URMC / Labs / Dunman Lab / Publications Publications Choby JEMike LAMashruwala AADutter BFDunman PMSulikowski GABoyd JMSkaar EP (2016 Nov 17). A Small-Molecule Inhibitor of Iron-Sulfur Cluster Assembly Uncovers a Link between Virulence Regulation and Metabolism in Staphylococcus aureus. Cell chemical biology. Blanchard CBrooks LEbsworth-Mojica KDidione LWucher BDewhurst SKrysan DDunman PMWozniak RA (2016 Sep). Zinc Pyrithione Improves the Antibacterial Activity of Silver Sulfadiazine Ointment. mSphere. Blanchard CBrooks LBeckley AColquhoun JDewhurst SDunman PM (2016 Feb). Neomycin Sulfate Improves the Antimicrobial Activity of Mupirocin-Based Antibacterial Ointments. Antimicrobial agents and chemotherapy. Wilde ADSnyder DJPutnam NEValentino MDHammer NDLonergan ZRHinger SAAysanoa EEBlanchard CDunman PMWasserman GAChen JShopsin BGilmore MSSkaar EPCassat JE (2015 Dec). Bacterial Hypoxic Responses Revealed as Critical Determinants of the Host-Pathogen Outcome by TnSeq Analysis of Staphylococcus aureus Invasive Infection. PLoS pathogens. Sheehan LMBudnick JABlanchard CDunman PMCaswell CC (2015 Oct). A LysR-family transcriptional regulator required for virulence in Brucella abortus is highly conserved among the α-proteobacteria. Molecular microbiology. Tomaras APDunman PM (2015 Oct). In the midst of the antimicrobial discovery conundrum: an overview. Current opinion in microbiology. Dunman PMTomaras AP (2015 Oct). Translational deficiencies in antibacterial discovery and new screening paradigms. Current opinion in microbiology. Dunman PMTomaras AP (2015 Oct). Editorial overview: Antimicrobials. Current opinion in microbiology. Eidem TMLounsbury NEmery JFBulger JSmith AAbou-Gharbia MChilders WDunman PM (2015 Apr). Small-molecule inhibitors of Staphylococcus aureus RnpA-mediated RNA turnover and tRNA processing. Antimicrobial agents and chemotherapy. Mootz JMBenson MAHeim CECrosby HAKavanaugh JSDunman PMKielian TTorres VJHorswill AR (2015 Apr). Rot is a key regulator of Staphylococcus aureus biofilm formation. Molecular microbiology. Forbes LEbsworth-Mojica KDiDone LLi SGFreundlich JSConnell NDunman PMKrysan DJ (2015). A High Throughput Screening Assay for Anti-Mycobacterial Small Molecules Based on Adenylate Kinase Release as a Reporter of Cell Lysis. PloS one. Colquhoun JMWozniak RADunman PM (2015). Clinically Relevant Growth Conditions Alter Acinetobacter baumannii Antibiotic Susceptibility and Promote Identification of Novel Antibacterial Agents. PloS one. Blanchard CBarnett PPerlmutter JDunman PM (2014 Nov). Identification of Acinetobacter baumannii serum-associated antibiotic efflux pump inhibitors. Antimicrobial agents and chemotherapy. Perlmutter JIForbes LTKrysan DJEbsworth-Mojica KColquhoun JMWang JLDunman PMFlaherty DP (2014 Oct 23). Repurposing the antihistamine terfenadine for antimicrobial activity against Staphylococcus aureus. Journal of medicinal chemistry. Olson METodd DASchaeffer CRPaharik AEVan Dyke MJBüttner HDunman PMRohde HCech NBFey PDHorswill AR (2014 Oct). Staphylococcus epidermidis agr quorum-sensing system: signal identification, cross talk, and importance in colonization. Journal of bacteriology. Lindgren JKThomas VCOlson MEChaudhari SSNuxoll ASSchaeffer CRLindgren KEJones JZimmerman MCDunman PMBayles KWFey PD (2014 Jun). Arginine deiminase in Staphylococcus epidermidis functions to augment biofilm maturation through pH homeostasis. Journal of bacteriology. Eidem TMCoughlan ATowler MRDunman PMWren AW (2014 Apr). Drug-eluting cements for hard tissue repair: a comparative study using vancomycin and RNPA1000 to inhibit growth of Staphylococcus aureus. Journal of biomaterials applications. Jacobs ACBlanchard CECatherman SCDunman PMMurata Y (2014). An ribonuclease T2 family protein modulates Acinetobacter baumannii abiotic surface colonization. PloS one. Hanses FRoux CDunman PMSalzberger BLee JC (2014). Staphylococcus aureus gene expression in a rat model of infective endocarditis. Genome medicine. Scherr TDRoux CMHanke MLAngle ADunman PMKielian T (2013 Dec). Global transcriptome analysis of Staphylococcus aureus biofilms in response to innate immune cells. Infection and immunity. Easterhoff DOntiveros FBrooks LRKim YRoss BSilva JNOlsen JSFeng CHardy DJDunman PMDewhurst S (2013 Jun). Semen-derived enhancer of viral infection (SEVI) binds bacteria, enhances bacterial phagocytosis by macrophages, and can protect against vaginal infection by a sexually transmitted bacterial pathogen. Antimicrobial agents and chemotherapy. Caswell CCElhassanny AEPlanchin EERoux CMWeeks-Gorospe JNFicht TADunman PMRoop RM (2013 Apr). Diverse genetic regulon of the virulence-associated transcriptional regulator MucR in Brucella abortus 2308. Infection and immunity. Hood MIBecker KWRoux CMDunman PMSkaar EP (2013 Feb). genetic determinants of intrinsic colistin tolerance in Acinetobacter baumannii. Infection and immunity. Jacobs ACDidone LJobson JSofia MKKrysan DDunman PM (2013 Jan). Adenylate kinase release as a high-throughput-screening-compatible reporter of bacterial lysis for identification of antibacterial agents. Antimicrobial agents and chemotherapy. Brinkman CLBumgarner RKittichotirat WDunman PMKuechenmeister LJWeaver KE (2013 Jan). Characterization of the effects of an rpoC mutation that confers resistance to the Fst peptide toxin-antitoxin system toxin. Journal of bacteriology. Price-Whelan APoon CKBenson MAEidem TTRoux CMBoyd JMDunman PMTorres VJKrulwich TA (2013). Transcriptional profiling of Staphylococcus aureus during growth in 2 M NaCl leads to clarification of physiological roles for Kdp and Ktr K+ uptake systems. mBio. Kinkel TLRoux CMDunman PMFang FC (2013). The Staphylococcus aureus SrrAB two-component system promotes resistance to nitrosative stress and hypoxia. mBio. Annadurai SMartinez RCanney DJEidem TDunman PMAbou-Gharbia M (2012 Dec 15). Design and synthesis of 2-aminothiazole based antimicrobials targeting MRSA. Bioorganic & medicinal chemistry letters. Anbalagan SDmitriev AMcShan WMDunman PMChaussee MS (2012 Aug). Growth phase-dependent modulation of Rgg binding specificity in Streptococcus pyogenes. Journal of bacteriology. Caswell CCGaines JMCiborowski PSmith DBorchers CHRoux CMSayood KDunman PMRoop Ii RM (2012 Jul). Identification of two small regulatory RNAs linked to virulence in Brucella abortus 2308. Molecular microbiology. Morrison JMMiller EWBenson MAAlonzo FYoong PTorres VJHinrichs SHDunman PM (2012 Jun). Characterization of SSR42, a novel virulence factor regulatory RNA that contributes to the pathogenesis of a Staphylococcus aureus USA300 representative. Journal of bacteriology. Eidem TMRoux CMDunman PM (2012 May). RNA decay: a novel therapeutic target in bacteria. Wiley interdisciplinary reviews. RNA. Jacobs ACSayood KOlmsted SBBlanchard CEHinrichs SRussell DDunman PM (2012 Apr). Characterization of the Acinetobacter baumannii growth phase-dependent and serum responsive transcriptomes. FEMS immunology and medical microbiology. Gardete SKim CHartmann BMMwangi MRoux CMDunman PMChambers HFTomasz A (2012 Feb). Genetic pathway in acquisition and loss of vancomycin resistance in a methicillin resistant Staphylococcus aureus (MRSA) strain of clonal type USA300. PLoS pathogens. Morrison JMAnderson KLBeenken KESmeltzer MSDunman PM (2012). The staphylococcal accessory regulator, SarA, is an RNA-binding protein that modulates the mRNA turnover properties of late-exponential and stationary phase Staphylococcus aureus cells. Frontiers in cellular and infection microbiology. Truong-Bolduc QCDunman PMEidem THooper DC (2011 Nov). Transcriptional profiling analysis of the global regulator NorG, a GntR-like protein of Staphylococcus aureus. Journal of bacteriology. Roux CMDeMuth JPDunman PM (2011 Oct). Characterization of components of the Staphylococcus aureus mRNA degradosome holoenzyme-like complex. Journal of bacteriology. Lei MGCue DRoux CMDunman PMLee CY (2011 Oct). Rsp inhibits attachment and biofilm formation by repressing fnbA in Staphylococcus aureus MW2. Journal of bacteriology. Morrison JMDunman PM (2011 Oct). The modulation of Staphylococcus aureus mRNA turnover. Future microbiology. Anbalagan SMcShan WMDunman PMChaussee MS (2011 Sep). Identification of Rgg binding sites in the Streptococcus pyogenes chromosome. Journal of bacteriology. Luong TTSau KRoux CSau SDunman PMLee CY (2011 Feb). Staphylococcus aureus ClpC divergently regulates capsule via sae and codY in strain newman but activates capsule via codY in strain UAMS-1 and in strain Newman with repaired saeS. Journal of bacteriology. Olson PDKuechenmeister LJAnderson KLDaily SBeenken KERoux CMReniere MLLewis TLWeiss WJPulse MNguyen PSimecka JWMorrison JMSayood KAsojo OASmeltzer MSSkaar EPDunman PM (2011). Small molecule inhibitors of Staphylococcus aureus RnpA alter cellular mRNA turnover, exhibit antimicrobial activity, and attenuate pathogenesis. PLoS pathogens. Anderson KLRoux CMOlson MWLuong TTLee CYOlson RDunman PM (2010 Dec). Characterizing the effects of inorganic acid and alkaline shock on the Staphylococcus aureus transcriptome and messenger RNA turnover. FEMS immunology and medical microbiology. Wyatt MAWang WRoux CMBeasley FCHeinrichs DEDunman PMMagarvey NA (2010 Jul 16). Staphylococcus aureus nonribosomal peptide secondary metabolites regulate virulence. Science (New York, N.Y.). Majerczyk CDDunman PMLuong TTLee CYSadykov MRSomerville GABodi KSonenshein AL (2010 Jun). Direct targets of CodY in Staphylococcus aureus. Journal of bacteriology. Lan LCheng ADunman PMMissiakas DHe C (2010 Jun). Golden pigment production and virulence gene expression are affected by metabolisms in Staphylococcus aureus. Journal of bacteriology. Jacobs ACHood IBoyd KLOlson PDMorrison JMCarson SSayood KIwen PCSkaar EPDunman PM (2010 May). Inactivation of phospholipase D diminishes Acinetobacter baumannii pathogenesis. Infection and immunity. Torres VJAttia ASMason WJHood MICorbin BDBeasley FCAnderson KLStauff DLMcDonald WHZimmerman LJFriedman DBHeinrichs DEDunman PMSkaar EP (2010 Apr). Staphylococcus aureus fur regulates the expression of virulence factors that contribute to the pathogenesis of pneumonia. Infection and immunity. Hood MIJacobs ACSayood KDunman PMSkaar EP (2010 Mar). Acinetobacter baumannii increases tolerance to antibiotics in response to monovalent cations. Antimicrobial agents and chemotherapy. Kuhn GKoessler TMelles DCFrancois PHuyghe ADunman PVos MCZanetti GSchrenzel Jvan Belkum ABlanc DS (2010 Jan). Comparative genomics of epidemic versus sporadic Staphylococcus aureus strains does not reveal molecular markers for epidemicity. Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases.