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Richard John Looney, M.D.

Publications

Showing all 126 journal articles & 4 books available

Journal Articles

1/2023
Long A, Kleiner A, Looney RJ. "Immune dysregulation." The Journal of allergy and clinical immunology.. 2023 Jan; 151(1):70-80.

5/13/2022
Holm M, Saraswat M, Joenväärä S, Seppo A, Looney RJ, Tohmola T, Renkonen J, Renkonen R, Järvinen KM. "Quantitative glycoproteomics of human milk and association with atopic disease." PloS one.. 2022 May 13; 17(5):e0267967. Epub 2022 May 13.

2022
Järvinen KM, Davis EC, Bevec E, Jackson CM, Pizzarello C, Catlin E, Klein M, Sunkara A, Diaz N, Miller J, Martina CA, Thakar J, Seppo AE, Looney RJ, . "Biomarkers of Development of Immunity and Allergic Diseases in Farming and Non-farming Lifestyle Infants: Design, Methods and 1 Year Outcomes in the "Zooming in to Old Order Mennonites" Birth Cohort Study." Frontiers in pediatrics.. 2022 10:916184. Epub 2022 Jul 06.

10/27/2021
Barnas JL, Albrecht J, Meednu N, Alzamareh DF, Baker C, McDavid A, Looney RJ, Anolik JH. "B Cell Activation and Plasma Cell Differentiation Are Promoted by IFN-? in Systemic Lupus Erythematosus." The Journal of immunology : official journal of the American Association of Immunologists.. 2021 Oct 27; Epub 2021 Oct 27.

8/2021
Harrison BM, Looney RJ, Williams ZR, DiLoreto DA. "Steroid Allergy in a Patient With Behçet's Disease." Ophthalmic surgery, lasers & imaging retina.. 2021 Aug; 52(8):447-449. Epub 2021 Aug 01.

4/27/2021
Seppo AE, Bu K, Jumabaeva M, Thakar J, Choudhury R, Yonemitsu C, Bode L, Martina CA, Allen M, Tamburini S, Piras E, Wallach DS, Looney RJ, Clemente JC, Järvinen KM. "Infant Gut Microbiome Is Enriched with Bifidobacteria longumssp. infantisin Old Order Mennoniteswith Traditional Farming Lifestyle." Allergy.. 2021 Apr 27; Epub 2021 Apr 27.

2021
Seppo AE, Choudhury R, Pizzarello C, Palli R, Fridy S, Rajani PS, Stern J, Martina C, Yonemitsu C, Bode L, Bu K, Tamburini S, Piras E, Wallach DS, Allen M, Looney RJ, Clemente JC, Thakar J, Järvinen KM. "Traditional Farming Lifestyle in Old Older Mennonites Modulates Human Milk Composition." Frontiers in immunology.. 2021 12:741513. Epub 2021 Oct 11.

6/9/2020
Gao L, Liesveld J, Anolik J, Mcdavid A, Looney RJ. "IFN signaling inhibits osteogenesis in human SLE bone marrow." Lupus.. 2020 Jun 9; :961203320930088. Epub 2020 Jun 09.

12/2019
Barnas JL, Looney RJ, Anolik JH. "B cell targeted therapies in autoimmune disease." Current opinion in immunology.. 2019 Dec; 61:92-99. Epub 2019 Nov 14.

5/23/2019
Gao L, Slack M, Barnas JL, McDavid A, Anolik J, Looney RJ. "Cell Senescence in Lupus." Current rheumatology reports.. 2019 May 23; 21(7):32. Epub 2019 May 23.

1/14/2019
Gao L, Slack M, McDavid A, Anolik J, Looney RJ. "Cell Senescence in Lupus." Current rheumatology reports.. 2019 Jan 14; 21(2):1. Epub 2019 Jan 14.

2019
Richardson CT, Slack MA, Dhillon G, Marcus CZ, Barnard J, Palanichamy A, Sanz I, Looney RJ, Anolik JH. "Failure of B Cell Tolerance in CVID." Frontiers in immunology.. 2019 10:2881. Epub 2019 Dec 10.

10/8/2018
Gomez Mendez LM, Cascino MD, Garg J, Katsumoto TR, Brakeman P, Dall'Era M, Looney RJ, Rovin B, Dragone L, Brunetta P. "Peripheral Blood B Cell Depletion after Rituximab and Complete Response in Lupus Nephritis." Clinical journal of the American Society of Nephrology : CJASN.. 2018 Oct 8; 13(10):1502-1509. Epub 2018 Aug 08.

8/2017
Gao L, Bird AK, Meednu N, Dauenhauer K, Liesveld J, Anolik J, Looney RJ. "Bone Marrow-Derived Mesenchymal Stem Cells From Patients With Systemic Lupus Erythematosus Have a Senescence-Associated Secretory Phenotype Mediated by a Mitochondrial Antiviral Signaling Protein-Interferon-? Feedback Loop." Arthritis & rheumatology.. 2017 Aug; 69(8):1623-1635. Epub 2017 Jul 11.

11/2016
Martina C, Looney RJ, Marcus C, Allen M, Stahlhut R. "Prevalence of allergic disease in Old Order Mennonites in New York." Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.. 2016 Nov; 117(5):562-563.e1. Epub 2016 Sep 06.

8/20/2015
Stohl W, Merrill JT, Looney RJ, Buyon J, Wallace DJ, Weisman MH, Ginzler EM, Cooke B, Holloway D, Kaliyaperumal A, Kuchimanchi KR, Cheah TC, Rasmussen E, Ferbas J, Belouski SS, Tsuji W, Zack DJ. "Treatment of systemic lupus erythematosus patients with the BAFF antagonist "peptibody" blisibimod (AMG 623/A-623): results from randomized, double-blind phase 1a and phase 1b trials." Arthritis research & therapy.. 2015 Aug 20; 17:215. Epub 2015 Aug 20.

2015
Adlowitz DG, Barnard J, Biear JN, Cistrone C, Owen T, Wang W, Palanichamy A, Ezealah E, Campbell D, Wei C, Looney RJ, Sanz I, Anolik JH. "Expansion of Activated Peripheral Blood Memory B Cells in Rheumatoid Arthritis, Impact of B Cell Depletion Therapy, and Biomarkers of Response." PloS one.. 2015 10(6):e0128269. Epub 2015 Jun 05.

4/2012
Rovin BH, Furie R, Latinis K, Looney RJ, Fervenza FC, Sanchez-Guerrero J, Maciuca R, Zhang D, Garg JP, Brunetta P, Appel G, . "Efficacy and safety of rituximab in patients with active proliferative lupus nephritis: the Lupus Nephritis Assessment with Rituximab study." Arthritis and rheumatism.. 2012 Apr; 64(4):1215-26. Epub 2012 Jan 09.

2/2012
Ichikawa HT, Conley T, Muchamuel T, Jiang J, Lee S, Owen T, Barnard J, Nevarez S, Goldman BI, Kirk CJ, Looney RJ, Anolik JH. "Beneficial effect of novel proteasome inhibitors in murine lupus via dual inhibition of type I interferon and autoantibody-secreting cells." Arthritis and rheumatism.. 2012 Feb; 64(2):493-503.

2011
Kobie JJ, Zheng B, Bryk P, Barnes M, Ritchlin CT, Tabechian DA, Anandarajah AP, Looney RJ, Thiele RG, Anolik JH, Coca A, Wei C, Rosenberg AF, Feng C, Treanor JJ, Lee FE, Sanz I. "Decreased influenza-specific B cell responses in rheumatoid arthritis patients treated with anti-tumor necrosis factor." Arthritis research & therapy.. 2011 13(6):R209. Epub 2011 Dec 16.

12/2010
Qi Y, Operario DJ, Oberholzer CM, Kobie JJ, Looney RJ, Georas SN, Mosmann TR. "Human basophils express amphiregulin in response to T cell-derived IL-3." The Journal of allergy and clinical immunology.. 2010 Dec; 126(6):1260-6.e4. Epub 2010 Oct 30.

9/2010
Marston B, Looney RJ. "Connective tissue diseases: Translating the effects of BAFF in SLE." Nature reviews. Rheumatology.. 2010 Sep; 6(9):503-4.

3/26/2010
Looney RJ. "B cell-targeted therapies for systemic lupus erythematosus: an update on clinical trial data." Drugs.. 2010 Mar 26; 70(5):529-40.

2/2010
John Looney R, Anolik J, Sanz I. "A perspective on B-cell-targeting therapy for SLE." Modern rheumatology. 2010 Feb; 20(1):1-10. Epub 2009 Aug 08.

1/2010
Bingham CO, Looney RJ, Deodhar A, Halsey N, Greenwald M, Codding C, Trzaskoma B, Martin F, Agarwal S, Kelman A. "Immunization responses in rheumatoid arthritis patients treated with rituximab: results from a controlled clinical trial." Arthritis and rheumatism.. 2010 Jan; 62(1):64-74.

1/2010
Kwon JB, Kleiner A, Ishida K, Godown J, Ciafaloni E, Looney RJ. "Hydroxychloroquine-induced myopathy." Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases.. 2010 Jan; 16(1):28-31.

12/2009
Anolik JH, Looney RJ, Lund FE, Randall TD, Sanz I. "Insights into the heterogeneity of human B cells: diverse functions, roles in autoimmunity, and use as therapeutic targets." Immunologic research.. 2009 Dec; 45(2-3):144-58. Epub 2009 Apr 07.

7/2009
Coca A, Bundy KW, Marston B, Huggins J, Looney RJ. "Macrophage activation syndrome: serological markers and treatment with anti-thymocyte globulin." Clinical immunology : the official journal of the Clinical Immunology Society.. 2009 Jul; 132(1):10-8. Epub 2009 Mar 17.

5/15/2009
Palanichamy A, Barnard J, Zheng B, Owen T, Quach T, Wei C, Looney RJ, Sanz I, Anolik JH. "Novel human transitional B cell populations revealed by B cell depletion therapy." The Journal of immunology : official journal of the American Association of Immunologists.. 2009 May 15; 182(10):5982-93.

1/2009
Brown RJ, Rother KI, Artman H, Mercurio MG, Wang R, Looney RJ, Cowen EW. "Minocycline-induced drug hypersensitivity syndrome followed by multiple autoimmune sequelae." Archives of dermatology.. 2009 Jan; 145(1):63-6.

2009
Looney RJ. "Update on the use of rituximab for intractable rheumatoid arthritis." Open access rheumatology : research and reviews.. 2009 1:83-94. Epub 2009 Jun 26.

12/2008
Albert D, Dunham J, Khan S, Stansberry J, Kolasinski S, Tsai D, Pullman-Mooar S, Barnack F, Striebich C, Looney RJ, Prak ET, Kimberly R, Zhang Y, Eisenberg R. "Variability in the biological response to anti-CD20 B cell depletion in systemic lupus erythaematosus." Annals of the rheumatic diseases.. 2008 Dec; 67(12):1724-31. Epub 2008 Feb 04.

11/2008
Kleiner A, Looney RJ. "Is rituximab suitable for use as a first-line biologic therapy for RA?" Nature clinical practice. Rheumatology.. 2008 Nov; 4(11):574-5. Epub 2008 Sep 09.

4/2008
Mehta LR, Samuelsson MK, Kleiner AK, Goodman AD, Anolik JH, Looney RJ, Schwid SR. "Neuromyelitis optica spectrum disorder in a patient with systemic lupus erythematosus and anti-phospholipid antibody syndrome." Multiple sclerosis : clinical and laboratory research.. 2008 Apr; 14(3):425-7. Epub 2008 Jan 21.

2/2008
Nicholas MW, Dooley MA, Hogan SL, Anolik J, Looney J, Sanz I, Clarke SH. "A novel subset of memory B cells is enriched in autoreactivity and correlates with adverse outcomes in SLE." Clinical immunology : the official journal of the Clinical Immunology Society.. 2008 Feb; 126(2):189-201.

1/2008
Looney RJ, Srinivasan R, Calabrese LH. "The effects of rituximab on immunocompetency in patients with autoimmune disease." Arthritis and rheumatism.. 2008 Jan; 58(1):5-14.

2008
Brown, RJ.; Rother, KI.; Mercurio, MG.; Wang, R.; Looney, RJ.; Cowen, EW. "Minocycline-induced drug hypersensitivity syndrome followed by multiple autoimmune sequelae". Archives of Dermatology. 2008; .

2008
Kleiner, A.; Looney, RJ. "Commentary: rituximab as first line therapy for rheumatoid arthritis". Nature Clinical Practice in Rheumatology. 2008; .

10/2007
Reddy MB, Looney RJ, Utell MJ, Plotzke KP, Andersen ME. "Modeling of human dermal absorption of octamethylcyclotetrasiloxane (D(4)) and decamethylcyclopentasiloxane (D(5))." Toxicological sciences : an official journal of the Society of Toxicology.. 2007 Oct; 99(2):422-31. Epub 2007 Jul 14.

10/2007
Ravikumar R, Anolik J, Looney RJ. "Vaccine responses in patients with rheumatoid arthritis." Current rheumatology reports.. 2007 Oct; 9(5):407-15.

9/2007
Anolik JH, Barnard J, Owen T, Zheng B, Kemshetti S, Looney RJ, Sanz I. "Delayed memory B cell recovery in peripheral blood and lymphoid tissue in systemic lupus erythematosus after B cell depletion therapy." Arthritis and rheumatism.. 2007 Sep; 56(9):3044-56.

7/2007
Looney RJ, Stohl W. "New and promising treatments for rheumatoid arthritis." The American journal of orthopedics.. 2007 Jul; 36(7 Suppl):18-23.

6/2007
Looney RJ, Diamond B, Holers VM, Levesque MC, Moreland L, Nahm MH, St Clair EW, . "Guidelines for assessing immunocompetency in clinical trials for autoimmune diseases." Clinical immunology : the official journal of the Clinical Immunology Society.. 2007 Jun; 123(3):235-43. Epub 2007 Feb 27.

5/2007
Looney RJ. "Will targeting B cells be the answer for Sjögren's syndrome?" Arthritis and rheumatism.. 2007 May; 56(5):1371-7.

1/1/2007
Sanz I, Anolik JH, Looney RJ. "B cell depletion therapy in autoimmune diseases." Frontiers in bioscience : a journal and virtual library.. 2007 Jan 1; 12:2546-67. Epub 2007 Jan 01.

2007
Anolik, JH.; Barnard, J.; Owen, T; Zheng, B; Kemshetti, S.; Looney, RJ.; Sanz, I. "Delayed memory B cell recovery in peripheral blood and lymphoid tissue in systemic lupus erythematosus after B cell depletion therapy". Arthritis & Rheumatism. 2007; 56(9): 3004-3056.

2007
A novel subset of memory B cells is enriched in autoreactivity and correlates with adverse outcomes in SLE. "Nicholas, M.W.; Dooley, M.S.; Hogan, S.; Anolik, J.; Looney, R.J.; Sanz, I.; Clarke, S.H." 2007; 56: 3004-3056.

2007
Ravikumar, R.; Anolik, J.; Looney, R. "Vaccine responses in patients with rheumatoid arthritis". Current Rheumatology Reports. 2007; 9(5): 407-415.

10/2006
Stohl W, Looney RJ. "B cell depletion therapy in systemic rheumatic diseases: different strokes for different folks?" Clinical immunology : the official journal of the Clinical Immunology Society.. 2006 Oct; 121(1):1-12. Epub 2006 May 11.

4/2006
Schwarz EM, Looney RJ, Drissi MH, O'Keefe RJ, Boyce BF, Xing L, Ritchlin CT. "Autoimmunity and bone." Annals of the New York Academy of Sciences.. 2006 Apr; 1068:275-83.

2/2006
Looney RJ, Anolik J, Sanz I. "New therapies for systemic lupus erythematosus: cellular targets." Rheumatic diseases clinics of North America.. 2006 Feb; 32(1):201-15, xi.

1/2006
Looney RJ, Schwarz EM, Boyd A, O'Keefe RJ. "Periprosthetic osteolysis: an immunologist's update." Current opinion in rheumatology.. 2006 Jan; 18(1):80-7.

2006
Schwarz, EM.; Looney, RJ.; Drissi, H.; O'Keefe, RJ.; Boyce, BF.; Zing, L.; Ritchlin, CT. "Autoimmunity and bone". Annals of the New York Academy of Science. 2006; 1068: 275-283.

2006
Looney, R.J. "B cell-targeted therapy for rheumatoid arthritis: an update on the evidence". Drugs. 2006; 66: 325-339.

2006
Looney RJ, Huggins J. "Use of intravenous immunoglobulin G (IVIG)." Best practice & research. Clinical haematology.. 2006 19(1):3-25.

2006
Looney RJ. "B cell-targeted therapy for rheumatoid arthritis: an update on the evidence." Drugs.. 2006 66(5):625-39.

12/2005
Eisenberg R, Looney RJ. "The therapeutic potential of anti-CD20 "what do B-cells do?"." Clinical immunology : the official journal of the Clinical Immunology Society.. 2005 Dec; 117(3):207-13. Epub 2005 Sep 19.

11/2005
Looney RJ. "Discovering that B cells are important in rheumatoid arthritis." The Journal of rheumatology.. 2005 Nov; 32(11):2067-9.

2005
Schwarz, EM.; O'Keefe, RJ.; Zing, L.; Looney, RJ.; Ritchlin, CT. "Receptor activator of nuclear kappa ligand and osteoprotegerin: where are we now and what about future treatment uses?". Current Opinion in Orthopedics. 2005; 16: 370-375.

2005
Looney RJ, Anolik J, Sanz I. "Treatment of SLE with anti-CD20 monoclonal antibody." Current directions in autoimmunity. 2005 8:193-205.

11/2004
Anolik JH, Barnard J, Cappione A, Pugh-Bernard AE, Felgar RE, Looney RJ, Sanz I. "Rituximab improves peripheral B cell abnormalities in human systemic lupus erythematosus." Arthritis and rheumatism.. 2004 Nov; 50(11):3580-90.

8/15/2004
Huggins JL, Looney RJ. "Allergen immunotherapy." American family physician.. 2004 Aug 15; 70(4):689-96.

8/2004
Looney RJ, Anolik JH, Campbell D, Felgar RE, Young F, Arend LJ, Sloand JA, Rosenblatt J, Sanz I. "B cell depletion as a novel treatment for systemic lupus erythematosus: a phase I/II dose-escalation trial of rituximab." Arthritis and rheumatism.. 2004 Aug; 50(8):2580-9.

7/2004
Joshi S, Scott G, Looney RJ. "A successful challenge in a patient with vancomycin-induced linear IgA dermatosis." Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.. 2004 Jul; 93(1):101-3.

5/2004
Looney RJ, Anolik J, Sanz I. "B cells as therapeutic targets for rheumatic diseases." Current opinion in rheumatology.. 2004 May; 16(3):180-5.

5/2004
Claus AM, Totterman SM, Sychterz CJ, Tamez-Peña JG, Looney RJ, Engh CA. "Computed tomography to assess pelvic lysis after total hip replacement." Clinical orthopaedics and related research.. 2004 May; (422):167-74.

1/2004
Li P, Schwarz EM, O'Keefe RJ, Ma L, Looney RJ, Ritchlin CT, Boyce BF, Xing L. "Systemic tumor necrosis factor alpha mediates an increase in peripheral CD11bhigh osteoclast precursors in tumor necrosis factor alpha-transgenic mice." Arthritis and rheumatism.. 2004 Jan; 50(1):265-76.

2004
Ritchlin, CT.; Schwarz, EM.; O'Keefe, RJ.; Looney, RJ. "RANK, RANKL and OPG in inflammatory arthritis and periprosthetic osteolysis". Journal of Musculoskeletal Neuronal Interaction. 2004; 4: 276-284.

2004
Looney RJ, Anolik J, Sanz I. "B lymphocytes in systemic lupus erythematosus: lessons from therapy targeting B cells." Lupus.. 2004 13(5):381-90.

11/2003
Schwarz EM, Campbell D, Totterman S, Boyd A, O'Keefe RJ, Looney RJ. "Use of volumetric computerized tomography as a primary outcome measure to evaluate drug efficacy in the prevention of peri-prosthetic osteolysis: a 1-year clinical pilot of etanercept vs. placebo." Journal of orthopaedic research : official publication of the Orthopaedic Research Society.. 2003 Nov; 21(6):1049-55.

10/2003
Anolik J, Sanz I, Looney RJ. "B cell depletion therapy in systemic lupus erythematosus." Current rheumatology reports.. 2003 Oct; 5(5):350-6.

9/2003
Anolik J, Looney RJ, Bottaro A, Sanz I, Young F. "Down-regulation of CD20 on B cells upon CD40 activation." European journal of immunology.. 2003 Sep; 33(9):2398-409.

2/2003
Anolik JH, Campbell D, Felgar RE, Young F, Sanz I, Rosenblatt J, Looney RJ. "The relationship of FcgammaRIIIa genotype to degree of B cell depletion by rituximab in the treatment of systemic lupus erythematosus." Arthritis and rheumatism.. 2003 Feb; 48(2):455-9.

10/2002
Looney RJ. "Treating human autoimmune disease by depleting B cells." Annals of the rheumatic diseases.. 2002 Oct; 61(10):863-6.

3/1/2002
Looney RJ, Falsey AR, Walsh E, Campbell D. "Effect of aging on cytokine production in response to respiratory syncytial virus infection." The Journal of infectious diseases.. 2002 Mar 1; 185(5):682-5. Epub 2002 Feb 14.

2002
Looney,R. J.; Boyd,A.; Totterman,S.; Seo,G. S.; Tamez-Pena,J.; Campbell,D.; Novotny,L.; Olcott,C.; Martell,J.; Hayes,F. A.; O'Keefe,R. J.; Schwarz,E. M. "Volumetric computerized tomography as a measurement of periprosthetic acetabular osteolysis and its correlation with wear" . Arthritis Research (Print). 2002; 4(1): 59,63.

2002
Looney RJ, Boyd A, Totterman S, Seo GS, Tamez-Pena J, Campbell D, Novotny L, Olcott C, Martell J, Hayes FA, O'Keefe RJ, Schwarz EM. "Volumetric computerized tomography as a measurement of periprosthetic acetabular osteolysis and its correlation with wear." Arthritis research.. 2002 4(1):59-63. Epub 2001 Oct 03.

4/1/2001
Falsey AR, Walsh EE, Francis CW, Looney RJ, Kolassa JE, Hall WJ, Abraham GN. "Response of C-reactive protein and serum amyloid A to influenza A infection in older adults." The Journal of infectious diseases.. 2001 Apr 1; 183(7):995-9. Epub 2001 Feb 23.

1/2001
Looney RJ, Hasan MS, Coffin D, Campbell D, Falsey AR, Kolassa J, Agosti JM, Abraham GN, Evans TG. "Hepatitis B immunization of healthy elderly adults: relationship between naïve CD4+ T cells and primary immune response and evaluation of GM-CSF as an adjuvant." Journal of clinical immunology.. 2001 Jan; 21(1):30-6.

2001
Pollice,P. F.; Rosier,R. N.; Looney,R. J.; Puzas,J. E.; Schwarz,E. M.; O'Keefe,R. J. "Oral pentoxifylline inhibits release of tumor necrosis factor-alpha from human peripheral blood monocytes : a potential treatment for aseptic loosening of total joint components" . Journal of Bone and Joint Surgery. American volume. 2001; : 1057,1061.

2/2000
Hasan MS, Kallas EG, Thomas EK, Looney J, Campbell M, Evans TG. "Effects of interleukin-15 on in vitro human T cell proliferation and activation." Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research.. 2000 Feb; 20(2):119-23.

2000
Schwarz,E. M.; Looney,R. J.; O'Keefe,R. J. "Anti-TNF-alpha therapy as a clinical intervention for periprosthetic osteolysis" . Arthritis Research (Print). 2000; 2(3): 165,168.

10/1999
Falsey AR, Walsh EE, Looney RJ, Kolassa JE, Formica MA, Criddle MC, Hall WJ. "Comparison of respiratory syncytial virus humoral immunity and response to infection in young and elderly adults." Journal of medical virology.. 1999 Oct; 59(2):221-6.

7/1999
Hooper M, Kallas EG, Coffin D, Campbell D, Evans TG, Looney RJ. "Cytomegalovirus seropositivity is associated with the expansion of CD4+CD28- and CD8+CD28- T cells in rheumatoid arthritis." The Journal of rheumatology.. 1999 Jul; 26(7):1452-7.

6/18/1999
Evans TG, Kallas EG, Luque AE, Menegus M, McNair C, Looney RJ. "Expansion of the CD57 subset of CD8 T cells in HIV-1 infection is related to CMV serostatus." AIDS.. 1999 Jun 18; 13(9):1139-41.

2/1999
Looney RJ, Falsey A, Campbell D, Torres A, Kolassa J, Brower C, McCann R, Menegus M, McCormick K, Frampton M, Hall W, Abraham GN. "Role of cytomegalovirus in the T cell changes seen in elderly individuals." Clinical immunology : the official journal of the Clinical Immunology Society.. 1999 Feb; 90(2):213-9.

8/1998
Ritchlin C, Haas-Smith SA, Hicks D, Cappuccio J, Osterland CK, Looney RJ. "Patterns of cytokine production in psoriatic synovium." The Journal of rheumatology.. 1998 Aug; 25(8):1544-52.

8/1998
Looney RJ, Frampton MW, Byam J, Kenaga C, Speers DM, Cox C, Mast R, Klykken PC, Morrow PE, Utell MJ. "Acute respiratory exposure of human volunteers to octamethylcyclotetrasiloxane (D4): absence of immunological effects." Toxicological sciences : an official journal of the Society of Toxicology.. 1998 Aug; 44(2):214-20.

6/10/1997
Wei C, Willis RA, Tilton BR, Looney RJ, Lord EM, Barth RK, Frelinger JG. "Tissue-specific expression of the human prostate-specific antigen gene in transgenic mice: implications for tolerance and immunotherapy." Proceedings of the National Academy of Sciences of the United States of America.. 1997 Jun 10; 94(12):6369-74.

1997
Torres,A.; Utell,M. J.; Morow,P. E.; Voter,K. Z.; Whitin,J. C.; Cox,C.; Looney,R. J.; Speers,D. M.; Tsai,Y.; Frampton,M. W. "Airway inflammation in smokers and nonsmokers with varying responsiveness to ozone" . American Journal of Respiratory and Critical Care Medicine : An Official Journal of the American Thoracic Society, Medical Section of the American Lung Association. 1997; 156: 728,736.

11/1996
Fedyk ER, Adawi A, Looney RJ, Phipps RP. "Regulation of IgE and cytokine production by cAMP: implications for extrinsic asthma." Clinical immunology and immunopathology. 1996 Nov; 81(2):101-13.

7/1996
Wei C, Storozynsky E, McAdam AJ, Yeh KY, Tilton BR, Willis RA, Barth RK, Looney RJ, Lord EM, Frelinger JG. "Expression of human prostate-specific antigen (PSA) in a mouse tumor cell line reduces tumorigenicity and elicits PSA-specific cytotoxic T lymphocytes." Cancer immunology, immunotherapy : CII.. 1996 Jul; 42(6):362-8.

1/1996
Popescu NA, Sheehan MG, Kouides PA, Loughner JE, Condemi JJ, Looney RJ, Leddy JP. "Allergic reactions to cyclophosphamide: delayed clinical expression associated with positive immediate skin tests to drug metabolites in five patients." The Journal of allergy and clinical immunology.. 1996 Jan; 97(1 Pt 1):26-33.

1996
Blaine,T. A.; Rosier,R. N.; Puzas,J. E.; Looney,R. J.; Reynolds,P. R.; Reynolds,S. D.; O'Keefe,R. J. "Increased levels of tumor necrosis factor-alpha and interleukin-6 protein and messenger RNA in human peripheral blood monocytes due to titanium particles" . Journal of Bone and Joint Surgery. American volume. 1996; 78(8): 1181,1192.

12/1995
Utell MJ, Looney RJ. "Environmentally induced asthma." Toxicology letters.. 1995 Dec; 82-83:47-53.

10/1995
Fries KM, Sempowski GD, Gaspari AA, Blieden T, Looney RJ, Phipps RP. "CD40 expression by human fibroblasts." Clinical immunology and immunopathology. 1995 Oct; 77(1):42-51.

10/1995
Looney RJ, Hooper M, Pudiak D. "Costimulatory activity of human synovial fibroblasts." The Journal of rheumatology.. 1995 Oct; 22(10):1820-4.

9/1994
Fries KM, Blieden T, Looney RJ, Sempowski GD, Silvera MR, Willis RA, Phipps RP. "Evidence of fibroblast heterogeneity and the role of fibroblast subpopulations in fibrosis." Clinical immunology and immunopathology. 1994 Sep; 72(3):283-92.

6/15/1994
Liu Z, Pudiak D, Looney RJ. "Protein tyrosine phosphorylation triggered by human Fc gamma RII." Biochemical and biophysical research communications.. 1994 Jun 15; 201(2):829-34.

2/1994
Looney RJ, Pudiak D, Rosenfeld SI. "Cytokine production by mite-specific T cells from donors with mild atopic disease." The Journal of allergy and clinical immunology.. 1994 Feb; 93(2):476-83.

1994
Miller,C. H.; Pudiak,D. R.; Hatem,F.; Looney,R. J. "Accumulation of interferon gamma-producing TH1 helper T cells in nasal polyps" . Otolaryngology and head and neck surgery. 1994; 111(1): 51,58.

1994
Gavras, JB.; Frampton, MW.; Ryan, DH.; Levy, PC; Looney, RJ.; Cox, C.; Morrow, PE.; Utell, MJ. "Expression of membrane antigens on human alveolar macrophages after exposure to nitrogen dioxide". Inhalation Toxicology. 1994; 6: 633-647.

1993
Looney RJ. "Structure and function of human and mouse Fc gamma RII." Blood cells. 1993 19(2):353-9.

1991
Levy,P. C.; Utell,M. J.; Fleit,H. B.; Roberts,N. J.,Jr; Ryan,D. H.; Looney,R. J. "Characterization of human alveolar macrophage Fc gamma receptor III: a transmembrane glycoprotein that is shed under in vitro culture conditions" . American Journal of Respiratory Cell and Molecular Biology : An Official Journal of the American Thoracic Society, Medical Section of the American Lung Association. 1991; 5(4): 307,314.

7/1/1990
Anderson CL, Looney RJ, Culp DJ, Ryan DH, Fleit HB, Utell MJ, Frampton MW, Manganiello PD, Guyre PM. "Alveolar and peritoneal macrophages bear three distinct classes of Fc receptors for IgG." The Journal of immunology : official journal of the American Association of Immunologists.. 1990 Jul 1; 145(1):196-201.

6/1990
Iyer J, Duerst RE, Looney JN, Humphries RK, Abboud CN, Frantz CN. "An 80,000-kd glycoprotein cell surface antigen found only on nonhematopoietic cells in human bone marrow." Experimental hematology.. 1990 Jun; 18(5):384-9.

5/15/1990
Levy PC, Looney RJ, Shen L, Graziano RF, Fanger MW, Roberts NJ, Ryan DH, Utell MJ. "Human alveolar macrophage FcR-mediated cytotoxicity. Heteroantibody- versus conventional antibody-mediated target cell lysis." The Journal of immunology : official journal of the American Association of Immunologists.. 1990 May 15; 144(10):3693-700.

1/1/1989
Graziano RF, Looney RJ, Shen L, Fanger MW. "Fc gamma R-mediated killing by eosinophils." The Journal of immunology : official journal of the American Association of Immunologists.. 1989 Jan 1; 142(1):230-5.

10/15/1988
Looney RJ, Anderson CL, Ryan DH, Rosenfeld SI. "Structural polymorphism of the human platelet Fc gamma receptor." The Journal of immunology : official journal of the American Association of Immunologists.. 1988 Oct 15; 141(8):2680-3.

3/1/1988
Liesveld JL, Abboud CN, Looney RJ, Ryan DH, Brennan JK. "Expression of IgG Fc receptors in myeloid leukemic cell lines. Effect of colony-stimulating factors and cytokines." The Journal of immunology : official journal of the American Association of Immunologists.. 1988 Mar 1; 140(5):1527-33.

12/1987
Williams JM, Gorevic PD, Looney RJ, Abraham GN. "Isoelectric focusing characterization of IgM-VKiiib immunoglobulin light chains and their association with anti-IgG autoantibodies in essential mixed cryoglobulinaemia, Sjögren's syndrome and rheumatoid arthritis." Immunology.. 1987 Dec; 62(4):529-36.

5/1/1987
Rosenfeld SI, Ryan DH, Looney RJ, Anderson CL, Abraham GN, Leddy JP. "Human Fc gamma receptors: stable inter-donor variation in quantitative expression on platelets correlates with functional responses." The Journal of immunology : official journal of the American Association of Immunologists.. 1987 May 1; 138(9):2869-73.

4/1/1987
Anderson CL, Ryan DH, Looney RJ, Leary PC. "Structural polymorphism of the human monocyte 40 kilodalton Fc receptor for IgG." The Journal of immunology : official journal of the American Association of Immunologists.. 1987 Apr 1; 138(7):2254-6.

1987
Anderson CL, Looney RJ. "Immunoglobulin G Fc receptors of human leukocytes." Methods in enzymology.. 1987 150:524-36.

11/1986
Looney RJ, Steigbigel RT. "Role of the Vi antigen of Salmonella typhi in resistance to host defense in vitro." The Journal of laboratory and clinical medicine.. 1986 Nov; 108(5):506-16.

10/1/1986
O'Grady JH, Looney RJ, Anderson CL. "The valence for ligand of the human mononuclear phagocyte 72 kD high-affinity IgG Fc receptor is one." The Journal of immunology : official journal of the American Association of Immunologists.. 1986 Oct 1; 137(7):2307-10.

9/25/1986
Anderson CL, Guyre PM, Whitin JC, Ryan DH, Looney RJ, Fanger MW. "Monoclonal antibodies to Fc receptors for IgG on human mononuclear phagocytes. Antibody characterization and induction of superoxide production in a monocyte cell line." The Journal of biological chemistry.. 1986 Sep 25; 261(27):12856-64.

6/15/1986
Perl A, Looney RJ, Ryan DH, Abraham GN. "The low affinity 40,000 Fc gamma receptor and the transferrin receptor can be alternative or simultaneous target structures on cells sensitive for natural killing." The Journal of immunology : official journal of the American Association of Immunologists.. 1986 Jun 15; 136(12):4714-20.

4/1/1986
Looney RJ, Ryan DH, Takahashi K, Fleit HB, Cohen HJ, Abraham GN, Anderson CL. "Identification of a second class of IgG Fc receptors on human neutrophils. A 40 kilodalton molecule also found on eosinophils." The Journal of experimental medicine.. 1986 Apr 1; 163(4):826-36.

3/1/1986
Looney RJ, Abraham GN, Anderson CL. "Human monocytes and U937 cells bear two distinct Fc receptors for IgG." The Journal of immunology : official journal of the American Association of Immunologists.. 1986 Mar 1; 136(5):1641-7.

2/1986
Moynihan JA, Looney RJ, Abraham GN. "The V kappa IIIb light chain sub-subgroup. II. Isotype expression in acquired hypogammaglobulinaemia and as a function of age." Immunology.. 1986 Feb; 57(2):325-7.

1986
Anderson, CL.; Looney, RJ. "Human leukocyte IgG Fc receptors". Immunology Today. 1986; 7: 264-266.

12/1985
Rosenfeld SI, Looney RJ, Leddy JP, Phipps DC, Abraham GN, Anderson CL. "Human platelet Fc receptor for immunoglobulin G. Identification as a 40,000-molecular-weight membrane protein shared by monocytes." The Journal of clinical investigation.. 1985 Dec; 76(6):2317-22.

11/1985
Jones DH, Looney RJ, Anderson CL. "Two distinct classes of IgG Fc receptors on a human monocyte line (U937) defined by differences in binding of murine IgG subclasses at low ionic strength." The Journal of immunology : official journal of the American Association of Immunologists.. 1985 Nov; 135(5):3348-53.

2/1985
Moynihan JA, Looney RJ, Abraham GN. "The VKIIIb light chain sub-subgroup: restricted association with mu heavy chain in normal human serum." Immunology.. 1985 Feb; 54(2):207-13.

7/1984
Looney RJ, Abraham GN. "The Fc portion of intact IgG blocks stimulation of human PBMC by anti-T3." The Journal of immunology : official journal of the American Association of Immunologists.. 1984 Jul; 133(1):154-6.

Books & Chapters

2004
Chapter Title: Assessment of the performance of engineered tissues in human requires the development of high sensitivity and quantitative outcome measures
Book Title: Functional Tissue Engineering
Author List: O'Keefe, RJ; Totterman, S; Schwarz, EM; Looney, RJ; Seo, GS; Tamez-Pena, J; Boyd, A; Bukata, S; Monu, J; Parker, K
Edited By: F. Guilak
Published By: Springer2004

2004
Chapter Title: The B cell System
Book Title: Immunologic Disorders in Infants and Children
Author List: Insel, R; Looney, RJ
Edited By: Stiehm
Published By: abc2004

2003
Chapter Title: Occupational Asthma and Industrial Bronchitis
Book Title: Textbook of Pulmonary Medicine
Author List: RJ Looney, MJ Utell
Published By: Lippincott Raven Publishers2003

1998
Chapter Title: Occupational Asthma and Industrial Bronchitis
Book Title: Textbook of Pulmonary Medicine
Author List: RJ Looney, MJ Utell
Published By: Lippincott Raven Publishers1998