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Webster H. Pilcher, M.D., Ph.D.


Showing all 71 journal articles & 9 books available

Journal Articles

Pilcher W, Thomas BE, Bhasin SS, Jayasinghe RG, Yao L, Gonzalez-Kozlova E, Dasari S, Kim-Schulze S, Rahman A, Patton J, Fiala M, Cheloni G, Kourelis T, Dhodapkar MV, Vij R, Mehr S, Hamilton M, Cho HJ, Auclair D, Avigan DE, Kumar SK, Gnjatic S, Ding L, Bhasin M. "Cross center single-cell RNA sequencing study of the immune microenvironment in rapid progressing multiple myeloma." NPJ genomic medicine.. 2023 Jan 26; 8(1):3. Epub 2023 Jan 26.

Ellens NR, Schartz D, Rahmani R, Akkipeddi SMK, Kelly AG, Benesch CG, Parker SA, Burgett JL, Proper D, Pilcher WH, Mattingly TK, Grotta JC, Bhalla T, Bender MT. "Mobile Stroke Unit Operational Metrics: Institutional Experience, Systematic Review and Meta-Analysis." Frontiers in neurology. 2022 13:868051. Epub 2022 May 09.

Bender MT, Mattingly TK, Rahmani R, Proper D, Burnett WA, Burgett JL, LEsperance J, Cushman JT, Pilcher WH, Benesch CG, Kelly AG, Bhalla T. "Mobile stroke care expedites intravenous thrombolysis and endovascular thrombectomy." Stroke and vascular neurology.. 2021 Dec 24; Epub 2021 Dec 24.

Belkhir JR, Fitch WT, Garcea FE, Chernoff BL, Sims MH, Navarrete E, Haber S, Paul DA, Smith SO, Pilcher WH, Mahon BZ. "Direct electrical stimulation evidence for a dorsal motor area with control of the larynx." Brain stimulation.. 2020 Nov 17; Epub 2020 Nov 17.

Nair DR, Laxer KD, Weber PB, Murro AM, Park YD, Barkley GL, Smith BJ, Gwinn RP, Doherty MJ, Noe KH, Zimmerman RS, Bergey GK, Anderson WS, Heck C, Liu CY, Lee RW, Sadler T, Duckrow RB, Hirsch LJ, Wharen RE, Tatum W, Srinivasan S, McKhann GM, Agostini MA, Alexopoulos AV, Jobst BC, Roberts DW, Salanova V, Witt TC, Cash SS, Cole AJ, Worrell GA, Lundstrom BN, Edwards JC, Halford JJ, Spencer DC, Ernst L, Skidmore CT, Sperling MR, Miller I, Geller EB, Berg MJ, Fessler AJ, Rutecki P, Goldman AM, Mizrahi EM, Gross RE, Shields DC, Schwartz TH, Labar DR, Fountain NB, Elias WJ, Olejniczak PW, Villemarette-Pittman NR, Eisenschenk S, Roper SN, Boggs JG, Courtney TA, Sun FT, Seale CG, Miller KL, Skarpaas TL, Morrell MJ. "Nine-year prospective efficacy and safety of brain-responsive neurostimulation for focal epilepsy." Neurology.. 2020 Jul 20; Epub 2020 Jul 20.

Larson AS, Haines SJ, Pilcher WH, Piva TE, Grande AW. "From the historical examples of Drs. Osler, Cushing and Van Wagenen: Lessons on the importance of mentorship in contemporary neurosurgery." World neurosurgery.. 2020 May 17; Epub 2020 May 17.

Chernoff BL, Teghipco A, Garcea FE, Belkhir R, Sims MH, Paul DA, Tivarus ME, Smith SO, Hintz E, Pilcher WH, Mahon BZ. "Reorganized language network connectivity after left arcuate fasciculus resection: A case study." Cortex; a journal devoted to the study of the nervous system and behavior.. 2019 Nov 5; 123:173-184. Epub 2019 Nov 05.

Mahon BZ, Mead JA, Chernoff BL, Sims MH, Garcea FE, Prentiss E, Belkhir R, Haber SJ, Gannon SB, Erickson S, Wright KA, Schmidt MZ, Paulzak A, Milano VC, Paul DA, Foxx K, Tivarus M, Nadler JW, Behr JM, Smith SO, Li YM, Walter K, Pilcher WH. "Translational Brain Mapping at the University of Rochester Medical Center: Preserving the Mind Through Personalized Brain Mapping." Journal of visualized experiments : JoVE.. 2019 Aug 12; (150)Epub 2019 Aug 12.

Garcea FE, Almeida J, Sims MH, Nunno A, Meyers SP, Li YM, Walter K, Pilcher WH, Mahon BZ. "Domain-Specific Diaschisis: Lesions to Parietal Action Areas Modulate Neural Responses to Tools in the Ventral Stream." Cerebral cortex.. 2019 Jul 5; Epub 2018 Aug 28.

Pieters TA, Li YI, Towner JE, Schmidt T, Vates GE, Pilcher W, Li YM. "Comparative analysis of decompression versus decompression and fusion for surgical management of lumbar spondylolisthesis." World neurosurgery.. 2019 Feb 19; Epub 2019 Feb 19.

Chernoff BL, Sims MH, Smith SO, Pilcher WH, Mahon BZ. "Direct electrical stimulation of the left frontal aslant tract disrupts sentence planning without affecting articulation." Cognitive neuropsychology.. 2019 36(3-4):178-192. Epub 2019 Jun 18.

Mahon BZ, Miozzo M, Pilcher WH. "Direct electrical stimulation mapping of cognitive functions in the human brain." Cognitive neuropsychology.. 2019 36(3-4):97-102.

Chernoff BL, Teghipco A, Garcea FE, Sims MH, Paul DA, Tivarus ME, Smith SO, Pilcher WH, Mahon BZ. "A Role for the Frontal Aslant Tract in Speech Planning: A Neurosurgical Case Study." Journal of cognitive neuroscience.. 2018 May; 30(5):752-769. Epub 2018 Mar 23.

Schmidt TM, DeAndrea-Lazarus IA, Kimmell KT, Vates GE, Haines SJ, Pilcher WH. "For the further training of individuals in neurosurgery: a history of the William P. Van Wagenen Fellowship." Journal of neurosurgery.. 2018 Apr 27; :1-5. Epub 2018 Apr 27.

Garcea FE, Chernoff BL, Diamond B, Lewis W, Sims MH, Tomlinson SB, Teghipco A, Belkhir R, Gannon SB, Erickson S, Smith SO, Stone J, Liu L, Tollefson T, Langfitt J, Marvin E, Pilcher WH, Mahon BZ. "Direct Electrical Stimulation in the Human Brain Disrupts Melody Processing." Current biology : CB.. 2017 Sep 11; 27(17):2684-2691.e7. Epub 2017 Aug 24.

Markman JD, Gewandter JS, Frazer ME, Murray NM, Rast SA, McDermott MP, Chowdhry AK, Tompkinson E, Pilcher WH, Walter KA, Dworkin RH. "A Randomized, Double-blind, Placebo-Controlled Crossover Trial of Oxymorphone Hydrochloride and Propoxyphene/Acetaminophen Combination for the Treatment of Neurogenic Claudication Associated With Lumbar Spinal Stenosis." Spine.. 2015 May 15; 40(10):684-91.

Markman JD, Frazer ME, Rast SA, McDermott MP, Gewandter JS, Chowdhry AK, Czerniecka K, Pilcher WH, Simon LS, Dworkin RH. "Double-blind, randomized, controlled, crossover trial of pregabalin for neurogenic claudication." Neurology.. 2015 Jan 20; 84(3):265-72. Epub 2014 Dec 10.

Markman, J.D., J.S. Gewandter, M. E. Frazer, N. M. Murray, S.A. Rast, M. P. McDermott, A.K. Chowdhry, E. Tompkinson, W.H. Pilcher, K. A. Walter, R. H. Dworkin. "A Randomized, Double-Blind, Placebo-Controlled Cross-over Trial of Oxymorphone Hydrochloride and Propoxyphene/acetaminophen combination for the Treatment of Neurogenic Claudication Associated with Lumbar Spinal Stenosis". Spine. 2015; .

Markman, J. D.; M. E. Frazer; S. A. Rast; M. P. McDermott; J. S. Gewandter; K. Chowdhry; K. Czerniecka; W. H. Pilcher; L. S. Simon; R. H. Dworkin. "Double-blind, randomized, controlled, crossover trial of pregabalin for neurogenic claudication". Neurology. 2015; 84(3): 265-272.

Kimmell KT, Petraglia AL, Bakos R, Rodenhouse T, Maurer PK, Pilcher WH. "The history of neurosurgery at the University of Rochester." Journal of neurosurgery.. 2014 Oct; 121(4):989-94. Epub 2014 Aug 08.

Kimmell, KT; Petraglia, AL; Bakos, R; Rodenhouse, T; Maurer, PK; Pilcher, WH. "The history of neurosurgery at the University of Rochester". Journal of Neurosurgery. 2014; 121(4): 989-994.

Kimmell KT, Petraglia AL, Ballou MA, Pilcher WH. "William P. Van Wagenen (1897-1961): pupil, mentor, and neurosurgical pioneer." Journal of neurosurgery.. 2013 Sep; 119(3):789-95. Epub 2013 May 10.

Johnson MD, O'Connell M, Facik M, Maurer P, Jahromi B, Pilcher W. "Cerebrospinal fluid stimulates leptomeningeal and meningioma cell proliferation and activation of STAT3." Journal of neuro-oncology.. 2012 Mar; 107(1):121-31. Epub 2011 Oct 05.

Johnson MD, O'Connell M, Pilcher W. "Lopinavir inhibits meningioma cell proliferation by Akt independent mechanism." Journal of neuro-oncology.. 2011 Feb; 101(3):441-8. Epub 2010 Jul 02.

Johnson MD, O'Connell MJ, Pilcher W, Reeder JE. "Fibroblast growth factor receptor-3 expression in meningiomas with stimulation of proliferation by the phosphoinositide 3 kinase-Akt pathway." Journal of neurosurgery.. 2010 May; 112(5):934-9.

Johnson, MD; O'Connell, M; Pilcher, W. "Lopinavir inhibits meningioma cell proliferation by Akt independent mechanism". Journal of Neuro-oncology. 2010; 10.

Johnson MD, O'Connell MJ, Vito F, Pilcher W. "Bone morphogenetic protein 4 and its receptors are expressed in the leptomeninges and meningiomas and signal via the Smad pathway." Journal of neuropathology and experimental neurology.. 2009 Nov; 68(11):1177-83.

Biswas T, Okunieff P, Schell MC, Smudzin T, Pilcher WH, Bakos RS, Vates GE, Walter KA, Wensel A, Korones DN, Milano MT. "Stereotactic radiosurgery for glioblastoma: retrospective analysis." Radiation oncology.. 2009 Mar 17; 4:11. Epub 2009 Mar 17.

Oberheim NA, Takano T, Han X, He W, Lin JH, Wang F, Xu Q, Wyatt JD, Pilcher W, Ojemann JG, Ransom BR, Goldman SA, Nedergaard M. "Uniquely hominid features of adult human astrocytes." The Journal of neuroscience : the official journal of the Society for Neuroscience.. 2009 Mar 11; 29(10):3276-87.

Sim FJ, Lang JK, Ali TA, Roy NS, Vates GE, Pilcher WH, Goldman SA. "Statin treatment of adult human glial progenitors induces PPAR gamma-mediated oligodendrocytic differentiation." Glia.. 2008 Jul; 56(9):954-62.

Johnson VE, Huang JH, Pilcher WH. "Special cases: mechanical ventilation of neurosurgical patients." Critical care clinics.. 2007 Apr; 23(2):275-90, x.

Sim FJ, Lang JK, Waldau B, Roy NS, Schwartz TE, Pilcher WH, Chandross KJ, Natesan S, Merrill JE, Goldman SA, Goldmanm SA. "Complementary patterns of gene expression by human oligodendrocyte progenitors and their environment predict determinants of progenitor maintenance and differentiation." Annals of neurology.. 2006 May; 59(5):763-79.

Okunieff P, Schell MC, Ruo R, Hale ER, O'Dell WG, Pilcher W. "Long-term management of patients with multiple brain metastases after shaped beam radiosurgery. Case report and review of the literature." Journal of neurosurgery.. 2004 Nov; 101 Suppl 3:406-12.

Hiwatashi A, Danielson B, Moritani T, Bakos RS, Rodenhause TG, Pilcher WH, Westesson PL. "Axial loading during MR imaging can influence treatment decision for symptomatic spinal stenosis." AJNR. American journal of neuroradiology.. 2004 Feb; 25(2):170-4.

Lynd-Balta E, Pilcher WH, Joseph SA. "AMPA receptor alterations precede mossy fiber sprouting in young children with temporal lobe epilepsy." Neuroscience.. 2004 126(1):105-14.

Stroup E, Langfitt J, Berg M, McDermott M, Pilcher W, Como P. "Predicting verbal memory decline following anterior temporal lobectomy (ATL)." Neurology.. 2003 Apr 22; 60(8):1266-73.

Yoshiura T, Shrier DA, Pilcher WH, Saunders CA. "Case report: Hemispheric juvenile pilocytic astrocytoma with extreme exophytic growth." Clinical radiology.. 2001 May; 56(5):427-30.

Qian J, Rubio A, Powers JM, Rosenblum MK, Pilcher WH, Shrier DA, Stein BM, Ito M, Iannucci A. "Fibro-osseous lesions of the central nervous system: report of four cases and literature review." The American journal of surgical pathology.. 1999 Oct; 23(10):1270-5.

Shrier DA, Melville D, Millet D, Qian J, Millet D, Nelson C, Pilcher W, Powers JM. "Fibro-osseous lesions involving the brain: MRI." Neuroradiology.. 1999 Jan; 41(1):18-21.

Mullins KJ, Rubio A, Myers SP, Korones DN, Pilcher WH. "Malignant ependymomas in a patient with Turcot's syndrome: case report and management guidelines." Surgical neurology.. 1998 Mar; 49(3):290-4.

McBride MC, Bronstein KS, Bennett B, Erba G, Pilcher W, Berg MJ. "Failure of standard magnetic resonance imaging in patients with refractory temporal lobe epilepsy." Archives of neurology.. 1998 Mar; 55(3):346-8.

Yoshiura T, Shrier DA, Pilcher WH, Rubio A. "Cervical spinal meningioma with unusual MR contrast enhancement." AJNR. American journal of neuroradiology.. 1998 19(6):1040-2.

Torres CF, Korones DN, Pilcher W. "Multiple ependymomas in a patient with Turcot's syndrome." Medical and pediatric oncology.. 1997 Jan; 28(1):59-61.

Torres,C. F.; Korones,D. N.; Pilcher,W.;. "Multiple ependymomas in a patient with Turcot's syndrome" . Medical & Pediatric Oncology. 1997; 28(1): 59-61.

Song J, Combs CK, Pilcher WH, Song LY, Utal AK, Coleman PD. "Low initial tau phosphorylation in human brain biopsy samples." Neurobiology of aging.. 1997 18(5):475-81.

Pilcher WH, Langfitt J. "Analysis of outcome: temporal lobe resection." Clinical neurosurgery. 1997 44:401-21.

Lynd-Balta E, Pilcher WH, Joseph SA. "Adrenocorticotropic hormone immunoreactivity in the hippocampal formation of temporal lobe epilepsy patients." Epilepsia.. 1996 Nov; 37(11):1081-7.

Lynd-Balta E, Pilcher WH, Joseph SA. "Distribution of AMPA receptor subunits in the hippocampal formation of temporal lobe epilepsy patients." Neuroscience.. 1996 May; 72(1):15-29.

Valanne L, Ketonen L, Barsotti J, Peterson P, Pilcher W. "Posttraumatic nonfunctioning arm." Journal of child neurology.. 1995 Jan; 10(1):30-1.

Shady JA, Bland LI, Kazee AM, Pilcher WH. "Osteoma of the frontoethmoidal sinus with secondary brain abscess and intracranial mucocele: case report." Neurosurgery.. 1994 May; 34(5):920-3; discussion 923.

Prasad AV, Pilcher WH, Joseph SA. "Nuclear factor-kappa B in rat brain: enhanced DNA-binding activity following convulsant-induced seizures." Neuroscience letters.. 1994 Mar 28; 170(1):145-8.

Pilcher WH, Silbergeld DL, Berger MS, Ojemann GA. "Intraoperative electrocorticography during tumor resection: impact on seizure outcome in patients with gangliogliomas." Journal of neurosurgery.. 1993 Jun; 78(6):891-902.

Pilcher WH, Rusyniak WG. "Complications of epilepsy surgery." Neurosurgery clinics of North America.. 1993 Apr; 4(2):311-25.

Radley MG, McDonald JV, Pilcher WH, Wilbur DC. "Late solitary cerebral metastases from renal cell carcinoma: report of two cases." Surgical neurology.. 1993 Mar; 39(3):230-4.

Rusyniak WG, Ireland PD, Radley MG, Pilcher WH, Okawara SH. "Ultrasonographic and electrophysiological adjuncts to surgery within the brain stem: technical note." Neurosurgery.. 1992 Oct; 31(4):798-800; discussion 800-1.

Rusyniak WG, Peterson PC, Okawara SH, Pilcher WH, George ED. "Acute subdural hematoma after aneurysmal rupture; evacuation with aneurysmal clipping after emergent infusion computed tomography: case report." Neurosurgery.. 1992 Jul; 31(1):129-31; discussion 131-2.

Pilcher WH, Locharernkul C, Primrose D, Ojemann LM, Ojemann GA. "Update in epilepsy. Part III: Surgical therapy of intractable epilepsy." New York state journal of medicine.. 1992 Mar; 92(3):92-6.

Primrose D, Locharernkul C, Pilcher WH, Ojemann LM, Ojemann GA. "Special considerations in the treatment of epilepsy." New York state journal of medicine.. 1992 Feb; 92(2):53-6.

Locharernkul C, Primrose D, Pilcher WH, Ojemann LM, Ojemann GA. "Update in epilepsy. Part I: Diagnosis and treatment of epilepsy." New York state journal of medicine.. 1992 Jan; 92(1):14-7.

Vossler DG, Wilkus RJ, Pilcher WH, Farwell JR. "Epilepsy in schizencephaly: abnormal cortical organization studied by somatosensory evoked potentials." Epilepsia.. 1992 33(3):487-94.

LeRoux PD, Berger MS, Haglund MM, Pilcher WH, Ojemann GA. "Resection of intrinsic tumors from nondominant face motor cortex using stimulation mapping: report of two cases." Surgical neurology.. 1991 Jul; 36(1):44-8.

Joseph SA, Pilcher WH, Knigge KM, Abood LG, Michael GJ. "Arginine vasopressin-anti-idiotypic immunostaining of human brain cells." Journal of neuroendocrinology.. 1990 Oct 1; 2(5):659-65.

Pilcher WH, Joseph SA, McDonald JV. "Immunocytochemical localization of pro-opiomelanocortin neurons in human brain areas subserving stimulation analgesia." Journal of neurosurgery.. 1988 Apr; 68(4):621-9.

Pilcher WH, Joseph SA. "Differential sensitivity of hypothalamic and medullary opiocortin and tyrosine hydroxylase neurons to the neurotoxic effects of monosodium glutamate (MSG)." Peptides.. 1986 7(5):783-9.

Almqvist PM, Knigge KM, Kuenzig M, Joseph SA, Pilcher WH, Schwartz SI. "Pulmonary platelet trapping induced by beta-endorphin injection in the cerebrospinal fluid in dogs." Surgery.. 1985 Aug; 98(2):344-9.

Joseph SA, Pilcher WH, Knigge KM. "Anatomy of the corticotropin-releasing factor and opiomelanocortin systems of the brain." Federation proceedings.. 1985 Jan; 44(1 Pt 1):100-7.

Warren PH, Pilcher W, Coopersmith R. "Stressors produce a concurrent decrease and increase in reflex amplitude in rats treated with naloxone." Life sciences.. 1984 Sep 24; 35(13):1409-14.

Pilcher WH, Joseph SA. "Co-localization of CRF-ir perikarya and ACTH-ir fibers in rat brain." Brain research.. 1984 May 7; 299(1):91-102.

Joseph SA, Pilcher WH, Bennett-Clarke C. "Immunocytochemical localization of ACTH perikarya in nucleus tractus solitarius: evidence for a second opiocortin neuronal system." Neuroscience letters.. 1983 Aug 8; 38(3):221-5.

Romagnano MA, Chafel TL, Pilcher WH, Joseph SA. "The distribution of enkephalin in the mediobasal hypothalamus of the mouse brain: effects of neonatal administration of MSG." Brain research.. 1982 Mar 25; 236(2):497-504.

Romagnano MA, Pilcher WH, Bennett-Clarke C, Chafel TL, Joseph SA. "Distribution of somatostatin in the mouse brain: effects of neonatal MSG treatment." Brain research.. 1982 Feb 25; 234(2):387-98.

Books & Chapters

Chapter Title: Epilepsy Surgery: Outcomes and Complications
Book Title: Youmans Neurological Surgery
Author List: Petraglia, A; Kaufman, C; Pilcher, W
Published By: Elsevier2011 in Philadelphia

Chapter Title: Awake Surgery for Epilepsy
Book Title: The Treatment of Epilepsy
Author List: Kaufman, C.B., Pilcher, W.H.
Edited By: Shorvon, S.D.
Published By: Wiley-Blackwell2009

Chapter Title: Epilepsy surgery: outcome and complications
Book Title: Youmans Neurological Surgery
Author List: Pilcher WH
Edited By: HR Winn and JR Youmans
Published By: W. B. Saunders2004 in Philadelphia

Chapter Title: Epilepsy surgery and anesthesia for awake craniotomy
Book Title: Progress in Anesthesiology
Author List: Roberts W, Gingrich K, and Pilcher WH
Published By: Dannemiller Memorial Educational Foundation1997 in San Antonio

Chapter Title: Neurosurgery.
Book Title: Principles of surgery: Companion handbook.
Author List: Pilcher WH, and Maurer PK
Edited By: SI Schwartz
Published By: McGraw Hill1994 in New York

Chapter Title: Complications of epilepsy surgery.
Book Title: Post-operative complications of intracranial neurosurgery.
Author List: Pilcher WH, and Ojemann GA.
Edited By: K Post, E Friedman and P McCormick.
Published By: Thieme Medical and Scientific Publishers1993 in New York

Chapter Title: Presurgical evaluation and treatment of epilepsy.
Book Title: Brain surgery: complication avoidance and management.
Author List: Pilcher WH, and Ojemann GA.
Edited By: MJ Apuzzo
Published By: Churchill Livingstone1993 in New York

Chapter Title: Complications of epilepsy surgery.
Book Title: Surgical Treatment of the Epilepsies
Author List: Pilcher WH, Roberts PW, Flanigin HF, Crandall PH, Wieser HG, Ojemann GA, and Peacock W.
Edited By: J Engel.
Published By: Raven Press, Ltd.1993 in New York

Chapter Title: Neurological Surgery.
Book Title: Principles of surgery: Companion handbook.
Author List: Pilcher WH
Edited By: SI Schwartz
Published By: McGraw Hill1989 in New York