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Looney Lab

Therapeutic Targeting of Senescent Cells in Lupus

Targeting senescent cells in patients with lupus presents a potential novel approach to disease management and improved clinical outcomes.  While it is known that lupus patients possess cells with a senescence-like phenotype, it is unknown whether these cells would respond to available senolytic drugs.  Studying the effects of these drugs in vitro using patient and lupus mouse model samples will further fundamental insights into the potential role of senolytic drugs in the treatment of lupus.

Richard John Looney, M.D.

Richard John Looney, M.D.
Principal Investigator


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  Looney Lab
601 Elmwood Ave/Box 695
Rochester, NY 14642