CRLUN22012 / NRG-CC009 / Milano
Basic Study Information
Purpose:
This phase III trial compares the effect of stereotactic radiosurgery to standard
of care memantine and whole brain radiation therapy that avoids the hippocampus (the
memory zone of the brain) for the treatment of small cell lung cancer that has spread
to the brain. Stereotactic radiosurgery is a specialized radiation therapy that delivers
a single, high dose of radiation directly to the tumor and may cause less damage to
normal tissue. Whole brain radiation therapy delivers a low dose of radiation to the
entire brain including the normal brain tissue. Hippocampal avoidance during whole-brain
radiation therapy (HA-WBRT) decreases the amount of radiation that is delivered to
the hippocampus which is a brain structure that is important for memory. The drug,
memantine, is also often given with whole brain radiotherapy because it may decrease
the risk of side effects related to thinking and memory. Stereotactic radiosurgery
may decrease side effects related to memory and thinking compared to standard of care
HA-WBRT plus memantine.
Location: University of Rochester
Lead Researcher (Principal Investigator)
Lead Researcher:
Michael Milano
Study Contact Information
Study Contact: Clinical Trials Office
Study Location: Wilmot Cancer Institute, University of Rochester Medical Center
Study Email: WCICTOResearch@urmc.rochester.edu
Additional Study Details
Trial Not Found
The study you are looking for is not active at this time.
Return to Search