Past Seminars Invited speakers provide an important opportunity for both students and faculty to learn about recent research developments from a variety of scientific disciplines. Various departments attract many nationally and internationally prominent scientists to present their work. Students are encouraged and provided opportunities to meet with each invited speaker. Angelika Amon, Massachusetts Institute of Technology "Cell cycle control in budding yeast" Philip Bevilacqua, Pennsylvania State University "Folding and catalysis of the hepatitis delta virus ribozyme" Susan M. Berget, Baylor College of Medicine "How to find an exon" Patrick Brown, Stanford University "Watching the genome come alive" Lewis Cantley, Harvard Medical School "Use of peptide libraries to deduce signal transduction pathways" Rey-Huei Chen, Cornell University "Assembly of spindle checkpoint proteins on kinetochores" Gloria M. Culver, Iowa State University "Studies of ribosome assembly" George N. DeMartino, University of Texas "Function and regulation of the proteasome: Nature’s most interesting and complex protease" George T. DeTitta, SUNY at Buffalo "High throughput crystallization for structural genomics" Maurille Fournier, University of Massachusetts,Amherst "Modified nucleotides in rRNA are important for ribosome function" Judith Frydman, Stanford University "Chaperonin-mediated folding of tumor suppressors and other proteins in the eukaryotic cytosol" Michael Grunstein, University of California, Los Angeles "Histone function in yeast: Heterochromatin and euchromatin" Barry Gumbiner, Sloan Kettering Institute "Signaling by cadherins and catenins" Jeanne Hirsch, Mount Sinai School of Medicine "Novel aspects of G protein signaling in yeast" Anita K. Hopper, Milton S. Hershey Medical Center, Pennsylvania State University "Nucleus/cytosol exchange: Genetic approaches" James Hurley, Laboratory of Molecular Biology, NIDDK "Protein machines that transduce signals: What structural biology tells us about regulation" Rohinton Kamakaka, National Institutes of Health "Histone variants, the Sir proteins and silencing in yeast" Caroline Kane, University of California, Berkeley "On the road with RNA polymerase: Regulating transcript elongation" Ron Kopito, Stanford University "How do integral membrane proteins get removed from membranes?" Gerald B. Koudelka, University of Buffalo "Allosteric effect of DNA sequence on the functions of a transciptional regulatory protein" Hiten Madhani, University of California, San Francisco "Signaling specificity and genomics in S. cerevisiae" Timothy Nilsen, Case-Western Reserve University "Trans splicing of pre-mRNA in nematodes" Jeff Roberts, Cornell University "Antitermination by phage lambda Q protein: Its relation to transcription initiation and elongation" Said Sif, Massachusetts General Hospital "Regulation of human SWI/SNF chromatin remodeling complex across the cell cycle" Michael Snyder, Yale University "Analysis of the yeast genome and proteome: A tale of two chips" Barbara Sollner-Webb, Johns Hopkins School of Medicine "Trypanosome RNA editing, a most bizarre form of RNA maturation" Alexander Sytnik, University of Pennsylvania "New insights into tRNA, ribosomes, and light-harvesting complexes via single molecule fluorescence studies" John Tainer, The Scripps Research Institute "Human repair enzyme: DNA structures and mutants reveal damaged DNA binding to stage DNA repair" Ron Taussig, University of Michigan "Genetic analysis of mammalian adenylyl cyclase" Craig Ventner, Celera Corporation "Sequencing the human genome" Jurgen Wess, Department of Bioorganic Chemistry, NIDDK, NIH "Structure function analysis of G protein-coupled receptors and their associated G protein." Fred Winston, Harvard Medical School "Analysis of histones and other transcription factors of yeast" K. Dane Wittrup, Massachusetts Institute of Technology "Directed evolution of protein recognition, stability and expression by yeast surface display" Alan Wolfe, National Institute of Child Health and Human Development "Regulatory roles for chromatin"