammatory syndrome after cryptococcal meningitis: a prospective cohort study.

Boulware DR, Meya DB, Bergemann TL, Wiesner DL, Rhein J, Musubire A, Lee SJ, Kambugu A, Janoff EN, Bohjanen PR

PLoS medicine.. 2010 December 217 (12):e1000384. Epub 12/21/2010.

Antiretroviral therapy down-regulates innate antiviral response genes in patients with AIDS in sub-saharan Africa.

Boulware DR, Meya DB, Bergemann TL, Williams D, Vlasova-St Louis IA, Rhein J, Staddon J, Kambugu A, Janoff EN, Bohjanen PR

Journal of acquired immune deficiency syndromes : JAIDS.. 2010 December 55 (4):428-38. Epub 1900 01 01.

Cryptococcal immune reconstitution inflammatory syndrome in HIV-1-infected individuals: proposed clinical case definitions.

Haddow LJ, Colebunders R, Meintjes G, Lawn SD, Elliott JH, Manabe YC, Bohjanen PR, Sungkanuparph S, Easterbrook PJ, French MA, Boulware DR,

The Lancet. Infectious diseases.. 2010 November 10 (11):791-802. Epub 1900 01 01.

Paucity of initial cerebrospinal fluid inflammation in cryptococcal meningitis is associated with subsequent immune reconstitution inflammatory syndrome.

Boulware DR, Bonham SC, Meya DB, Wiesner DL, Park GS, Kambugu A, Janoff EN, Bohjanen PR

The Journal of infectious diseases.. 2010 September 15202 (6):962-70. Epub 1900 01 01.

Cost-effectiveness of serum cryptococcal antigen screening to prevent deaths among HIV-infected persons with a CD4+ cell count < or = 100 cells/microL who start HIV therapy in resource-limited settings.

Meya DB, Manabe YC, Castelnuovo B, Cook BA, Elbireer AM, Kambugu A, Kamya MR, Bohjanen PR, Boulware DR

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.. 2010 August 1551 (4):448-55. Epub 1900 01 01.

Analysis of CUGBP1 targets identifies GU-repeat sequences that mediate rapid mRNA decay.

Rattenbacher B, Beisang D, Wiesner DL, Jeschke JC, von Hohenberg M, St Louis-Vlasova IA, Bohjanen PR

Molecular and cellular biology.. 2010 August 30 (16):3970-80. Epub 06/14/2010.

Gene regulation and chromatin remodeling by IL-12 and type I IFN in programming for CD8 T cell effector function and memory.

Agarwal P, Raghavan A, Nandiwada SL, Curtsinger JM, Bohjanen PR, Mueller DL, Mescher MF

The Journal of immunology : official journal of the American Association of Immunologists.. 2009 August 1183 (3):1695-704. Epub 07/10/2009.

Tristetraprolin mediates interferon-gamma mRNA decay.

Ogilvie RL, Sternjohn JR, Rattenbacher B, Vlasova IA, Williams DA, Hau HH, Blackshear PJ, Bohjanen PR

The Journal of biological chemistry.. 2009 April 24284 (17):11216-23. Epub 03/03/2009.

Immunopathogenesis of immune reconstitution disease in HIV patients responding to antiretroviral therapy.

Kestens L, Seddiki N, Bohjanen PR

Current opinion in HIV and AIDS.. 2008 July 3 (4):419-24. Epub 1900 01 01.

Outcomes of cryptococcal meningitis in Uganda before and after the availability of highly active antiretroviral therapy.

Kambugu A, Meya DB, Rhein J, O'Brien M, Janoff EN, Ronald AR, Kamya MR, Mayanja-Kizza H, Sande MA, Bohjanen PR, Boulware DR

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.. 2008 June 146 (11):1694-701. Epub 1900 01 01.

Conserved GU-rich elements mediate mRNA decay by binding to CUG-binding protein 1.

Vlasova IA, Tahoe NM, Fan D, Larsson O, Rattenbacher B, Sternjohn JR, Vasdewani J, Karypis G, Reilly CS, Bitterman PB, Bohjanen PR

Molecular cell.. 2008 February 129 (2):263-70. Epub 1900 01 01.

Posttranscriptional regulation of gene networks by GU-rich elements and CELF proteins.

Vlasova IA, Bohjanen PR

RNA biology.. 2008 5 (4):201-7. Epub 10/23/2008.

Biomarkers of HIV Immune Reconstitution Inflammatory Syndrome.

Bonham S, Meya DB, Bohjanen PR, Boulware DR

Biomarkers in medicine.. 2008 2 (4):349-361. Epub 1900 01 01.

Three functional variants of IFN regulatory factor 5 (IRF5) define risk and protective haplotypes for human lupus.

Graham RR, Kyogoku C, Sigurdsson S, Vlasova IA, Davies LR, Baechler EC, Plenge RM, Koeuth T, Ortmann WA, Hom G, Bauer JW, Gillett C, Burtt N, Cunninghame Graham DS, Onofrio R, Petri M, Gunnarsson I, Svenungsson E, Rönnblom L, Nordmark G, Gregersen PK, Moser K, Gaffney PM, Criswell LA, Vyse TJ, Syvänen AC, Bohjanen PR, Daly MJ, Behrens TW, Altshuler D

Proceedings of the National Academy of Sciences of the United States of America.. 2007 April 17104 (16):6758-63. Epub 04/05/2007.

Tristetraprolin recruits functional mRNA decay complexes to ARE sequences.

Hau HH, Walsh RJ, Ogilvie RL, Williams DA, Reilly CS, Bohjanen PR

Journal of cellular biochemistry.. 2007 April 15100 (6):1477-92. Epub 1900 01 01.

A case for treating high hepatitis B DNA levels before starting HIV therapy.

Baker JV, Boulware DR, Bohjanen PR

AIDS.. 2006 November 2820 (18):2402-3. Epub 1900 01 01.

Global assessment of cross-hybridization for oligonucleotide arrays.

Reilly C, Raghavan A, Bohjanen P

Journal of biomolecular techniques : JBT.. 2006 April 17 (2):163-72. Epub 1900 01 01.

Reovirus induces and benefits from an integrated cellular stress response.

Smith JA, Schmechel SC, Raghavan A, Abelson M, Reilly C, Katze MG, Kaufman RJ, Bohjanen PR, Schiff LA

Journal of virology.. 2006 February 80 (4):2019-33. Epub 1900 01 01.

Coordinate stabilization of growth-regulatory transcripts in T cell malignancies.

Vlasova IA, McNabb J, Raghavan A, Reilly C, Williams DA, Bohjanen KA, Bohjanen PR

Genomics.. 2005 August 86 (2):159-71. Epub 1900 01 01.

Tristetraprolin down-regulates IL-2 gene expression through AU-rich element-mediated mRNA decay.

Ogilvie RL, Abelson M, Hau HH, Vlasova I, Blackshear PJ, Bohjanen PR

The Journal of immunology : official journal of the American Association of Immunologists.. 2005 January 15174 (2):953-61. Epub 1900 01 01.

Patterns of coordinate down-regulation of ARE-containing transcripts following immune cell activation.

Raghavan A, Dhalla M, Bakheet T, Ogilvie RL, Vlasova IA, Khabar KS, Williams BR, Bohjanen PR

Genomics.. 2004 December 84 (6):1002-13. Epub 1900 01 01.

Microarray-based analyses of mRNA decay in the regulation of mammalian gene expression.

Raghavan A, Bohjanen PR

Briefings in functional genomics & proteomics.. 2004 August 3 (2):112-24. Epub 1900 01 01.

Genome-wide analysis of mRNA decay in resting and activated primary human T lymphocytes.

Raghavan A, Ogilvie RL, Reilly C, Abelson ML, Raghavan S, Vasdewani J, Krathwohl M, Bohjanen PR

Nucleic acids research.. 2002 December 1530 (24):5529-38. Epub 1900 01 01.

Steady-state pharmacokinetics of lamivudine in human immunodeficiency virus-infected patients with end-stage renal disease receiving chronic dialysis.

Bohjanen PR, Johnson MD, Szczech LA, Wray DW, Petros WP, Miller CR, Hicks CB

Antimicrobial agents and chemotherapy.. 2002 August 46 (8):2387-92. Epub 1900 01 01.

HuA and tristetraprolin are induced following T cell activation and display distinct but overlapping RNA binding specificities.

Raghavan A, Robison RL, McNabb J, Miller CR, Williams DA, Bohjanen PR

The Journal of biological chemistry.. 2001 December 21276 (51):47958-65. Epub 10/15/2001.

Human immunodeficiency virus type I as a target for gene therapy.

Gottfredsson M, Bohjanen PR

Frontiers in bioscience : a journal and virtual library.. 1997 December 152 :d619-34. Epub 12/15/1997.

TAR RNA decoys inhibit tat-activated HIV-1 transcription after preinitiation complex formation.

Bohjanen PR, Liu Y, Garcia-Blanco MA

Nucleic acids research.. 1997 November 1525 (22):4481-6. Epub 1900 01 01.

A small circular TAR RNA decoy specifically inhibits Tat-activated HIV-1 transcription.

Bohjanen PR, Colvin RA, Puttaraju M, Been MD, Garcia-Blanco MA

Nucleic acids research.. 1996 October 124 (19):3733-8. Epub 1900 01 01.

DNA fragments of altered electrophoretic mobility in leukemia samples can arise from double-strand DNA breaks at nuclease hypersensitive sites of active genes.

Miesfeldt S, Kim S, Hanson CA, Bohjanen PR, Leiden JM, Crist WM, Carroll AJ, Thompson CB

Cancer genetics and cytogenetics.. 1993 July 168 (1):34-41. Epub 1900 01 01.

AU RNA-binding factors differ in their binding specificities and affinities.

Bohjanen PR, Petryniak B, June CH, Thompson CB, Lindsten T

The Journal of biological chemistry.. 1992 March 25267 (9):6302-9. Epub 1900 01 01.

cis-acting sequences required for inducible interleukin-2 enhancer function bind a novel Ets-related protein, Elf-1.

Thompson CB, Wang CY, Ho IC, Bohjanen PR, Petryniak B, June CH, Miesfeldt S, Zhang L, Nabel GJ, Karpinski B

Molecular and cellular biology.. 1992 March 12 (3):1043-53. Epub 1900 01 01.

An inducible cytoplasmic factor (AU-B) binds selectively to AUUUA multimers in the 3' untranslated region of lymphokine mRNA.

Bohjanen PR, Petryniak B, June CH, Thompson CB, Lindsten T

Molecular and cellular biology.. 1991 June 11 (6):3288-95. Epub 1900 01 01.

Differential regulation of interleukin 4 and interleukin 5 gene expression: a comparison of T-cell gene induction by anti-CD3 antibody or by exogenous lymphokines.

Bohjanen PR, Okajima M, Hodes RJ

Proceedings of the National Academy of Sciences of the United States of America.. 1990 July 87 (14):5283-7. Epub 1900 01 01.