URMC / Labs / Ovitt Lab / Publications Recent Publications Malcolm DWVarghese JJSorrells JEOvitt CEBenoit DSW (2017 Dec 12). The Effects of Biological Fluids on Colloidal Stability and siRNA Delivery of a pH-Responsive Micellar Nanoparticle Delivery System. ACS nano. Shubin ADFelong TJSchutrum BEJoe DSOvitt CEBenoit DS (2016 Dec 27). Encapsulation of primary salivary gland cells in enzymatically degradable poly(ethylene glycol) hydrogels promotes acinar cell characteristics. Acta biomaterialia. Weng PLVinjamuri MOvitt CE (2016 Dec 02). Ascl3 transcription factor marks a distinct progenitor lineage for non-neuronal support cells in the olfactory epithelium. Scientific reports. Maruyama EOAure MHXie XMyal YGan LOvitt CE (2016). Cell-Specific Cre Strains For Genetic Manipulation in Salivary Glands. PloS one. Aure MHArany SOvitt CE (2015 Nov). Salivary Glands: Stem Cells, Self-duplication, or Both? Journal of dental research. Shubin ADFelong TJGraunke DOvitt CEBenoit DS (2015 Jun). Development of poly(ethylene glycol) hydrogels for salivary gland tissue engineering applications. Tissue engineering. Part A. Aure MHKonieczny SFOvitt CE (2015 Apr 20). Salivary gland homeostasis is maintained through acinar cell self-duplication. Developmental cell. Arany SBenoit DSDewhurst SOvitt CE (2013 Jun). Nanoparticle-mediated gene silencing confers radioprotection to salivary glands in vivo. Molecular therapy : the journal of the American Society of Gene Therapy. Arany SXu QHernady EBenoit DSDewhurst SOvitt CE (2012 Jun). Pro-apoptotic gene knockdown mediated by nanocomplexed siRNA reduces radiation damage in primary salivary gland cultures. Journal of cellular biochemistry. Rugel-Stahl AElliott MEOvitt CE (2012 May). Ascl3 marks adult progenitor cells of the mouse salivary gland. Stem cell research. Arany SCatalán MARoztocil EOvitt CE (2011 May 15). Ascl3 knockout and cell ablation models reveal complexity of salivary gland maintenance and regeneration. Developmental biology. Lan YLiu HOvitt CEJiang R (2011 May). Generation of Osr1 conditional mutant mice. Genesis (New York, N.Y. : 2000). Liu WWatson SSLan YKeene DROvitt CELiu HSchweitzer RJiang R (2010 Oct). The atypical homeodomain transcription factor Mohawk controls tendon morphogenesis. Molecular and cellular biology. Gao YLan YOvitt CEJiang R (2009 Apr 15). Functional equivalence of the zinc finger transcription factors Osr1 and Osr2 in mouse development. Developmental biology. Bullard TKoek LRoztocil EKingsley PDMirels LOvitt CE (2008 Aug 1). Ascl3 expression marks a progenitor population of both acinar and ductal cells in mouse salivary glands. Developmental biology. Lan YWang QOvitt CEJiang R (2007 Oct). A unique mouse strain expressing Cre recombinase for tissue-specific analysis of gene function in palate and kidney development. Genesis (New York, N.Y. : 2000). Chen JBush JOOvitt CELan YJiang R (2007 Aug). The TGF-beta pseudoreceptor gene Bambi is dispensable for mouse embryonic development and postnatal survival. Genesis (New York, N.Y. : 2000). Nakamoto TSrivastava ARomanenko VGOvitt CEPerez-Cornejo PArreola JBegenisich TMelvin JE (2007 Jun). Functional and molecular characterization of the fluid secretion mechanism in human parotid acinar cells. American journal of physiology. Regulatory, integrative and comparative physiology. Begenisich TNakamoto TOvitt CENehrke KBrugnara CAlper SLMelvin JE (2004 Nov 12). Physiological roles of the intermediate conductance, Ca2+-activated potassium channel Kcnn4. The Journal of biological chemistry. Lan YOvitt CECho ESMaltby KMWang QJiang R (2004 Jul). Odd-skipped related 2 (Osr2) encodes a key intrinsic regulator of secondary palate growth and morphogenesis. Development (Cambridge, England). Schmidt DOvitt CEAnlag KFehsenfeld SGredsted LTreier ACTreier M (2004 Feb). The murine winged-helix transcription factor Foxl2 is required for granulosa cell differentiation and ovary maintenance. Development (Cambridge, England). Ronfani LFerraguti MCroci LOvitt CESchöler HRConsalez GGBianchi ME (2001 Apr). Reduced fertility and spermatogenesis defects in mice lacking chromosomal protein Hmgb2. Development (Cambridge, England). De Felice MOvitt CBiffali ERodriguez-Mallon AArra CAnastassiadis KMacchia PEMattei MGMariano ASchöler HMacchia VDi Lauro R (1998 Aug). A mouse model for hereditary thyroid dysgenesis and cleft palate. Nature genetics. Brehm AOvitt CESchöler HR (1998 Jan). Oct-4: more than just a POUerful marker of the mammalian germline? APMIS : acta pathologica, microbiologica, et immunologica Scandinavica. Bertocchini FOvitt CEConti ABarone VSchöler HRBottinelli RReggiani CSorrentino V (1997 Dec 1). Requirement for the ryanodine receptor type 3 for efficient contraction in neonatal skeletal muscles. The EMBO journal. Yeom YIFuhrmann GOvitt CEBrehm AOhbo KGross MHübner KSchöler HR (1996 Mar). Germline regulatory element of Oct-4 specific for the totipotent cycle of embryonal cells. Development (Cambridge, England). Ludwig TMunier-Lehmann HBauer UHollinshead MOvitt CLobel PHoflack B (1994 Aug 1). Differential sorting of lysosomal enzymes in mannose 6-phosphate receptor-deficient fibroblasts. The EMBO journal. Ludwig TOvitt CEBauer UHollinshead MRemmler JLobel PRüther UHoflack B (1993 Dec 15). Targeted disruption of the mouse cation-dependent mannose 6-phosphate receptor results in partial missorting of multiple lysosomal enzymes. The EMBO journal. Wang ZQOvitt CGrigoriadis AEMöhle-Steinlein URüther UWagner EF (1992 Jan). Bone and haematopoietic defects in mice lacking c-fos. Nature. Seetharam SOvitt CStrauss AWRubin DAlpers DH (1987 May 29). Fat feeding stimulates only one of the two mRNAs encoding rat intestinal membranous and secreted alkaline phosphatase. Biochemical and biophysical research communications. Ovitt CEStrauss AWAlpers DHChou JYBoime I (1986 Jun). Expression of different-sized placental alkaline phosphatase mRNAs in placenta and choriocarcinoma cells. Proceedings of the National Academy of Sciences of the United States of America. Policastro POvitt CEHoshina MFukuoka HBoothby MRBoime I (1983 Oct 10). The beta subunit of human chorionic gonadotropin is encoded by multiple genes. The Journal of biological chemistry. Ordahl CPKioussis DTilghman SMOvitt CEFornwald J (1980 Aug). Molecular cloning of developmentally regulated, low-abundance mRNA sequences from embryonic muscle. Proceedings of the National Academy of Sciences of the United States of America.