Welcome to the Department of Pharmacology & Physiology
A Message from the Chair:
The Department of Pharmacology and Physiology consists of faculty, fellows and students who are dedicated to cutting-edge scientific research, in order to work towards a better understanding of how the human body functions and to alleviate human diseases. The faculty is composed of distinguished scientists who are international leaders in the fields of cell signaling, G-proteins and ion channels, mitochondria and mechanisms of cell death, cardiovascular diseases and vascular biology, neurodegeneration and drugs of abuse, and integrative neurosciences. The department promotes a strong training program for both graduate students and post-doctoral fellows, and many of our graduates have gone on to become leaders in academia, industry and government. The University of Rochester is now in the process of implementing a new strategic plan, which emphasizes a number of research fields, including neuromedicine and cardiovascular biology, that fit well with the Department’s research interests. The Department is enthusiastic about being a part of this plan and the anticipated growth in the University’s research enterprise, as we aim to be one of the finest medical centers in the world.
Robert T. Dirksen, Ph.D.
Lewis Pratt Ross Professor of Pharmacology and Physiology and Chair
August 26, 2015: New patent issued for Professor Hicking
The patent titled “Chimeric Fibronectin Matrix Mimetics and Uses Thereof” (US 9,072,706) has recently been assigned to the UR with inventors Denise Hocking, Ph.D. (Pharmacology and Physiology, BME, RCBU) and Daniel Roy, Ph.D. (BME PhD 2012 alumnus). The patent relates to a series of recombinant fibronectin peptide mimetics developed to promote wound repair. The technology falls under a new and exciting class of therapies known as wound biologics. The primary commercial application for this technology is to promote healing of hard-to-heal or chronic wounds, including diabetic, venous, and pressure ulcers, which impose a significant health care burden worldwide. Encouraging results from recent studies indicate that topical application of these fibronectin peptide mimetics to full-thickness excisional wounds in diabetic mice accelerates wound closure and promotes granulation tissue deposition, remodeling, and re-vascularization. Denise Hocking is an Associate Professor of Pharmacology and Physiology and of Biomedical Engineering. Daniel Roy is currently a post-doctoral fellow at the US Army Institute of Surgical Research in San Antonio, TX.
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Department of Pharmacology and Physiology
University of Rochester Medical Center
601 Elmwood Avenue, Box 711
Rochester, NY 14642
Phone, (585) 275-1679
Fax, (585) 273-2652