Welcome to the Dalecki Lab
The Dalecki Laboratory is dedicated to advancing the use of ultrasound in medicine and biology. Primary goals of the laboratory are to advance novel diagnostic ultrasound techniques, and to discover and develop new therapeutic applications of ultrasound. Research in the Dalecki Laboratory is highly multidisciplinary and spans the fields of biomedical ultrasound, acoustics, medical imaging, cell and tissue engineering, regenerative medicine, biomaterials, and biomechanics. Areas of focus in our laboratory include:
- Ultrasound Technologies for Tissue Engineering and Regenerative Medicine
- Therapeutic Applications of Ultrasound
- High-Frequency Quantitative Ultrasound for Biomaterials Characterization
- Diagnostic Ultrasound
In the Dalecki Lab, efforts concentrate on identifying the molecular, cellular, physiological, and physical mechanisms for the interaction of ultrasound fields with biological tissues. Knowledge of basic mechanisms facilitates the safe and effective development of new diagnostic and therapeutic ultrasound techniques. Current research in the laboratory is focused on innovating ultrasound-based technologies for the fabrication of engineered tissues and biomaterials, and on enhancing tissue regeneration and soft-tissue wound healing. In concert, research in the Dalecki Lab is dedicated to innovating a suite of high-frequency, quantitative ultrasound imaging techniques to non-invasively characterize the structure, mechanical properties, and function of native and engineered tissues.
Diane Dalecki, PhD is the Kevin J. Parker Distinguished Professor in Biomedical Engineering, and Professor of Electrical and Computer Engineering at the University of Rochester. She is also the Director of the Rochester Center for Biomedical Ultrasound, a multi-disciplinary center dedicated to advancing biomedical ultrasound for imaging and therapy, and she is the Past Chair of the Department of Biomedical Engineering at the University of Rochester. Professor Dalecki’s laboratory is dedicated to advancing novel diagnostic ultrasound imaging techniques, and to discovering and developing new therapeutic applications of ultrasound for medicine, biology, and biotechnology. A particular focus of her laboratory is on advancing innovative ultrasound technologies for tissue engineering and regenerative medicine. As an internationally recognized leader in biomedical ultrasound, Professor Dalecki is a Fellow of the American Institute of Ultrasound in Medicine (AIUM), a Fellow of the Acoustical Society of America (ASA), and a Fellow of the American Institute of Medical and Biological Engineering (AIMBE). Professor Dalecki completed her BS in chemical engineering, and MS and PhD in electrical engineering all from the University of Rochester.

Diane Dalecki, Ph.D.
Principal Investigator
Projects
View All ProjectsPublications
View All Publications- Characterizing tendon microstructure using metrics associated with the angular dependence of ultrasound backscatter.; The Journal of the Acoustical Society of America; Vol 159(4), pp. 3311-3322. 2026 Apr 01.
- Overview of Therapeutic Ultrasound Applications and Safety Considerations: 2024 Update.; Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine. 2024 Nov 11.
- In vivo acoustic patterning of endothelial cells for tissue vascularization.; Scientific reports; Vol 13(1), pp. 16082. 2023 Sep 26.
- Phase holograms for the three-dimensional patterning of unconstrained microparticles.; Scientific reports; Vol 13(1), pp. 9160. 2023 Jun 06.
- Time- and Dose-Dependent Effects of Pulsed Ultrasound on Dermal Repair in Diabetic Mice.; Ultrasound in medicine & biology. 2021 Jan 13.
- Diagnostic Ultrasound Safety Review for Point-of-Care Ultrasound Practitioners.; Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine; Vol 39(6). 2020 Jun.
- Acoustic Fabrication of Collagen-Fibronectin Composite Gels Accelerates Microtissue Formation.; Applied sciences (Basel, Switzerland); Vol 10(8). 2020 Apr 02.
- Using Acoustic Fields to Fabricate ECM-Based Biomaterials for Regenerative Medicine Applications.; Recent progress in materials; Vol 2(3). 2020.
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Dalecki Lab
Goergen Hall 336
Rochester, NY 14627
(585) 276-1999