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Brian James Blyth, M.D.

Contact Information

Phone Numbers

Office: (585) 275-1198

URMFGA member of the University of Rochester Medical Faculty Group

groupAn Accountable Health Partner

assignmentNot Accepting New Patients

Patient Care Setting

Emergency Medicine


Professional Background

Dr. Blyth is currently a Associate Professor of Clinical Emergency Medicine.


The research efforts of the Blyth laboratory focus on traumatic brain injury. The overarching goal of our laboratory is to reduce the morbidity and mortality associated with traumatic brain injury. To accomplish this goal we rely on a translational approach: both clinical and basic studies are used to identify and solve relevant research questions that might lead to improved therapeutics for this disease. Ultimately, promising therapies are tested for efficacy through clinical trials. Laboratory resources include a repository of patient samples collected through a multicenter research network that includes six medical centers located throughout upstate New York with 300,000 patient visits per year. Data and clinical samples collected through this network are housed at a central repository located within the laboratory. Physically, the laboratory consists of state of the art bench research facilities within the Center for Neural Development and Disease at the University of Rochester Medical Center. We utilize patient based studies as well as cell culture and animal models of disease. Several mouse and rat models of traumatic brain injury are utilized. Relevant questions are identified through studies of large numbers of human patients and examined in detail in animal models. Mechanistic insights gleaned through this approach may then allow for novel therapeutics that can then be developed for clinical trials.



  • Emergency Medicine - American Board of Emergency Medicine


MD | University of Pittsburgh

Post-doctoral Training & Residency

07/01/2000 - 06/30/2002
Residency in Emergency Medicine at University of Rochester Medical Center

07/01/1999 - 06/01/2000
Internship in Emergency Medicine at University of Rochester Medical Center


2008 - 2008
Army Commendation Medal   
Sponsor: US Army
Location: Bagram Air Field, Afghanistan

Army Commendation Medal   
Sponsor: US Army
Location: Fort Lewis, Washington

The Course in Scientific Management
Sponsor: The Burroughs Welcome Fund and Howard Hughes Medical Institute

Emergency Medicine Faculty Teaching Award
Sponsor: University of Rochester Medical Center

Army Commendation Medal   
Sponsor: US Army
Location: Doha, Kuwait

Emergency Medicine Resident Teaching Award
Sponsor: University of Rochester Medical Center
Location: Rochester, NY

Excellence in Emergency Medicine Award for Graduating Medical Students
Sponsor: Society for Academic Emergency Medicine

1997 - 1998
Howard Hughes Medical Institute Fellowship Award
Location: University of Pittsburgh Medical Center

University of Rochester Medical Center Departmental Research Fellow 2002-2003 Department of Emergency Medicine Rochester, NY

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Journal Articles

Kiechle K, Bazarian JJ, Merchant-Borna K, Stoecklein V, Rozen E, Blyth B, Huang JH, Dayawansa S, Kanz K, Biberthaler P. "Subject-specific increases in serum S-100B distinguish sports-related concussion from sports-related exertion." PloS one.. 2014 9(1):e84977. Epub 2014 Jan 08.

Bazarian JJ, Blyth B, He H, Mookerjee S, Jones C, Kiechle K, Moynihan R, Wojcik S, Grant WD, Secreti L, Triner W, Moscati R, Leinhart A, Ellis G, Khan J. "Classification accuracy of serum Apo A-I and S100B for the diagnosis of mild traumatic brain injury and prediction of abnormal initial head computed tomography scan." Journal of neurotrauma.. 2013 Oct 15; 30(20):1747-54. Epub 2013 Aug 24.

Blyth B, Farahvar A, He H, Nayak A, Yang C, Shaw G, Bazarian JJ. "Elevated serum ubiquitin carboxy-terminal hydrolase L1 is associated with abnormal blood-brain barrier function after traumatic brain injury." Journal of neurotrauma.. 2011 Dec 0; 28(12):2453-62. Epub 2011 Aug 08.