Coppage Lab
Welcome to the Coppage Lab
The Coppage laboratory has both clinical and basic science arms. Clinically the laboratory studies the antibodies involved in antibody mediated rejection, using qualitative and semiquantitative analyses. The basic science arm is an interest in the phenomenon of accommodation to antibody by endothelium in the transplant setting.
Dr. Coppage also actively collaborates with Dr. Jane Liesveld, clinical director of a blood and stem cell transplant program. Their interests include study of the bone marrow niche in hematological malignancies. This includes the culture, identification and manipulation of cellular components of the marrow niche (stromal cells, endothelial cells, mesenchymal and hematopoitic stem cells).
Myra L. Coppage, Ph.D.
Principal Investigator
Publications
View All Publications- Non-donor specific anti-human leukocyte antigen (HLA) antibodies are not associated with poor outcome in hematopoietic stem cell transplant recipients.; Human immunology; Vol 81(8). 2020 Aug.
- Bone marrow mesenchymal stromal cells from acute myelogenous leukemia patients demonstrate adipogenic differentiation propensity with implications for leukemia cell support.; Leukemia. 2019 Sep 06.
- Effects of Neddylation and mTOR Inhibition in Acute Myelogenous Leukemia.; Translational oncology; Vol 12(4). 2019 Jan 27.
- HLA-Mediated Platelet Refractoriness: An ACLPS Critical Review.; American journal of clinical pathology. 2018 Oct 03.
- Phenotypic, genotypic, and functional characterization of normal and acute myeloid leukemia-derived marrow endothelial cells.; Experimental hematology; Vol 44(5). 2016 May.
- Leukemia specific loss of heterozygosity of MHC in a CLL patient: disease state impacts timing of confirmatory typing.; Human immunology; Vol 74(1). 2013 Jan.
Affiliations
Contact Us
Coppage Lab
601 Elmwood Ave, Box 608
Rochester, NY 14642