Recent Publications

• 1. Walling LR
  2. Butler JS
  Toxins targeting transfer RNAs: Translation inhibition by bacterial toxin-antitoxin systems.; Wiley interdisciplinary reviews. RNA. 2018 Sep 16.
• 1. Walling LR
  2. Butler JS
  Homologous VapC toxins inhibit translation and cell growth by sequence specific cleavage of tRNA(fMet).; Journal of bacteriology. 2017 Nov 06.
• 1. Walling LR
  2. Butler JS
  Structural determinants for antitoxin identity and insulation of cross talk between homologous toxin-antitoxin systems.; Journal of bacteriology. 2016 Sep 26.
• 1. Seward CH
  2. Manzella A
  3. Alam A
  4. Butler JS
  5. Dziejman M
  Using S. cerevisiae as a Model System to Investigate V. cholerae VopX-Host Cell Protein Interactions and Phenotypes.; Toxins; Vol 7(10). 2015 Oct.
• 1. Jin G
  2. Pavelka MS
  3. Butler JS
  Structure-function analysis of VapB4 antitoxin identifies critical features of a minimal VapC4 toxin-binding module.; Journal of bacteriology; Vol 197(7). 2015 Apr.
• 1. Hamilton B
  2. Manzella A
  3. Schmidt K
  4. DiMarco V
  5. Butler JS
  Analysis of non-typeable Haemophilous influenzae VapC1 mutations reveals structural features required for toxicity and flexibility in the active site.; PloS one; Vol 9(11). 2014.
• 1. Schmidt K
  2. Butler JS
  Nuclear RNA surveillance: role of TRAMP in controlling exosome specificity.; Wiley interdisciplinary reviews. RNA; Vol 4(2). 2013 Mar.
• 1. Schmidt K
  2. Xu Z
  3. Mathews DH
  4. Butler JS
  Air proteins control differential TRAMP substrate specificity for nuclear RNA surveillance.; RNA (New York, N.Y.); Vol 18(10). 2012 Oct.
• 1. Alam A
  2. Miller KA
  3. Chaand M
  4. Butler JS
  5. Dziejman M
  Identification of Vibrio cholerae type III secretion system effector proteins.; Infection and immunity; Vol 79(4). 2011 Apr.
• 1. Butler JS
  2. Mitchell P
  Rrp6, rrp47 and cofactors of the nuclear exosome.; Advances in experimental medicine and biology; Vol 702. 2011.
• 1. Callahan KP
  2. Butler JS
  TRAMP complex enhances RNA degradation by the nuclear exosome component Rrp6.; The Journal of biological chemistry; Vol 285(6). 2010 Feb 5.
• 1. Butler JS
  2. Mitchell P
  Rrp6, Rrp47 and cofactors of the nuclear exosome.; Advances in experimental medicine and biology; Vol 702. 2010.
• 1. Roth KM
  2. Byam J
  3. Fang F
  4. Butler JS
  Regulation of NAB2 mRNA 3'-end formation requires the core exosome and the Trf4p component of the TRAMP complex.; RNA (New York, N.Y.); Vol 15(6). 2009 Jun.
• 1. Callahan KP
  2. Butler JS
  Evidence for core exosome independent function of the nuclear exoribonuclease Rrp6p.; Nucleic acids research; Vol 36(21). 2008 Dec.
• 1. Hoskins J
  2. Butler JS
  RNA-based 5-fluorouracil toxicity requires the pseudouridylation activity of Cbf5p.; Genetics; Vol 179(1). 2008 May.
• 1. Callahan KP
  2. Butler JS
  Lifting the veil on the transcriptome.; Genome biology; Vol 9(4). 2008.
• 1. Fang F
  2. Phillips S
  3. Butler JS
  Rat1p and Rai1p function with the nuclear exosome in the processing and degradation of rRNA precursors.; RNA (New York, N.Y.); Vol 11(10). 2005 Oct.
• 1. Roth KM
  2. Wolf MK
  3. Rossi M
  4. Butler JS
  The nuclear exosome contributes to autogenous control of NAB2 mRNA levels.; Molecular and cellular biology; Vol 25(5). 2005 Mar.
• 1. Fang F
  2. Hoskins J
  3. Butler JS
  5-fluorouracil enhances exosome-dependent accumulation of polyadenylated rRNAs.; Molecular and cellular biology; Vol 24(24). 2004 Dec.
• 1. Kuai L
  2. Fang F
  3. Butler JS
  4. Sherman F
  Polyadenylation of rRNA in Saccharomyces cerevisiae.; Proceedings of the National Academy of Sciences of the United States of America; Vol 101(23). 2004 Jun 8.
• 1. Lum PY
  2. Armour CD
  3. Stepaniants SB
  4. Cavet G
  5. Wolf MK
  6. Butler JS
  7. Hinshaw JC
  8. Garnier P
  9. Prestwich GD
  10. Leonardson A
  11. Garrett-Engele P
  12. Rush CM
  13. Bard M
  14. Schimmack G
  15. Phillips JW
  16. Roberts CJ
  17. Shoemaker DD
  Discovering modes of action for therapeutic compounds using a genome-wide screen of yeast heterozygotes.; Cell; Vol 116(1). 2004 Jan 9.
• 1. Phillips S
  2. Butler JS
  Contribution of domain structure to the RNA 3' end processing and degradation functions of the nuclear exosome subunit Rrp6p.; RNA (New York, N.Y.); Vol 9(9). 2003 Sep.
• 1. Das B
  2. Butler JS
  3. Sherman F
  Degradation of normal mRNA in the nucleus of Saccharomyces cerevisiae.; Molecular and cellular biology; Vol 23(16). 2003 Aug.
• 1. Butler JS
  The yin and yang of the exosome.; Trends in cell biology; Vol 12(2). 2002 Feb.
• 1. Burkard KT
  2. Butler JS
  A nuclear 3'-5' exonuclease involved in mRNA degradation interacts with Poly(A) polymerase and the hnRNA protein Npl3p.; Molecular and cellular biology; Vol 20(2). 2000 Jan.
• 1. Briggs MW
  2. Burkard KT
  3. Butler JS
  Rrp6p, the yeast homologue of the human PM-Scl 100-kDa autoantigen, is essential for efficient 5.8 S rRNA 3' end formation.; The Journal of biological chemistry; Vol 273(21). 1998 May 22.
• 1. Liang S
  2. Briggs MW
  3. Butler JS
  Regulation of tRNA suppressor activity by an intron-encoded polyadenylation signal.; RNA (New York, N.Y.); Vol 3(6). 1997 Jun.
• 1. Proweller A
  2. Butler JS
  Ribosome concentration contributes to discrimination against poly(A)- mRNA during translation initiation in Saccharomyces cerevisiae.; The Journal of biological chemistry; Vol 272(9). 1997 Feb 28.
• 1. Briggs MW
  2. Butler JS
  RNA polymerase III defects suppress a conditional-lethal poly(A) polymerase mutation in Saccharomyces cerevisiae.; Genetics; Vol 143(3). 1996 Jul.
• 1. Proweller A
  2. Butler JS
  Ribosomal association of poly(A)-binding protein in poly(A)-deficient Saccharomyces cerevisiae.; The Journal of biological chemistry; Vol 271(18). 1996 May 3.
• 1. Guo Z
  2. Russo P
  3. Yun DF
  4. Butler JS
  5. Sherman F
  Redundant 3' end-forming signals for the yeast CYC1 mRNA.; Proceedings of the National Academy of Sciences of the United States of America; Vol 92(10). 1995 May 9.
• 1. Proweller A
  2. Butler S
  Efficient translation of poly(A)-deficient mRNAs in Saccharomyces cerevisiae.; Genes & development; Vol 8(21). 1994 Nov 1.
• 1. Patel D
  2. Butler JS
  Conditional defect in mRNA 3' end processing caused by a mutation in the gene for poly(A) polymerase.; Molecular and cellular biology; Vol 12(7). 1992 Jul.
• 1. Sadhale PP
  2. Sapolsky R
  3. Davis RW
  4. Butler JS
  5. Platt T
  Polymerase chain reaction mapping of yeast GAL7 mRNA polyadenylation sites demonstrates that 3' end processing in vitro faithfully reproduces the 3' ends observed in vivo.; Nucleic acids research; Vol 19(13). 1991 Jul 11.
• 1. Butler JS
  2. Sadhale PP
  3. Platt T
  RNA processing in vitro produces mature 3' ends of a variety of Saccharomyces cerevisiae mRNAs.; Molecular and cellular biology; Vol 10(6). 1990 Jun.
• 1. Butler JS
  2. Platt T
  RNA processing generates the mature 3' end of yeast CYC1 messenger RNA in vitro.; Science (New York, N.Y.); Vol 242(4883). 1988 Dec 2.
• 1. Butler JS
  2. Springer M
  3. Grunberg-Manago M
  AUU-to-AUG mutation in the initiator codon of the translation initiation factor IF3 abolishes translational autocontrol of its own gene (infC) in vivo.; Proceedings of the National Academy of Sciences of the United States of America; Vol 84(12). 1987 Jun.
• 1. Butler JS
  2. Springer M
  3. Dondon J
  4. Graffe M
  5. Grunberg-Manago M
  Escherichia coli protein synthesis initiation factor IF3 controls its own gene expression at the translational level in vivo.; Journal of molecular biology; Vol 192(4). 1986 Dec 20.
• 1. Springer M
  2. Graffe M
  3. Butler JS
  4. Grunberg-Manago M
  Genetic definition of the translational operator of the threonine-tRNA ligase gene in Escherichia coli.; Proceedings of the National Academy of Sciences of the United States of America; Vol 83(12). 1986 Jun.
• 1. Butler JS
  2. Springer M
  3. Dondon J
  4. Grunberg-Manago M
  Posttranscriptional autoregulation of Escherichia coli threonyl tRNA synthetase expression in vivo.; Journal of bacteriology; Vol 165(1). 1986 Jan.
• 1. Springer M
  2. Plumbridge JA
  3. Butler JS
  4. Graffe M
  5. Dondon J
  6. Mayaux JF
  7. Fayat G
  8. Lestienne P
  9. Blanquet S
  10. Grunberg-Manago M
  Autogenous control of Escherichia coli threonyl-tRNA synthetase expression in vivo.; Journal of molecular biology; Vol 185(1). 1985 Sep 5.
• 1. Butler JS
  2. Clark JM
  Eucaryotic initiation factor 4B of wheat germ binds to the translation initiation region of a messenger ribonucleic acid.; Biochemistry; Vol 23(5). 1984 Feb 28.