URMC / Labs / Boutz Lab / Lab Members Lab Members Principal InvestigatorPaul L. Boutz, Ph.D.MC 3-8832Phone: (585) 276-8739Email PaulResearch Interest: Regulation of pre-mRNA splicing and polyadenylation in healthy and diseased states; the contribution of RNA processing to cancer biology; effects of small molecule drugs on RNA processing and gene expression.Research StaffQuinn DoubetLaboratory Technician IIIMC 3-7537Phone: (585) 275-9331Andrew PolevodaProgrammer/AnalystMC 3-7537Phone: (585) 275-9331Graduate StudentsMohammed AliBMB - Biochemistry & Molecular Biology Ph.D. ProgramResearch Interest: Investigating differential intron sensitivity to core spliceosome factors that are amplified or deleted in developmental syndromes and cancerLeon HarveyBMB - Biochemistry & Molecular Biology Ph.D. ProgramResearch Interest: Investigating the Role of RNA Helicases in Splicing Changes caused by Cancer Associated SF3B1 MutationsXueyang HeBSCB - Biophysics, Structural & Computational Biology Ph.D. ProgramResearch Interest: Modeling the effects of cancer-associated spliceosome mutations and identifying driving intronic features using deep-learning neural networksMolly HulverBMB - Biochemistry & Molecular Biology Ph.D. ProgramResearch Interest: Modeling CDK12 and CDK13 loss-of-function (LOF) in prostate cancer cells to investigate their roles in alternative polyadenylation and neo-antigen expression