Mahlon D. Johnson, M.D., Ph.D.

Contact Information

Phone Numbers

Office: (585) 275-3202

Fax: (585) 273-1027

A member of the University of Rochester Medical Faculty Group

An Accountable Health Partner

Not Accepting New Patients

Biography

Dr. Johnson has particular interest and expertise in neurosurgical pathology and neurodegenerative disorders. He has published extensively in peer-reviewed journals and numerous book chapters . He receives referrals for consultation from across the U.S.

Professional Background

Dr. Johnson did a residency in Anatomic Pathology, Fellowship in Neuropathology and Fellowship in Cell Biology at Vanderbilt Medical School. He was on the faculty at Vanderbilt for fifteen years becoming an Associate Professor with tenure, Director of Neuropathology and Director of the Neuropathology Training Program. He has been on the University of Rochester School of Medicine as a Professor of Neuropathology with tenure, Professor of Neurosurgery and Director of Neuropathology for over a decade. His diagnostic activities include neurosurgical and autopsy neuropathology, a consultation practice and as a consultant to the Monroe County Medical Examiner's Office. He also lectures at other medical schools. He has over 150 publications and is first author on over half.

Research

My lab studies leptomeningeal diseases especially meningeal neoplasia. Our emphasis in the past has been on identifying the role of growth factor/growth factor receptor expression and downstream signaling in the pathogenesis of meningiomas. This has included, for the first time, identifying expression and possible roles for the transforming growth factor beta superfamily, MEK-1- MAPK and PI3K-Akt pathways. We have also evaluated cerebrospinal effects on the leptomeningeal and meningioma cell proliferation. Additional studies have evaluated the expression and roles of mesothelin in the leptomeninges, metastases to the leptomeninges and in meningiomas.

Credentials

Education

1981
MD | University of Tennessee College of Medicine

1984
PHD | University of Tennessee College of Medicine

Post-doctoral Training & Residency

07/01/1989 - 06/30/1993
Fellowship in Research at Vanderbilt University Medical Center

07/01/1987 - 06/30/1989
Fellowship in Neuropathology at Vanderbilt University Medical Center

07/01/1985 - 06/30/1987
Residency in Pathology at Vanderbilt University Medical Center

09/01/1984 - 06/30/1985
Internship in Pathology at Vanderbilt University Medical Center

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Awards

2001
Pathology Residents Teaching Award, Anatomic Pathology

1984
Sigma Xi Excellence in Research Award

1982 - 1984
NIH National Research Service Award

1980
Alpha Omega Alpha Medical Honor Society

1976
NIH National Research Service Award

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Publications

Journal Articles

6/8/2023
Mays A, Byars-Winston A, Hinton A, Marshall AG, Kirabo A, August A, Marlin BJ, Riggs B, Tolbert B, Wanjalla C, Womack C, Evans CS, Barnes C, Starbird C, Williams C, Reynolds C, Taabazuing C, Cameron CE, Murray DD, Applewhite D, Morton DJ, Lee D, Williams DW, Lynch D, Brady D, Lynch E, Rutaganira FUN, Silva GM, Shuler H, Saboor IA, Davis J, Dzirasa K, Hammonds-Odie L, Reyes L, Sweetwyne MT, McReynolds MR, Johnson MDL, Smith NA, Pittman N, Ajijola OA, Smith Q, Robinson RAS, Lewis SC, Murray SA, Black S, Neal SE, Andrisse S, Townsend S, Damo SM, Griffith TN, Lambert WM, Clemons WM. "Juneteenth in STEMM and the barriers to equitable science." Cell.. 2023 Jun 8; 186(12):2510-2517. Epub 2023 Jun 08.

2/2023
Johnson MD, Rogers EJ, Khan MW, McMullen PD, Akkipeddi SMK, Mattingly T, Benesch CG, Bender MT. "Carotid Intimal Sarcoma Presenting as Large Vessel Occlusion and Diagnosed by Embolus Histopathology: Case Report." Neurology. Clinical practice.. 2023 Feb; 13(1):e200129. Epub 2023 Jan 19.

2023
Galbraith K, Vasudevaraja V, Serrano J, Shen G, Tran I, Abdallat N, Wen M, Patel S, Movahed-Ezazi M, Faustin A, Spino-Keeton M, Roberts LG, Maloku E, Drexler SA, Liechty BL, Pisapia D, Krasnozhen-Ratush O, Rosenblum M, Shroff S, Boué DR, Davidson C, Mao Q, Suchi M, North P, Hopp A, Segura A, Jarzembowski JA, Parsons L, Johnson MD, Mobley B, Samore W, McGuone D, Gopal PP, Canoll PD, Horbinski C, Fullmer JM, Farooqui MS, Gokden M, Wadhwani NR, Richardson TE, Umphlett M, Tsankova NM, DeWitt JC, Sen C, Placantonakis DG, Pacione D, Wisoff JH, Teresa Hidalgo E, Harter D, William CM, Cordova C, Kurz SC, Barbaro M, Orringer DA, Karajannis MA, Sulman EP, Gardner SL, Zagzag D, Tsirigos A, Allen JC, Golfinos JG, Snuderl M. "Clinical utility of whole-genome DNA methylation profiling as a primary molecular diagnostic assay for central nervous system tumors-A prospective study and guidelines for clinical testing." Neuro-oncology advances.. 2023 5(1):vdad076. Epub 2023 Jun 26.

Books & Chapters

2017
Chapter Title: Leptoeningeal and Dural lesions
Book Title: Neuropthologic and Neuroradiologic Correlations: A Differential Diagnostic Text and Atlas.
Author List: Hussain Ali., Johnson MD
Edited By: In Murat Godken, Manoti Kumar
Published By: Cambridge Univ. Press 2017 in London, UK

2017
Chapter Title: Meningeal Mass Lesions.
Book Title: Neuropthologic and Neuroradiologic Correlations: A Differential Diagnostic Text and Atlas.
Author List: Johnson MD, Hussain Ali.
Edited By: In Murat Goden, M Kumar
Published By: Cambridge Univ. Press 2017 in London, UK

2009
Chapter Title: Muscle and nerve biopsy
Book Title: Modern Surgical Pathology
Author List: Atkinson J.A., Johnson M.D., Bouldin, T.W. and Whetsell W.O
Edited By: Noel Weider, Richard Cote, Saul Suster, and L Weiss
Published By: W.B. Saunders 2009 in New York

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