Recent Publications
Recent Publications
- Comparison of Experimental Approaches Used to Determine the Structure and Function of the Class D G Protein-Coupled Yeast α-Factor Receptor.; Biomolecules; Vol 12(6). 2022 May 30.
- Oligomerization of Yeast α-factor Receptor Detected by Fluorescent Energy Transfer Between Ligands.; Biophysical journal. 2021 Oct 07.
- Identification of variant HIV envelope proteins with enhanced affinities for precursors to anti-gp41 broadly neutralizing antibodies.; PloS one; Vol 14(9). 2019.
- Display of the HIV envelope protein at the yeast cell surface for immunogen development.; PloS one; Vol 13(10). 2018.
- Human CaaX protease ZMPSTE24 expressed in yeast: Structure and inhibition by HIV protease inhibitors.; Protein science : a publication of the Protein Society; Vol 26(2). 2017 Feb.
- Structure of the SLC4 transporter Bor1p in an inward-facing conformation.; Protein science : a publication of the Protein Society; Vol 26(1). 2017 Jan.
- Variable Dependence of Signaling Output on Agonist Occupancy of Ste2p, a G Protein Coupled Receptor in Yeast.; The Journal of biological chemistry. 2016 Sep 19.
- Deducing the Symmetry of Helical Assemblies: Applications to Membrane Proteins.; Journal of structural biology. 2016 May 30.
- The Crystal Structure of an Integral Membrane Fatty Acid α-Hydroxylase.; The Journal of biological chemistry; Vol 290(50). 2015 Dec 11.
- Identification of destabilizing and stabilizing mutations of Ste2p, a G protein-coupled receptor in Saccharomyces cerevisiae.; Biochemistry; Vol 54(9). 2015 Mar 10.
- A Novel Screening Approach for Optimal and Functional Fusion of T4 Lysozyme in GPCRs.; Methods in enzymology; Vol 557. 2015.
- Guided reconstitution of membrane protein fragments.; Biopolymers; Vol 102(1). 2014 Jan.
- Fluorescent approaches for understanding interactions of ligands with G protein coupled receptors.; Biochimica et biophysica acta; Vol 1838(1 Pt A). 2014 Jan.
- Structure of the integral membrane protein CAAX protease Ste24p.; Science (New York, N.Y.); Vol 339(6127). 2013 Mar 29.
- Coordinating the impact of structural genomics on the human α-helical transmembrane proteome.; Nature structural & molecular biology; Vol 20(2). 2013 Feb.
- Functional fusions of T4 lysozyme in the third intracellular loop of a G protein-coupled receptor identified by a random screening approach in yeast.; Protein engineering, design & selection : PEDS; Vol 26(1). 2013 Jan.
- Functional and physical interactions among Saccharomyces cerevisiae α-factor receptors.; Eukaryotic cell; Vol 11(10). 2012 Oct.
- Nanochannel-based single molecule recycling.; Nano letters; Vol 12(6). 2012 Jun 13.
- Identifying functionally important conformational changes in proteins: activation of the yeast α-factor receptor Ste2p.; Journal of molecular biology; Vol 418(5). 2012 May 18.
- Oligomeric state of the oxalate transporter, OxlT.; Biochemistry; Vol 50(39). 2011 Oct 4.
- Differential interactions of fluorescent agonists and antagonists with the yeast G protein coupled receptor Ste2p.; Journal of molecular biology; Vol 409(4). 2011 Jun 17.
- Binding of fluorinated phenylalanine alpha-factor analogues to Ste2p: evidence for a cation-pi binding interaction between a peptide ligand and its cognate G protein-coupled receptor.; Biochemistry; Vol 49(24). 2010 Jun 22.
- Purification of transmembrane proteins from Saccharomyces cerevisiae for X-ray crystallography.; Protein expression and purification; Vol 71(2). 2010 Jun.
- Identification of human gene products containing Pro-Pro-x-Tyr (PY) motifs that enhance glutathione and endocytotic marker uptake in yeast.; Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology; Vol 25(2-3). 2010.
- Expression of 25 human ABC transporters in the yeast Pichia pastoris and characterization of the purified ABCC3 ATPase activity.; Biochemistry; Vol 46(27). 2007 Jul 10.
- Role of extracellular charged amino acids in the yeast alpha-factor receptor.; Biochimica et biophysica acta; Vol 1773(6). 2007 Jun.
- Characteristics affecting expression and solubilization of yeast membrane proteins.; Journal of molecular biology; Vol 365(3). 2007 Jan 19.
- Purification and ATP hydrolysis of the putative cholesterol transporters ABCG5 and ABCG8.; Biochemistry; Vol 45(32). 2006 Aug 15.
- Oligomerization of the yeast alpha-factor receptor: implications for dominant negative effects of mutant receptors.; The Journal of biological chemistry; Vol 281(30). 2006 Jul 28.
- Biochemical and genetic analysis of the yeast proteome with a movable ORF collection.; Genes & development; Vol 19(23). 2005 Dec 1.
- A fluorescent alpha-factor analogue exhibits multiple steps on binding to its G protein coupled receptor in yeast.; Biochemistry; Vol 43(42). 2004 Oct 26.
- A facile method for high-throughput co-expression of protein pairs.; Molecular & cellular proteomics : MCP; Vol 3(9). 2004 Sep.
- Effects of mutations in the N terminal region of the yeast G protein alpha-subunit Gpa1p on signaling by pheromone receptors.; Molecular genetics and genomics : MGG; Vol 271(2). 2004 Mar.
- Intensive mutational analysis of G protein-coupled receptors in yeast.; Methods in molecular biology (Clifton, N.J.); Vol 237. 2004.
- Sequences in the intracellular loops of the yeast pheromone receptor Ste2p required for G protein activation.; Biochemistry; Vol 42(10). 2003 Mar 18.
- Effects of Inserting Intracellular Loops of the Yeast a-factor Receptor, Ste3p, into the a-factor Receptor, Ste2p; Yeast. 2003 Jan 01.
- Biosynthesis and Biophysical Analysis of Domains of a Yeast G protein-coupled receptor; Biopolymers (Peptide Science). 2003 Jan 01.
- Mutagenic mapping of helical structures in the transmembrane segments of the yeast alpha-factor receptor.; Journal of molecular biology; Vol 317(5). 2002 Apr 12.
- Single amino acid substitutions and deletions that alter the G protein coupling properties of the V2 vasopressin receptor identified in yeast by receptor random mutagenesis.; The Journal of biological chemistry; Vol 276(31). 2001 Aug 3.
- A limited spectrum of mutations causes constitutive activation of the yeast alpha-factor receptor.; Biochemistry; Vol 39(23). 2000 Jun 13.
- Dominant negative mutations in the alpha-factor receptor, a G protein-coupled receptor encoded by the STE2 gene of the yeast Saccharomyces cerevisiae.; Molecular & general genetics : MGG; Vol 261(6). 1999 Jul.
- Assembly of G protein-coupled receptors from fragments: identification of functional receptors with discontinuities in each of the loops connecting transmembrane segments.; Biochemistry; Vol 38(2). 1999 Jan 12.
- Genetic Approaches for Studying the Structure and Function of G Protein-Coupled receptors in Yeast in Structure-Function Analysis of G Protein-Coupled Receptors; ( J. Wess, ed.) Vol. III of Receptor Biochemistry and Methodology, , John Wiley and Sons, New York. 1999 Jan 01.
- ATP-dependent transport of reduced glutathione on YCF1, the yeast orthologue of mammalian multidrug resistance associated proteins.; The Journal of biological chemistry; Vol 273(50). 1998 Dec 11.
- ATP-dependent transport of reduced glutathione in yeast secretory vesicles.; The Biochemical journal; Vol 334 ( Pt 3). 1998 Sep 15.
- Bacterial expression of a mitochondrial cytochrome c. Trimethylation of lys72 in yeast iso-1-cytochrome c and the alkaline conformational transition.; Biochemistry; Vol 37(17). 1998 Apr 28.
- Genetic interactions among the transmembrane segments of the G protein coupled receptor encoded by the yeast STE2 gene.; Journal of molecular biology; Vol 266(3). 1997 Feb 28.
- Sequence requirements for mitochondrial import of yeast cytochrome c.; The Journal of biological chemistry; Vol 271(12). 1996 Mar 22.
- Noncovalent binding of heme induces a compact apocytochrome c structure.; Biochemistry; Vol 33(23). 1994 Jun 14.
- CYC2 encodes a factor involved in mitochondrial import of yeast cytochrome c.; Molecular and cellular biology; Vol 13(10). 1993 Oct.