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Inna Hughes, M.D., Ph.D.

Inna Hughes, M.D., Ph.D.


Neurology, Pediatrics, Child Neurology

UR Medicine Faculty The University of Rochester Medical Faculty Group (URMFG) consists of over 900 specialist and primary care providers spanning 19 departments. URMFG is certified by the National Committee for Quality Assurance.
Accountable Health Partner Accountable Health Partners (AHP) is a network of over 2,000 community and UR medical faculty and a dozen leading hospitals throughout the region. AHP offers a full range of care.
Accepting New Patients


Appointment (585) 275-2808
Administrative (585) 275-9403
Administrative (585) 275-2808


Epilepsy Center

601 Elmwood Avenue, Box 673
Rochester, NY 14642

Pediatric Neurology

200 East River Road, 3rd Floor
Rochester, NY 14623

About Me

Professional Background

Inna Hughes, MD, PhD, is an Associate Professor of Child Neurology and Epilepsy at the University of Rochester. Her clinical interests are both in pediatric epilepsy and general child neurology. Dr. Hughes completed undergraduate studies at Williams College and graduated from Washington University i...
Inna Hughes, MD, PhD, is an Associate Professor of Child Neurology and Epilepsy at the University of Rochester. Her clinical interests are both in pediatric epilepsy and general child neurology. Dr. Hughes completed undergraduate studies at Williams College and graduated from Washington University in St Louis School of Medicine after completion of the combined MD, PhD program. She completed her Child Neurology residency training and a Pediatric Epilepsy fellowship at the University of Rochester Medical Center in Rochester, NY.

Dr. Hughes is board certified in Neurology with Special Qualification in Child Neurology and board certified in Epilepsy. She is an active member in the American Academy of Neurology, American Epilepsy Society, and the Child Neurology Society. She has several research interests including the development and genetics of childhood onset epilepsy syndromes, dietary therapy in children and teens, transition of care for young adults with epilepsy, and development of teaching and community programs to improve education and awareness for patients with epilepsy.

Certified Specialties

Epilepsy - American Board of Psychiatry & Neurology

Neurology with Special Qualification in Child Neurology - American Board of Psychiatry & Neurology

Faculty Appointments

Associate Professor - Department of Neurology, Epilepsy (SMD)

Associate Professor - Department of Pediatrics (SMD) - Joint


Residency & Fellowship

Fellowship, Epilepsy, University of Rochester Medical Center. 2014 - 2015

Residency, University of Rochester Medical Center. 2009 - 2012

Internship, Pediatrics, Golisano Children's Hospital-University of Rochester. 2007 - 2009


MD | Washington University School of Medicine. 2007


Upstate New York Regional Champions. 2011

Alpha Omega Alpha Society. 2011

Spencer T and Ann W. Olin Medical Scientist Fellow. 2007

Merlie Fine Sciences Travel Award. 2004

Viktor Hamburger Award. 2004

Graduate Student Presentation Award. 2004

Ruth L. Kirschstein National Research Service Award Individual Fellowship. 2004 - 2007

Honors in Biology, Magna cum Laude. 1999

Medical Scientist Training Program grant. 1999 - 2003

Minority Undergraduate Summer Internship Program. 1998

Acceleration to Excellence Scholarship. 1995 - 1997


Journal Articles

Seizure Frequency Process and Outcome Quality Measures: Quality Improvement in Neurology.

Munger Clary H, Josephson SA, Franklin G, Herman ST, Hopp JL, Hughes I, Meunier L, Moura LMVR, Parker-McFadden B, Pugh MJ, Schultz R, Spanaki MV, Bennett A, Baca C

Neurology.. 2022 April 598 (14):583-590. Epub 1900 01 01.

Genetic mosaicism, intrafamilial phenotypic heterogeneity, and molecular defects of a novel missense SLC6A1 mutation associated with epilepsy and ADHD.

Poliquin S, Hughes I, Shen W, Mermer F, Wang J, Mack T, Xu D, Kang JQ

Experimental neurology.. 2021 May 4 :113723. Epub 05/04/2021.

Quality improvement in neurology: Epilepsy Quality Measurement Set 2017 update.

Patel AD, Baca C, Franklin G, Herman ST, Hughes I, Meunier L, Moura LMVR, Munger Clary H, Parker-McFadden B, Pugh MJ, Schultz RJ, Spanaki MV, Bennett A, Josephson SA

Neurology.. 2018 October 3091 (18):829-836. Epub 10/03/2018.

Lineage-specific evolution of the vertebrate Otopetrin gene family revealed by comparative genomic analyses.

Hurle B, Marques-Bonet T, Antonacci F, Hughes I, Ryan JF, Comparative Sequencing Program N, Eichler EE, Ornitz DM, Green ED

BMC evolutionary biology. 2011 January 2411 :23. Epub 01/24/2011.

The timing and location of glial cell line-derived neurotrophic factor expression determine enteric nervous system structure and function.

Wang H, Hughes I, Planer W, Parsadanian A, Grider JR, Vohra BP, Keller-Peck C, Heuckeroth RO

The Journal of neuroscience : the official journal of the Society for Neuroscience.. 2010 January 2730 (4):1523-38. Epub 1900 01 01.

Identification of the Otopetrin Domain, a conserved domain in vertebrate otopetrins and invertebrate otopetrin-like family members.

Hughes I, Binkley J, Hurle B, Green ED, , Sidow A, Ornitz DM

BMC evolutionary biology. 2008 February 68 :41. Epub 02/06/2008.

Otopetrin 1 activation by purinergic nucleotides regulates intracellular calcium.

Hughes I, Saito M, Schlesinger PH, Ornitz DM

Proceedings of the National Academy of Sciences of the United States of America.. 2007 July 17104 (29):12023-8. Epub 07/02/2007.

Mixing model systems: using zebrafish and mouse inner ear mutants and other organ systems to unravel the mystery of otoconial development.

Hughes I, Thalmann I, Thalmann R, Ornitz DM

Brain research.. 2006 May 261091 (1):58-74. Epub 03/09/2006.

Microscale analysis of proteins in inner ear tissues and fluids with emphasis on endolymphatic sac, otoconia, and organ of Corti.

Thalmann I, Hughes I, Tong BD, Ornitz DM, Thalmann R

Electrophoresis.. 2006 April 27 (8):1598-608. Epub 1900 01 01.

Otopetrin 1 is required for otolith formation in the zebrafish Danio rerio.

Hughes I, Blasiole B, Huss D, Warchol ME, Rath NP, Hurle B, Ignatova E, Dickman JD, Thalmann R, Levenson R, Ornitz DM

Developmental biology.. 2004 December 15276 (2):391-402. Epub 1900 01 01.

GFRalpha1 expression in cells lacking RET is dispensable for organogenesis and nerve regeneration.

Enomoto H, Hughes I, Golden J, Baloh RH, Yonemura S, Heuckeroth RO, Johnson EM, Milbrandt J

Neuron.. 2004 November 1844 (4):623-36. Epub 1900 01 01.

Ratings & Reviews

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