Skip to main content
Explore URMC


URMC / Labs / Anders Lab

M.W. (Drag) Anders

Professor Emeritus


Research Overview

During his preveterinary and veterinary training, Drag developed a deep interest in chemistry, but also enjoyed the biological side of vet medicine. After completing his D.V.M. degree, he decided not to practice and went immediately to graduate school at the University of Wisconsin. When his thesis advisor, Dr. Gilbert J. Mannering, moved to the University of Minnesota, Drag moved with him and completed his Ph.D. research there. He has held positions in the College of Veterinary Medicine at the University of Minnesota and at the New York State College of Medicine, Cornell University, Ithaca, NY. Drag returned to the Department of Pharmacology at the University of Minnesota in 1969 and remained there until 1982 when he was recruited to the University of Rochester as chair of the then Department of Pharmacology. He is presently Professor Emeritus in the Departments of Pharmacology and Physiology, of Anesthesiology, and of Environmental Medicine. Drag's research interests are focused on the metabolism and toxicity of halogen- and sulfur-containing chemicals and on the design and synthesis of mitochondrially targeted drugs.

Recent Publications

Anders MW (2012) Exploiting endobiotic metabolic pathways to target xenobiotic antioxidants to mitochondria. Mitochondrion [Epub ahead of print]

Board PG and Anders MW (2011) Glutathione transferase zeta: discovery, polymorphic variants, catalysis, inactivation, and properties of Gstz1-/- mice. Drug Metab. Rev. 43:215-225.

Anders MW (2011) Putting bioactivation reactions to work: Targeting antioxidants to mitochondria. Chem. Biol. Interact. 192:8-13.

Anders MW, Andersen ME, Clewell HJ 3rd, Gargas ML, Guengerich FP, and Reitz RH. (2010) Comment on M.V. Evans and J.C. Caldwell: evaluation of two different metabolic hypotheses for dichloromethane toxicity using physiologically based pharmacokinetic modeling of in vivo gas uptake data exposure in female B6C3F1 mice. Toxicol. Appl. Pharmacol. 248:63-64

Roser KS, Brookes PS, Wojtovich AP, Olson LP, Shojaie J, Parton RL, and Anders MW. (2010) Mitochondrial biotransformation of omega-(phenoxy)alkanoic acids, 3-(phenoxy)acrylic acids, and omega-(1-methyl-1H-imidazol-2-ylthio)alkanoic acids: a prodrug strategy for targeting cytoprotective antioxidants to mitochondria. Bioorg. Med. Chem. 18:1441-1448.

More papers