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URMC / Biomedical Genetics / Events / GEN 506

 

Principles in Stem Cell Biology (GEN 506)

Available Spring 2020, Now Open to Undergraduate Students!

Team taught by UofR researchers actively working in the field of stem cell research, this course is an excellent opportunity for students to prepare for a future career in regenerative medicine, industry or graduate research. Or simply come to learn about one of the major revolutions in modern medicine!

This course is designed to cover: (1) basic principles in stem cell science, (2) the role of stem cell dysfunction in disease, (3) potential therapeutic applications of stem cells, (4) principles of embryonic stem cell and iPSC research and (5) managing the transition from the laboratory to the clinic. The course is structured by combining lectures and Journal Club-style group discussions. The course will be accompanied by “Essentials of Stem Cell Biology” (R. Lanza Ed.). Two take home exams and Journal Club participation will be the basis of student evaluations.

A solid foundation in cell biology, biochemistry and/or molecular biology is needed. Please contact the course director with questions: chris_proschel@urmc.rochester.edu

GEN 506

Draft Schedule

Spring 2020

1/16/20

Introduction

Introduction: Terminology and Definitions

1/21/20

Stem cell concepts

Stemness, assymetric division and the control of self-renewal

1/23/20

Stem cell concepts

JC

1/28/20

Stem cell concepts

iPS and related technologies

1/30/20

Stem cell concepts

Epigenetic control of differentiation

2/4/20

Tissue stem cells

JC

2/6/20

Tissue stem cells

Mesenchymal Stem Cells

2/11/20

Tissue stem cells

Stem cells of the CNS

2/13/20

Tissue stem cells

Satelite Cells

2/18/20

Tissue stem cells

Progressive lineage restriction: the hematopoetic system

2/20/20

Tissue stem cells

Microenvironmental Control of Hematopoetic Stem Cells

2/25/20

Tissue stem cells

JC

2/27/20

Tissue stem cells

Invertebrate models of stem cell biology

3/3/20

Tissue stem cells

Mesenchymal and Periosteal stem cells

3/5/20

Tissue stem cells

Germ cell stem cells

3/10/20

Tissue stem cells

Stem Cells and Lung Development and Repair

3/12/20

Tissue stem cells

iPSC models of retinal degeneration

3/17/20

Stem cells & pathology

Developmental syndromes and stem cell deficiencies

3/20/20

Stem cells & pathology

Cancer stem cells, Inc.

3/24/20

Stem cells & pathology

JC

3/26/20

Stem cells & pathology

Targeted cell-replacement: stem cells vs predifferentiation

3/31/20

Therapeutic Applications

JC

4/2/20

Therapeutic Applications

Stem cells for cardiac repair and disease modelling

4/7/20

Therapeutic Applications

JC

4/9/20

Therapeutic Applications

Stem Cells for CNS Therapy

4/14/20

Therapeutic Applications

Smart implants: biomaterials and stem cells

4/16/20

Therapeutic Applications

Stem Cells for Tendon Repair

4/21/20

Therapeutic Applications

JC

4/23/20

Therapeutic Applications

Stem cells Inc. et al. (Stem cells and Industry)

4/28/20

Stem Cells and Society

The ethics of stem cell technology.