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Therapeutic Targeting of Senescent Cells in Lupus

Targeting senescent cells in patients with lupus presents a potential novel approach to disease management and improved clinical outcomes.  While it is known that lupus patients possess cells with a senescence-like phenotype, it is unknown whether these cells would respond to available senolytic drugs.  Studying the effects of these drugs in vitro using patient and lupus mouse model samples will further fundamental insights into the potential role of senolytic drugs in the treatment of lupus.

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Richard J. Looney, M.D.

Richard J. Looney, M.D.
Principal Investigator

November 21, 2025
Rangel-Moreno an International Speaker at the Research Seminars in Biological Sciences and International Biomedicine Workshop

October 22, 2025
Jennifer Anolik Presents at Upstate Medical Center Symposium

October 20, 2025
National Scleroderma Foundation Rochester Education Forum Held at URMC

September 29, 2025
Jessica Stern, MD Awarded a Mentored Patient-Oriented Research Career Development Award (K23)

May 23, 2025
AIR Research Presented at the 2025 AAI Meeting

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  Looney Lab
601 Elmwood Ave/Box 695
Rochester, NY 14642