Paulo Lizano, M.D., Ph.D.
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Paulo Lizano, M.D., Ph.D.
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At Beth Israel Deaconess Medical Center (BIDMC), Dr. Lizano led the ASPIRE Clinic, a program he helped build to support young adults experiencing early signs of psychosis. There, he and his team provide personalized treatment while also offering patients the opportunity to participate in cutting-edge research. His approach blends medical care with innovation, aiming to detect and treat mental illness as early—and as effectively—as possible.
Dr. Lizano is also a scientist. In his research, he studies how vision, the brain barrier system, inflammation, and neural circuits changes in the brain may play a role in psychiatric conditions. He uses brain scans, eye imaging, blood tests, neuromodulation, human stem cells, and other tools to better understand how these illnesses develop and how to treat them. He is especially interested in how early warning signs in the body can predict changes in thinking, emotions, or behavior—long before full symptoms appear.
A strong believer in collaboration, Dr. Lizano works with scientists, students, and healthcare providers to push the boundaries of what’s possible in psychiatry. He teaches at URMC and mentors future doctors and researchers, helping shape the next generation of leaders in mental health care.
At the heart of Dr. Lizano’s work is a simple, powerful idea: by combining science, compassion, and early intervention, we can improve lives—and change the future of mental health.
Certified Specialties
Psychiatry - American Board of Psychiatry & Neurology
Faculty Appointments
Interim Associate Professor - Department of Psychiatry, Research (SMD)
Connect with Paulo Lizano, M.D., Ph.D.
Credentials
Residency & Fellowship
Fellowship, Psychiatry & Neurology, Behavioral Neurology & Neuropsychiatry, Beth Israel Deaconess Medical Center. 2017 - 2019
Residency, Psychiatry, Beth Israel Deaconess Medical Center. 2013 - 2017
Education
MD | Rutgers New Jersey Medical School. 2013
PhD | Rutgers Biomedical & Health Sciences. 2011
Awards
Research Scholar Fellowship.
Outstanding Resident Award Program.
Outstanding Resident Teaching award.
Harry and Maida Solomon Award.
Research Colloquium.
Harry and Maida Solomon Award.
Joseph J. Schildkraut Award.
Daland Fellowship.
Robins-Guze awardee.
Faculty Award for Excellence in Teaching and Mentorship.
CAMS Award.
Research
Rese...
Research Focus
Microvascular and inflammatory biomarkers: Dr. Lizano has led pioneering efforts identifying vascular signatures—such as anti-angiogenic markers like sFlt-1 and VEGF polymorphisms—that predict gray matter loss, evolving psychopathology, and cognitive outcomes in schizophrenia and bipolar II depression.
Multimodal imaging and retinal oculomics: Combining retinal imaging, neuroimaging, and blood-based biomarkers, his lab aims to develop diagnostic and prognostic indicators for early-course psychosis.
Neuromodulation interventions: Dr. Lizano explores targeted noninvasive brain stimulation—such as tDCS and HD-tES—applied to brain regions linked to hallucinations, including the visual cortex and superior temporal sulcus.
Impact & Recognition
Published over 100 peer-reviewed articles, with a strong focus on psychotic disorders, retinal biomarkers, neurovascular pathology, and neuromodulation.
Recognized for receiving funding from major institutions including the NIMH, Burroughs Wellcome Fund, OneMind, Harvard Catalyst, and others.
Clinical and Mentorship Activities
Was the founder and clinical director of the BIDMC ASPIRE Clinic, an early psychosis intervention program offering integrated patient care and research participation for individuals aged ~19–45 with recent onset psychosis.
Heads the Lizano Translational Neuroscience Lab, which trains students and fellows in translational neuroscience applications and fosters projects across retinal and brain imaging, biomarkers, human iPSC models of disease, and neuromodulation.
Dr. Paulo Lizano is a leading figure in translational neuropsychiatry, blending rigorous imaging, molecular biomarkers, and neuromodulation to better understand and treat psychosis. His work especially emphasizes early detection and intervention in serious mental illness, with the goal of building clinically actionable tools for diagnosis and therapy.
Publications
Journal Articles
Demirlek C, Stiltner B, Velez-Perez E, Zeng V, Silverstein S, Aideyan B, Lizano P
medRxiv : the preprint server for health sciences.. 2025 August 21 Epub 08/21/2025.
Velez-Perez E, Demirlek C, Zeng V, Silverstein S, Aideyan B, Lizano P
medRxiv : the preprint server for health sciences.. 2025 August 21 Epub 08/21/2025.
Cao Y, Lizano P, Li M, Opel N, Sen ZD, Colic L, Sun H, Zhou X, Aruci M, Chand T, Long X, Deng G, Mu J, Guo S, Sun H, Gong Q, Qiu C, Walter M, Jia Z
Brain, behavior, and immunity.. 2025 August 128 :208-218. Epub 04/06/2025.
Liu D, Choi KW, Lizano P, Yuan W, Yu KH, Smoller J, Kohane I
Schizophrenia research.. 2025 July 7283 :59-66. Epub 07/07/2025.
Zhang L, Ivleva EI, Parker DA, Hill SK, Lizano PL, Keefe RSE, Keedy SK, McDowell JE, Pearlson GD, Clementz BA, Keshavan MS, Gershon ES, Tamminga CA, Sweeney JA, Bishop JR
The American journal of psychiatry.. 2025 May 28 :appiajp20240709. Epub 05/28/2025.
Türközer HB, Zeng V, Hoang D, Sritharan J, Iska N, Ivleva EI, Clementz BA, Pearlson GD, Keedy S, Gershon ES, Tamminga CA, Keshavan MS, Lizano P
medRxiv : the preprint server for health sciences.. 2025 February 13 Epub 02/13/2025.
Cao Y, Lizano P, Li M, Chand T, Sun H, Zhou X, Deng G, Long X, Mu J, Gong Q, Walter M, Qiu C, Jia Z
Journal of affective disorders.. 2025 January 1368 :493-502. Epub 09/17/2024.
Zhang Y, Lizano P
Harvard review of psychiatry.. 2025 33 (3):158-169. Epub 1900 01 01.
Sritharan J, Zeng V, Petr J, Mutsaerts HJ, Hoang D, Bolo NR, Ivleva EI, Dai W, Gershon ES, Keedy SK, Parker DA, Trotti RL, McDowell JE, Clementz BA, Tamminga CA, Pearlson GD, Keshavan MS, Lizano P
Frontiers in psychiatry.. 2025 16 :1566184. Epub 04/29/2025.
Raymond N, Trotti R, Lizano P
Frontiers in psychiatry.. 2025 16 :1568895. Epub 05/08/2025.
Molho W, Stiltner B, Raymond N, Kiely C, Trotti R, Harris C, Bannai D, Keshavan M, Silverstein S, Lizano P
Schizophrenia research.. 2024 December 274 :137-141. Epub 09/17/2024.
Lizano P, Velez-Perez E
Biological psychiatry.. 2024 November 1596 (10):769-771. Epub 1900 01 01.
Lizano P, Karmacharya R
Schizophrenia research.. 2024 November 273 :1-3. Epub 08/29/2024.
Rychagov N, Del Re EC, Zeng V, Oykhman E, Lizano P, McDowell J, Yassin W, Clementz BA, Gershon E, Pearlson G, Sweeney JA, Tamminga CA, Keshavan MS
Schizophrenia research.. 2024 September 271 :169-178. Epub 07/19/2024.
Raymond N, Trotti R, Oss E, Lizano P
Cortex; a journal devoted to the study of the nervous system and behavior.. 2024 September 178 :245-248. Epub 07/10/2024.
Sheehan N, Bannai D, Silverstein SM, Lizano P
Schizophrenia bulletin.. 2024 August 2750 (5):1067-1082. Epub 1900 01 01.
Xiao H, Cao Y, Lizano P, Li M, Sun H, Zhou X, Deng G, Li J, Chand T, Jia Z, Qiu C, Walter M
Brain, behavior, and immunity.. 2024 August 120 :44-53. Epub 05/21/2024.
Song SH, Cunningham TJ, Zhang Y, Lizano P, Keshavan MS
Asian journal of psychiatry.. 2024 August 98 :104070. Epub 05/13/2024.
Velez-Perez E, Raymond N, Kiely C, Molho W, Trotti R, Harris C, Bannai D, Hegde R, Herold S, Keshavan M, Silverstein S, Lizano P
Biomarkers in neuropsychiatry.. 2024 June 10 Epub 03/13/2024.
Cao Y, Sun H, Lizano P, Deng G, Zhou X, Xie H, Mu J, Long X, Xiao H, Liu S, Wu B, Gong Q, Qiu C, Jia Z
Psychological medicine.. 2024 March 54 (4):775-784. Epub 09/06/2023.
Bannai D, Reuter M, Hegde R, Hoang D, Adhan I, Gandu S, Pong S, Raymond N, Zeng V, Chung Y, He G, Sun D, van Erp TGM, Addington J, Bearden CE, Cadenhead K, Cornblatt B, Mathalon DH, McGlashan T, Jeffries C, Stone W, Tsuang M, Walker E, Woods SW, Cannon TD, Perkins D, Keshavan M, Lizano P
Brain, behavior, and immunity.. 2024 March 117 :70-79. Epub 12/31/2023.
Keshavan MS, Michael Song SH, Zhang Y, Lizano P
Asian journal of psychiatry.. 2024 February 92 :103869. Epub 12/14/2023.
Molho W, Raymond N, Reinhart RMG, Trotti R, Grover S, Keshavan M, Lizano P
Asian journal of psychiatry.. 2024 February 92 :103887. Epub 12/26/2023.
Kiely C, Douglas KAA, Douglas VP, Miller JB, Lizano P
Psychiatry research.. 2024 January 331 :115629. Epub 11/25/2023.
Bannai D, Cao Y, Keshavan M, Reuter M, Lizano P
Journal of visualized experiments : JoVE.. 2023 December 15 (202)Epub 12/15/2023.
Lizano P, Kiely C, Mijalkov M, Meda SA, Keedy SK, Hoang D, Zeng V, Lutz O, Pereira JB, Ivleva EI, Volpe G, Xu Y, Lee AM, Rubin LH, Kristian Hill S, Clementz BA, Tamminga CA, Pearlson GD, Sweeney JA, Gershon ES, Keshavan MS, Bishop JR
Brain, behavior, and immunity.. 2023 November 114 :3-15. Epub 07/26/2023.
Cao Y, Lizano P, Deng G, Sun H, Zhou X, Xie H, Zhan Y, Mu J, Long X, Xiao H, Liu S, Gong Q, Qiu C, Jia Z
Psychiatry and clinical neurosciences.. 2023 November 77 (11):613-621. Epub 09/08/2023.
Green JB, Rodriguez J, Keshavan M, Lizano P, Torous J
JMIR formative research.. 2023 October 37 :e46491. Epub 10/03/2023.
Raymond N, Reinhart RMG, Trotti R, Parker D, Grover S, Turkozer B, Sabatinelli D, Hegde R, Bannai D, Hoang D, Gandu S, Clementz B, Keshavan M, Lizano P
Asian journal of psychiatry.. 2023 October 88 :103750. Epub 08/22/2023.
Lizano P, Pong S, Santarriaga S, Bannai D, Karmacharya R
Molecular psychiatry.. 2023 September 28 (9):3698-3708. Epub 09/20/2023.
Zhang L, Lizano P, Xu Y, Rubin LH, Lee AM, Lencer R, Reilly JL, Keefe RSE, Keedy SK, Pearlson GD, Clementz BA, Keshavan MS, Gershon ES, Tamminga CA, Sweeney JA, Hill SK, Bishop JR
Schizophrenia research.. 2023 May 255 :69-78. Epub 03/23/2023.
Del Re EC, Yassin W, Zeng V, Keedy S, Alliey-Rodriguez N, Ivleva E, Hill S, Rychagov N, McDowell JE, Bishop JR, Mesholam-Gately R, Merola G, Lizano P, Gershon E, Pearlson G, Sweeney JA, Clementz B, Tamminga C, Keshavan M
Schizophrenia research.. 2023 May 255 :102-109. Epub 03/27/2023.
Senay O, Seethaler M, Makris N, Yeterian E, Rushmore J, Cho KIK, Rizzoni E, Heller C, Pasternak O, Szczepankiewicz F, Westin CF, Losak J, Ustohal L, Tomandl J, Vojtisek L, Kudlicka P, Kikinis Z, Holt D, Lewandowski KE, Lizano P, Keshavan MS, Öngür D, Kasparek T, Breier A, Shenton ME, Seitz-Holland J, Kubicki M
Human brain mapping.. 2023 April 1544 (6):2465-2478. Epub 02/06/2023.
Raymond N, Reinhart RMG, Trotti R, Parker D, Grover S, Turkozer B, Sabatinelli D, Hegde R, Bannai D, Gandu S, Clementz B, Keshavan M, Lizano P
medRxiv : the preprint server for health sciences.. 2023 April 3 Epub 04/03/2023.
Zeng R, Garg I, Bannai D, Kasetty M, Katz R, Park JY, Lizano P, Miller JB
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fu?r klinische und experimentelle Ophthalmologie.. 2022 November 260 (11):3505-3515. Epub 06/09/2022.
Türközer HB, Lizano P, Adhan I, Ivleva EI, Lutz O, Zeng V, Zeng A, Raymond N, Bannai D, Lee A, Bishop JR, Clementz BA, Pearlson GD, Sweeney JA, Gershon ES, Keshavan MS, Tamminga CA
Biological psychiatry.. 2022 September 192 (5):396-406. Epub 04/12/2022.
Bitanihirwe BKY, Lizano P, Woo TW
Molecular psychiatry.. 2022 September 27 (9):3573-3582. Epub 05/26/2022.
Zhang L, Lizano P, Guo B, Xu Y, Rubin LH, Hill SK, Alliey-Rodriguez N, Lee AM, Wu B, Keedy SK, Tamminga CA, Pearlson GD, Clementz BA, Keshavan MS, Gershon ES, Sweeney JA, Bishop JR
Brain, behavior, & immunity - health.. 2022 July 22 :100459. Epub 04/08/2022.
Zhang L, Hill SK, Guo B, Wu B, Alliey-Rodriguez N, Eum S, Lizano P, Ivleva EI, Reilly JL, Keefe RSE, Keedy SK, Tamminga CA, Pearlson GD, Clementz BA, Keshavan MS, Gershon ES, Sweeney JA, Bishop JR
Progress in neuro-psychopharmacology & biological psychiatry.. 2022 March 8113 :110464. Epub 10/29/2021.
Hoang D, Xu Y, Lutz O, Bannai D, Zeng V, Bishop JR, Keshavan M, Lizano P
Brain, behavior, and immunity.. 2022 February 100 :297-308. Epub 12/04/2021.
Bannai D, Adhan I, Katz R, Kim LA, Keshavan M, Miller JB, Lizano P
Schizophrenia bulletin.. 2022 January 2148 (1):80-89. Epub 1900 01 01.
Lai M, Hegde R, Kelly S, Bannai D, Lizano P, Stickgold R, Manoach DS, Keshavan M
Psychiatry research.. 2022 January 307 :114265. Epub 11/13/2021.
Bishop JR, Zhang L, Lizano P
Harvard review of psychiatry.. 2022 30 (1):59-70. Epub 1900 01 01.
Ward HB, Brady RO, Halko MA, Lizano P
Frontiers in psychiatry.. 2022 13 :824878. Epub 02/09/2022.
Raymond N, Reinhart RMG, Keshavan M, Lizano P
Harvard review of psychiatry.. 2022 30 (3):181-190. Epub 1900 01 01.
Li CY, Garg I, Bannai D, Kasetty M, Katz R, Adhan I, Douglas KAA, Wang JC, Kim LA, Keshavan M, Lizano P, Miller JB
Clinical ophthalmology.. 2022 16 :2363-2371. Epub 07/28/2022.
Johnson MC, Baum ML, Lizano P
Schizophrenia research.. 2021 December 238 :185-187. Epub 11/03/2021.
Lizano P, Lutz O, Xu Y, Rubin LH, Paskowitz L, Lee AM, Eum S, Keedy SK, Hill SK, Reilly JL, Wu B, Tamminga CA, Clementz BA, Pearlson GD, Gershon ES, Keshavan MS, Sweeney JA, Bishop JR
Molecular psychiatry.. 2021 July 26 (7):3430-3443. Epub 10/15/2020.
Grover S, Keshavan MS, Lizano PL, Reinhart RMG
Schizophrenia research.. 2021 July 233 :114-115. Epub 07/26/2021.
Hoang D, Lizano P, Lutz O, Zeng V, Raymond N, Miewald J, Montrose D, Keshavan M
Psychiatry research. Neuroimaging.. 2021 March 30309 :111249. Epub 01/08/2021.
Zeng V, Lizano P, Bolo NR, Lutz O, Brady R, Ivleva EI, Dai W, Clementz B, Tamminga C, Pearlson G, Keshavan M
Bipolar disorders.. 2021 March 23 (2):130-140. Epub 07/25/2020.
Kelly S, Guimond S, Pasternak O, Lutz O, Lizano P, Cetin-Karayumak S, Sweeney JA, Pearlson G, Clementz BA, McDowell JE, Tamminga CA, Shenton ME, Keshavan MS
Psychiatry research. Neuroimaging.. 2021 February 28308 :111234. Epub 12/16/2020.
Tamminga CA, Clementz BA, Pearlson G, Keshavan M, Gershon ES, Ivleva EI, McDowell J, Meda SA, Keedy S, Calhoun VD, Lizano P, Bishop JR, Hudgens-Haney M, Alliey-Rodriguez N, Asif H, Gibbons R
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology.. 2021 January 46 (1):143-155. Epub 09/26/2020.
Pong S, Lizano P, Karmacharya R
Journal of visualized experiments : JoVE.. 2020 November 19 (165)Epub 11/19/2020.
Bannai D, Lutz O, Lizano P
Schizophrenia research.. 2020 October 224 :19-21. Epub 07/27/2020.
Lizano P, Dhaliwal K, Lutz O, Mothi SS, Miewald J, Montrose D, Keshavan M
Psychological medicine.. 2020 September 50 (12):2057-2065. Epub 08/27/2019.
Lutz O, Lizano P, Mothi SS, Zeng V, Hegde RR, Hoang DT, Henson P, Brady R, Tamminga CA, Pearlson G, Clementz BA, Sweeney JA, Keshavan MS
Schizophrenia research.. 2020 September 223 :96-104. Epub 06/02/2020.
Bannai D, Lizano P
Schizophrenia research.. 2020 June 220 :25-26. Epub 04/01/2020.
Adhan I, Lizano P, Bannai D, Lutz O, Dhaliwal K, Zeng V, Miewald J, Montrose D, Keshavan M
Psychiatry research.. 2020 June 288 :112957. Epub 04/16/2020.
Bannai D, Lizano P, Kasetty M, Lutz O, Zeng V, Sarvode S, Kim LA, Hill S, Tamminga C, Clementz B, Gershon E, Pearlson G, Miller JB, Keshavan M
Psychiatry research. Neuroimaging.. 2020 May 30299 :111061. Epub 02/29/2020.
Keshavan MS, Collin G, Guimond S, Kelly S, Prasad KM, Lizano P
Neuroimaging clinics of North America.. 2020 February 30 (1):73-83. Epub 11/11/2019.
Keshavan M, Lizano P, Prasad K
World psychiatry : official journal of the World Psychiatric Association (WPA).. 2020 February 19 (1):110-111. Epub 1900 01 01.
Lizano P, Bannai D, Lutz O, Kim LA, Miller J, Keshavan M
Schizophrenia bulletin.. 2020 January 446 (1):43-53. Epub 1900 01 01.
Adhan I, Bannai D, Lizano P
Schizophrenia research.. 2020 January 215 :3-5. Epub 10/23/2019.
Burke MJ, Lizano P, Jacobs C, Stern TA
Psychosomatics.. 2020 61 (1):81-85. Epub 03/22/2019.
Lizano P, Lutz O, Ling G, Lee AM, Eum S, Bishop JR, Kelly S, Pasternak O, Clementz B, Pearlson G, Sweeney JA, Gershon E, Tamminga C, Keshavan M
The American journal of psychiatry.. 2019 July 1176 (7):564-572. Epub 06/05/2019.
Lutz O, Lizano P, Mothi SS, Joseph A, Tandon N, Ormston L, Hooper S, Keshavan M, Shashi V
Psychiatry research. Neuroimaging.. 2019 March 30285 :47-50. Epub 01/31/2019.
Lizano P, Prasad KM, Keshavan MS
Schizophrenia research.. 2019 February 204 :4-6. Epub 01/15/2019.
Lizano P, Lutz O, Ling G, Padmanabhan J, Tandon N, Sweeney J, Tamminga C, Pearlson G, Ruaño G, Kocherla M, Windemuth A, Clementz B, Gershon E, Keshavan M
Translational psychiatry.. 2018 October 118 (1):215. Epub 10/11/2018.
Hill K, Bolo N, Sarvode Mothi S, Lizano P, Guimond S, Tandon N, Molokotos E, Keshavan M
Psychiatry research. Neuroimaging.. 2017 September 30267 :36-44. Epub 07/14/2017.
Lizano PL, Yao JK, Tandon N, Mothi SS, Montrose DM, Keshavan MS
Schizophrenia research.. 2017 May 183 :75-81. Epub 11/15/2016.
Lizano P, Rashed E, Stoll S, Zhou N, Wen H, Hays TT, Qin G, Xie LH, Depre C, Qiu H
Scientific reports.. 2017 April 207 :46324. Epub 04/20/2017.
Lizano PL, Keshavan MS, Tandon N, Mathew IT, Mothi SS, Montrose DM, Yao JK
Schizophrenia research.. 2016 January 170 (1):115-22. Epub 12/11/2015.
Lizano P, Popat-Jain A, Scharf JM, Berman NC, Widge A, Dougherty DD, Eskandar E
Harvard review of psychiatry.. 2016 24 (4):294-301. Epub 1900 01 01.
Rashed E, Lizano P, Dai H, Thomas A, Suzuki CK, Depre C, Qiu H
PloS one.. 2015 10 (3):e0119537. Epub 03/06/2015.
Haller CS, Padmanabhan JL, Lizano P, Torous J, Keshavan M
F1000prime reports. 2014 6 :57. Epub 07/08/2014.
Lizano P, Rashed E, Kang H, Dai H, Sui X, Yan L, Qiu H, Depre C
Cardiovascular research.. 2013 September 199 (4):685-93. Epub 06/04/2013.
Laure L, Long R, Lizano P, Zini R, Berdeaux A, Depre C, Morin D
Free radical biology & medicine.. 2012 52 (11-12):2168-76. Epub 04/18/2012.
Qiu H, Lizano P, Laure L, Sui X, Rashed E, Park JY, Hong C, Gao S, Holle E, Morin D, Dhar SK, Wagner T, Berdeaux A, Tian B, Vatner SF, Depre C
Circulation.. 2011 July 26124 (4):406-15. Epub 07/11/2011.
Chen L, Lizano P, Zhao X, Sui X, Dhar SK, Shen YT, Vatner DE, Vatner SF, Depre C
American journal of physiology. Heart and circulatory physiology.. 2011 April 300 (4):H1303-10. Epub 02/11/2011.
Hedhli N, Lizano P, Hong C, Fritzky LF, Dhar SK, Liu H, Tian Y, Gao S, Madura K, Vatner SF, Depre C
American journal of physiology. Heart and circulatory physiology.. 2008 October 295 (4):H1385-93. Epub 08/01/2008.
Garay E, Jankowski P, Lizano P, Marczak S, Maehr H, Adorini L, Uskokovic MR, Studzinski GP
Bioorganic & medicinal chemistry.. 2007 July 115 (13):4444-55. Epub 04/25/2007.
Books
Textbook of Schizophrenia (2019)
Authors: Causes of Schizophrenia
Publisher: American Psychiatric Publishing 2019
Early Intervention in psychiatric Disorders Across Cultures (2017)
Chapter: Brain changes in the early course of schizophrenia
Authors: Keshavan M, Lizano P, Padmanabhan J.
Publisher: Oxford University Press 2017
Ratings & Comments
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