Jennifer H. Anolik, M.D., Ph.D.

Jennifer H. Anolik, M.D., Ph.D.

Contact Information

University of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 695
Rochester, NY 14642

Office: () -
Fax: (585) 442-3214
Administrative: () -
Lab: (585) 273-2179

Lab Information

Her lab focuses on the investigation of B cell tolerance, B cell development and the effects of therapy in lupus, and the development of a murine model of B cell depletion.

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Research Bio

Dr. Anolik's research interests include the role of B cells in the pathophysiology of human systemic lupus and the study of new immuno-modulatory treatments for lupus. As part of the research group at the University of Rochester she has been one of the pioneers in the use of B-cell depletion for the therapy of autoimmune diseases and investigation of the effects of B cell depletion on immune function in SLE patients. She has also pioneered the use of tonsil biopsy as a means of probing immune dysregulation in autoimmune diseases, including SLE and RA.

Awards & Honors (National)

American Society for Clinical Investigation 2015
Eisenberg Memorial Lupus Lectureship | University of MO-Columbia | Columbia, MO 2008
Edmund Dubois Memorial Lectureship Award | American College of Rheumatology 2005
Rheumatology Fellow Award | American College of Rheumatology 2001
Medical Scientist Training Program Scholarship | NIH | University of Rochester 1994 - 1996
Medical Scientist Training Program Scholarship | NIH | University of Rochester 1988 - 1990

Awards & Honors (Local)

Lawrence Kohn Senior Teaching Fellow 2006 - 2008
Buswell Fellowship | University of Rochester Dept of Medicine | Rochester, NY 2003
NIH Training Grant T32-AI07169-16 | University of Rochester | Rochester, NY 2000 - 2002
Stuber Fellowship | University of Rochester | Rochester, NY 1999 - 2000
Raphael Dolin Resident Research Award | University of Rochester | Rochester, NY 1999
Stotz Fellowship | University of Rochester Biochemisty Dept | Rochester, NY 1991 - 1992
Phi Beta Kappa | Swathmore College 1988
Sigma Xi Scientific Research Society | Swathmore College 1988
Outstanding Senior Chemistry Student Award | American Institutue ofChemists | Swathmore College 1988
Dean's Letter of Recognition | University of Rochester | Rochester, NY 1988 - 1989
Summer Research Fellowship | Dana Foundation | Swathmore College 1987

Recent Journal Articles

Showing the 5 most recent journal articles. 65 available »

2016 Apr
Meednu N, Zhang H, Owen T, Sun W, Wang V, Cistrone C, Rangel-Moreno J, Xing L, Med B, Anolik JH. "Production of RANKL by Memory B Cells: A Link Between B Cells and Bone Erosion in Rheumatoid Arthritis." Arthritis & rheumatology. 2016 Apr; 68(4):805-16.
2015 Sep
Bird AK, Meednu N, Anolik JH. "New insights into B cell biology in systemic lupus erythematosus and Sjögren's syndrome." Current opinion in rheumatology. 2015 Sep; 27(5):461-7.
Adlowitz DG, Barnard J, Biear JN, Cistrone C, Owen T, Wang W, Palanichamy A, Ezealah E, Campbell D, Wei C, Looney RJ, Sanz I, Anolik JH. "Expansion of Activated Peripheral Blood Memory B Cells in Rheumatoid Arthritis, Impact of B Cell Depletion Therapy, and Biomarkers of Response." PloS one. 2015 10(6):e0128269. Epub 2015 Jun 05.
2014 Jul
Zhang H, Hilton MJ, Anolik JH, Welle SL, Zhao C, Yao Z, Li X, Wang Z, Boyce BF, Xing L. "NOTCH inhibits osteoblast formation in inflammatory arthritis via noncanonical NF-?B." The Journal of clinical investigation. 2014 Jul; 124(7):3200-14. Epub 2014 Jun 02.
2014 Apr 1
Wang W, Rangel-Moreno J, Owen T, Barnard J, Nevarez S, Ichikawa HT, Anolik JH. "Long-term B cell depletion in murine lupus eliminates autoantibody-secreting cells and is associated with alterations in the kidney plasma cell niche." The Journal of immunology : official journal of the American Association of Immunologists. 2014 Apr 1; 192(7):3011-20. Epub 2014 Feb 26.

Current Appointments

Associate Professor - Department of Medicine, Allergy/Immunology and Rheumatology (SMD) - Primary
Associate Professor - Department of Microbiology and Immunology (SMD)
Associate Professor - Department of Pathology and Laboratory Medicine (SMD)


Internal Medicine - American Board of Internal Medicine
Rheumatology - American Board of Internal Medicine


MD | Medicine | Univ Rochester Sch Med/Dent1996
PhD | Biochemistry | Univ Rochester Sch Med/Dent1994
BA | Chemistry | Swarthmore College1988

Post-Doctoral Training & Residency

Fellowship in Rheumatology at University of Rochester Medical Center07/01/1999 - 06/30/2001
Residency in Internal Medicine at University of Rochester Medical Center07/01/1997 - 06/30/1999
Internship in Internal Medicine at University of Rochester Medical Center07/01/1996 - 06/30/1997