Recent Publications

• 1. Mereness JA
  2. Piraino L
  3. Chen CY
  4. Moyston T
  5. Song Y
  6. Shubin A
  7. DeLouise LA
  8. Ovitt CE
  9. Benoit DSW
  Slow hydrogel matrix degradation enhances salivary gland mimetic phenotype.; Acta biomaterialia. 2023 May 05.
• 1. Song Y
  2. Uchida H
  3. Sharipol A
  4. Piraino L
  5. Mereness JA
  6. Ingalls MH
  7. Rebhahn J
  8. Newlands SD
  9. DeLouise LA
  10. Ovitt CE
  11. Benoit DSW
  Author Correction: Development of a functional salivary gland tissue chip with potential for high-content drug screening.; Communications biology; Vol 5(1). 2022 Mar 30.
• 1. Uchida H
  2. Ingalls MH
  3. Maruyama EO
  4. Johnston CJ
  5. Hernady E
  6. Faustoferri RC
  7. Ovitt CE
  Short-term and bystander effects of radiation on murine submandibular glands.; Disease models & mechanisms. 2022 Jan 20.
• 1. Song Y
  2. Sharipol A
  3. Uchida H
  4. Ingalls MH
  5. Piraino L
  6. Mereness JA
  7. Moyston T
  8. DeLouise LA
  9. Ovitt CE
  10. Benoit DSW
  Encapsulation of Primary Salivary Gland Acinar Cell Clusters and Intercalated Ducts (AIDUCs) within Matrix Metalloproteinase (MMP)-Degradable Hydrogels to Maintain Tissue Structure and Function.; Advanced healthcare materials. 2022 Jan 06.
• 1. Uchida H
  2. Ovitt CE
  Novel impacts of saliva with regard to oral health.; The Journal of prosthetic dentistry. 2021 Jun 14.
• 1. Song Y
  2. Uchida H
  3. Sharipol A
  4. Piraino L
  5. Mereness JA
  6. Ingalls MH
  7. Rebhahn J
  8. Newlands SD
  9. DeLouise LA
  10. Ovitt CE
  11. Benoit DSW
  Author Correction: Development of a functional salivary gland tissue chip with potential for high-content drug screening.; Communications biology; Vol 4(1). 2021 Apr 30.
• 1. Song Y
  2. Uchida H
  3. Sharipol A
  4. Piraino L
  5. Mereness JA
  6. Ingalls MH
  7. Rebhahn J
  8. Newlands SD
  9. DeLouise LA
  10. Ovitt CE
  11. Benoit DSW
  Development of a functional salivary gland tissue chip with potential for high-content drug screening.; Communications biology; Vol 4(1). 2021 Mar 19.
• 1. Luitje ME
  2. Israel AK
  3. Cummings MA
  4. Giampoli EJ
  5. Allen PD
  6. Newlands SD
  7. Ovitt CE
  Long-term maintenance of acinar cells in human submandibular glands after radiation therapy.; International journal of radiation oncology, biology, physics. 2020 Nov 09.
• 1. Shubin AD
  2. Sharipol A
  3. Felong TJ
  4. Weng PL
  5. Schutrum BE
  6. Joe DS
  7. Aure MH
  8. Benoit DSW
  9. Ovitt CE
  Stress or injury induces cellular plasticity in salivary gland acinar cells.; Cell and tissue research. 2020 Jan 04.
• 1. Weng PL
  2. Luitje ME
  3. Ovitt CE
  Cellular Plasticity in Salivary Gland Regeneration.; Oral diseases. 2019 Sep 27.
• 1. Ingalls MH
  2. Hollomon AJ
  3. Newlands SD
  4. McDavid AN
  5. Ovitt CE
  Intrinsic Mitotic Activity Supports the Human Salivary Gland Acinar Cell Population.; FEBS letters. 2019 Sep 20.
• 1. Weng PL
  2. Aure MH
  3. Ovitt CE
  Concise Review: A critical evaluation of criteria used to define salivary gland stem cells.; Stem cells (Dayton, Ohio). 2019 Jun 07.
• 1. Varghese JJ
  2. Hansen ME
  3. Sharipol A
  4. Ingalls MH
  5. Ormanoski MA
  6. Newlands SD
  7. Ovitt CE
  8. Benoit DSW
  Salivary gland cell aggregates are derived from self-organization of acinar lineage cells.; Archives of oral biology; Vol 97. 2018 Oct 22.
• 1. Weng PL
  2. Aure MH
  3. Maruyama T
  4. Ovitt CE
  Limited Regeneration of Adult Salivary Glands after Severe Injury Involves Cellular Plasticity.; Cell reports; Vol 24(6). 2018 Aug 07.
• 1. Varghese JJ
  2. Schmale IL
  3. Hansen ME
  4. Newlands SD
  5. Benoit DSW
  6. Ovitt CE
  Murine Salivary Functional Assessment via Pilocarpine Stimulation Following Fractionated Radiation.; Journal of visualized experiments : JoVE. 2018 May 04.
• 1. Varghese JJ
  2. Schmale IL
  3. Wang Y
  4. Hansen ME
  5. Newlands SD
  6. Ovitt CE
  7. Benoit DSW
  Retroductal Nanoparticle Injection to the Murine Submandibular Gland.; Journal of visualized experiments : JoVE. 2018 May 03.
• 1. Varghese JJ
  2. Schmale IL
  3. Mickelson D
  4. Hansen ME
  5. Newlands SD
  6. Benoit DSW
  7. Korshunov VA
  8. Ovitt CE
  Localized Delivery of Amifostine Enhances Salivary Gland Radioprotection.; Journal of dental research. 2018 Apr 01.
• 1. Gao X
  2. Oei MS
  3. Ovitt CE
  4. Sincan M
  5. Melvin JE
  Transcriptional profiling reveals gland-specific differential expression in the three major salivary glands of the adult mouse.; Physiological genomics; Vol 50(4). 2018 Apr 01.
• 1. Malcolm DW
  2. Varghese JJ
  3. Sorrells JE
  4. Ovitt CE
  5. Benoit DSW
  The Effects of Biological Fluids on Colloidal Stability and siRNA Delivery of a pH-Responsive Micellar Nanoparticle Delivery System.; ACS nano. 2017 Dec 12.
• 1. Shubin AD
  2. Felong TJ
  3. Schutrum BE
  4. Joe DS
  5. Ovitt CE
  6. Benoit DS
  Encapsulation of primary salivary gland cells in enzymatically degradable poly(ethylene glycol) hydrogels promotes acinar cell characteristics.; Acta biomaterialia. 2016 Dec 27.
• 1. Weng PL
  2. Vinjamuri M
  3. Ovitt CE
  Ascl3 transcription factor marks a distinct progenitor lineage for non-neuronal support cells in the olfactory epithelium.; Scientific reports; Vol 6. 2016 Dec 02.
• 1. Maruyama EO
  2. Aure MH
  3. Xie X
  4. Myal Y
  5. Gan L
  6. Ovitt CE
  Cell-Specific Cre Strains For Genetic Manipulation in Salivary Glands.; PloS one; Vol 11(1). 2016.
• 1. Aure MH
  2. Arany S
  3. Ovitt CE
  Salivary Glands: Stem Cells, Self-duplication, or Both?; Journal of dental research; Vol 94(11). 2015 Nov.
• 1. Shubin AD
  2. Felong TJ
  3. Graunke D
  4. Ovitt CE
  5. Benoit DS
  Development of poly(ethylene glycol) hydrogels for salivary gland tissue engineering applications.; Tissue engineering. Part A; Vol 21(11-12). 2015 Jun.
• 1. Aure MH
  2. Konieczny SF
  3. Ovitt CE
  Salivary gland homeostasis is maintained through acinar cell self-duplication.; Developmental cell; Vol 33(2). 2015 Apr 20.
• 1. Arany S
  2. Benoit DS
  3. Dewhurst S
  4. Ovitt CE
  Nanoparticle-mediated gene silencing confers radioprotection to salivary glands in vivo.; Molecular therapy : the journal of the American Society of Gene Therapy; Vol 21(6). 2013 Jun.
• 1. Arany S
  2. Xu Q
  3. Hernady E
  4. Benoit DS
  5. Dewhurst S
  6. Ovitt CE
  Pro-apoptotic gene knockdown mediated by nanocomplexed siRNA reduces radiation damage in primary salivary gland cultures.; Journal of cellular biochemistry; Vol 113(6). 2012 Jun.
• 1. Rugel-Stahl A
  2. Elliott ME
  3. Ovitt CE
  Ascl3 marks adult progenitor cells of the mouse salivary gland.; Stem cell research; Vol 8(3). 2012 May.
• 1. Arany S
  2. Catalán MA
  3. Roztocil E
  4. Ovitt CE
  Ascl3 knockout and cell ablation models reveal complexity of salivary gland maintenance and regeneration.; Developmental biology; Vol 353(2). 2011 May 15.
• 1. Lan Y
  2. Liu H
  3. Ovitt CE
  4. Jiang R
  Generation of Osr1 conditional mutant mice.; Genesis (New York, N.Y. : 2000); Vol 49(5). 2011 May.
• 1. Liu W
  2. Watson SS
  3. Lan Y
  4. Keene DR
  5. Ovitt CE
  6. Liu H
  7. Schweitzer R
  8. Jiang R
  The atypical homeodomain transcription factor Mohawk controls tendon morphogenesis.; Molecular and cellular biology; Vol 30(20). 2010 Oct.
• 1. Gao Y
  2. Lan Y
  3. Ovitt CE
  4. Jiang R
  Functional equivalence of the zinc finger transcription factors Osr1 and Osr2 in mouse development.; Developmental biology; Vol 328(2). 2009 Apr 15.
• 1. Bullard T
  2. Koek L
  3. Roztocil E
  4. Kingsley PD
  5. Mirels L
  6. Ovitt CE
  Ascl3 expression marks a progenitor population of both acinar and ductal cells in mouse salivary glands.; Developmental biology; Vol 320(1). 2008 Aug 1.
• 1. Lan Y
  2. Wang Q
  3. Ovitt CE
  4. Jiang R
  A unique mouse strain expressing Cre recombinase for tissue-specific analysis of gene function in palate and kidney development.; Genesis (New York, N.Y. : 2000); Vol 45(10). 2007 Oct.
• 1. Chen J
  2. Bush JO
  3. Ovitt CE
  4. Lan Y
  5. Jiang R
  The TGF-beta pseudoreceptor gene Bambi is dispensable for mouse embryonic development and postnatal survival.; Genesis (New York, N.Y. : 2000); Vol 45(8). 2007 Aug.
• 1. Nakamoto T
  2. Srivastava A
  3. Romanenko VG
  4. Ovitt CE
  5. Perez-Cornejo P
  6. Arreola J
  7. Begenisich T
  8. Melvin JE
  Functional and molecular characterization of the fluid secretion mechanism in human parotid acinar cells.; American journal of physiology. Regulatory, integrative and comparative physiology; Vol 292(6). 2007 Jun.
• 1. Begenisich T
  2. Nakamoto T
  3. Ovitt CE
  4. Nehrke K
  5. Brugnara C
  6. Alper SL
  7. Melvin JE
  Physiological roles of the intermediate conductance, Ca2+-activated potassium channel Kcnn4.; The Journal of biological chemistry; Vol 279(46). 2004 Nov 12.
• 1. Lan Y
  2. Ovitt CE
  3. Cho ES
  4. Maltby KM
  5. Wang Q
  6. Jiang R
  Odd-skipped related 2 (Osr2) encodes a key intrinsic regulator of secondary palate growth and morphogenesis.; Development (Cambridge, England); Vol 131(13). 2004 Jul.
• 1. Schmidt D
  2. Ovitt CE
  3. Anlag K
  4. Fehsenfeld S
  5. Gredsted L
  6. Treier AC
  7. Treier M
  The murine winged-helix transcription factor Foxl2 is required for granulosa cell differentiation and ovary maintenance.; Development (Cambridge, England); Vol 131(4). 2004 Feb.
• 1. Ronfani L
  2. Ferraguti M
  3. Croci L
  4. Ovitt CE
  5. Schöler HR
  6. Consalez GG
  7. Bianchi ME
  Reduced fertility and spermatogenesis defects in mice lacking chromosomal protein Hmgb2.; Development (Cambridge, England); Vol 128(8). 2001 Apr.
• 1. De Felice M
  2. Ovitt C
  3. Biffali E
  4. Rodriguez-Mallon A
  5. Arra C
  6. Anastassiadis K
  7. Macchia PE
  8. Mattei MG
  9. Mariano A
  10. Schöler H
  11. Macchia V
  12. Di Lauro R
  A mouse model for hereditary thyroid dysgenesis and cleft palate.; Nature genetics; Vol 19(4). 1998 Aug.
• 1. Brehm A
  2. Ovitt CE
  3. Schöler HR
  Oct-4: more than just a POUerful marker of the mammalian germline?; APMIS : acta pathologica, microbiologica, et immunologica Scandinavica; Vol 106(1). 1998 Jan.
• 1. Bertocchini F
  2. Ovitt CE
  3. Conti A
  4. Barone V
  5. Schöler HR
  6. Bottinelli R
  7. Reggiani C
  8. Sorrentino V
  Requirement for the ryanodine receptor type 3 for efficient contraction in neonatal skeletal muscles.; The EMBO journal; Vol 16(23). 1997 Dec 1.
• 1. Yeom YI
  2. Fuhrmann G
  3. Ovitt CE
  4. Brehm A
  5. Ohbo K
  6. Gross M
  7. Hübner K
  8. Schöler HR
  Germline regulatory element of Oct-4 specific for the totipotent cycle of embryonal cells.; Development (Cambridge, England); Vol 122(3). 1996 Mar.
• 1. Ludwig T
  2. Munier-Lehmann H
  3. Bauer U
  4. Hollinshead M
  5. Ovitt C
  6. Lobel P
  7. Hoflack B
  Differential sorting of lysosomal enzymes in mannose 6-phosphate receptor-deficient fibroblasts.; The EMBO journal; Vol 13(15). 1994 Aug 1.
• 1. Ludwig T
  2. Ovitt CE
  3. Bauer U
  4. Hollinshead M
  5. Remmler J
  6. Lobel P
  7. Rüther U
  8. Hoflack B
  Targeted disruption of the mouse cation-dependent mannose 6-phosphate receptor results in partial missorting of multiple lysosomal enzymes.; The EMBO journal; Vol 12(13). 1993 Dec 15.
• 1. Wang ZQ
  2. Ovitt C
  3. Grigoriadis AE
  4. Möhle-Steinlein U
  5. Rüther U
  6. Wagner EF
  Bone and haematopoietic defects in mice lacking c-fos.; Nature; Vol 360(6406). 1992 Jan.
• 1. Seetharam S
  2. Ovitt C
  3. Strauss AW
  4. Rubin D
  5. Alpers DH
  Fat feeding stimulates only one of the two mRNAs encoding rat intestinal membranous and secreted alkaline phosphatase.; Biochemical and biophysical research communications; Vol 145(1). 1987 May 29.
• 1. Ovitt CE
  2. Strauss AW
  3. Alpers DH
  4. Chou JY
  5. Boime I
  Expression of different-sized placental alkaline phosphatase mRNAs in placenta and choriocarcinoma cells.; Proceedings of the National Academy of Sciences of the United States of America; Vol 83(11). 1986 Jun.
• 1. Policastro P
  2. Ovitt CE
  3. Hoshina M
  4. Fukuoka H
  5. Boothby MR
  6. Boime I
  The beta subunit of human chorionic gonadotropin is encoded by multiple genes.; The Journal of biological chemistry; Vol 258(19). 1983 Oct 10.