URochester Medicine / Labs / Zhang Lab / Publications

Recent Publications

1. Jiang C
2. Miao T
3. Xing X
4. Schilling KJ
5. Lenhard N
6. Wang L
7. McDowell S
8. Nilsson BL
9. Wang H
10. Zhang X
Masquelet Inspired in Vivo Engineered Extracellular Matrix as Functional Periosteum for Bone Defect Repair and Reconstruction.; Advanced healthcare materials. 2025 Jan 22.
1. Zhai Y
2. Zhou Z
3. Xing X
4. Nuzzle M
5. Zhang X
Differential bone and vessel type formation at superior and dura periosteum during cranial bone defect repair.; Bone research; Vol 13(1), pp. 8. 2025 Jan 13.
1. Ahamed SHR
2. Shakil S
3. Lyu H
4. Zhang X
5. Luo J
Doctors vs. Nurses: Understanding the Great Divide in Vaccine Hesitancy among Healthcare Workers.; Proceedings : ... IEEE International Conference on Big Data. IEEE International Conference on Big Data; Vol 2022, pp. 5865-5870. 2022 Dec.
1. Wang H
2. Zhou X
3. Wang J
4. Zhang X
5. Zhu M
6. Wang H
Fabrication of channeled scaffolds through polyelectrolyte complex (PEC) printed sacrificial templates for tissue formation.; Bioactive materials; Vol 17. 2022 Nov.
1. Parimala Chelvi Ratnamani M
2. Zhang X
3. Wang H
A Comprehensive Assessment on the Pivotal Role of Hydrogels in Scaffold-Based Bioprinting.; Gels (Basel, Switzerland); Vol 8(4). 2022 Apr 13.
1. Schilling K
2. Zhai Y
3. Zhou Z
4. Zhou B
5. Brown E
6. Zhang X
High resolution imaging of the osteogenic and angiogenic interface at the site of murine cranial bone defect repair via multiphoton microscopy.; eLife; Vol 11. 2022 Jan 03.
1. Schilling K
2. Brown E
3. Zhang X
NAD(P)H autofluorescence lifetime imaging enables single cell analyses of cellular metabolism of osteoblasts in vitro and in vivo via two-photon microscopy.; Bone. 2021 Nov 12.
1. Zhai Y
2. Schilling K
3. Wang T
4. El Khatib M
5. Vinogradov S
6. Brown EB
7. Zhang X
Spatiotemporal blood vessel specification at the osteogenesis and angiogenesis interface of biomimetic nanofiber-enabled bone tissue engineering.; Biomaterials; Vol 276. 2021 Jul 26.
1. Lam LRW
2. Schilling K
3. Romas S
4. Misra R
5. Zhou Z
6. Caton JG
7. Zhang X
Electrospun core-shell nanofibers with encapsulated enamel matrix derivative for guided periodontal tissue regeneration.; Dental materials journal. 2021 Jun 12.
1. Zhuang Z
2. John JV
3. Liao H
4. Luo J
5. Rubery P
6. Mesfin A
7. Boda SK
8. Xie J
9. Zhang X
Periosteum Mimetic Coating on Structural Bone Allografts via Electrospray Deposition Enhances Repair and Reconstruction of Segmental Defects.; ACS biomaterials science & engineering; Vol 6(11). 2020 Nov 09.
1. Schilling K
2. El Khatib M
3. Plunkett S
4. Xue J
5. Xia Y
6. Vinogradov SA
7. Brown E
8. Zhang X
Electrospun Fiber Mesh for High-Resolution Measurements of Oxygen Tension in Cranial Bone Defect Repair.; ACS applied materials & interfaces; Vol 11(37). 2019 Sep 18.
1. Yukata K
2. Xie C
3. Li TF
4. Brown ML
5. Kanchiku T
6. Zhang X
7. Awad HA
8. Schwarz EM
9. Beck CA
10. Jonason JH
11. O'Keefe RJ
Teriparatide (human PTH1-34) compensates for impaired fracture healing in COX-2 deficient mice.; Bone. 2018 Feb 02.
1. Wang T
2. Zhai Y
3. Nuzzo M
4. Yang X
5. Yang Y
6. Zhang X
Layer-by-layer nanofiber-enabled engineering of biomimetic periosteum for bone repair and reconstruction.; Biomaterials; Vol 182. 2018 Jan.
1. Zhang X
Intravital Imaging to Understand Spatiotemporal Regulation of Osteogenesis and Angiogenesis in Cranial Defect Repair and Regeneration.; Methods in molecular biology (Clifton, N.J.); Vol 1842. 2018.
1. Zhang L
2. Wang T
3. Chang M
4. Kaiser C
5. Kim JD
6. Wu T
7. Cao X
8. Zhang X
9. Schwarz EM
Teriparatide treatment improves bone defect healing via anabolic effects on new bone formation and non-anabolic effects on inhibition of mast cells in a murine cranial window model.; Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 2017 May 30.
1. Wang T
2. Zhang X
3. Bikle DD
Osteogenic Differentiation of Periosteal Cells During Fracture Healing.; Journal of cellular physiology; Vol 232(5). 2017 May.
1. Antebi B
2. Zhang L
3. Sheyn D
4. Pelled G
5. Zhang X
6. Gazit Z
7. Schwarz EM
8. Gazit D
Controlling Arteriogenesis and Mast Cells Are Central to Bioengineering Solutions for Critical Bone Defect Repair Using Allografts.; Bioengineering; Vol 3(1). 2016 Mar.
1. Antebi B
2. Zhang L
3. Sheyn D
4. Pelled G
5. Zhang X
6. Gazit Z
7. Schwarz EM
8. Gazit D
Controlling Arteriogenesis and Mast Cells Are Central to Bioengineering Solutions for Critical Bone Defect Repair Using Allografts.; Bioengineering (Basel, Switzerland); Vol 3(1). 2016 Jan 11.
1. Huang C
2. Ness VP
3. Yang X
4. Chen H
5. Luo J
6. Brown EB
7. Zhang X
Spatiotemporal Analyses of Osteogenesis and Angiogenesis via Intravital Imaging in Cranial Bone Defect Repair.; Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 2015 Jan 15.
1. Yukata K
2. Xie C
3. Li TF
4. Takahata M
5. Hoak D
6. Kondabolu S
7. Zhang X
8. Awad HA
9. Schwarz EM
10. Beck CA
11. Jonason JH
12. O'Keefe RJ
Aging periosteal progenitor cells have reduced regenerative responsiveness to bone injury and to the anabolic actions of PTH 1-34 treatment.; Bone; Vol 62. 2014 May.
1. Huang C
2. Tang M
3. Yehling E
4. Zhang X
Overexpressing sonic hedgehog peptide restores periosteal bone formation in a murine bone allograft transplantation model.; Molecular therapy : the journal of the American Society of Gene Therapy; Vol 22(2). 2014 Feb.
1. Huang C
2. Xue M
3. Chen H
4. Jiao J
5. Herschman HR
6. O'Keefe RJ
7. Zhang X
The spatiotemporal role of COX-2 in osteogenic and chondrogenic differentiation of periosteum-derived mesenchymal progenitors in fracture repair.; PloS one; Vol 9(7). 2014.
1. Hoffman MD
2. Xie C
3. Zhang X
4. Benoit DS
The effect of mesenchymal stem cells delivered via hydrogel-based tissue engineered periosteum on bone allograft healing.; Biomaterials; Vol 34(35). 2013 Nov.
1. Lyu S
2. Huang C
3. Yang H
4. Zhang X
Electrospun fibers as a scaffolding platform for bone tissue repair.; Journal of orthopaedic research : official publication of the Orthopaedic Research Society; Vol 31(9). 2013 Sep.
1. Yazici C
2. Takahata M
3. Reynolds DG
4. Xie C
5. Samulski RJ
6. Samulski J
7. Beecham EJ
8. Gertzman AA
9. Spilker M
10. Zhang X
11. O'Keefe RJ
12. Awad HA
13. Schwarz EM
Self-complementary AAV2.5-BMP2-coated femoral allografts mediated superior bone healing versus live autografts in mice with equivalent biomechanics to unfractured femur.; Molecular therapy : the journal of the American Society of Gene Therapy; Vol 19(8). 2011 Aug.
1. Wang Q
2. Huang C
3. Xue M
4. Zhang X
Expression of endogenous BMP-2 in periosteal progenitor cells is essential for bone healing.; Bone; Vol 48(3). 2011 Mar 01.
1. Wang Q
2. Huang C
3. Zeng F
4. Xue M
5. Zhang X
Activation of the Hh pathway in periosteum-derived mesenchymal stem cells induces bone formation in vivo: implication for postnatal bone repair.; The American journal of pathology; Vol 177(6). 2010 Dec.
1. Liu Y
2. Zhang X
3. Xia Y
4. Yang H
Magnetic-field-assisted electrospinning of aligned straight and wavy polymeric nanofibers.; Advanced materials (Deerfield Beach, Fla.); Vol 22(22). 2010 Jun 11.
1. Tsutsumi R
2. Xie C
3. Wei X
4. Zhang X
5. Flick LM
6. Schwarz EM
7. O'Keefe RJ
PGE2 Signaling Through the EP4 Receptor on Fibroblasts Upregulates RANKL and Stimulates Osteolysis; J Bone Miner Res; Vol 24(10), pp. 1753-62. 2009 Jan 01.
1. Tsutsumi R
2. Xie C
3. Wei X
4. Zhang M
5. Zhang X
6. Flick LM
7. Schwarz EM
8. O'Keefe RJ
PGE2 signaling through the EP4 receptor on fibroblasts upregulates RANKL and stimulates osteolysis.; Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research; Vol 24(10). 2009 Oct.
1. Xie C
2. Liang B
3. Xue M
4. Lin AS
5. Loiselle A
6. Schwarz EM
7. Guldberg RE
8. O'Keefe RJ
9. Zhang X
Rescue of impaired fracture healing in COX-2-/- mice via activation of prostaglandin E2 receptor subtype 4.; The American journal of pathology; Vol 175(2). 2009 Aug.
1. Xie C
2. Liang B
3. Xue M
4. Lin A
5. Loiselle A
6. Schwarz EM
7. Guldberg RE
8. O'Keefe RJ
9. Zhang X
Rescue of Impaired Fracture Healing in Cox-2-/- mice via Activation of Prostaglandin E2 Receptor Subtype 4; The American Journal of Pathology; Vol 175(2), pp. 772-85. 2009 Jan 01.
1. Wei X
2. Zhang X
3. Flick LM
4. Drissi H
5. Schwarz EM
6. O'Keefe RJ
Titanium particles stimulate COX-2 expression in synovial fibroblasts through an oxidative stress-induced, calpain-dependent, NF-kappaB pathway.; American journal of physiology. Cell physiology; Vol 297(2). 2009 Aug.
1. Clark CA
2. Li TF
3. Kim KO
4. Drissi H
5. Zuscik MJ
6. Zhang X
7. O'Keefe RJ
Prostaglandin E2 inhibits BMP signaling and delays chondrocyte maturation; J. Orthop. Res.; Vol 27(6), pp. 785-92. 2009 Jan 01.
1. Clark CA
2. Li TF
3. Kim KO
4. Drissi H
5. Zuscik MJ
6. Zhang X
7. O'Keefe RJ
Prostaglandin E2 inhibits BMP signaling and delays chondrocyte maturation.; Journal of orthopaedic research : official publication of the Orthopaedic Research Society; Vol 27(6). 2009 Jun.
1. Xie C
2. Kingsley P
3. Zuscik MJ
4. Schwarz EM
5. Awad H
6. Guldberg R
7. Drissi H
8. Puzas E
9. Boyce B
10. Zhang X
11. O'Keefe RJ
Reduced COX-2 expression in aged mice is associated with impaired fracture healing; Journal of Bone & Mineral Research; Vol 24(2), pp. 251-64. 2009 Jan 01.
1. Naik AA
2. Xie C
3. Zuscik MJ
4. Kingsley P
5. Schwarz EM
6. Awad H
7. Guldberg R
8. Drissi H
9. Puzas JE
10. Boyce B
11. Zhang X
12. O'Keefe RJ
Reduced COX-2 expression in aged mice is associated with impaired fracture healing.; Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research; Vol 24(2). 2009 Feb.
1. Xie C
2. Liang B
3. Xue M
4. Lin A
5. Loiselle AS
6. EM G
7. O'Keefe RJ
8. Zhang X
Rescue of impaired fracture healing in COX-2 mice via activation of prostaglandin E2 receptor subtype 4.; The American Journal of Pathology; Vol 175(2), pp. 772-85. 2009 Jan 01.
1. Xie C
2. Ming X
3. Wang Q
4. Schwarz EM
5. Guldberg RE
6. O'Keefe RJ
7. Zhang X
COX-2 from the injury milieu is critical for the initiation of periosteal progenitor cell mediated bone healing.; Bone; Vol 43(6). 2008 Dec.
1. Yazici C
2. Yanoso L
3. Xie C
4. Reynolds DG
5. Samulski RJ
6. Samulski J
7. Yannariello-Brown J
8. Gertzman AA
9. Zhang X
10. Awad HA
11. Schwarz EM
The effect of surface demineralization of cortical bone allograft on the properties of recombinant adeno-associated virus coatings.; Biomaterials; Vol 29(28). 2008 Oct.
1. Zhang X
2. Awad HA
3. O'Keefe RJ
4. Guldberg RE
5. Schwarz EM
A perspective: engineering periosteum for structural bone graft healing.; Clinical orthopaedics and related research; Vol 466(8). 2008 Aug.
1. Zuscik MJ
2. Hilton MJ
3. Zhang X
4. Chen D
5. O'Keefe RJ
Regulation of chondrogenesis and chondrocyte differentiation by stress.; The Journal of clinical investigation; Vol 118(2). 2008 Feb.
1. Xie C
2. Xue M
3. Wang Q
4. Schwarz EM
5. O'Keefe RJ
6. Zhang X
Tamoxifen-inducible CreER-mediated gene targeting in periosteum via bone-graft transplantation.; The Journal of bone and joint surgery. American volume; Vol 90 Suppl 1. 2008 Feb.
1. Zhang X
2. Awad AH
3. O'Keefe RJ
4. Guldberg RJ
5. Schwarz EM
Periosteum is essential for the initiation of structural bone graft healing: implication for tissue engineering.; Clinical Orthopaedics and Related Research.. 2008 Jan 01.
1. Zhang X
2. Awad HA
3. O'Keefe RJ
4. Guldberg RE
5. Schwarz EM
Perspective: Engineering Periosteum for Structural Bone Graft Healing; Clinical Orthopaedics & Related Research; Vol 466(8), pp. 1777-87. 2008 Jan 01.
1. Xie C
2. Xue M
3. Lin A
4. Schwarz E
5. Guldberg R
6. O'Keefe R
7. Zhang X
COX-2 from the injury milieu is critical for the initiation of periosteal progenitor cell mediated bone healing; Bone; Vol 43(6), pp. 1075-83. 2008 Jan 01.
1. Yazici C
2. Yanoso L
3. Xie C
4. Reynolds DG
5. Samulski RJ
6. Samulski J
7. Yannariello-Brown J
8. Gertzmann AA
9. Zhang X
10. Awad HA
11. Schwarz EM
The effect of surface demineralization of cortical bone allograft on the properties of recombinant adeno-associated virus coatings; Biomaterials; Vol 29(28), pp. 3882-7. 2008 Jan 01.
1. Zhang X
2. Sun B
Organic crystal fibers aligned into oriented bundles with polarized emission.; The journal of physical chemistry. B; Vol 111(37). 2007 Sep 20.
1. Awad HA
2. Zhang X
3. Reynolds DG
4. Guldberg RE
5. O'Keefe RJ
6. Schwarz EM
Recent advances in gene delivery for structural bone allografts.; Tissue engineering; Vol 13(8). 2007 Aug.
1. Wang Q
2. Wei X
3. Zhu T
4. Zhang M
5. Shen R
6. Xing L
7. O'Keefe RJ
8. Chen D
Bone morphogenetic protein 2 activates Smad6 gene transcription through bone-specific transcription factor Runx2.; The Journal of biological chemistry; Vol 282(14). 2007 Apr 6.
1. Xie C
2. Reynolds D
3. Awad H
4. Rubery PT
5. Pelled G
6. Gazit D
7. Guldberg RE
8. Schwarz EM
9. O'Keefe RJ
10. Zhang X
Structural bone allograft combined with genetically engineered mesenchymal stem cells as a novel platform for bone tissue engineering.; Tissue engineering; Vol 13(3). 2007 Mar.
1. Reynolds DG
2. Hock C
3. Shaikh S
4. Jacobson J
5. Zhang X
6. Rubery PT
7. Beck CA
8. O'keefe RJ
9. Lerner AL
10. Schwarz EM
11. Awad HA
Micro-computed tomography prediction of biomechanical strength in murine structural bone grafts.; Journal of biomechanics; Vol 40(14). 2007.
1. Zhang X
2. Chen D
Targeted Gene Delivery for Femoral Allografts: A Novel Acellular Tissue Engineering Approach; Genesis; Vol 45(1), pp. 44-50. 2007 Jan 01.
1. Chen M
2. Lichtler AC
3. Sheu TJ
4. Xie C
5. Zhang X
6. O'Keefe RJ
7. Chen D
Generation of a transgenic mouse model with chondrocyte-specific and tamoxifen-inducible expression of Cre recombinase.; Genesis (New York, N.Y. : 2000); Vol 45(1). 2007 Jan.
1. Bärnighausen T
2. Liu Y
3. Zhang X
4. Sauerborn R
Willingness to pay for social health insurance among informal sector workers in Wuhan, China: a contingent valuation study.; BMC health services research; Vol 7. 2007.
1. Xie C
2. Xue M
3. Naik A
4. Lin A
5. Schwarz E
6. Guldberg R
7. R J
8. Zhang X
Cox-2 deficient bone healing environment impairs initiation of periosteum dependent endochondral bone repair. (under review in JBMR); JBMR (under review). 2007 Jan 01.
1. Reynolds DG
2. Hock C
3. Shaikh S
4. Jacobson J
5. Zhang X
6. Rubery PT
7. Beck C
8. O'Keefe RJ
9. Lerner A
10. Schwarz EM
Radiographic Prediction of Biomechanical Strength in Structural Bone Grafts.; J. Biomech. 40(14):3178-86.. 2007 Jan 01.
1. O'Keefe RJ
2. Tiyapatanaputi P
3. Xie C
4. Li TF
5. Clark C
6. Zuscik MJ
7. Chen D
8. Drissi H
9. Schwarz E
10. Zhang X
COX-2 has a critical role during incorporation of structural bone allografts.; Annals of the New York Academy of Sciences; Vol 1068. 2006 Apr.
1. Zhang X
2. Sun B
3. Friend RH
4. Guo H
5. Nau D
6. Giessen H
Metallic photonic crystals based on solution-processible gold nanoparticles.; Nano letters; Vol 6(4). 2006 Apr.
1. Murugan R
2. Ramakrishna S
Nano-featured scaffolds for tissue engineering: a review of spinning methodologies.; Tissue engineering; Vol 12(3). 2006 Mar.
1. Robertson G
2. Xie C
3. Chen D
4. Awad H
5. Schwarz EM
6. O'Keefe RJ
7. Zhang X
Alteration of femoral bone morphology and density in cox-2-/- mice.; Bone Oct.. 2006 Jan 01.
1. Zhang X
2. Xie C
3. Lin AS
4. Ito H
5. Awad H
6. Lieberman JR
7. Rubery PT
8. Schwarz EM
9. O'Keefe RJ
10. Guldberg RE
Periosteal progenitor cell fate in segmental cortical bone graft transplantations: implications for functional tissue engineering.; Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research; Vol 20(12). 2005 Dec.
1. Zhang X
2. Naik A
3. Xie C
4. Reynolds D
5. Palmer J
6. Lin A
7. Awad H
8. Guldberg R
9. Schwarz E
10. O'Keefe R
Periosteal stem cells are essential for bone revitalization and repair.; Journal of musculoskeletal & neuronal interactions; Vol 5(4). 2005 Oct.
1. Koefoed M
2. Ito H
3. Gromov K
4. Reynolds DG
5. Awad HA
6. Rubery PT
7. Ulrich-Vinther M
8. Soballe K
9. Guldberg RE
10. Lin AS
11. O'Keefe RJ
12. Zhang X
13. Schwarz EM
Biological effects of rAAV-caAlk2 coating on structural allograft healing.; Molecular therapy : the journal of the American Society of Gene Therapy; Vol 12(2). 2005 Aug.
1. Wei X
2. Zhang X
3. Zuscik MJ
4. Drissi MH
5. Schwarz EM
6. O'Keefe RJ
Fibroblasts express RANKL and support osteoclastogenesis in a COX-2-dependent manner after stimulation with titanium particles.; Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research; Vol 20(7). 2005 Jul.
1. Carmouche JJ
2. Puzas JE
3. Zhang X
4. Tiyapatanaputi P
5. Cory-Slechta DA
6. Gelein R
7. Zuscik M
8. Rosier RN
9. Boyce BF
10. O'Keefe RJ
11. Schwarz EM
Lead exposure inhibits fracture healing and is associated with increased chondrogenesis, delay in cartilage mineralization, and a decrease in osteoprogenitor frequency.; Environmental health perspectives; Vol 113(6). 2005 Jun.
1. Clark CA
2. Schwarz EM
3. Zhang X
4. Ziran NM
5. Drissi H
6. O'Keefe RJ
7. Zuscik MJ
Differential regulation of EP receptor isoforms during chondrogenesis and chondrocyte maturation.; Biochemical and biophysical research communications; Vol 328(3). 2005 Mar 18.
1. Ito H
2. Koefoed M
3. Tiyapatanaputi P
4. Gromov K
5. Goater JJ
6. Carmouche J
7. Zhang X
8. Rubery PT
9. Rabinowitz J
10. Samulski RJ
11. Nakamura T
12. Soballe K
13. O'Keefe RJ
14. Boyce BF
15. Schwarz EM
Remodeling of cortical bone allografts mediated by adherent rAAV-RANKL and VEGF gene therapy.; Nature medicine; Vol 11(3). 2005 Mar.
1. Gu X
2. Feng Y
3. Shi C
4. Li M
5. Fu Z
6. Zhang X
Antiapoptotic mechanism of insulin in reoxygenation-induced injury in cultured cardiomyocytes of neonatal rats.; Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban; Vol 25(6). 2005.
1. Guldberg RE
2. Oest M
3. Lin AS
4. Ito H
5. Chao X
6. Gromov K
7. Goater JJ
8. Koefoed M
9. Schwarz EM
10. O'Keefe RJ
11. Zhang X
Functional integration of tissue-engineered bone constructs.; Journal of musculoskeletal & neuronal interactions; Vol 4(4). 2004 Dec.
1. Tiyapatanaputi P
2. Rubery PT
3. Carmouche J
4. Schwarz EM
5. O'keefe RJ
6. Zhang X
A novel murine segmental femoral graft model.; Journal of orthopaedic research : official publication of the Orthopaedic Research Society; Vol 22(6). 2004 Nov.
1. Li TF
2. Zuscik MJ
3. Ionescu AM
4. Zhang X
5. Rosier RN
6. Schwarz EM
7. Drissi H
8. O'Keefe RJ
PGE2 inhibits chondrocyte differentiation through PKA and PKC signaling.; Experimental cell research; Vol 300(1). 2004 Oct 15.
1. Zhang X
2. Ziran N
3. Goater JJ
4. Schwarz EM
5. Puzas JE
6. Rosier RN
7. Zuscik M
8. Drissi H
9. O'Keefe RJ
Primary murine limb bud mesenchymal cells in long-term culture complete chondrocyte differentiation: TGF-beta delays hypertrophy and PGE2 inhibits terminal differentiation.; Bone; Vol 34(5). 2004 May.
1. Bukata S
2. Gelinas J
3. Wei X
4. Rosier RN
5. Puzas JE
6. Zhang X
7. Schwarz EM
8. Song XR
9. Griswold DE
10. O'Keefe RJ
PGE2 and IL-6 production by fibroblasts in response to titanium wear debris particles is mediated through a COX-2 dependent pathway. .; J. of Orthopaedic Research.. 2004 Jan 01.
1. Tiyapatanaputi P
2. Rubery PT
3. Carmouche J
4. Schwarz EM
5. O'Keefe RJ
6. Zhang X
A Novel Murine Segmental Femoral Graft Model. J. of Othopaedic Research.; J. of Othopaedic Research.. 2004 Jan 01.
1. Bukata SV
2. Gelinas J
3. Wei X
4. Rosier RN
5. Puzas JE
6. Zhang X
7. Schwarz EM
8. Song XY
9. Griswold DE
10. O'Keefe RJ
PGE2 and IL-6 production by fibroblasts in response to titanium wear debris particles is mediated through a Cox-2 dependent pathway.; Journal of orthopaedic research : official publication of the Orthopaedic Research Society; Vol 22(1). 2004 Jan.
1. Li X
2. Ionescu AM
3. Schwarz EM
4. Zhang X
5. Drissi H
6. Puzas JE
7. Rosier RN
8. Zuscik MJ
9. O'Keefe RJ
Smad6 is induced by BMP-2 and modulates chondrocyte differentiation.; Journal of orthopaedic research : official publication of the Orthopaedic Research Society; Vol 21(5). 2003 Sep.
1. Flick LM
2. Weaver JM
3. Ulrich-Vinther M
4. Abuzzahab F
5. Zhang X
6. Dougall WC
7. Anderson D
8. O'Keefe RJ
9. Schwarz EM
Effects of receptor activator of NFkappaB (RANK) signaling blockade on fracture healing.; Journal of orthopaedic research : official publication of the Orthopaedic Research Society; Vol 21(4). 2003 Jul.
1. Flick LM
2. Weaver JM
3. Ulrich-Vinther M
4. Abuzzahab F
5. Zhang X
6. Dougal WC
7. Anderson D
8. O'Keefe RJ
9. Schwarz EM
Effects of receptor activator of NFkB (RANK) signaling blockade on fracture healing.; J. of Orthopaedic Research.. 2003 Jan 01.
1. Zhang X
2. Schwarz EM
3. Young DA
4. Puzas JE
5. Rosier RN
6. O'Keefe RJ
Cyclooxygenase-2 regulates mesenchymal cell differentiation into the osteoblast lineage and is critically involved in bone repair.; The Journal of clinical investigation; Vol 109(11). 2002 Jun.
1. Mungo DV
2. Zhang X
3. O'Keefe RJ
4. Rosier RN
5. Puzas JE
6. Schwarz EM
COX-1 and COX-2 expression in osteoid osteomas.; Journal of orthopaedic research : official publication of the Orthopaedic Research Society; Vol 20(1). 2002 Jan.
1. Zhang X
2. Schwarz EM
3. Young DA
4. Puzas JE
5. Rosier RN
6. O'Keefe RJ
COX-2 Regulates Mesenchymal Cell Differentiation into Osteoblast Lineage and is Critically Involved in Bone Repair. Journal of Clinical Investigation; . 2002 Jan 01.
1. Zhang X
2. Morham SG
3. Langenback R
4. Young DA
5. Xing L
6. Boyce BF
7. Puzas JE
8. Rosier RN
9. O'Keefe RJ
10. Schwarz EM
Evidence for a 4 Direct Role of COX-2 in Implant Wear Debris Induced Osteolysis; J. Bone. Min. Res.; Vol 16 (4), pp. 660-669. 2001 Jan 01.
1. Zhang X
2. Zhang Y
3. Schwarz E
4. O'Keefe RJ
The role of COX-2 in bone repair.; Current opinion in Orthopaedics.. 2001 Jan 01.
1. Zhang X
2. Morham SG
3. Langenbach R
4. Baggs RB
5. Young DA
Lack of cyclooxygenase-2 inhibits growth of teratocarcinomas in mice.; Experimental cell research; Vol 254(2). 2000 Feb 1.
1. Zhang X
2. Morham SG
3. Langenbach R
4. Young DA
Malignant transformation and antineoplastic actions of nonsteroidal antiinflammatory drugs (NSAIDs) on cyclooxygenase-null embryo fibroblasts.; The Journal of experimental medicine; Vol 190(4). 1999 Aug 16.