URMC / Biochemistry & Biophysics / Research / Recent Publications Recent Publications Lucas BALavi EShiue LCho HKatzman SMiyoshi KSiomi MCCarmel LAres MMaquat LE (2018 Jan 16). Evidence for convergent evolution of SINE-directed Staufen-mediated mRNA decay. Proceedings of the National Academy of Sciences of the United States of America. Thompson JLZhao YStathopulos PBGrossfield AShuttleworth TJ (2018 Jan 11). Phosphorylation-mediated structural changes within the SOAR domain of STIM1 enable specific activation of distinct Orai channels. The Journal of biological chemistry. Hardcastle TNovosjolova IKotikam VCheruiyot SKMutisya DKennedy SDEgli MKelley MLSmith AVBRozners E (2018 Jan 03). A Single Amide Linkage in the Passenger Strand Suppresses Its Activity and Enhances Guide Strand Targeting of siRNAs. ACS chemical biology. Payea MJSloma MFKon YYoung DLGuy MPZhang XDe Zoysa TFields SMathews DHPhizicky EM (2017 Dec 19). Widespread temperature sensitivity and tRNA decay due to mutations in a yeast tRNA. RNA (New York, N.Y.). Rambout XDequiedt FMaquat LE (2017 Dec 18). Beyond Transcription: Roles of Transcription Factors in Pre-mRNA Splicing. Chemical reviews. Lai CWErmolenko DN (2017 Dec 13). Ensemble and single-molecule FRET studies of protein synthesis. Methods (San Diego, Calif.). Kong WZhu J (2017 Dec 11). Zika virus: The transboundary pathogen from mosquito and updates. Microbial pathogenesis. Spasic AAssmann SMBevilacqua PCMathews DH (2017 Nov 21). Modeling RNA secondary structure folding ensembles using SHAPE mapping data. Nucleic acids research. Gatchalian JWang XIkebe JCox KLTencer AHZhang YBurge NLDi LGibson MDMusselman CAPoirier MGKono HHayes JJKutateladze TG (2017 Nov 14). Accessibility of the histone H3 tail in the nucleosome for binding of paired readers. Nature communications. Kielkopf CL (2017 Nov 09). Insights from structures of cancer-relevant pre-mRNA splicing factors. Current opinion in genetics & development. Wakabayashi HTucker CBethlendy GKravets AWelle SLBulger MHayes JJRustchenko E (2017 Nov 07). Correction to: NuA4 histone acetyltransferase activity is required for H4 acetylation on a dosage-compensated monosomic chromosome that confers resistance to fungal toxins. Epigenetics & chromatin. Popp MWMaquat LE (2017 Nov 07). Nonsense-mediated mRNA Decay and Cancer. Current opinion in genetics & development. Sloma MFMathews DH (2017 Nov 06). Base pair probability estimates improve the prediction accuracy of RNA non-canonical base pairs. PLoS computational biology. Walling LRButler JS (2017 Nov 06). Homologous VapC toxins inhibit translation and cell growth by sequence specific cleavage of tRNA(fMet). Journal of bacteriology. Ge JKarijolich JZhai YZheng JYu YT (2017 Oct 31). 5-Fluorouracil Treatment Alters the Efficiency of Translational Recoding. Genes. Wakabayashi HTucker CBethlendy GKravets AWelle SLBulger MHayes JRustchenko E (2017 Oct 23). NuA4 histone acetyltransferase activity is required for H4 acetylation on a dosage-compensated monosomic chromosome that confers resistance to fungal toxins. Epigenetics & chromatin. Jiang MLi HZhang YYang YLu RLiu KLin SLan XWang HWu HZhu JZhou ZXu JLee DKZhang LLee YCYuan JAbrams JAWang TCSepulveda ARWu QChen HSun XShe JChen XQue J (2017 Oct 11). Transitional basal cells at the squamous-columnar junction generate Barrett's oesophagus. Nature. Tencer AHCox KLDi LBridgers JBLyu JWang XSims JKWeaver TMAllen HFZhang YGatchalian JDarcy MAGibson MDIkebe JLi WWade PAHayes JJStrahl BDKono HPoirier MGMusselman CAKutateladze TG (2017 Oct 10). Covalent Modifications of Histone H3K9 Promote Binding of CHD3. Cell reports. Murphy KJCutter ARFang HPostnikov YVBustin MHayes JJ (2017 Sep 29). HMGN1 and 2 remodel core and linker histone tail domains within chromatin. Nucleic acids research. Tan ZFu YSharma GMathews DH (2017 Sep 28). TurboFold II: RNA structural alignment and secondary structure prediction informed by multiple homologs. Nucleic acids research. Glasser EAgrawal AAJenkins JLKielkopf CL (2017 Sep 01). Cancer-Associated Mutations Mapped on High-Resolution Structures of the U2AF2 RNA Recognition Motifs. Biochemistry. Smith LGZhao JMathews DHTurner DH (2017 Sep). Physics-based all-atom modeling of RNA energetics and structure. Wiley interdisciplinary reviews. RNA. Novosjolova IKennedy SDRozners E (2017 Aug 31). 2-Methoxypyridine as Thymidine Mimic in Watson-Crick Base Pairs of DNA and PNA: Synthesis, Thermal Stability and NMR Structural Studies. Chembiochem : a European journal of chemical biology. Hayashi TJean MHuang HSimpson SSantoso NGZhu J (2017 Aug 22). Screening of an FDA-approved compound library identifies levosimendan as a novel anti-HIV-1 agent that inhibits viral transcription. Antiviral research. Mutisya DHardcastle TCheruiyot SKPallan PSKennedy SDEgli MKelley MLSmith AVBRozners E (2017 Aug 21). Amide linkages mimic phosphates in RNA interactions with proteins and are well tolerated in the guide strand of short interfering RNAs. Nucleic acids research. Poole ARVicino IAdachi HYu YTHebert MD (2017 Aug 14). Regulatory RNPs: a novel class of ribonucleoproteins that potentially contribute to ribosome heterogeneity. Biology open. Tan ZSharma GMathews DH (2017 Jul 20). Modeling RNA Secondary Structure with Sequence Comparison and Experimental Mapping Data. Biophysical journal. Elbarbary RAMiyoshi KHedaya OMyers JRMaquat LE (2017 Jul 15). UPF1 helicase promotes TSN-mediated miRNA decay. Genes & development. Kauffmann ADKennedy SDZhao JTurner DH (2017 Jul 12). Nuclear Magnetic Resonance Structure of an 8 × 8 Nucleotide RNA Internal Loop Flanked on Each Side by Three Watson-Crick Pairs and Comparison to Three-Dimensional Predictions. Biochemistry. Huang YSDelgadillo LFCyr KHKingsley PDAn XMcGrath KEMohandas NConboy JGWaugh REWan JPalis J (2017 Jul 12). Circulating primitive erythroblasts establish a functional, protein 4.1R-dependent cytoskeletal network prior to enucleating. Scientific reports. Romo TDLewis AKBraun ARGrossfield ASachs JN (2017 Jul 05). Minimal nucleation state of alpha-Synuclein is stabilized by dynamic threonine-water networks. ACS chemical neuroscience. Nadtochiy SMWang YTZhang JNehrke KSchafer XWelle KGhaemmaghami SMunger JBrookes PS (2017 Jul 03). Potential mechanisms linking SIRT activity and hypoxic 2-hydroxyglutarate generation: no role for direct enzyme (de)acetylation. The Biochemical journal. Ward MDatta AWise MMathews DH (2017 Jun 06). Advanced multi-loop algorithms for RNA secondary structure prediction reveal that the simplest model is best. Nucleic acids research. Elbarbary RAMaquat LE (2017 Jun 06). Distinct mechanisms obviate the potentially toxic effects of inverted-repeat Alu elements on cellular RNA metabolism. Nature structural & molecular biology. Bednar JGarcia-Saez IBoopathi RCutter ARPapai GReymer ASyed SHLone INTonchev OCrucifix CMenoni HPapin CSkoufias DAKurumizaka HLavery RHamiche AHayes JJSchultz PAngelov DPetosa CDimitrov S (2017 Jun 01). Structure and Dynamics of a 197 bp Nucleosome in Complex with Linker Histone H1. Molecular cell. Elbarbary RAMiyoshi KMyers JRDu PAshton JMTian BMaquat LE (2017 May 26). Tudor-SN-mediated endonucleolytic decay of human cell microRNAs promotes G1/S phase transition. Science (New York, N.Y.). Polevoda BJoseph RFriedman AEBennett RPGreiner RDe Zoysa TStewart RASmith HC (2017 May 26). DNA mutagenic activity and capacity for HIV-1 restriction of the cytidine deaminase APOBEC3G depend on whether DNA or RNA binds to tyrosine 315. The Journal of biological chemistry. Hilimire TAChamberlain JMAnokhina VBennett RPSwart OMyers JRAshton JMStewart RAFeatherston ALGates KHelms EDSmith HCDewhurst SMiller BL (2017 May 05). HIV-1 Frameshift RNA-Targeted Triazoles Inhibit Propagation of Replication-Competent and Multi-Drug-Resistant HIV in Human Cells. ACS chemical biology. Bednar JGarcia-Saez IBoopathi RCutter ARPapai GReymer ASyed SHLone INTonchev OCrucifix CMenoni HPapin CSkoufias DAKurumizaka HLavery RHamiche AHayes JJSchultz PAngelov DPetosa CDimitrov S (2017 May 04). Structure and Dynamics of a 197 bp Nucleosome in Complex with Linker Histone H1. Molecular cell. East-Seletsky AO'Connell MRBurstein DKnott GJDoudna JA (2017 May 04). RNA Targeting by Functionally Orthogonal Type VI-A CRISPR-Cas Enzymes. Molecular cell. Wedekind JEDutta DBelashov IAJenkins JL (2017 Apr 28). Metalloriboswitches: RNA-Based Inorganic Ion Sensors that Regulate Genes. The Journal of biological chemistry. Gamache ERDoh JHRitz JLaederach ABellaousov SMathews DHCurcio MJ (2017 Apr 26). Structure-Function Model for Kissing Loop Interactions That Initiate Dimerization of Ty1 RNA. Viruses. Sun YHXie LHZhuo XChen QGhoneim DZhang BJagne JYang CLi XZ (2017 Apr 06). Domestic chickens activate a piRNA defense against avian leukosis virus. eLife. Jean MJPower DKong WHuang HSantoso NZhu J (2017 Apr 01). Identification of HIV-1 Tat-Associated Proteins Contributing to HIV-1 Transcription and Latency. Viruses. Vats KMarsh GHarding KZampetakis IWaugh REBenoit DS (2017 Apr). Nanoscale physicochemical properties of chain- and step-growth polymerized PEG hydrogels affect cell-material interactions. Journal of biomedical materials research. Part A. Cutter ARHayes JJ (2017 Apr). Linker histones: novel insights into structure-specific recognition of the nucleosome. Biochemistry and cell biology = Biochimie et biologie cellulaire. Jenkins JLKielkopf CL (2017 Mar 31). Splicing Factor Mutations in Myelodysplasias: Insights from Spliceosome Structures. Trends in genetics : TIG. Baker JESriram RMiller BL (2017 Mar 30). Recognition-mediated particle detection under microfluidic flow with waveguide-coupled 2D photonic crystals: towards integrated photonic virus detectors. Lab on a chip. Zuber JSun HZhang XMcFadyen IMathews DH (2017 Mar 15). A sensitivity analysis of RNA folding nearest neighbor parameters identifies a subset of free energy parameters with the greatest impact on RNA secondary structure prediction. Nucleic acids research. Liu KXie FGao AZhang RZhang LXiao ZHu QHuang WHuang QLin BZhu JWang HQue JLan X (2017 Mar 14). SOX2 regulates multiple malignant processes of breast cancer development through the SOX2/miR-181a-5p, miR-30e-5p/TUSC3 axis. Molecular cancer. Brule CEGrayhack EJ (2017 Mar 11). Synonymous Codons: Choose Wisely for Expression. Trends in genetics : TIG. Murphy PSWang JBhagwat SPMunger JCJanssen WJWright TWElliott MR (2017 Mar). CD73 regulates anti-inflammatory signaling between apoptotic cells and endotoxin-conditioned tissue macrophages. Cell death and differentiation. Yang FZhang LWakabayashi HMyers JJiang YCao YJimenez-Ortigosa CPerlin DSRustchenko E (2017 Feb 21). Tolerance to caspofungin in Candida albicans is associated with at least three distinctive mechanisms that govern expression of FKS genes and cell wall remodeling. Antimicrobial agents and chemotherapy. Aytenfisu AHSpasic AGrossfield AStern HAMathews DH (2017 Feb 14). Revised RNA Dihedral Parameters for the Amber Force Field Improve RNA Molecular Dynamics. Journal of chemical theory and computation. Clark KMJenkins JLFedoriw NDumont ME (2017 Feb). Human CaaX protease ZMPSTE24 expressed in yeast: Structure and inhibition by HIV protease inhibitors. Protein science : a publication of the Protein Society. Balliano AHao FNjeri CBalakrishnan LHayes JJ (2017 Jan 18). HMGB1 Stimulates Activity of Polymerase β on Nucleosome Substrates. Biochemistry. Patra BKon YYadav GSevold AWFrumkin JPVallabhajosyula RRHintze AØstman BSchossau JBhan AMarzolf BTamashiro JKKaur ABaliga NSGrayhack EJAdami CGalas DJRaval APhizicky EMRay A (2017 Jan 09). A genome wide dosage suppressor network reveals genomic robustness. Nucleic acids research. Hrabeta-Robinson EMarcus ECozen AEPhizicky EMLowe TM (2017). High-Throughput Small RNA Sequencing Enhanced by AlkB-Facilitated RNA de-Methylation (ARM-Seq). Methods in molecular biology (Clifton, N.J.). De Zoysa MDYu YT (2017). Posttranscriptional RNA Pseudouridylation. The Enzymes. Huang HLiu SJean MSimpson SHuang HMerkley MHayashi TKong WRodríguez-Sánchez IZhang XYosief HOMiao HQue JKobie JJBradner JSantoso NGZhang WZhu J (2017). A Novel Bromodomain Inhibitor Reverses HIV-1 Latency through Specific Binding with BRD4 to Promote Tat and P-TEFb Association. Frontiers in microbiology. Coudray NL Seyler SLasala RZhang ZClark KMDumont MERohou ABeckstein OStokes DL (2017 Jan). Structure of the SLC4 transporter Bor1p in an inward-facing conformation. Protein science : a publication of the Protein Society. Jean MJHayashi THuang HBrennan JSimpson SPurmal AGurova KKeefer MCKobie JJSantoso NGZhu J (2017). Curaxin CBL0100 Blocks HIV-1 Replication and Reactivation through Inhibition of Viral Transcriptional Elongation. Frontiers in microbiology. Han LMarcus ED'Silva SPhizicky EM (2016 Dec 21). S. cerevisiae Trm140 has two recognition modes for 3-methylcytidine modification of the anticodon loop of tRNA substrates. RNA (New York, N.Y.). Chatrikhi RWang WGupta ALoerch SMaucuer AKielkopf CL (2016 Dec 20). SF1 Phosphorylation Enhances Specific Binding to U2AF(65) and Reduces Binding to 3'-Splice-Site RNA. Biophysical journal. Komisarof JMcCall MNewman LBshara WMohler JLMorrison CLand H (2016 Dec 09). A four gene signature predictive of recurrent prostate cancer. Oncotarget. Ling CErmolenko DN (2016 Dec 06). Caught on Camera: Intermediates of Ribosome Recycling. Structure (London, England : 1993). Loerch SKielkopf CL (2016 Dec). Unmasking the U2AF homology motif family: a bona fide protein-protein interaction motif in disguise. RNA (New York, N.Y.). Suwunnakorn SWakabayashi HRustchenko E (2016 Dec). Chromosome 5 of Human Pathogen Candida albicans Carries Multiple Genes for Negative Control of Caspofungin and Anidulafungin Susceptibility. Antimicrobial agents and chemotherapy. Ikpeze TCSmith HCLee DJElfar JC (2016 Dec). Distal Radius Fracture Outcomes and Rehabilitation. Geriatric orthopaedic surgery & rehabilitation. Sloma MFMathews DH (2016 Dec). Exact calculation of loop formation probability identifies folding motifs in RNA secondary structures. RNA (New York, N.Y.). Mathews DHTurner DHWatson RM (2016 Dec 01). RNA Secondary Structure Prediction. Current protocols in nucleic acid chemistry. Pei SMinhajuddin MD'Alessandro ANemkov TStevens BMAdane BKhan NHagen FKYadav VKDe SAshton JMHansen KCGutman JAPollyea DACrooks PASmith CJordan CT (2016 Nov 25). Rational design of a parthenolide-based drug regimen that selectively eradicates acute myelogenous leukemia stem cells. The Journal of biological chemistry. Smith HC (2016 Nov 21). RNA binding to APOBEC deaminases; Not simply a substrate for C to U editing. RNA biology. Dutt SBinney RJHeuer HWLuong PAttygalle SBhatt PMarx GAElofson JTartaglia MCLitvan IMcGinnis SMDickerson BCKornak JWaltzman DVoltarelli LSchuff NRabinovici GDKramer JHJack CRMiller BLRosen HJBoxer AL (2016 Nov 08). Progression of brain atrophy in PSP and CBS over 6 months and 1 year. Neurology. Bennett RPStewart RAHogan PAPtak RGMankowski MKHartman TLBuckheit RWSnyder BASalter JDMorales GASmith HC (2016 Nov 4). An analog of camptothecin inactive against Topoisomerase I is broadly neutralizing of HIV-1 through inhibition of Vif-dependent APOBEC3G degradation. Antiviral research. Fang HWei SLee THHayes JJ (2016 Nov 02). Chromatin structure-dependent conformations of the H1 CTD. Nucleic acids research. Xu CIshikawa HIzumikawa KLi LHe HNobe YYamauchi YShahjee HMWu XHYu YTIsobe TTakahashi NMin J (2016 Nov 01). Structural insights into Gemin5-guided selection of pre-snRNAs for snRNP assembly. Genes & development. Pei SMinhajuddin MD'Alessandro ANemkov TStevens BMAdane BKhan NHagen FKYadav VKDe SAshton JMHansen KCGutman JAPollyea DACrooks PASmith CJordan CT (2016 Oct 14). Rational Design of a Parthenolide-based Drug Regimen That Selectively Eradicates Acute Myelogenous Leukemia Stem Cells. The Journal of biological chemistry. East-Seletsky AO'Connell MRKnight SCBurstein DCate JHTjian RDoudna JA (2016 Oct 13). Two distinct RNase activities of CRISPR-C2c2 enable guide-RNA processing and RNA detection. Nature. Smith BSchafer XLAmbeskovic ASpencer CMLand HMunger J (2016 Oct 11). Addiction to Coupling of the Warburg Effect with Glutamine Catabolism in Cancer Cells. Cell reports. Mishra LNPepenella SRogge RHansen JCHayes JJ (2016 Oct 06). Acetylation Mimics Within a Single Nucleosome Alter Local DNA Accessibility In Compacted Nucleosome Arrays. Scientific reports. Fei DLMotowski HChatrikhi RPrasad SYu JGao SKielkopf CLBradley RKVarmus H (2016 Oct). Wild-Type U2AF1 Antagonizes the Splicing Program Characteristic of U2AF1-Mutant Tumors and Is Required for Cell Survival. PLoS genetics. Walling LRButler JS (2016 Sep 26). Structural determinants for antitoxin identity and insulation of cross talk between homologous toxin-antitoxin systems. Journal of bacteriology. Sparks RPJenkins JLMiner GEWang YGuida WCSparks CEFratti RASparks JD (2016 Sep 22). Phosphatidylinositol (3,4,5)-trisphosphate binds to sortilin and competes with neurotensin: Implications for very low density lipoprotein binding. Biochemical and biophysical research communications. Sridharan RConnelly SMNaider FDumont ME (2016 Sep 19). Variable Dependence of Signaling Output on Agonist Occupancy of Ste2p, a G Protein Coupled Receptor in Yeast. The Journal of biological chemistry. Nadtochiy SMSchafer XFu DNehrke KMunger JBrookes PS (2016 Aug 10). Acidic pH is a Metabolic Switch for 2-Hydroxyglutarate Generation and Signaling. The Journal of biological chemistry. Sparks RPGuida WCSowden MPJenkins JLStarr MLFratti RASparks CESparks JD (2016 Aug 2). Sortilin facilitates VLDL-B100 secretion by insulin sensitive McArdle RH7777 cells. Biochemical and biophysical research communications. Gamble CEBrule CEDean KMFields SGrayhack EJ (2016 Jun 29). Adjacent Codons Act in Concert to Modulate Translation Efficiency in Yeast. Cell. Black PJMiller ASHayes JJ (2016 Jun 27). Radioresistance of GGG sequences to prompt strand break formation from direct-type radiation damage. Radiation and environmental biophysics. Gleghorn MLZhao JTurner DHMaquat LE (2016 Jun 10). Crystal structure of a poly(rA) staggered zipper at acidic pH: evidence that adenine N1 protonation mediates parallel double helix formation. Nucleic acids research. Wu GRadwan MKXiao MAdachi HFan JYu YT (2016 Jun 7). The TOR signaling pathway regulates starvation-induced pseudouridylation of yeast U2 snRNA. RNA (New York, N.Y.). Popp MWMaquat LE (2016 Jun 2). Leveraging Rules of Nonsense-Mediated mRNA Decay for Genome Engineering and Personalized Medicine. Cell. Svetina SKokot GKebe TŠŽekš BWaugh RE (2016 Jun). A novel strain energy relationship for red blood cell membrane skeleton based on spectrin stiffness and its application to micropipette deformation. Biomechanics and modeling in mechanobiology. Marsh GWaugh RE (2016 Jun). A simple approach for bioactive surface calibration using evanescent waves. Journal of microscopy. Coudray NLasala RZhang ZClark KMDumont MEStokes DL (2016 May 30). Deducing the Symmetry of Helical Assemblies: Applications to Membrane Proteins. Journal of structural biology. Salter JDBennett RPSmith HC (2016 May 30). The APOBEC Protein Family: United by Structure, Divergent in Function. Trends in biochemical sciences. Salsi EFarah EErmolenko DN (2016 May 22). EF-G Activation by Phosphate Analogs. Journal of molecular biology. Miralem TLerner-Marmarosh NGibbs PEJenkins JLHeimiller CMaines MD (2016 May 10). Interaction of human biliverdin reductase with Akt/protein kinase B and phosphatidylinositol-dependent kinase 1 regulates glycogen synthase kinase 3 activity: a novel mechanism of Akt activation. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. Xu SSchafer XMunger J (2016 May 1). Expression of Oncogenic Alleles Induces Multiple Blocks to Human Cytomegalovirus Infection. Journal of virology. Monaghan MWakabayashi HGriffiths AEFay PJ (2016 May). Stabilizing interactions between D666-S1787 and T657-Y1792 at the A2-A3 interface support factor VIIIa stability in the blood clotting pathway. Journal of thrombosis and haemostasis : JTH. Ling CErmolenko DN (2016 Apr 27). Structural insights into ribosome translocation. Wiley interdisciplinary reviews. RNA. Piekna-Przybylska DBambara RABalakrishnan L (2016 Apr 22). Acetylation regulates DNA repair mechanisms in human cells. Cell cycle (Georgetown, Tex.). Yue HFang HWei SHayes JJLee TH (2016 Apr 12). Single-Molecule Studies of the Linker Histone H1 Binding to DNA and the Nucleosome. Biochemistry. Shaheen RHan LFaqeih EEwida NAlobeid EPhizicky EMAlkuraya FS (2016 Apr 7). A homozygous truncating mutation in PUS3 expands the role of tRNA modification in normal cognition. Human genetics. Nelles DAFang MYO'Connell MRXu JLMarkmiller SJDoudna JAYeo GW (2016 Apr 07). Programmable RNA Tracking in Live Cells with CRISPR/Cas9. Cell. Maquat LE (2016 Apr). Eukaryotic antisense ahead of its time. 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Proceedings of the National Academy of Sciences of the United States of America. Hughes ADMarsh GWaugh REFoster DGKing MR (2015 Dec 22). Halloysite Nanotube Coatings Suppress Leukocyte Spreading. Langmuir : the ACS journal of surfaces and colloids. Zhu GKoszelak-Rosenblum MConnelly SMDumont MEMalkowski MG (2015 Dec 11). The Crystal Structure of an Integral Membrane Fatty Acid α-Hydroxylase. The Journal of biological chemistry. Quivey RGGrayhack EJFaustoferri RCHubbard CJBaldeck JDWolf ASMacGilvray MERosalen PLScott-Anne KSantiago BGopal SPayne JMarquis RE (2015 Dec). Functional profiling in Streptococcus mutans: construction and examination of a genomic collection of gene deletion mutants. Molecular oral microbiology. Balliano AJHayes JJ (2015 Dec). Base excision repair in chromatin: Insights from reconstituted systems. DNA repair. Goodwin CMXu SMunger J (2015 Dec). Stealing the Keys to the Kitchen: Viral Manipulation of the Host Cell Metabolic Network. Trends in microbiology. 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