Welcome to the Pain and Perceptions Lab
The Pain and Perceptions Lab focuses on pain and hedonic perceptions. We are interested in understanding the neural mechanisms that transform nociceptive input to painful perceptions in humans and how these mechanisms change in chronic pain. Pain and nociception are closely related to somatosensory (e.g., touch) and hedonic perceptions and therefore we also study such experiences with the aim of disentangling pain from non-painful perception and understanding how hedonic perception goes awry in chronic pain patients.
Paul Geha, M.D.
Principal Investigator
Publications
View All Publications- Loss of effort in chronic low-back pain patients: Motivational anhedonia in chronic pain.; PloS one; Vol 20(8), pp. e0317980. 2025 Aug 20.
- Resting-State Brain Activity in Acute and Chronic Complex Regional Pain Syndrome.; The European journal of neuroscience; Vol 62(3), pp. e70220. 2025 Aug.
- Dopaminergic modulation: revisiting a promising novel pathway for pharmacologic treatment of chronic pain.; Pain. 2025 Apr 25.
- The inflammatory and genetic mechanisms underlying the cumulative effect of co-occurring pain conditions on depression.; Science advances; Vol 11(14), pp. eadt1083. 2025 Apr 02.
- Turning Patients' Open-Ended Narratives of Chronic Pain into Quantitative Measures: A Natural Language Processing Study; JMIR-HUMAN FACTOR; Vol Accepted. 2025 Jan 01.
- Clinical Phenotype Matters: Structural and Functional Thalamic Changes in Neuropathic Low-Back Pain; PAIN; Vol Accepted. 2025 Jan 01.
Affiliations
Contact Us
Pain and Perceptions Lab
430 Elmwood Ave
Rochester, NY 14620