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Daniel J. Lachant, D.O.

Daniel J. Lachant, D.O.

Pulmonary & Critical Care Medicine

UR Medicine Faculty The University of Rochester Medical Faculty Group (URMFG) consists of over 900 specialist and primary care providers spanning 19 departments. URMFG is certified by the National Committee for Quality Assurance.
Accountable Health Partner Accountable Health Partners (AHP) is a network of over 2,000 community and UR medical faculty and a dozen leading hospitals throughout the region. AHP offers a full range of care.
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About Me

I primarily treat patients with pulmonary hypertension, heart failure, and pulmonary embolus (blood clots in the lung). My goal is to improve and provide access to care for patients with pulmonary vascular disease across New York and central Pennsylvania. We are a nationally accredited PHA (Pulmon...
I primarily treat patients with pulmonary hypertension, heart failure, and pulmonary embolus (blood clots in the lung). My goal is to improve and provide access to care for patients with pulmonary vascular disease across New York and central Pennsylvania. We are a nationally accredited PHA (Pulmonary Hypertension Association) Comprehensive Care Center with an outpatient clinic and inpatient service at Strong Memorial Hospital. The URMC Pulmonary Hypertension group consists of my partner and mentor Jim White, MD,PhD; clinical/research nurse (Andrew Mintz); two research technicians (Deborah Haight and Jackie Bruno); a full time administrator (Monique Johnson); a research study coordinator (Michael Lachant) and a post-doctoral research associate (Allison Light PhD). We are involved with multiple pharmaceutical clinical trials, translational research, and laboratory research. Our pulmonary hypertension group has collaborated with the Pulmonary Hypertension Association to create a how to safely exercise videos series.

https://phassociation.org/patients/living-with-ph/exercise-and-ph/

https://phassociation.org/portfolio-items/exercise-and-pulmonary-rehab-in-ph/?portfolioCats=23550

Professional Background

I grew up in Ohio before moving to Philadelphia where I obtained my undergraduate degree (Biology) and was a collegiate rower at St. Joseph's University. I obtained my medical degree at the Philadelphia College Osteo Medicine. Afterwards I came to the University of Rochester for my internal medici...
I grew up in Ohio before moving to Philadelphia where I obtained my undergraduate degree (Biology) and was a collegiate rower at St. Joseph's University. I obtained my medical degree at the Philadelphia College Osteo Medicine. Afterwards I came to the University of Rochester for my internal medicine training and stayed for my Pulmonary and Critical Care fellowship. I am now apart of the URMC Pulmonary Hypertension group that is a nationally accredited PHA Comprehensive Care Center.

Certified Specialties

Critical Care Medicine - American Board of Internal Medicine

Internal Medicine - American Board of Internal Medicine

Pulmonary Disease - American Board of Internal Medicine

Faculty Appointments

Assistant Professor - Department of Medicine, Pulmonary Diseases and Critical Care (SMD)

Credentials

Residency & Fellowship

Fellowship, Pulmonary and Critical Care Medicine, University of Rochester Medical Center. 2014 - 2017

Residency, Internal Medicine, Strong Memorial Hospital/University of Rochester. 2012 - 2014

Internship, Internal Medicine, Strong Memorial Hospital/University of Rochester. 2011 - 2012

Education

DO | Philadelphia College of Osteopathic Medicine. 2011

Research

I have two areas of active research trying to personalize pulmonary vascular disease.

The first is using digital technology to measure changes in heart rate during the 6-minute walk test (submaximal exercise). We have found this measurement (Cardiac Effort) to be more reproducible than wal...
I have two areas of active research trying to personalize pulmonary vascular disease.

The first is using digital technology to measure changes in heart rate during the 6-minute walk test (submaximal exercise). We have found this measurement (Cardiac Effort) to be more reproducible than walk distance alone and correlates extremely well with right ventricular function. We are exploring other outcomes associated with this measurement. We are also looking at changes in actigraphy as a marker of treatment response. The other area of research is evaluating baseline and changes in vascular and coagulation parameters to better phenotype and characterize treatment strategies.

Publications

Journal Articles

Peak steps: Capacity for activity improves after adding approved therapy in pulmonary arterial hypertension.

Lachant D, Light A, Lachant M, Annis J, Hemnes A, Brittain E, James White R

Pulmonary circulation.. 2023 July 13 (3):e12285. Epub 09/10/2023.

Pulmonary Hypertension: How to Best Treat the Different Scleroderma Phenotypes?

Korman BD, Lachant DJ, Castelino FV

Rheumatic diseases clinics of North America.. 2023 May 49 (2):345-357. Epub 1900 01 01.

Cardiac Effort to Compare Clinic and Remote 6-Minute Walk Testing in PAH.

Lachant D, Kennedy E, Derenze B, Light A, Lachant M, White RJ

Chest.. 2022 June 28 Epub 06/28/2022.

Comparison of chest- and wrist-based actigraphy in pulmonary arterial hypertension.

Lachant D, Light A, Hannon K, Abbas F, Lachant M, White RJ

European heart journal. Digital health.. 2022 March 3 (1):90-97. Epub 11/02/2021.

Transitioning selexipag to oral treprostinil in patients with pulmonary artery hypertension.

Arevalo C, White RJ, Lachant D

Respiratory medicine case reports.. 2022 37 :101646. Epub 04/09/2022.

An Untapped Resource: Characteristics of Thrombus Recovered from Intermediate or High Risk Pulmonary Embolus Patients.

Newcomb G, Wilson BL, White RJ, Goldman B, Lachant NA, Lachant DJ

Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology.. 2021 October 27 :107392. Epub 10/27/2021.

Vasodilator use in precapillary pulmonary hypertension with end stage kidney disease: A single center experience.

Arevalo C, White RJ, Le T, Lachant D

Respiratory medicine.. 2021 September 4188 :106596. Epub 09/04/2021.

Resting heart rate as a surrogate for improvement in intermediate risk pulmonary embolus patients?

Roto D, Lachant NA, James White R, Lachant DJ

Respiratory medicine.. 2021 August 17187 :106578. Epub 08/17/2021.

Venous thromboembolism associates with SARS-CoV-2 more than seasonal influenza.

Lachant D, Roto D, Rappaport S, Prasad P, Lachant N, White RJ

Thrombosis research.. 2021 July 3205 :40-43. Epub 07/03/2021.

Evaluation of Clinical Recovery After Surgical Treatment for Hand Ischemia From Vasospastic and Occlusive Disease Using PROMIS.

Bernstein DN, Cliburn JA, Lachant DJ, White RJ, Hammert WC

Hand : official journal of the American Association for Hand Surgery.. 2021 March 31 :1558944721999727. Epub 03/31/2021.

Direct oral anticoagulant therapy in patients with morbid obesity after intermediate- or high-risk pulmonary emboli.

Lachant DJ, Bach C, Fe A, White RJ, Lachant NA

ERJ open research.. 2021 January 7 (1)Epub 02/01/2021.

Asymptomatic necrotizing myositis in a young male with progressive interstitial lung disease.

Baah S, Gorgone M, Lachant D

Respiratory medicine case reports.. 2021 32 :101374. Epub 03/02/2021.

Chronic therapeutic anticoagulation is associated with decreased thrombotic complications in SARS-CoV-2 infection.

Lachant DJ, Lachant NA, Kouides P, Rappaport S, Prasad P, White RJ

Journal of thrombosis and haemostasis : JTH.. 2020 October 18 (10):2640-2645. Epub 08/24/2020.

Combination treprostinil with sympathectomy and vascular reconstruction to treat recurrent digital ulcer disease.

Lemay M, Korman B, Hammert W, White RJ, Lachant D

Clinical and experimental rheumatology.. 2020 April 15 Epub 04/15/2020.

Selexipag Use in Clinical Practice: Mind the Gap.

White RJ, Lachant DJ

Chest.. 2020 April 157 (4):761-763. Epub 1900 01 01.

Clinical and imaging outcomes after intermediate- or high-risk pulmonary embolus.

Lachant D, Bach C, Wilson B, Chengazi V, Goldman B, Lachant N, Pietropaoli A, Cameron S, James White R

Pulmonary circulation.. 2020 10 (3):2045894020952019. Epub 09/21/2020.

Heart rate monitoring improves clinical assessment during 6-min walk.

Lachant DJ, Light A, Offen M, Adams J, White RJ

Pulmonary circulation.. 2020 10 (4):2045894020972572. Epub 12/09/2020.

Chronic thromboembolic pulmonary hypertension is a clot you cannot swat.

Bishop GJ, Gorski J, Lachant D, Cameron SJ

Journal of vascular surgery cases and innovative techniques.. 2019 December 5 (4):402-405. Epub 09/17/2019.

Heart Rate Expenditure Correlates with Right Ventricular Function.

Lachant DJ, Light AN, Mackin ML, Schwartz RG, White RJ

Annals of the American Thoracic Society.. 2019 November 4 Epub 11/04/2019.

Combination therapy improves vascular volume in female rats with pulmonary hypertension.

Lachant DJ, Meoli DF, Haight D, Staicu S, Akers S, Glickman S, Ambrosini R, Champion HC, White RJ

American journal of physiology. Lung cellular and molecular physiology.. 2019 October 1317 (4):L445-L455. Epub 07/19/2019.

CMV Encephalitis/Radiculitis: The Difficulty in Diagnosing in an Intubated Patient.

Newcomb G, Mariuz P, Lachant D

Case reports in critical care.. 2019 2019 :8067648. Epub 02/18/2019.

The clinical impact of pneumocystis and viral PCR testing on bronchoalveolar lavage in immunosuppressed patients.

Lachant DJ, Croft DP, McGrane Minton H, Hardy DJ, Prasad P, Kottmann RM

Respiratory medicine.. 2018 December 145 :35-40. Epub 10/22/2018.

Low dose monocrotaline causes a selective pulmonary vascular lesion in male and female pneumonectomized rats.

Lachant DJ, Meoli DF, Haight D, Lyons JA, Swarthout RF, White RJ

Experimental lung research.. 2018 February 44 (1):51-61. Epub 01/30/2018.

Nasopharyngeal viral PCR in immunosuppressed patients and its association with virus detection in bronchoalveolar lavage by PCR.

Lachant DJ, Croft DP, McGrane Minton H, Prasad P, Kottmann RM

Respirology : official journal of the Asian Pacific Society of Respirology.. 2017 August 22 (6):1205-1211. Epub 04/05/2017.

Legionella micdadei: A Forgotten Etiology of Growing Cavitary Nodules: A Case Report and Literature Review.

Lachant D, Prasad P

Case reports in pulmonology.. 2015 2015 :535012. Epub 09/15/2015.

Meningococcemia Presenting as a Myocardial Infarction.

Lachant D, Trawick D

Case reports in critical care.. 2015 2015 :953826. Epub 11/11/2015.

Novel oral anticoagulants after gastric bypass surgery: Caveat emptor

Lachant DJ, Uraizee I, Gupta R, Pedulla AJ.

International Journal of Case Reports and Images. 2013; 4(11): 663-665.

Methicillin Resistant Staphylococcus aureus Prostatic Abscess with Bacteremia.

Lachant DJ, Apostolakos M, Pietropaoli A

Case reports in infectious diseases. 2013 2013 :613961. Epub 12/24/2013.

Ratings & Reviews

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