URMC / Labs / Thornton Lab / Lab Members Lab Members Principal InvestigatorCharles A. Thornton, M.D.MC 5-5207Phone: (585) 275-2542Email CharlesResearch Interest: Myotonic dystrophy, repeat expansion diseases, and therapeutic development for neuromuscular disorders.FacultyZhenzhi Tang, Ph.D.Research FacultyEmail ZhenzhiResearch Interest: Uses traditional transgenic and novel genetic engineering techniques to generate mouse models of DM. These models aid in our understanding of expanded repeat toxicity and serve as valuable tools for testing potential therapeutics.Research StaffSarah LeistmanLab TechnicianResearch Interest: Performs the majority of genotyping of the 40+ transgenic lines of mice in the Thornton lab, determines breeding strategies, and attends to colony maintenance of these lines.Linda RichardsonLaboratory ManagerResearch Interest: Oversees general day to day functioning of lab and general contact. Responsible for husbandry and colony maintenance of 40+ lines of transgenic mice used as therapeutic models of neuromuscular diseases.Ryan WisePhysician Support SpecialistPhone: (585) 275-2542Research AssistantsByron ArevaloUndergraduate StudentResearch Interest: Currently an undergraduate majoring in Neuroscience working in the lab. Byron’s lab duties consist of running electrophoresis gels, doing PCRs and assisting Dr. Tang with his projects.Julianna SavitzUndergraduate StudentResearch Interest: Currently an undergraduate majoring in Environmental Health working in the lab. Julianna works closely with technicians in the lab with DNA extraction and genotyping.