News
News
Tara Capece and Patrick Murphy Appointed to Immunology Training Grant
Thursday, August 15, 2013
CVBI students, Tara Capece (Minsoo Kim lab) and Patrick Murphy (Rusty Elliot lab), were appointed to a position on the Immunology Training Grant (T32 AI007285). There was considerable competition with many strong candidates. The center would like to congratulate both on such a distinct honor.
CVBI Postdoctoral Fellow Receives Vaccine Fellowship Award
Tuesday, July 2, 2013
Milan Popovic, a post-doctoral fellow in Minsoo Kim's Lab, was awarded the 2013 Rochester Vaccine Fellowship award. Selection for the fellowship was a unanimous decision by three independent reviewers who praised Milan for his outstanding achievement in vaccine-related research.
Mosmann Awarded Novartis Prize for Basic Immunology
Monday, July 1, 2013
Tim R. Mosmann, Ph.D., Director of the David H. Smith Center for Vaccine Biology and Immunology at the University of Rochester Medical Center, was awarded the 2013 Novartis Prize for Basic Immunology. He shares the prize, which is awarded every three years for breakthrough contributions to the fields of basic and clinical immunology, with Robert L. Coffman, Ph.D., Vice President and Chief Scientific Officer at Dynavax.
The prize was awarded for Mosmann and Coffman’s research on how the body responds to different invaders, for example, bacteria versus parasitic worms. In the early 1980’s, they zeroed in on a group of white blood cells called helper T cells or TH cells, which communicate with other cells to activate the immune system and wipe out intruders. They discovered that TH cells fall into two distinct groups: TH1 cells, designed to eliminate bacteria and viruses; and TH2 cells, which are more effective against extracellular organisms, like worms and other parasites.
When Tim started this research, scientists thought that helper T cells could be divided into at least two subgroups, but no one had been able to prove this,
said Stephen Dewhurst, Ph.D., chair of the Department of Microbiology and Immunology at the Medical Center. Tim elegantly showed that these cells could be divided into two subsets that produced different secreted proteins (cytokines) and that had different functions – a finding that profoundly changed the way people think about the immune system.
Stephen Dewhurst Named Vice Dean for Research at UR School of Medicine and Dentistry
Thursday, May 2, 2013
Stephen Dewhurst, Ph.D., has been named vice dean for research at the University of Rochester School of Medicine and Dentistry. A faculty member since 1990 and past senior associate dean for basic research, Dewhurst will lead the School’s research strategic planning process and help advance its research priorities by identifying areas of excellence in which to make strategic investments; strengthening the research infrastructure; improving education and training; and promoting collaborations and alliances that will result in increased research funding.
Tara Capece Wins Second Place at Graduate Student Society Poster Competition
Wednesday, May 1, 2013
Tara Capece, a CVBI student in Minsoo Kim lab, won Second Place at the Graduate Student Society Poster Competition in recognition of outstanding presentation of thesis work The competition was held in the Sarah Flaum Atrium in April and involved students from all graduate programs at the University of Rochester Medical Center. Congratulations Tara!
Michael R. Elliott Receives 2012 Creative and Novel Ideas in HIV Research Grant
Friday, December 7, 2012
Michael R. Elliott, Ph.D. was recently announced as a recipient of a Creative and Novel Ideas in HIV Research (CNIHR) research grant at the XIX International AIDS Conference in Washington D.C. The CNIHR program is jointly sponsored by the National Institutes of Health (NIH), the NIH-supported Centers for AIDS Research (CFARs) and the International AIDS Society (IAS) with the aim to promote innovative research and novel ideas from early stage investigators whose primary focus has previously been in fields of scientific inquiry other than HIV. Dr. Elliott will work with Stephen Dewhurst, Ph.D. to complete a research project, entitled Apoptotic cell clearance signaling and HIV-associated inflammation.
An interview with Dr. Elliott describing this project can be viewed below:
Long-Term Health Effects of Environmental Factors Is Focus of New $1.75-Million Study
Wednesday, August 3, 2011
How exposure to chemicals and other environmental factors from the earliest months of life – even before we are born – affect our long-term health is the subject of a new five-year study by a scientist at the University of Rochester Medical Center.
B. Paige Lawrence, Ph.D., associate professor of Environmental Medicine and of Microbiology and Immunology, has been awarded $1.75 million by the National Institutes of Health to study how early exposure to factors in the environment affect our immune system.
Researchers Seek to Make Cavity-Causing Bacteria Self-Destruct
Tuesday, January 8, 2008
The ability of Streptococcus mutans (S. mutans) to survive in acid is one reason that the species is the main driver of tooth decay worldwide. Past research has shown that this ability has several components including a bacterial enzyme called fatty acid biosynthase M (FabM), which when shut down, makes S. mutans almost precisely 10,000 times more vulnerable to acid damage.
Our first goal is to force the major bacterium behind tooth decay to
destroy itself with its own acid as soon as it eats sugar,
said Robert G. Quivey, Ph.D.,
professor of Microbiology & Immunology at the University of Rochester Medical Center and principal investigator for the grant. After that, this line of work
could help lead to new anti-bacterial combination therapies for many infections that have become resistant to antibiotics.
Quivey's partners in the grant application were Elizabeth Grayhack, Ph.D., research associate professor of Biochemistry & Biophysics, Robert Marquis, Ph.D., professor of Microbiology & Immunology, and Eric Phizicky, Ph.D., professor of Biochemistry & Biophysics.
Protein Helps Immune System Mount Instant Strike
Against Deadly Flu Viruses
Friday, February 20, 2004
Researchers at the University of Rochester have identified a protein in the immune system that appears to play a crucial role in protecting against deadly forms of influenza, and may be particularly important in protecting against emerging flu viruses like the avian flu. The researchers believe that a vaccine made with a live but weakened strain of flu virus - such as the inhaled flu vaccine introduced last year - may activate this part of the immune system and offer the best defense against avian flu.
The findings demonstrate that when confronted by a potentially deadly flu strain, an effective first strike by T cells in the lungs can mean the difference between life and death. To immunologist David Topham, Ph.D., assistant professor of Microbiology and Immunology at the University of Rochester and lead author of the study, the findings reveal something else: a shortcoming in the world's most widely administered flu vaccines.
Instant StrikeAgainst Deadly Flu Viruses