Publications

• 1. Paquette ST
  2. Dawes RP
  3. Sundar IK
  4. Rahman I
  5. Brown EB
  6. White PM
  Chronic cigarette smoke exposure drives spiral ganglion neuron loss in mice.; Scientific reports; Vol 81. 2018 Apr 10.
• 1. Sundar IK
  2. Rashid K
  3. Gerloff J
  4. Rangel-Moreno J
  5. Li D
  6. Rahman I
  Genetic ablation of histone deacetylase 2 leads to lung cellular senescence and lymphoid follicle formation in COPD/emphysema.; FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2018 Apr 09.
• 1. Kaur G
  2. Muthumalage T
  3. Rahman I
  Mechanisms of toxicity and biomarkers of flavoring and flavor enhancing chemicals in emerging tobacco and non-tobacco products.; Toxicology letters. 2018 Feb 23.
• 1. Sundar IK
  2. Rashid K
  3. Gerloff J
  4. Li D
  5. Rahman I
  Genetic Ablation of p16(Ink4a) Does Not Protect Against Cellular Senescence in Mouse Models of COPD/Emphysema.; American journal of respiratory cell and molecular biology. 2018 Feb 15.
• 1. Eddingsaas N
  2. Pagano T
  3. Cummings C
  4. Rahman I
  5. Robinson R
  6. Hensel E
  Qualitative Analysis of E-Liquid Emissions as a Function of Flavor Additives Using Two Aerosol Capture Methods.; International journal of environmental research and public health; Vol 152. 2018 Feb 13.
• 1. Khan NA
  2. Sundar IK
  3. Rahman I
  Strain- and sex-dependent pulmonary toxicity of waterpipe smoke in mouse.; Physiological reports; Vol 63. 2018 Feb.
• 1. Javed F
  2. Kellesarian SV
  3. Abduljabbar T
  4. Abduljabbar AT
  5. Akram Z
  6. Vohra F
  7. Rahman I
  8. Romanos GE
  Influence of involuntary cigarette smoke inhalation on osseointegration: a systematic review and meta-analysis of preclinical studies.; International journal of oral and maxillofacial surgery. 2017 Dec 09.
• 1. Tang M
  2. Ji C
  3. Pallo S
  4. Rahman I
  5. Johnson GVW
  Nrf2 mediates the expression of BAG3 and autophagy cargo adaptor proteins and tau clearance in an age-dependent manner.; Neurobiology of aging; Vol 63. 2017 Dec 09.
• 1. Sundar IK
  2. Sellix MT
  3. Rahman I
  Redox regulation of circadian molecular clock in chronic airway diseases.; Free radical biology & medicine. 2017 Oct 31.
• 1. Javed F
  2. ALHarthi SS
  3. BinShabaib MS
  4. Gajendra S
  5. Romanos GE
  6. Rahman I
  Toxicological impact of waterpipe smoking and flavorings in the oral cavity and respiratory system.; Inhalation toxicology. 2017 Oct 17.
• 1. Sundar IK
  2. Rashid K
  3. Sellix MT
  4. Rahman I
  The nuclear receptor and clock gene REV-ERBα regulates cigarette smoke-induced lung inflammation.; Biochemical and biophysical research communications. 2017 Sep 30.
• 1. Rahman I
  2. De Cunto G
  3. Sundar IK
  4. Lungarella G
  Vulnerability and Genetic Susceptibility to Cigarette Smoke-Induced Emphysema in Mice.; American journal of respiratory cell and molecular biology; Vol 573. 2017 Sep.
• 1. Behrsing H
  2. Hill E
  3. Raabe H
  4. Tice R
  5. Fitzpatrick S
  6. Devlin R
  7. Pinkerton K
  8. Oberdörster G
  9. Wright C
  10. Wieczorek R
  11. Aufderheide M
  12. Steiner S
  13. Krebs T
  14. Asgharian B
  15. Corley R
  16. Oldham M
  17. Adamson J
  18. Li X
  19. Rahman I
  20. Grego S
  21. Chu PH
  22. McCullough S
  23. Curren R
  In vitro exposure systems and dosimetry assessment tools for inhaled tobacco products: Workshop proceedings, conclusions and paths forward for in vitro model use.; Alternatives to laboratory animals : ATLA; Vol 453. 2017 Jul.
• 1. Javed F
  2. Abduljabbar T
  3. Vohra F
  4. Malmstrom H
  5. Rahman I
  6. Romanos GE
  Comparison of Periodontal Parameters and Self-Perceived Oral Symptoms among Cigarette-Smokers, Individuals Vaping Electronic-Cigarettes and Never-Smokers: A Pilot Study.; Journal of periodontology. 2017 Jun 23.
• 1. Lei W
  2. Lerner C
  3. Sundar IK
  4. Rahman I
  Myofibroblast differentiation and its functional properties are inhibited by nicotine and e-cigarette via mitochondrial OXPHOS complex III.; Scientific reports; Vol 7. 2017 Mar 03.
• 1. Gerloff J
  2. Sundar IK
  3. Freter R
  4. Sekera ER
  5. Friedman AE
  6. Robinson R
  7. Pagano T
  8. Rahman I
  Inflammatory Response and Barrier Dysfunction by Different e-Cigarette Flavoring Chemicals Identified by Gas Chromatography-Mass Spectrometry in e-Liquids and e-Vapors on Human Lung Epithelial Cells and Fibroblasts.; Applied in vitro toxicology; Vol 31. 2017 Mar 01.
• 1. Arbat S
  2. Dave M
  3. Niranjane V
  4. Rahman I
  5. Arbat A
  Analyzing the clinical profile of swine flu/influenza A H1N1 infection in central India: a retrospective study.; Virusdisease; Vol 281. 2017 Mar.
• 1. Javed F
  2. Kellesarian SV
  3. Sundar IK
  4. Romanos GE
  5. Rahman I
  Recent updates on electronic cigarette aerosol and inhaled nicotine effects on periodontal and pulmonary tissues.; Oral diseases. 2017 Feb 06.
• 1. Lee H
  2. Park JR
  3. Kim WJ
  4. Sundar IK
  5. Rahman I
  6. Park SM
  7. Yang SR
  Blockade of RAGE ameliorates elastase-induced emphysema development and progression via RAGE-DAMP signaling.; FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2017 Feb 01.
• 1. Sundar IK
  2. Yin Q
  3. Baier BS
  4. Yan L
  5. Mazur W
  6. Li D
  7. Susiarjo M
  8. Rahman I
  DNA methylation profiling in peripheral lung tissues of smokers and patients with COPD.; Clinical epigenetics; Vol 9. 2017.
• 1. Muthumalage T
  2. Prinz M
  3. Ansah KO
  4. Gerloff J
  5. Sundar IK
  6. Rahman I
  Inflammatory and Oxidative Responses Induced by Exposure to Commonly Used e-Cigarette Flavoring Chemicals and Flavored e-Liquids without Nicotine.; Frontiers in physiology; Vol 8. 2017.
• 1. Valacchi G
  2. Cervellati C
  3. Evelson P
  4. Rahman I
  Redox regulation of inflammatory processes.; The international journal of biochemistry & cell biology; Vol 81Pt B. 2016 Dec.
• 1. Sundar IK
  2. Javed F
  3. Romanos GE
  4. Rahman I
  E-cigarettes and flavorings induce inflammatory and pro-senescence responses in oral epithelial cells and periodontal fibroblasts.; Oncotarget; Vol 747. 2016 Nov 22.
• 1. Sundar IK
  2. Rahman I
  Gene expression profiling of epigenetic chromatin modification enzymes and histone marks by cigarette smoke: Implications for COPD and lung cancer.; American journal of physiology. Lung cellular and molecular physiology. 2016 Oct 28.
• 1. Ahmad T
  2. Sundar IK
  3. Tormos AM
  4. Lerner CA
  5. Gerloff J
  6. Yao H
  7. Rahman I
  Shelterin TPP1 Reduction Causes Telomere Attrition and Cellular Senescence via Sirt1 Deacetylase in Chronic Obstructive Pulmonary Disease.; American journal of respiratory cell and molecular biology. 2016 Aug 25.
• 1. Lerner CA
  2. Sundar IK
  3. Rahman I
  Mitochondrial redox system, dynamics, and dysfunction in lung inflammaging and COPD.; The international journal of biochemistry & cell biology. 2016 Jul 26.
• 1. Lerner CA
  2. Rutagarama P
  3. Ahmad T
  4. Sundar IK
  5. Elder A
  6. Rahman I
  Electronic cigarette aerosols and copper nanoparticles induce mitochondrial stress and promote DNA fragmentation in lung fibroblasts.; Biochemical and biophysical research communications. 2016 Jun 22.
• 1. Pagano T
  2. DiFrancesco AG
  3. Smith SB
  4. George J
  5. Wink G
  6. Rahman I
  7. Robinson RJ
  Determination of Nicotine Content and Delivery in Disposable Electronic Cigarettes Available in the United States by Gas Chromatography-Mass Spectrometry.; Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco; Vol 185. 2016 May.
• 1. Javed F
  2. Al-Kheraif AA
  3. Rahman I
  4. Millan-Luongo LT
  5. Feng C
  6. Yunker M
  7. Malmstrom H
  8. Romanos GE
  Comparison of Clinical and Radiographic Periodontal Status Between Habitual Water-Pipe Smokers and Cigarette Smokers.; Journal of periodontology; Vol 872. 2016 Feb.
• 1. Lerner CA
  2. Lei W
  3. Sundar IK
  4. Rahman I
  Genetic Ablation of CXCR2 Protects against Cigarette Smoke-Induced Lung Inflammation and Injury.; Frontiers in pharmacology; Vol 7. 2016.
• 1. Yao H
  2. Sundar IK
  3. Huang Y
  4. Gerloff J
  5. Sellix MT
  6. Sime PJ
  7. Rahman I
  Disruption of Sirtuin 1-Mediated Control of Circadian Molecular Clock and Inflammation in Chronic Obstructive Pulmonary Disease.; American journal of respiratory cell and molecular biology; Vol 536. 2015 Dec.
• 1. Sundar IK
  2. Yao H
  3. Sellix MT
  4. Rahman I
  Circadian molecular clock in lung pathophysiology.; American journal of physiology. Lung cellular and molecular physiology; Vol 30910. 2015 Nov 15.
• 1. Sundar IK
  2. Yao H
  3. Sellix MT
  4. Rahman I
  Circadian clock-coupled lung cellular and molecular functions in chronic airway diseases.; American journal of respiratory cell and molecular biology; Vol 533. 2015 Sep.
• 1. Ahmad T
  2. Sundar IK
  3. Lerner CA
  4. Gerloff J
  5. Tormos AM
  6. Yao H
  7. Rahman I
  Impaired mitophagy leads to cigarette smoke stress-induced cellular senescence: implications for chronic obstructive pulmonary disease.; FASEB journal : official publication of the Federation of American Societies for Experimental Biology; Vol 297. 2015 Jul.
• 1. Lerner CA
  2. Sundar IK
  3. Watson RM
  4. Elder A
  5. Jones R
  6. Done D
  7. Kurtzman R
  8. Ossip DJ
  9. Robinson R
  10. McIntosh S
  11. Rahman I
  Environmental health hazards of e-cigarettes and their components: Oxidants and copper in e-cigarette aerosols.; Environmental pollution (Barking, Essex : 1987); Vol 198. 2015 Mar.
• 1. Sundar IK
  2. Ahmad T
  3. Yao H
  4. Hwang JW
  5. Gerloff J
  6. Lawrence BP
  7. Sellix MT
  8. Rahman I
  Influenza A virus-dependent remodeling of pulmonary clock function in a mouse model of COPD.; Scientific reports; Vol 4. 2015.
• 1. Lerner CA
  2. Sundar IK
  3. Yao H
  4. Gerloff J
  5. Ossip DJ
  6. McIntosh S
  7. Robinson R
  8. Rahman I
  Vapors produced by electronic cigarettes and e-juices with flavorings induce toxicity, oxidative stress, and inflammatory response in lung epithelial cells and in mouse lung.; PloS one; Vol 102. 2015.
• 1. Yao H
  2. Sundar IK
  3. Ahmad T
  4. Lerner C
  5. Gerloff J
  6. Friedman AE
  7. Phipps RP
  8. Sime PJ
  9. McBurney MW
  10. Guarente L
  11. Rahman I
  SIRT1 protects against cigarette smoke-induced lung oxidative stress via a FOXO3-dependent mechanism.; American journal of physiology. Lung cellular and molecular physiology; Vol 3069. 2014 May 1.
• 1. Sundar IK
  2. Nevid MZ
  3. Friedman AE
  4. Rahman I
  Cigarette smoke induces distinct histone modifications in lung cells: implications for the pathogenesis of COPD and lung cancer.; Journal of proteome research; Vol 132. 2014 Feb 7.
• 1. Hwang JW
  2. Sundar IK
  3. Yao H
  4. Sellix MT
  5. Rahman I
  Circadian clock function is disrupted by environmental tobacco/cigarette smoke, leading to lung inflammation and injury via a SIRT1-BMAL1 pathway.; FASEB journal : official publication of the Federation of American Societies for Experimental Biology; Vol 281. 2014 Jan.
• 1. Sundar IK
  2. Yao H
  3. Huang Y
  4. Lyda E
  5. Sime PJ
  6. Sellix MT
  7. Rahman I
  Serotonin and corticosterone rhythms in mice exposed to cigarette smoke and in patients with COPD: implication for COPD-associated neuropathogenesis.; PloS one; Vol 92. 2014.
• 1. Jo C
  2. Gundemir S
  3. Pritchard S
  4. Jin YN
  5. Rahman I
  6. Johnson GV
  Nrf2 reduces levels of phosphorylated tau protein by inducing autophagy adaptor protein NDP52.; Nature communications; Vol 5. 2014.
• 1. Gilels F
  2. Paquette ST
  3. Zhang J
  4. Rahman I
  5. White PM
  Mutation of Foxo3 causes adult onset auditory neuropathy and alters cochlear synapse architecture in mice.; The Journal of neuroscience : the official journal of the Society for Neuroscience; Vol 3347. 2013 Nov 20.
• 1. Yao H
  2. Hwang JW
  3. Sundar IK
  4. Friedman AE
  5. McBurney MW
  6. Guarente L
  7. Gu W
  8. Kinnula VL
  9. Rahman I
  SIRT1 redresses the imbalance of tissue inhibitor of matrix metalloproteinase-1 and matrix metalloproteinase-9 in the development of mouse emphysema and human COPD.; American journal of physiology. Lung cellular and molecular physiology; Vol 3059. 2013 Nov 1.
• 1. Hwang JW
  2. Yao H
  3. Caito S
  4. Sundar IK
  5. Rahman I
  Redox regulation of SIRT1 in inflammation and cellular senescence.; Free radical biology & medicine; Vol 61. 2013 Aug.
• 1. Sundar IK
  2. Yao H
  3. Rahman I
  Oxidative stress and chromatin remodeling in chronic obstructive pulmonary disease and smoking-related diseases.; Antioxidants & redox signaling; Vol 1815. 2013 May 20.
• 1. Biswas S
  2. Hwang JW
  3. Kirkham PA
  4. Rahman I
  Pharmacological and dietary antioxidant therapies for chronic obstructive pulmonary disease.; Current medicinal chemistry; Vol 2012. 2013.
• 1. Yao H
  2. Sundar IK
  3. Gorbunova V
  4. Rahman I
  P21-PARP-1 pathway is involved in cigarette smoke-induced lung DNA damage and cellular senescence.; PloS one; Vol 811. 2013.
• 1. Yao H
  2. Rahman I
  Perspectives on translational and therapeutic aspects of SIRT1 in inflammaging and senescence.; Biochemical pharmacology; Vol 8410. 2012 Nov 15.
• 1. Yao H
  2. Rahman I
  Role of histone deacetylase 2 in epigenetics and cellular senescence: implications in lung inflammaging and COPD.; American journal of physiology. Lung cellular and molecular physiology; Vol 3037. 2012 Oct 1.