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David A. DiLoreto, M.D., Ph.D.

David A. DiLoreto, M.D., Ph.D.


Connect with David A. DiLoreto, M.D., Ph.D.

About Me

Faculty Appointments

Professor - Department of Ophthalmology (SMD)

Chair - Department of Ophthalmology (SMD)

Professor - Center for Visual Science A&S (RC) - Joint


Post-doctoral Training & Residency

Fellowship, Johns Hopkins University Hospital. 2001 - 2003

Fellowship, Instructor, Wilmer Eye Institute-Johns Hopkins University. 2001 - 2003

Residency, Ophthalmology, University of Southern California. 1998 - 2001

Residency, Resident, USC/Doheny Eye Institute. 1998 - 2001

Internship, Internal Medicine, Highland Hospital of Rochester. 1997 - 1998


MD | University of Rochester School of Medicine/Dentistry. 1997

PHD | University of Rochester School of Medicine/Dentistry. 1995


Commitment to providing employment opportunities for individuals with disabilities, Flaum Eye Institute, New Regional Award.

Inclusive Workforce Development Award, Department of Ophthalmology, Flaum Eye Institute; Stronger as One Diversity Award.

Readers Choice Award: One of the Best Health Care Services in the Region.

Retina 150: A select group of 150 innovators in the field of medical and surgical retina.

Resident Teaching Award.

Didactic Teaching Award.

Resident Teaching Award by a Fellow.

Outstanding Research Paper by a Senior Retina Fellow.

Sheard Sanford Medical Student Award.


Journal Articles

Inner limiting Membrane Peel Extends Calcium Imaging of Retinal Ganglion Cell Activity Beyond the Fovea in Non-Human Primate.

Baez HC, LaPorta JM, Walker AD, Fischer WS, Hollar R, Patterson S, DiLoreto DA, Gullapalli V, McGregor JE

bioRxiv : the preprint server for biology.. 2024 June 2 Epub 06/02/2024.

Contributed Session I: Inner limiting membrane peel extends vivo calcium imaging of ganglion cells (RGC) beyond the fovea in non-human primate.

Baez H, Jennifer L, Amber W, William F, Rachel H, Sara P, David D, Vamsi G, Juliette M

Journal of vision.. 2023 December 123 (15):70. Epub 1900 01 01.

Cost-Utility Comparison of Bevacizumab and Aflibercept in the Treatment of Central or Hemiretinal Vein Occlusion in the SCORE2 Trial.

Kymes SM, Oden NL, VanVeldhuisen PC, Scott IU, Ip MS, Blodi BA, King J,

JAMA ophthalmology.. 2023 May 11 Epub 05/11/2023.

Long-term Outcomes of Adding Lutein/Zeaxanthin and ?-3 Fatty Acids to the AREDS Supplements on Age-Related Macular Degeneration Progression: AREDS2 Report 28.

Chew EY, Clemons TE, Agrón E, Domalpally A, Keenan TDL, Vitale S, Weber C, Smith DC, Christen W,

JAMA ophthalmology.. 2022 June 2 Epub 06/02/2022.

Lapses in Care Among Patients Assigned to Ranibizumab for Proliferative Diabetic Retinopathy: A Post Hoc Analysis of a Randomized Clinical Trial.

Maguire MG, Liu D, Bressler SB, Friedman SM, Melia M, Stockdale CR, Glassman AR, Sun JK,

JAMA ophthalmology.. 2021 October 21 Epub 10/21/2021.

Steroid Allergy in a Patient With Behçet's Disease.

Harrison BM, Looney RJ, Williams ZR, DiLoreto DA

Ophthalmic surgery, lasers & imaging retina.. 2021 August 52 (8):447-449. Epub 08/01/2021.

Spontaneous Resolution of a Choroidal Mass: A Case Series.

Bianchi JI, Nirwan RS, Fulda Graue E, Ross-Hirsch A, Lopez-Rubio S, DiLoreto DA, Singh AD

Ocular oncology and pathology.. 2020 October 6 (5):305-310. Epub 09/11/2020.

Quantitative Comparison of Fundus Images by Two Ultra-Wide Field Fundus Cameras.

Chen A, Dang S, Chung MM, Ramchandran RS, Bessette AP, DiLoreto DA, Kleinman DM, Sridhar J, Wykoff CC, Kuriyan AE

Ophthalmology. Retina.. 2020 August 28 Epub 08/28/2020.

Imaging Transplanted Photoreceptors in Living Nonhuman Primates with Single-Cell Resolution.

Aboualizadeh E, Phillips MJ, McGregor JE, DiLoreto DA, Strazzeri JM, Dhakal KR, Bateman B, Jager LD, Nilles KL, Stuedemann SA, Ludwig AL, Hunter JJ, Merigan WH, Gamm DM, Williams DR

Stem cell reports.. 2020 July 21 Epub 07/21/2020.

Natural History of Drusenoid Pigment Epithelial Detachment Associated with Age-Related Macular Degeneration: Age-Related Eye Disease Study 2 Report No. 17.

Yu JJ, Agrón E, Clemons TE, Domalpally A, van Asten F, Keenan TD, Cukras C, Chew EY,

Ophthalmology.. 2019 February 126 (2):261-273. Epub 08/22/2018.

Cellular-scale evaluation of induced photoreceptor degeneration in the living primate eye.

Walters S, Schwarz C, Sharma R, Rossi EA, Fischer WS, DiLoreto DA, Strazzeri J, Nelidova D, Roska B, Hunter JJ, Williams DR, Merigan WH

Biomedical optics express.. 2019 January 110 (1):66-82. Epub 12/05/2018.

Progression of Geographic Atrophy in Age-related Macular Degeneration: AREDS2 Report Number 16.

Keenan TD, Agrón E, Domalpally A, Clemons TE, van Asten F, Wong WT, Danis RG, Sadda S, Rosenfeld PJ, Klein ML, Ratnapriya R, Swaroop A, Ferris FL, Chew EY,

Ophthalmology.. 2018 December 125 (12):1913-1928. Epub 07/27/2018.

Plasma Vascular Endothelial Growth Factor Concentrations after Intravitreous Anti-Vascular Endothelial Growth Factor Therapy for Diabetic Macular Edema.

Jampol LM, Glassman AR, Liu D, Aiello LP, Bressler NM, Duh EJ, Quaggin S, Wells JA, Wykoff CC,

Ophthalmology.. 2018 July 125 (7):1054-1063. Epub 03/07/2018.

In Vivo Adaptive Optics Ophthalmoscopy Correlated with Histopathologic Results in Cancer-Associated Retinopathy.

Williams ZR, Rossi EA, DiLoreto DA

Ophthalmology. Retina.. 2018 February 2 (2):143-151. Epub 09/09/2017.


Sangave AA, Gearinger MD, Diloreto DA

Retinal cases & brief reports.. 2017 11 (1):1-3. Epub 1900 01 01.

Central Retinal Artery Occlusion With Subsequent Central Retinal Vein Occlusion in Biopsy-Proven Giant Cell Arteritis.

Williams ZR, Wang X, DiLoreto DA

Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society.. 2016 September 36 (3):290-1. Epub 1900 01 01.

The Association of Statin Use with Cataract Progression and Cataract Surgery: The AREDS2 Report Number 8.

, Al-Holou SN, Tucker WR, Agrón E, Clemons TE, Sperduto RD, Ferris FL, Chew EY

Ophthalmology.. 2016 April 123 (4):916-7. Epub 12/11/2015.

Association of Baseline Visual Acuity and Retinal Thickness With 1-Year Efficacy of Aflibercept, Bevacizumab, and Ranibizumab for Diabetic Macular Edema.

Wells JA, Glassman AR, Jampol LM, Aiello LP, Antoszyk AN, Baker CW, Bressler NM, Browning DJ, Connor CG, Elman MJ, Ferris FL, Friedman SM, Melia M, Pieramici DJ, Sun JK, Beck RW,

JAMA ophthalmology.. 2016 February 134 (2):127-34. Epub 1900 01 01.

Assessing the Effect of Personalized Diabetes Risk Assessments During Ophthalmologic Visits on Glycemic Control: A Randomized Clinical Trial.

Aiello LP, Ayala AR, Antoszyk AN, Arnold-Bush B, Baker C, Bressler NM, Elman MJ, Glassman AR, Jampol LM, Melia M, Nielsen J, Wolpert HA,

JAMA ophthalmology.. 2015 August 133 (8):888-96. Epub 1900 01 01.

Aflibercept, bevacizumab, or ranibizumab for diabetic macular edema.

The New England journal of medicine.. 2015 March 26372 (13):1193-203. Epub 02/18/2015.

Sustained delivery fluocinolone acetonide vitreous implants: long-term benefit in patients with chronic diabetic macular edema.

Cunha-Vaz J, Ashton P, Iezzi R, Campochiaro P, Dugel PU, Holz FG, Weber M, Danis RP, Kuppermann BD, Bailey C, Billman K, Kapik B, Kane F, Green K,

Ophthalmology.. 2014 October 121 (10):1892-903. Epub 06/14/2014.

Focal damage to macaque photoreceptors produces persistent visual loss.

Strazzeri JM, Hunter JJ, Masella BD, Yin L, Fischer WS, Diloreto DA, Libby RT, Williams DR, Merigan WH

Experimental eye research.. 2014 February 119 :88-96. Epub 12/05/2013.

Methods and reproducibility of grading optimized digital color fundus photographs in the Age-Related Eye Disease Study 2 (AREDS2 Report Number 2).

Danis RP, Domalpally A, Chew EY, Clemons TE, Armstrong J, SanGiovanni JP, Ferris FL,

Investigative ophthalmology & visual science.. 2013 July 854 (7):4548-54. Epub 07/08/2013.

Migration of intravitreal dexamethasone implant to anterior chamber.

Gullapalli VK, DiLoreto DA

Retinal cases & brief reports.. 2013 7 (1):111-3. Epub 1900 01 01.

Evaluation of visual acuity measurements after autorefraction vs manual refraction in eyes with and without diabetic macular edema.

Sun JK, Qin H, Aiello LP, Melia M, Beck RW, Andreoli CM, Edwards PA, Glassman AR, Pavlica MR,

Archives of ophthalmology.. 2012 April 130 (4):470-9. Epub 12/12/2011.

Infectious endophthalmitis in adult eyes receiving Boston type I keratoprosthesis.

Ramchandran RS, Diloreto DA, Chung MM, Kleinman DM, Plotnik RP, Graman P, Aquavella JV

Ophthalmology.. 2012 April 119 (4):674-81. Epub 01/23/2012.

Comparison of film and digital fundus photographs in eyes of individuals with diabetes mellitus.

Gangaputra S, Almukhtar T, Glassman AR, Aiello LP, Bressler N, Bressler SB, Danis RP, Davis MD,

Investigative ophthalmology & visual science.. 2011 August 352 (9):6168-73. Epub 08/03/2011.

Intravitreal injection of AAV2 transduces macaque inner retina.

Yin L, Greenberg K, Hunter JJ, Dalkara D, Kolstad KD, Masella BD, Wolfe R, Visel M, Stone D, Libby RT, Diloreto D, Schaffer D, Flannery J, Williams DR, Merigan WH

Investigative ophthalmology & visual science.. 2011 April 2552 (5):2775-83. Epub 04/25/2011.

SCORE Study Report 7: incidence of intravitreal silicone oil droplets associated with staked-on vs luer cone syringe design.

Scott IU, Oden NL, VanVeldhuisen PC, Ip MS, Blodi BA, Antoszyk AN,

American journal of ophthalmology.. 2009 November 148 (5):725-732.e7. Epub 08/11/2009.

A randomized trial comparing the efficacy and safety of intravitreal triamcinolone with observation to treat vision loss associated with macular edema secondary to central retinal vein occlusion: the Standard Care vs Corticosteroid for Retinal Vein Occlusion (SCORE) study report 5.

Ip MS, Scott IU, VanVeldhuisen PC, Oden NL, Blodi BA, Fisher M, Singerman LJ, Tolentino M, Chan CK, Gonzalez VH,

Archives of ophthalmology.. 2009 September 127 (9):1101-14. Epub 1900 01 01.

Retinal arteriolar spasm during transient monocular visual loss in eosinophilic vasculitis.

Stasi K, Ramchandran RS, Rao NA, Feldon SE, DiLoreto DA

Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society.. 2009 March 29 (1):58-61. Epub 1900 01 01.

Retinal Arteriolar Spasm During Tansient Monocular Visual Loss in a Patient with Eosinophilic Vasculitus

Stasi, K., Ramchandran, R., Rao, N., Feldon, S.

Journal of Neuro-Ophthalmology. 2009; .

Infectious Endophthalmitis in Adult Eyes Receiving Dohlman Type I Keratoprosthesis.

DiLoreto, DA., Ramchandran, R., Aquavella, JV., Plotnik, RP., Chung, M., Kleinman, DM., Graman, P.

Invest. Ophthalmol. Vis. Sci. XX: X-Abstract XXX, 2009. 2009; .

Optical coherence tomography measurements and analysis methods in optical coherence tomography studies of diabetic macular edema.

Browning DJ, Glassman AR, Aiello LP, Bressler NM, Bressler SB, Danis RP, Davis MD, Ferris FL, Huang SS, Kaiser PK, Kollman C, Sadda S, Scott IU, Qin H,

Ophthalmology.. 2008 August 115 (8):1366-71, 1371.e1. Epub 1900 01 01.

A 9 Year-Old Girl with Herpes Simplex Virus Type 2 Acute Retinal Necrosis Treated with Intravitreal Foscarnet". Ocular Immunol Inflamm.,

King, JS, Chung, M., DiLoreto, Jr. DA.

15:395-8. 2007; .

A 9 year-old girl with herpes simplex virus type 2 acute retinal necrosis treated with intravitreal foscarnet.

King J, Chung M, DiLoreto DA

Ocular immunology and inflammation.. 2007 15 (5):395-8. Epub 1900 01 01.

An ultrastructural study of the pathology of the retinal pigment epithelium, Bruch's membrane, and the choriocapillaris in the aged Fischer 344 rat.

DiLoreto DA, Luo C, Calkins DJ, del Cerro M

Current eye research.. 2006 September 31 (9):749-63. Epub 1900 01 01.

Nedergaard M. Müller cell domains in the retina" Invest. Ophthalmol. Vis. Sci. 47: E-Abstract 130.

DiLoreto DA, McDaniel T, Wang X,.

2006; .

Choroidal neovascularization after central retinal vein occlusion in a 47-year-old man.

DiLoreto DA, Goldberg MF, Bressler NM

Archives of ophthalmology.. 2004 September 122 (9):1398-401. Epub 1900 01 01.

Use of best and final visual acuity outcomes in ophthalmological research.

DiLoreto DA, Bressler NM, Bressler SB, Schachat AP

Archives of ophthalmology.. 2003 November 121 (11):1586-90. Epub 1900 01 01.

Idiopathic retinal vasculitis, aneurysms, and neuroretinitis (IRVAN) with preserved perfusion.

DiLoreto DA, Sadda SR

Retina.. 2003 August 23 (4):554-7. Epub 1900 01 01.

Late-onset bacterial endophthalmitis following glaucoma drainage implantation.

Francis BA, DiLoreto DA, Chong LP, Rao N

Ophthalmic surgery, lasers & imaging : the official journal of the International Society for Imaging in the Eye.. 2003 March 134 (2):128-30. Epub 1900 01 01.

Late Onset Bacteria Endophthalmitis Following Glaucoma Drainage Implanation

Francis BA; DiLoreto DA; Chong LP; Rao N.

Ophthalmic Surgery, Lasers & Imaging. 2003; 34(2): 128-130.

"Human Neural Retinal Transplants into Retinitis Pigmentosa: facts and controversy"

DiLoreto, DA, Jr., Del Cerro, M., Del Cerro, C., Lazar, ES.

Digital J Ophthalmol ( 2002; .

Solitary nonreactive choroidal tuberculoma in a patient with acquired immune deficiency syndrome.

DiLoreto DA, Rao NA

American journal of ophthalmology.. 2001 January 131 (1):138-40. Epub 1900 01 01.

The transplantation of human fetal neuroretinal cells in advanced retinitis pigmentosa patients: results of a long-term safety study.

Das T, del Cerro M, Jalali S, Rao VS, Gullapalli VK, Little C, Loreto DA, Sharma S, Sreedharan A, del Cerro C, Rao GN

Experimental neurology.. 1999 May 157 (1):58-68. Epub 1900 01 01.

Changes in visually guided behavior of Royal College of Surgeons rats as a function of age: a histologic, morphometric, and functional study.

DiLoreto DA, del Cerro C, Cox C, del Cerro M

Investigative ophthalmology & visual science.. 1998 May 39 (6):1058-63. Epub 1900 01 01.

Fluorescein as a marker for subretinal transplantation of human fetal neural retina.

DiLoreto DA, Das T, del Cerro C, Cox C, del Cerro M

Current eye research.. 1997 November 16 (11):1159-65. Epub 1900 01 01.

The first decade of continuous progress in retinal transplantation.

del Cerro M, Lazar ES, Diloreto D

Microscopy research and technique.. 1997 January 1536 (2):130-41. Epub 1900 01 01.

Cyclosporine treatment promotes survival of human fetal neural retina transplanted to the subretinal space of the light-damaged Fischer 344 rat.

DiLoreto D, del Cerro C, del Cerro M

Experimental neurology.. 1996 July 140 (1):37-42. Epub 1900 01 01.

Water escape performance of adult RCS dystrophic and congenic rats: a functional and histomorphometric study.

DiLoreto D, del Cerro M, Reddy SV, Janardhan S, Cox C, Wyatt J, Balkema GW

Brain research.. 1996 April 22717 (1-2):165-72. Epub 1900 01 01.

Transplantation of human fetal retinal pigment epithelium rescues photoreceptor cells from degeneration in the Royal College of Surgeons rat retina.

Little CW, Castillo B, DiLoreto DA, Cox C, Wyatt J, del Cerro C, del Cerro M

Investigative ophthalmology & visual science.. 1996 January 37 (1):204-11. Epub 1900 01 01.

Storage of human fetal retina in optisol prior to subretinal transplantation.

DiLoreto DA, del Cerro C, Lazar ES, Cox C, del Cerro M

Cell transplantation.. 1996 5 (5):553-61. Epub 1900 01 01.

Müller cell changes precede photoreceptor cell degeneration in the age-related retinal degeneration of the Fischer 344 rat.

DiLoreto DA, Martzen MR, del Cerro C, Coleman PD, del Cerro M

Brain research.. 1995 November 6698 (1-2):1-14. Epub 1900 01 01.

The intensity of the pupillary light reflex does not correlate with the number of retinal photoreceptor cells.

Kovalevsky G, DiLoreto D, Wyatt J, del Cerro C, Cox C, del Cerro M

Experimental neurology.. 1995 May 133 (1):43-9. Epub 1900 01 01.

A functional analysis of the age-related degeneration in the Fischer 344 rat.

DiLoreto D, Ison JR, Bowen GP, Cox C, del Cerro M

Current eye research.. 1995 April 14 (4):303-10. Epub 1900 01 01.

Neither intraocular grafts of retinal cell homogenates nor live non-retinal neurons produce behavioral recovery in rats with light-damaged retinas.

del Cerro M, DiLoreto D, Cox C, Lazar ES, Grover DA, del Cerro C

Cell transplantation.. 1995 4 (1):133-9. Epub 1900 01 01.

Cytomegalovirus infection of human retinal tissue: an in vivo model.

DiLoreto D, Epstein LG, Lazar ES, Britt WJ, del Cerro M

Laboratory investigation; a journal of technical methods and pathology.. 1994 July 71 (1):141-8. Epub 1900 01 01.

The influences of age, retinal topography, and gender on retinal degeneration in the Fischer 344 rat.

DiLoreto D, Cox C, Grover DA, Lazar E, del Cerro C, del Cerro M

Brain research.. 1994 June 6647 (2):181-91. Epub 1900 01 01.

A new procedure for fundus photography and fluorescein angiography in small laboratory animal eyes.

DiLoreto D, Grover DA, del Cerro C, del Cerro M

Current eye research.. 1994 February 13 (2):157-61. Epub 1900 01 01.

"Rejuvenation Through Transplantation: an historical review of Voronoff's work"

DiLoreto, DA, Jr.

J. U Rochester Med Ctr, 6:31-39,. 1994; .

Differentiation of Y79 retinoblastoma cells with pigment epithelial-derived factor and interphotoreceptor matrix wash: effects on tumorigenicity.

Seigel GM, Tombran-Tink J, Becerra SP, Chader GJ, Diloreto DA, del Cerro C, Lazar ES, del Cerro M

Growth factors.. 1994 10 (4):289-97. Epub 1900 01 01.

Human neural xenografts: progress in developing an in-vivo model to study human immunodeficiency virus (HIV) and human cytomegalovirus (HCMV) infection.

Epstein LG, Cvetkovich TA, Lazar ES, DiLoreto D, Saito Y, James H, del Cerro C, Kaneshima H, McCune JM, Britt WJ

Advances in neuroimmunology. 1994 4 (3):257-60. Epub 1900 01 01.

Transplantation of Y79 cells into rat eyes: an in vivo model of human retinoblastomas.

del Cerro M, Seigel GM, Lazar E, Grover D, del Cerro C, Brooks DH, DiLoreto D, Chader G

Investigative ophthalmology & visual science.. 1993 November 34 (12):3336-46. Epub 1900 01 01.

Neurotoxic effects of tumor necrosis factor alpha in primary human neuronal cultures are mediated by activation of the glutamate AMPA receptor subtype: implications for AIDS neuropathogenesis.

Gelbard HA, Dzenko KA, DiLoreto D, del Cerro C, del Cerro M, Epstein LG

Developmental neuroscience.. 1993 15 (6):417-22. Epub 1900 01 01.

"Rejuvenation Through Transplantation: an historical review of Voronoff's work"

DiLoreto, DA, Jr.

J. U Rochester Med Ctr, 6:31-39, 1994.


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