Publications

• 1. Javed F
  2. Abduljabbar T
  3. Vohra F
  4. Malmstrom H
  5. Rahman I
  6. Romanos GE
  (2017 Jun 23). Comparison of Periodontal Parameters and Self-Perceived Oral Symptoms among Cigarette-Smokers, Individuals Vaping Electronic-Cigarettes and Never-Smokers: A Pilot Study. Journal of periodontology.
• 1. Lei W
  2. Lerner C
  3. Sundar IK
  4. Rahman I
  (2017 Mar 03). Myofibroblast differentiation and its functional properties are inhibited by nicotine and e-cigarette via mitochondrial OXPHOS complex III. Scientific reports.
• 1. Gerloff J
  2. Sundar IK
  3. Freter R
  4. Sekera ER
  5. Friedman AE
  6. Robinson R
  7. Pagano T
  8. Rahman I
  (2017 Mar 01). Inflammatory Response and Barrier Dysfunction by Different e-Cigarette Flavoring Chemicals Identified by Gas Chromatography-Mass Spectrometry in e-Liquids and e-Vapors on Human Lung Epithelial Cells and Fibroblasts. Applied in vitro toxicology.
• 1. Arbat S
  2. Dave M
  3. Niranjane V
  4. Rahman I
  5. Arbat A
  (2017 Mar). Analyzing the clinical profile of swine flu/influenza A H1N1 infection in central India: a retrospective study. Virusdisease.
• 1. Javed F
  2. Kellesarian SV
  3. Sundar IK
  4. Romanos GE
  5. Rahman I
  (2017 Feb 06). Recent updates on electronic cigarette aerosol and inhaled nicotine effects on periodontal and pulmonary tissues. Oral diseases.
• 1. Lee H
  2. Park JR
  3. Kim WJ
  4. Sundar IK
  5. Rahman I
  6. Park SM
  7. Yang SR
  (2017 Feb 01). Blockade of RAGE ameliorates elastase-induced emphysema development and progression via RAGE-DAMP signaling. FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
• 1. Sundar IK
  2. Yin Q
  3. Baier BS
  4. Yan L
  5. Mazur W
  6. Li D
  7. Susiarjo M
  8. Rahman I
  (2017). DNA methylation profiling in peripheral lung tissues of smokers and patients with COPD. Clinical epigenetics.
• 1. Valacchi G
  2. Cervellati C
  3. Evelson P
  4. Rahman I
  (2016 Dec). Redox regulation of inflammatory processes. The international journal of biochemistry & cell biology.
• 1. Sundar IK
  2. Javed F
  3. Romanos GE
  4. Rahman I
  (2016 Nov 22). E-cigarettes and flavorings induce inflammatory and pro-senescence responses in oral epithelial cells and periodontal fibroblasts. Oncotarget.
• 1. Sundar IK
  2. Rahman I
  (2016 Oct 28). Gene expression profiling of epigenetic chromatin modification enzymes and histone marks by cigarette smoke: Implications for COPD and lung cancer. American journal of physiology. Lung cellular and molecular physiology.
• 1. Ahmad T
  2. Sundar IK
  3. Tormos AM
  4. Lerner CA
  5. Gerloff J
  6. Yao H
  7. Rahman I
  (2016 Aug 25). Shelterin TPP1 Reduction Causes Telomere Attrition and Cellular Senescence via Sirt1 Deacetylase in Chronic Obstructive Pulmonary Disease. American journal of respiratory cell and molecular biology.
• 1. Lerner CA
  2. Sundar IK
  3. Rahman I
  (2016 Jul 26). Mitochondrial redox system, dynamics, and dysfunction in lung inflammaging and COPD. The international journal of biochemistry & cell biology.
• 1. Lerner CA
  2. Rutagarama P
  3. Ahmad T
  4. Sundar IK
  5. Elder A
  6. Rahman I
  (2016 Jun 22). Electronic cigarette aerosols and copper nanoparticles induce mitochondrial stress and promote DNA fragmentation in lung fibroblasts. Biochemical and biophysical research communications.
• 1. Pagano T
  2. DiFrancesco AG
  3. Smith SB
  4. George J
  5. Wink G
  6. Rahman I
  7. Robinson RJ
  (2016 May). Determination of Nicotine Content and Delivery in Disposable Electronic Cigarettes Available in the United States by Gas Chromatography-Mass Spectrometry. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco.
• 1. Javed F
  2. Al-Kheraif AA
  3. Rahman I
  4. Millan-Luongo LT
  5. Feng C
  6. Yunker M
  7. Malmstrom H
  8. Romanos GE
  (2016 Feb). Comparison of Clinical and Radiographic Periodontal Status Between Habitual Water-Pipe Smokers and Cigarette Smokers. Journal of periodontology.
• 1. Lerner CA
  2. Lei W
  3. Sundar IK
  4. Rahman I
  (2016). Genetic Ablation of CXCR2 Protects against Cigarette Smoke-Induced Lung Inflammation and Injury. Frontiers in pharmacology.
• 1. Yao H
  2. Sundar IK
  3. Huang Y
  4. Gerloff J
  5. Sellix MT
  6. Sime PJ
  7. Rahman I
  (2015 Dec). Disruption of Sirtuin 1-Mediated Control of Circadian Molecular Clock and Inflammation in Chronic Obstructive Pulmonary Disease. American journal of respiratory cell and molecular biology.
• 1. Sundar IK
  2. Yao H
  3. Sellix MT
  4. Rahman I
  (2015 Nov 15). Circadian molecular clock in lung pathophysiology. American journal of physiology. Lung cellular and molecular physiology.
• 1. Sundar IK
  2. Yao H
  3. Sellix MT
  4. Rahman I
  (2015 Sep). Circadian clock-coupled lung cellular and molecular functions in chronic airway diseases. American journal of respiratory cell and molecular biology.
• 1. Ahmad T
  2. Sundar IK
  3. Lerner CA
  4. Gerloff J
  5. Tormos AM
  6. Yao H
  7. Rahman I
  (2015 Jul). Impaired mitophagy leads to cigarette smoke stress-induced cellular senescence: implications for chronic obstructive pulmonary disease. FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
• 1. Lerner CA
  2. Sundar IK
  3. Watson RM
  4. Elder A
  5. Jones R
  6. Done D
  7. Kurtzman R
  8. Ossip DJ
  9. Robinson R
  10. McIntosh S
  11. Rahman I
  (2015 Mar). Environmental health hazards of e-cigarettes and their components: Oxidants and copper in e-cigarette aerosols. Environmental pollution (Barking, Essex : 1987).
• 1. Sundar IK
  2. Ahmad T
  3. Yao H
  4. Hwang JW
  5. Gerloff J
  6. Lawrence BP
  7. Sellix MT
  8. Rahman I
  (2015). Influenza A virus-dependent remodeling of pulmonary clock function in a mouse model of COPD. Scientific reports.
• 1. Lerner CA
  2. Sundar IK
  3. Yao H
  4. Gerloff J
  5. Ossip DJ
  6. McIntosh S
  7. Robinson R
  8. Rahman I
  (2015). Vapors produced by electronic cigarettes and e-juices with flavorings induce toxicity, oxidative stress, and inflammatory response in lung epithelial cells and in mouse lung. PloS one.
• 1. Yao H
  2. Sundar IK
  3. Ahmad T
  4. Lerner C
  5. Gerloff J
  6. Friedman AE
  7. Phipps RP
  8. Sime PJ
  9. McBurney MW
  10. Guarente L
  11. Rahman I
  (2014 May 1). SIRT1 protects against cigarette smoke-induced lung oxidative stress via a FOXO3-dependent mechanism. American journal of physiology. Lung cellular and molecular physiology.
• 1. Sundar IK
  2. Nevid MZ
  3. Friedman AE
  4. Rahman I
  (2014 Feb 7). Cigarette smoke induces distinct histone modifications in lung cells: implications for the pathogenesis of COPD and lung cancer. Journal of proteome research.
• 1. Hwang JW
  2. Sundar IK
  3. Yao H
  4. Sellix MT
  5. Rahman I
  (2014 Jan). Circadian clock function is disrupted by environmental tobacco/cigarette smoke, leading to lung inflammation and injury via a SIRT1-BMAL1 pathway. FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
• 1. Sundar IK
  2. Yao H
  3. Huang Y
  4. Lyda E
  5. Sime PJ
  6. Sellix MT
  7. Rahman I
  (2014). Serotonin and corticosterone rhythms in mice exposed to cigarette smoke and in patients with COPD: implication for COPD-associated neuropathogenesis. PloS one.
• 1. Jo C
  2. Gundemir S
  3. Pritchard S
  4. Jin YN
  5. Rahman I
  6. Johnson GV
  (2014). Nrf2 reduces levels of phosphorylated tau protein by inducing autophagy adaptor protein NDP52. Nature communications.
• 1. Gilels F
  2. Paquette ST
  3. Zhang J
  4. Rahman I
  5. White PM
  (2013 Nov 20). Mutation of Foxo3 causes adult onset auditory neuropathy and alters cochlear synapse architecture in mice. The Journal of neuroscience : the official journal of the Society for Neuroscience.
• 1. Yao H
  2. Hwang JW
  3. Sundar IK
  4. Friedman AE
  5. McBurney MW
  6. Guarente L
  7. Gu W
  8. Kinnula VL
  9. Rahman I
  (2013 Nov 1). SIRT1 redresses the imbalance of tissue inhibitor of matrix metalloproteinase-1 and matrix metalloproteinase-9 in the development of mouse emphysema and human COPD. American journal of physiology. Lung cellular and molecular physiology.
• 1. Hwang JW
  2. Yao H
  3. Caito S
  4. Sundar IK
  5. Rahman I
  (2013 Aug). Redox regulation of SIRT1 in inflammation and cellular senescence. Free radical biology & medicine.
• 1. Sundar IK
  2. Yao H
  3. Rahman I
  (2013 May 20). Oxidative stress and chromatin remodeling in chronic obstructive pulmonary disease and smoking-related diseases. Antioxidants & redox signaling.
• 1. Biswas S
  2. Hwang JW
  3. Kirkham PA
  4. Rahman I
  (2013). Pharmacological and dietary antioxidant therapies for chronic obstructive pulmonary disease. Current medicinal chemistry.
• 1. Yao H
  2. Sundar IK
  3. Gorbunova V
  4. Rahman I
  (2013). P21-PARP-1 pathway is involved in cigarette smoke-induced lung DNA damage and cellular senescence. PloS one.
• 1. Yao H
  2. Rahman I
  (2012 Nov 15). Perspectives on translational and therapeutic aspects of SIRT1 in inflammaging and senescence. Biochemical pharmacology.
• 1. Yao H
  2. Rahman I
  (2012 Oct 1). Role of histone deacetylase 2 in epigenetics and cellular senescence: implications in lung inflammaging and COPD. American journal of physiology. Lung cellular and molecular physiology.
• 1. Yao H
  2. Chung S
  3. Hwang JW
  4. Rajendrasozhan S
  5. Sundar IK
  6. Dean DA
  7. McBurney MW
  8. Guarente L
  9. Gu W
  10. Rönty M
  11. Kinnula VL
  12. Rahman I
  (2012 Jun). SIRT1 protects against emphysema via FOXO3-mediated reduction of premature senescence in mice. The Journal of clinical investigation.
• 1. Rahman I
  2. MacNee W
  (2012 Jun). Antioxidant pharmacological therapies for COPD. Current opinion in pharmacology.
• 1. Rahman I
  (2012 May). Pharmacological antioxidant strategies as therapeutic interventions for COPD. Biochimica et biophysica acta.
• 1. Rahman I
  2. Kinnula VL
  3. Gorbunova V
  4. Yao H
  (2012 May). SIRT1 as a therapeutic target in inflammaging of the pulmonary disease. Preventive medicine.
• 1. Rahman I
  2. Kinnula VL
  (2012 May). Strategies to decrease ongoing oxidant burden in chronic obstructive pulmonary disease. Expert review of clinical pharmacology.
• 1. Sundar IK
  2. Chung S
  3. Hwang JW
  4. Lapek JD
  5. Bulger M
  6. Friedman AE
  7. Yao H
  8. Davie JR
  9. Rahman I
  (2012). Mitogen- and stress-activated kinase 1 (MSK1) regulates cigarette smoke-induced histone modifications on NF-κB-dependent genes. PloS one.
• 1. Nadtochiy SM
  2. Yao H
  3. McBurney MW
  4. Gu W
  5. Guarente L
  6. Rahman I
  7. Brookes PS
  (2011 Oct). SIRT1-mediated acute cardioprotection. American journal of physiology. Heart and circulatory physiology.
• 1. Hwang JW
  2. Rajendrasozhan S
  3. Yao H
  4. Chung S
  5. Sundar IK
  6. Huyck HL
  7. Pryhuber GS
  8. Kinnula VL
  9. Rahman I
  (2011 Jul 15). FOXO3 deficiency leads to increased susceptibility to cigarette smoke-induced inflammation, airspace enlargement, and chronic obstructive pulmonary disease. Journal of immunology (Baltimore, Md. : 1950).
• 1. Yao H
  2. Rahman I
  (2011 Jul 15). Current concepts on oxidative/carbonyl stress, inflammation and epigenetics in pathogenesis of chronic obstructive pulmonary disease. Toxicology and applied pharmacology.
• 1. Sundar IK
  2. Mullapudi N
  3. Yao H
  4. Spivack SD
  5. Rahman I
  (2011 Jul). Lung cancer and its association with chronic obstructive pulmonary disease: update on nexus of epigenetics. Current opinion in pulmonary medicine.
• 1. Londhe VA
  2. Sundar IK
  3. Lopez B
  4. Maisonet TM
  5. Yu Y
  6. Aghai ZH
  7. Rahman I
  (2011 May). Hyperoxia impairs alveolar formation and induces senescence through decreased histone deacetylase activity and up-regulation of p21 in neonatal mouse lung. Pediatric research.
• 1. Sundar IK
  2. Hwang JW
  3. Wu S
  4. Sun J
  5. Rahman I
  (2011 Mar 4). Deletion of vitamin D receptor leads to premature emphysema/COPD by increased matrix metalloproteinases and lymphoid aggregates formation. Biochemical and biophysical research communications.
• 1. Nadtochiy SM
  2. Redman E
  3. Rahman I
  4. Brookes PS
  (2011 Feb 15). Lysine deacetylation in ischaemic preconditioning: the role of SIRT1. Cardiovascular research.
• 1. Chung S
  2. Sundar IK
  3. Hwang JW
  4. Yull FE
  5. Blackwell TS
  6. Kinnula VL
  7. Bulger M
  8. Yao H
  9. Rahman I
  (2011). NF-κB inducing kinase, NIK mediates cigarette smoke/TNFα-induced histone acetylation and inflammation through differential activation of IKKs. PloS one.