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Mahlon D. Johnson, M.D., Ph.D.
Mahlon D. Johnson, M.D., Ph.D.

Mahlon D. Johnson, M.D., Ph.D.

Pathology/Lab Medicine — Anatomic Pathology — Anatomic Pathology

Accepting New Patients

Mahlon D. Johnson, M.D., Ph.D.

Pathology/Lab Medicine — Anatomic Pathology — Anatomic Pathology

Accepting New Patients


Locations

University of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 626
Rochester, NY 14642
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phone

Appointments

(585) 275-8762

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Fax

(585) 273-1027

About Me

Dr. Johnson has particular interest and expertise in neurosurgical pathology and neurodegenerative disorders. He has published extensively in peer-reviewed journals and receives referrals for consultation from across the U.S.

Credentials

Education:

PhD | University of Tennessee College of Medicine — 1984
MD | University of Tennessee College of Medicine — 1981

Post-doctoral Training & Residency:

Fellowship in Neuropathology at Vanderbilt University Medical Center — 1987 - 1989
Residency in Pathology at Vanderbilt University Medical Center — 1984 - 1987
Research in at Vanderbilt University School of Medicine — 1989 - 1993

Research

My lab studies leptomeningeal diseases especially meningeal neoplasia. Our emphasis in the past has been on identifying the role of growth factor/growth factor receptor expression and downstream signaling in the pathogenesis of meningiomas. This has included, for the first time, identifying expression and possible roles for the transforming growth factor beta superfamily, MEK-1- MAPK and PI3K-Akt pathways. We have also evaluated cerebrospinal effects on the leptomeningeal and meningioma cell proliferation. Additional studies have evaluated the expression and roles of mesothelin in the leptomeninges, metastases to the leptomeninges and in meningiomas.

Publications:

Liu X, Mangla R, Tian W, Qiu X, Li D, Walter KA, Ekholm S, Johnson MD. "The preliminary radiogenomics association between MR perfusion imaging parameters and genomic biomarkers, and their predictive performance of overall survival in patients with glioblastoma." Journal of neuro-oncology.. 2017 Sep 9; Epub 2017 Sep 09.

Johnson MD. "Transforming Growth Factor Beta Family in the Pathogenesis of Meningiomas." World neurosurgery.. 2017 Aug 0; 104:113-119. Epub 2017 Mar 23.

Johnson MD, O'Connell M, Walter K. "STAT3 activation and risk of recurrence in meningiomas." Oncol Lett. 2017; 13: 2432-2436.

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