URochester Medicine / Labs / Georas Lab / Publications

Recent Publications

1. Georas SN
2. Bourdin A
IL-33 blockade in asthma: a story of hype, hope and hindsight.; ERJ open research; Vol 12(1). 2026 Feb 23.
1. Denlinger LC
2. Israel E
3. Moore WC
4. Georas SN
5. Wright RJ
6. Castro M
7. Peden DB
8. Anstrom KJ
9. Bleecker ER
10. Alexander LC
11. Cahill KN
12. Cardet JC
13. Carr TF
14. Cedano J
15. Chen AY
16. Chupp GL
17. Comhair SAA
18. DiMango EA
19. Erzurum SC
20. Fahy JV
21. Fajt ML
22. Gaston BM
23. Jackson DJ
24. Jain S
25. Jarjour NN
26. Kenyon NJ
27. Kraft M
28. Krishnan JA
29. Kumar R
30. Lugogo NL
31. Martinez FD
32. Marquis MA
33. Pappalardo AA
34. Phipatanakul W
35. Rank MA
36. Rosenberg SR
37. Salciccioli JD
38. Sanchez M
39. Smith LJ
40. Sumino K
41. Szefler SJ
42. Tang M
43. Vijayanand P
44. Wechsler ME
45. Wenzel SE
46. White SR
47. Zeki AA
48. Ivanova A
49. Bacharier LB
50. Akuthota P
PrecISE- A Biomarker Stratified Adaptive Trial of 5 Interventions in Severe Asthma: Final Protocol and the Baseline Cohort.; The Journal of allergy and clinical immunology. 2026 Feb 16.
1. Agache I
2. Zemelka-Wiacek M
3. Gawlik R
4. Georas SN
5. Jahnz-Różyk K
6. Kupczyk M
7. Moniuszko M
8. Mӧsges R
9. Mukherjee M
10. Nair P
11. Papi A
12. Sanak M
13. Ӧnder Yldirim A
14. Jutel M
Targeted treatment in asthma - opportunities and challenges.; The journal of allergy and clinical immunology. In practice. 2025 Nov 26.
1. Merrell E
2. Georas SN
Is Tissue the Issue When It Comes to Severe Asthma?; Chest; Vol 167(4), pp. 911-913. 2025 Apr.
1. Dorscheid D
2. Gauvreau GM
3. Georas SN
4. Hiemstra PS
5. Varricchi G
6. Lambrecht BN
7. Marone G
Airway epithelial cells as drivers of severe asthma pathogenesis.; Mucosal immunology. 2025 Mar 26.
1. Gyawali B
2. Georas SN
3. Khurana S
Biologics in severe asthma: a state-of-the-art review.; European respiratory review : an official journal of the European Respiratory Society; Vol 34(175). 2025 Jan 08.
1. Donohue P
2. Connolly M
3. D'Alfonso M
4. Jackson G
5. Grasso LC
6. Cai X
7. O'Connell Ferster AP
8. Schneider GT
9. Khurana S
10. Georas SN
Peripheral Airways Dysfunction Measured by Oscillometry Differentiates Asthma from Inducible Laryngeal Obstruction.; Respiratory medicine. 2024 Dec 02.
1. Khurana S
2. Georas SN
Stepping down biologics in asthma: is it time to challenge the status quo?; The European respiratory journal; Vol 64(2). 2024 Aug 22.
1. Rimmer C
2. Hetelekides S
3. Eliseeva SI
4. Georas SN
5. Veazey JM
Correction: Budesonide promotes airway epithelial barrier integrity following double-stranded RNA challenge.; PloS one; Vol 19(7), pp. e0306666. 2024 Jul 01.
1. Canaday FT
2. Georas SN
3. Croft DP
Examining the impact of air pollution, climate change, and social determinants of health on asthma and environmental justice.; Current opinion in pulmonary medicine. 2024 Feb 27.
1. Georas SN
2. Khurana S
Update on Asthma Biology.; The Journal of allergy and clinical immunology. 2024 Feb 08.
1. Baugh A
2. Adegunsoye A
3. Connolly M
4. Croft D
5. Pew K
6. McCormack MC
7. Georas SN
Response.; Chest; Vol 165(2), pp. e62-e63. 2024 Feb.
1. Baugh A
2. Adegunsoye A
3. Connolly M
4. Croft D
5. Pew K
6. McCormack MC
7. Georas SN
Towards a Race-Neutral System of Pulmonary Function Test Results Interpretation.; Chest. 2023 Jun 17.
1. Connolly MJ
2. Donohue PA
3. Palli R
4. Khurana S
5. Cai X
6. Georas SN
Diagnostic Impact of a Race-Composite Pulmonary Function Test Results Interpretation Strategy.; Chest. 2023 Jun 17.
1. Beck LA
2. Pesonen M
3. Thakar J
4. Georas SN
5. Järvinen KM
IgE Sensitization Drives the Atopic March.; American journal of respiratory and critical care medicine. 2022 Jan 08.
1. Donohue P
2. Love NC
3. Connolly M
4. Khurana S
5. Georas SN
The effects of a deep breathing maneuver on standard airwave oscillometry measurements.; Respiratory medicine and research; Vol 83, pp. 100985. 2022 Jan 06.
1. Veazey JM
2. Wong GS
3. Eliseeva SI
4. Smyth TR
5. Chapman TJ
6. Lim K
7. Kim M
8. Georas SN
Protein kinase D3 promotes neutrophil migration during viral infection.; Immunology and cell biology. 2022 Jan 01.
1. O'Dell CT
2. Boule LA
3. Robert J
4. Georas SN
5. Eliseeva S
6. Lawrence BP
Exposure to a mixture of 23 chemicals associated with unconventional oil and gas operations alters immune response to challenge in adult mice.; Journal of immunotoxicology; Vol 18(1). 2021 Dec.
1. Georas SN
2. Wright RJ
3. Ivanova A
4. Israel E
5. LaVange LM
6. Akuthota P
7. Carr TF
8. Denlinger LC
9. Fajt ML
10. Kumar R
11. O'Neal WK
12. Phipatanakul W
13. Szefler SJ
14. Aronica MA
15. Bacharier LB
16. Burbank AJ
17. Castro M
18. Alexander LC
19. Bamdad J
20. Cardet JC
21. Comhair SAA
22. Covar RA
23. DiMango EA
24. Erwin K
25. Erzurum SC
26. Fahy JV
27. Gaffin JM
28. Gaston B
29. Gerald LB
30. Hoffman EA
31. Holguin F
32. Jackson DJ
33. James J
34. Jarjour NN
35. Kenyon NJ
36. Khatri S
37. Kirwan JP
38. Kraft M
39. Krishnan JA
40. Liu AH
41. Liu MC
42. Marquis MA
43. Martinez F
44. Mey J
45. Moore WC
46. Moy JN
47. Ortega VE
48. Peden DB
49. Pennington E
50. Peters MC
51. Ross K
52. Sanchez M
53. Smith LJ
54. Sorkness RL
55. Wechsler ME
56. Wenzel SE
57. White SR
58. Zein J
59. Zeki AA
60. Noel P
The Precision Interventions for Severe and/or Exacerbation-Prone (PrecISE) Asthma Network: an overview of Network organization, procedures and interventions.; The Journal of allergy and clinical immunology. 2021 Nov 27.
1. Georas SN
Inhaled Adjuvants and Eosinophilic Airway Inflammation in Asthma: Is a Little Bit of Lipopolysaccharide the Key to Allergen Sensitization?; Journal of immunology (Baltimore, Md. : 1950); Vol 207(7). 2021 Oct 01.
1. Georas SN
2. Donohue P
3. Connolly M
4. Wechsler ME
JAK inhibitors for asthma.; The Journal of allergy and clinical immunology; Vol 148(4). 2021 Oct.
1. Croft DP
2. Burton DS
3. Nagel DJ
4. Bhattacharya S
5. Falsey AR
6. Georas SN
7. Hopke PK
8. Johnston CJ
9. Kottmann RM
10. Litonjua AA
11. Mariani TJ
12. Rich DQ
13. Thevenet-Morrison K
14. Thurston SW
15. Utell MJ
16. McCall MN
The effect of air pollution on the transcriptomics of the immune response to respiratory infection.; Scientific reports; Vol 11(1). 2021 Sep 30.
1. Abbas F
2. Georas S
3. Cai X
4. Khurana S
Asthma Biologics: Real-World Effectiveness, Impact of Switching Biologics and Predictors of Response.; Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 2021 Sep 02.
1. Smyth T
2. Georas SN
Effects of ozone and particulate matter on airway epithelial barrier structure and function: a review of in vitro and in vivo studies.; Inhalation toxicology. 2021 Aug 04.
1. Georas SN
LPA and Autotaxin: Potential Drug Targets in Asthma?; Cell biochemistry and biophysics. 2021 Jul 31.
1. Israel E
2. Denlinger LC
3. Bacharier LB
4. LaVange LM
5. Moore WC
6. Peters MC
7. Georas SN
8. Wright RJ
9. Mauger DT
10. Noel P
11. Akuthota P
12. Bach J
13. Bleecker ER
14. Cardet JC
15. Carr TF
16. Castro M
17. Cinelli A
18. Comhair SAA
19. Covar RA
20. Alexander LC
21. DiMango EA
22. Erzurum SC
23. Fahy JV
24. Fajt ML
25. Gaston BM
26. Hoffman EA
27. Holguin F
28. Jackson DJ
29. Jain S
30. Jarjour NN
31. Ji Y
32. Kenyon NJ
33. Kosorok MR
34. Kraft M
35. Krishnan JA
36. Kumar R
37. Liu AH
38. Liu MC
39. Ly NP
40. Marquis MA
41. Martinez FD
42. Moy JN
43. O'Neal WK
44. Ortega VE
45. Peden DB
46. Phipatanakul W
47. Ross K
48. Smith LJ
49. Szefler SJ
50. Teague WG
51. Tulchinsky AF
52. Vijayanand P
53. Wechsler ME
54. Wenzel SE
55. White SR
56. Zeki AA
57. Ivanova A
PrecISE: Precision Medicine in Severe Asthma An Adaptive Platform Trial with Biomarker Ascertainment.; The Journal of allergy and clinical immunology. 2021 Mar 02.
1. Eliseeva SI
2. Knowlden ZA
3. Lester GM
4. Dean DA
5. Georas SN
6. Chapman TJ
Changes in lung immune cell infiltrates after electric field treatment in mice.; Scientific reports; Vol 11(1). 2021 Jan 14.
1. Zhang P
2. Lopez R
3. Attaway AH
4. Georas SN
5. Khatri SB
6. Abi-Saleh S
7. Zein JG
Diabetes Mellitus is Associated with Worse Outcome in Patients Hospitalized for Asthma.; The journal of allergy and clinical immunology. In practice. 2020 Nov 09.
1. Pariser DN
2. Hilt ZT
3. Ture SK
4. Blick-Nitko SK
5. Looney MR
6. Cleary SJ
7. Roman-Pagan E
8. Saunders Ii J
9. Georas SN
10. Veazey JM
11. Madere F
12. Tesoro Santos L
13. Arne AM
14. Huynh NP
15. Livada AC
16. Guerrero-Martin SM
17. Lyons CE
18. Metcalf Pate KA
19. McGrath KE
20. Palis J
21. Morrell C
Lung megakaryocytes are immune modulatory cells.; The Journal of clinical investigation. 2020 Oct 20.
1. Smyth T
2. Veazey J
3. Eliseeva S
4. Chalupa D
5. Elder A
6. Georas SN
Diesel exhaust particle exposure reduces expression of the epithelial tight junction protein Tricellulin.; Particle and fibre toxicology; Vol 17(1). 2020 Oct 15.
1. Ivanova A
2. Israel E
3. LaVange LM
4. Peters MC
5. Denlinger LC
6. Moore WC
7. Bacharier LB
8. Marquis MA
9. Gotman NM
10. Kosorok MR
11. Tomlinson C
12. Mauger DT
13. Georas SN
14. Wright RJ
15. Noel P
16. Rosner GL
17. Akuthota P
18. Billheimer D
19. Bleecker ER
20. Cardet JC
21. Castro M
22. DiMango EA
23. Erzurum SC
24. Fahy JV
25. Fajt ML
26. Gaston BM
27. Holguin F
28. Jain S
29. Kenyon NJ
30. Krishnan JA
31. Kraft M
32. Kumar R
33. Liu MC
34. Ly NP
35. Moy JN
36. Phipatanakul W
37. Ross K
38. Smith LJ
39. Szefler SJ
40. Teague WG
41. Wechsler ME
42. Wenzel SE
43. White SR
The precision interventions for severe and/or exacerbation-prone asthma (PrecISE) adaptive platform trial: statistical considerations.; Journal of biopharmaceutical statistics. 2020 Sep 17.
1. Baah S
2. Georas SN
Treatment for Pneumothorax.; The New England journal of medicine; Vol 382(18). 2020 Apr 30.
1. Clark HL
2. Valencia HE
3. Findeis-Hosey JJ
4. Georas SN
Invasive pulmonary aspergillosis in a patient with cirrhosis.; IDCases; Vol 19. 2020.
1. Veazey JM
2. Eliseeva SI
3. Hillman SE
4. Stiles K
5. Smyth TR
6. Morrissey CE
7. Tillotson EJ
8. Topham DJ
9. Chapman TJ
10. Georas SN
Inhibiting Protein Kinase D Promotes Airway Epithelial Barrier Integrity in Mouse Models of Influenza A Virus Infection.; Frontiers in immunology; Vol 11. 2020.
1. Georas SN
Targeting histone deacetylases to restore epithelial barrier integrity: A new option for personalized medicine in patients with allergic airway disorders?; The Journal of allergy and clinical immunology. 2019 Sep 23.
1. Wu EK
2. Eliseeva S
3. Rahimi H
4. Schwarz EM
5. Georas SN
Restrictive lung disease in TNF-transgenic mice: correlation of pulmonary function testing and micro-CT imaging.; Experimental lung research. 2019 Jul 18.
1. Veazey JM
2. Chapman TJ
3. Smyth TR
4. Hillman SE
5. Eliseeva SI
6. Georas SN
Distinct roles for MDA5 and TLR3 in the acute response to inhaled double-stranded RNA.; PloS one; Vol 14(5). 2019.
1. Georas S
2. Ransom N
3. Hillman S
4. Eliseeva S
5. Veazey J
6. Smyth T
7. Le K
8. Meddings J
The leaky lung test: A pilot study using inhaled mannitol to measure airway barrier function in asthma.; The Journal of asthma : official journal of the Association for the Care of Asthma. 2018 Nov 16.
1. Boulé LA
2. Chapman TJ
3. Hillman SE
4. Kassotis CD
5. O'Dell C
6. Robert J
7. Georas SN
8. Nagel SC
9. Lawrence BP
Developmental Exposure to a Mixture of 23 Chemicals Associated With Unconventional Oil and Gas Operations Alters the Immune System of Mice.; Toxicological sciences : an official journal of the Society of Toxicology. 2018 May 01.
1. Georas SN
All plugged up - noninvasive mucus score to assess airway dysfunction in asthma.; The Journal of clinical investigation; Vol 128(3). 2018 Mar 01.
1. Roto D
2. Malnoske ML
3. Winters S
4. Georas SN
A Fatal Case of Influenza B Myocarditis with Cardiac Tamponade.; Case reports in critical care; Vol 2018. 2018.
1. Long X
2. Daya M
3. Zhao J
4. Rafaels N
5. Liang H
6. Potee J
7. Campbell M
8. Zhang B
9. Araujo MI
10. Oliveira RR
11. Mathias RA
12. Gao L
13. Ruczinski I
14. Georas SN
15. Vercelli D
16. Beaty TH
17. Barnes KC
18. Chen X
19. Chen Q
The role of ST2 and ST2 genetic variants in schistosomiasis.; The Journal of allergy and clinical immunology; Vol 140(5). 2017 Nov.
1. Li N
2. Georas S
3. Alexis N
4. Fritz P
5. Xia T
6. Williams MA
7. Horner E
8. Nel A
A work group report on ultrafine particles (American Academy of Allergy, Asthma & Immunology): Why ambient ultrafine and engineered nanoparticles should receive special attention for possible adverse health outcomes in human subjects.; The Journal of allergy and clinical immunology; Vol 138(2). 2016 Aug.
1. Georas SN
2. Chapman TJ
3. Crouser ED
Sarcoidosis and T-Helper Cells. Th1, Th17, or Th17.1?; American journal of respiratory and critical care medicine; Vol 193(11). 2016 Jun 01.
1. Knowlden SA
2. Hillman SE
3. Chapman TJ
4. Patil R
5. Miller DD
6. Tigyi G
7. Georas SN
Novel Inhibitory Effect of a Lysophosphatidic Acid 2 Agonist on Allergen-Driven Airway Inflammation.; American journal of respiratory cell and molecular biology; Vol 54(3). 2016 Mar.
1. Becerra AZ
2. Georas S
3. Brenna JT
4. Hopke PK
5. Kane C
6. Chalupa D
7. Frampton MW
8. Block R
9. Rich DQ
Increases in ambient particulate matter air pollution, acute changes in platelet function, and effect modification by aspirin and omega-3 fatty acids: A panel study.; Journal of toxicology and environmental health. Part A; Vol 79(6). 2016.
1. Levy BD
2. Noel PJ
3. Freemer MM
4. Cloutier MM
5. Georas SN
6. Jarjour NN
7. Ober C
8. Woodruff PG
9. Barnes KC
10. Bender BG
11. Camargo CA
12. Chupp GL
13. Denlinger LC
14. Fahy JV
15. Fitzpatrick AM
16. Fuhlbrigge A
17. Gaston BM
18. Hartert TV
19. Kolls JK
20. Lynch SV
21. Moore WC
22. Morgan WJ
23. Nadeau KC
24. Ownby DR
25. Solway J
26. Szefler SJ
27. Wenzel SE
28. Wright RJ
29. Smith RA
30. Erzurum SC
Future Research Directions in Asthma. An NHLBI Working Group Report.; American journal of respiratory and critical care medicine; Vol 192(11). 2015 Dec 1.
1. Georas SN
2. van Wijngaarden E
3. Rich DQ
Air pollution and asthma incidence: doubt no more?; The Lancet. Respiratory medicine; Vol 3(12). 2015 Dec.
1. Block RC
2. Abdolahi A
3. Tu X
4. Georas SN
5. Brenna JT
6. Phipps RP
7. Lawrence P
8. Mousa SA
The effects of aspirin on platelet function and lysophosphatidic acids depend on plasma concentrations of EPA and DHA.; Prostaglandins, leukotrienes, and essential fatty acids; Vol 96. 2015 May.
1. Long X
2. Chen Q
3. Zhao J
4. Rafaels N
5. Mathias P
6. Liang H
7. Potee J
8. Campbell M
9. Zhang B
10. Gao L
11. Georas SN
12. Vercelli D
13. Beaty TH
14. Ruczinski I
15. Mathias R
16. Barnes KC
17. Chen X
An IL-13 promoter polymorphism associated with liver fibrosis in patients with Schistosoma japonicum.; PloS one; Vol 10(8). 2015.