Skip to main content
Explore URMC

Anthony P. Pietropaoli, M.D.

Contact Information

Phone Numbers

Office: (585) 275-4861

Fax: (585) 273-1058

URMFGA member of the University of Rochester Medical Faculty Group

groupAn Accountable Health Partner

assignmentAccepting New Patients

Research Labs

Faculty Appointments

Patient Care Setting



Professional Background

Dr. Anthony Pietropaoli was born and raised in Rochester, NY. He graduated from the College of the Holy Cross ith a B.A. degree, majoring in English & Pre-medical studies. He attended Upstate Medical University and then moved to Pittsburgh for internship, residency, and chief residency in Internal Medicine. Dr. Pietropaoli spent two years practicing General Internal Medicine before making the decision to specialize in Pulmonary & Critic al Care Medicine. He completed this fellowship at the University of Rochester in 1999, joining the faculty thereafter. He has served a number of roles in the division and medical center, currently directing the Medical Intensive Care Unit, the Respiratory Therapy Department, and the Pulmonary Rehabilitation Program. His clinical interests broad, but he spends most of his clinical time on all things critical care, pleural disease, and pulmonary rehabilitation.


Dr. Pietropaoli developed and leads a critical care translational research program at the University of Rochester. During this time we have enrolled over 500 critically ill patients and volunteers in our cohort studies, made new observations about the relationships between NO metabolism, red blood cell dysfunction, neutrophil dysfunction, vascular function, and clinical outcomes, and forged strong collaborations with clinical and basic science investigators across a number of university departments.

Dr. Pietropaoli also collaborates with investigators in laboratory and transfusion medicine investigating the "storage lesion" that develops in banked blood and clinical outcomes in critically ill transfusion recipients.

Dr. Pietropaoli also investigates the epidemiology of critical care medicine. He is the UR principal investigator for the Critical Illness Outcomes Study, a nationwide cohort study involving over 6,000 patients in 69 U.S. ICUs designed to examine relationships between patient characteristics, ICU characteristics, and mortality

Dr. Pietropaoli's long-term goal is to nurture the growth and productivity of this comprehensive, multidisciplinary critical care research program, promoting new discoveries that improve outcomes for our critically ill population.



  • Critical Care Medicine - American Board of Internal Medicine
  • Internal Medicine - American Board of Internal Medicine
  • Pulmonary Disease - American Board of Internal Medicine


MD | SUNY Health Science Center at Syracuse

Post-doctoral Training & Residency

07/01/1996 - 06/30/1999
Fellowship in Pulmonary/Critical Care at University of Rochester Medical Center

06/01/1991 - 07/01/1994
Residency in Internal Medicine at University of Pittsburgh Medical Center

06/24/1990 - 05/31/1991
Internship in Internal Medicine at University of Pittsburgh Medical Center

VIEW ALL expand_more


Highland Medicine Teaching Award
Sponsor: For contributions to residency education at Highland Hospital

Arthur W. Bauman Teaching Award (for outstanding educational contributions to the Internal Medicine Residency Program)

2005 - 2007
Lawrence A. Kohn Senior Teaching Fellow Award
Sponsor: University of Rochester, Department of Medicine

2003 - Present
Best Doctors in America
Sponsor: America's Best Doctors

2003 - 2005
America's Top Physicians
Sponsor: Consumer Research Council of America

Arthur W. Bauman Teaching Award (for outstanding educational contributions to the Internal Medicine Residency Program)
Sponsor: University of Rochester, Department of Medicine

2001 - Present
Fellow, American College of Chest Physicians

Young Leaders in Pulmonary Medicine
Sponsor: Boehringer Ingelheim Pharmaceuticals
Location: San Antonio, Texas

Selected participant, Symposium on Leadership Development in Pulmonary & Critical Care Medicine
Sponsor: American College of Chest Physicians
Location: Philadephia, PA

1990 - Present
Alpha Omega Alpha Medical Honor Society

VIEW ALL expand_more


Journal Articles

Trzeciak A, Pietropaoli AP, Kim M. "Biomarkers and Associated Immune Mechanisms for Early Detection and Therapeutic Management of Sepsis." Immune network.. 2020 Jun 0; 20(3):e23. Epub 2020 Jun 22.

Pietropaoli AP, Henrichs KF, Cholette JM, Spinelli SL, Phipps RP, Refaai MA, Blumberg N. "Total plasma heme concentration increases after red blood cell transfusion and predicts mortality in critically ill medical patients." Transfusion.. 2019 Feb 27; Epub 2019 Feb 27.

Cholette JM, Pietropaoli AP, Henrichs KF, Alfieris GM, Powers KS, Gensini F, Rubenstein JS, Sweeney D, Phipps R, Spinelli SL, Refaai MA, Eaton MP, Blumberg N. "Elevated free hemoglobin and decreased haptoglobin levels are associated with adverse clinical outcomes, unfavorable physiologic measures, and altered inflammatory markers in pediatric cardiac surgery patients." Transfusion.. 2018 Jul 0; 58(7):1631-1639. Epub 2018 Mar 30.

Books & Chapters

Chapter Title: "Human Clinical Studies of Airborne Pollutants"
Book Title: Toxicology of the Lung
Author List: Frampton, MW, Pietropaoli, AP, Morrow, PE, Utell, MJ
Edited By: Gardner, DE
Published By: CRC Press, Taylor & Francis Group 2005 in Boca Raton

Chapter Title: "Gender Differences in the Sepsis Syndrome: Clinical Evidence and Potential Mechanisms"
Book Title: Principles of Gender Specific Medicine
Author List: Pietropaoli, AP
Edited By: Marianne Legato
Published By: Elsevier Academic Press 2004 in San Diego

Chapter Title: "Approach to Mechanical Ventilation"
Book Title: The ICU Manual
Author List: Pietropaoli, AP
Edited By: Apostolakos, MJ, Papadakos, PJ
Published By: McGraw-HIll 2001 in New York