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Irene B. Perillo, M.D.

Irene B. Perillo, M.D.

Pulmonary & Critical Care Medicine

5 out of 5 stars
UR Medicine Faculty The University of Rochester Medical Faculty Group (URMFG) consists of over 900 specialist and primary care providers spanning 19 departments. URMFG is certified by the National Committee for Quality Assurance.
Accountable Health Partner Accountable Health Partners (AHP) is a network of over 2,000 community and UR medical faculty and a dozen leading hospitals throughout the region. AHP offers a full range of care.
Accepting New Patients



Pulmonary Clinic

601 Elmwood Avenue, 3rd Floor
Rochester, NY 14642

About Me

Certified Specialties

Critical Care Medicine - American Board of Internal Medicine

Pulmonary Disease - American Board of Internal Medicine

Faculty Appointments

Professor of Clinical Medicine - Department of Medicine, Pulmonary Diseases and Critical Care (SMD)


Residency & Fellowship

Fellowship, Pulmonary and Critical Care Medicine, University of Rochester Medical Center. 1995 - 1998

Internship, Internal Medicine, University of Rochester Medical Center. 1992 - 1993

Residency, Internal Medicine, University of Rochester Medical Center. 1992 - 1995


MD | Suny Health Science Center At Syracuse. 1992


BEACON Award for Excellence on Critical Care @ Highland Hospital Intensive Care Unit 2007

Post-Doctoral Trainee, NIH/NIEHS Training Grant, "Training in Environmental Toxicology". 1997 - 1999

Young Investigator Award of the American College of Chest Physicians 1997

Cecil Lehman Mayer Research Award of the American College of Chest Physicians (Finalist) 1997

Manufacturer Hanover Trust Scholarship 1985 - 1989

New York State Regents Scholarship 1984 - 1989


Journal Articles

Changes in Markers of Epithelial Permeability and Inflammation in Chronic Smokers Switching to a Non-burning Tobacco Device (Eclipse)

Stewart JC, Hyde RW, Boscia J, Chow MY, O'Mara RE, Perillo I, Pietropaoli I, Smith CJ, Torres A, Utell MU, Frampton MW.

Nicotine & Tobacco Research. 2006; 8: 773-783.

An approach to interpreting spirometry.

Barreiro TJ, Perillo I

American family physician.. 2004 March 169 (5):1107-14. Epub 1900 01 01.

Chemiluminescent Measurements of Nitric Oxide Pulmonary Diffusing Capacity and Alveolar Production in Humans

Perillo IB, RW Hyde, AJ Olszowka, AP Pietropaoli, LM Frasier, A Torres, PT Perkins, RE Foster, MJ Utell, MW Frampton.

J Appl Physiol: Respir Environ Exercise Physiol. 2001; 91.

Exhaled nitric oxide does not provide a marker of vascular endothelial function in healthy humans.

Pietropaoli AP, Perkins PT, Perillo IB, Hyde RW

American journal of respiratory and critical care medicine.. 2000 June 161 (6):2113-4. Epub 1900 01 01.

Thrombotic Thrombocytopenic Purpura in Pulmonary-Renal Syndrome

Panoskaltis N, Derman M, IB Perillo, Brennan JK.

American J Hematology. 2000; 65: 50-55.

Lung injury and inflammation in smokers: effects of switching to a "new" cigarette.

Frampton, MW, RW Hyde, A Torres, IB Perillo, A Pietropaoli, R O'Hara. M Aziadniv, L Frazier, D Speers, C Smith, M Utell.

European Respiratory Journal. 2000; 16.

Case Report: Pulmonary Hyalinizing Granuloma

Boscia JA: IB Perillo; PC Levy.

Chest. 1999; 116(4), suppl 2.

Rate of nitric oxide production by the peripheral airways of human lungs

Geigel, EJ; RW Hyde; IB Perillo,;A Torres; PT Perkins; AP Pietropaoli; LM Frasier;MW Frampton; MJ Utell.

J Appl Physiol: Respirat Environ Exercise Physiol. 1999; 86:211-221.

Simultaneous measurements of nitric oxide (NO) production by upper and lower airways of man

Pietropaoli, AP; IB Perillo; A Torres; PT Perkins; MJ Utell; MW Frampton; and RW Hyde.

J Appl Physiol: Respirat Environ Exercise Physiol. 1999; 87(4): 1532-1542.

Smokers Have Reduced Nitic Oxide Production by the Conducting Airways but Normal Levels in the Alveoli.

AP Pietropaoli, IB Perillo, LM Frasier, DM Speers, MW Frampton, MJ Utell, RW Hyde.

Inhalation Toxicology. .


Mechanical Ventilation (2007)

Chapter: Flexible Bronchoscopy in Mechanically Ventilated Patients

Authors: Perillo IB, Dudek G, MJ Utell

Publisher: Elsevier Publishing, New York 2007

Ratings & Comments

At URMC, we believe that patients should be empowered to make the right decisions regarding their personal healthcare. To do so, transparency is critical. URMC partners with Press Ganey, to survey our patients about all aspects of their care experience. We are now putting this pertinent information at your fingertips by displaying star ratings for our providers along with anonymous patient comments on our website. This will help you make better-informed choices about how and with whom you seek care. Click here to learn more about the surveys used to generate this vital information. Learn more about our survey process.


During this visit, did this provider spend enough time with you?

5.0 stars

During this visit, did this provider show respect for what you had to say?

5.0 stars

During this visit, did this provider give you easy to understand information about these health questions or concerns?

5.0 stars

During this visit, did this provider listen carefully to you?

5.0 stars

During this visit, did this provider explain things in a way that was easy to understand?

4.9 stars

Patient Comments

5.0 stars

Dr. Perillo is smart, caring and listened and works with me to provide great care -

Jun 30, 2023

5.0 stars

Very thorough.

Jun 15, 2023

5.0 stars

Have over repeated visits, established a positive trust with this team.

Apr 11, 2023

5.0 stars

[...] Was seeing another specialist that certainly didn't know or care as much as Dr. Perillo does.

Dec 20, 2022

5.0 stars

This was my first time meeting provider, my usual provider left URMC. I was very please.

May 16, 2022

Dr Perillo made follow-up plans for more testing [...] I would recommend Dr. Perillo as a physician [...]

Apr 01, 2022